BG101288A - Метод и средство за профилактика и лечение на заболявания, причинени от ендотоксини - Google Patents

Метод и средство за профилактика и лечение на заболявания, причинени от ендотоксини

Info

Publication number
BG101288A
BG101288A BG101288A BG10128897A BG101288A BG 101288 A BG101288 A BG 101288A BG 101288 A BG101288 A BG 101288A BG 10128897 A BG10128897 A BG 10128897A BG 101288 A BG101288 A BG 101288A
Authority
BG
Bulgaria
Prior art keywords
preparation
endotoxines
prophylaxy
treatment
caused diseases
Prior art date
Application number
BG101288A
Other languages
English (en)
Other versions
BG61967B1 (bg
Inventor
Daniel Levine
Thomas Parker
Albert Rubin
Bruce Gordon
Stuart Saal
Original Assignee
The Rogosin Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26965092&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG101288(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/288,568 external-priority patent/US5506218A/en
Application filed by The Rogosin Institute filed Critical The Rogosin Institute
Publication of BG101288A publication Critical patent/BG101288A/bg
Publication of BG61967B1 publication Critical patent/BG61967B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1275—Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Методът включва прилагане на препарат, съдържащ фосфолипиди, но свободен от белтъци и пептиди Той може да съдържа триглицериди, други полярни или неутрални липиди, жлъчни киселини или соли на тези киселини.
BG101288A 1994-08-10 1997-03-05 Метод и средство за профилактика и лечение на заболявания,причинени от ендотоксини BG61967B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/288,568 US5506218A (en) 1992-08-12 1994-08-10 Methods useful in endotoxin based therapy
US08/487,459 US5674855A (en) 1992-08-12 1995-06-07 Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions
PCT/US1995/010189 WO1996004916A1 (en) 1994-08-10 1995-08-10 Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions

Publications (2)

Publication Number Publication Date
BG101288A true BG101288A (bg) 1997-09-30
BG61967B1 BG61967B1 (bg) 1998-11-30

Family

ID=26965092

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101288A BG61967B1 (bg) 1994-08-10 1997-03-05 Метод и средство за профилактика и лечение на заболявания,причинени от ендотоксини

Country Status (27)

Country Link
US (1) US5674855A (bg)
EP (1) EP0767666B1 (bg)
JP (1) JP3818660B2 (bg)
CN (1) CN1137688C (bg)
AP (1) AP782A (bg)
AT (1) ATE255415T1 (bg)
AU (1) AU703861C (bg)
BG (1) BG61967B1 (bg)
BR (1) BR9508584A (bg)
CA (1) CA2196906C (bg)
CY (1) CY2514B1 (bg)
CZ (1) CZ287614B6 (bg)
DE (1) DE69532239T2 (bg)
DK (1) DK0767666T3 (bg)
ES (1) ES2211915T3 (bg)
FI (1) FI118035B (bg)
HK (1) HK1003709A1 (bg)
HU (1) HUT77605A (bg)
NO (1) NO313786B1 (bg)
NZ (1) NZ292315A (bg)
OA (2) OA11737A (bg)
PL (1) PL182043B1 (bg)
PT (1) PT767666E (bg)
RO (1) RO115782B1 (bg)
RU (1) RU2174839C2 (bg)
SK (1) SK282493B6 (bg)
WO (1) WO1996004916A1 (bg)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518412B1 (en) 1997-09-29 2003-02-11 Jean-Louis Dasseux Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6004925A (en) 1997-09-29 1999-12-21 J. L. Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6046166A (en) 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6037323A (en) 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
AU3809900A (en) * 1999-03-09 2000-09-28 Max-Delbruck-Centrum Fur Molekulare Medizin Therapy and use of compounds in therapy
US20030032674A1 (en) * 2001-08-13 2003-02-13 Hwang Daniel H. Use of unsaturated fatty acids to treat severe inflammatory diseases
US20040067873A1 (en) 2002-05-17 2004-04-08 Dasseux Jean-Louis H. Method of treating dyslipidemic disorders
CN100462080C (zh) * 2003-02-05 2009-02-18 努特里奇亚有限公司 用于预防和/或治疗脓毒症的肠内组合物
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7622130B2 (en) 2004-05-19 2009-11-24 Los Angeles Biomedical Research Institute at Harbor UCLA-Medical Center Methods and compositions for the non-surgical removal of fat
NZ565590A (en) * 2005-08-29 2010-07-30 Sepsicure L L C Use of a protein free composition comprising cholinic acid and a phosphosphlipid for the treatment or prevention of conditions caused by gram-positive bacteria
GB0522942D0 (en) 2005-11-10 2005-12-21 Leigh Steven Dissolution composition
EP2537526A1 (en) 2006-06-01 2012-12-26 Institut de Cardiologie de Montréal Method and compound for the treatment of valvular stenosis
KR100785656B1 (ko) * 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
PT2396017E (pt) 2009-02-16 2015-10-22 Cerenis Therapeutics Holding Sa Miméticos da apolipoproteína a-i
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US20120237492A1 (en) 2011-02-18 2012-09-20 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
US9023833B2 (en) * 2012-12-18 2015-05-05 Sepsicure, LLC Method for treating sepsis in patients with albumin, cholesterol and HDL levels above minimum thresholds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
DE2556592C2 (de) * 1975-12-16 1986-10-09 A. Nattermann & Cie GmbH, 5000 Köln Arzneimittelzubereitungen auf Basis öliger Lösungen von Phospholipiden
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
IL63734A (en) * 1981-09-04 1985-07-31 Yeda Res & Dev Lipid fraction,its preparation and pharmaceutical compositions containing same
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
JPS6193111A (ja) * 1984-05-28 1986-05-12 Funayama Seizo 発熱性物質除去方法
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
CA2013755C (en) * 1989-04-05 1993-11-30 Simon Benita Medicinal emulsions
DE4017979A1 (de) * 1990-06-05 1991-12-12 Meyer Lucas Gmbh & Co Lipid- bzw. phospholipid-zusammensetzungen sowie diese enthaltendes mittel zur behandlung von erkrankungen sowie auf die zellmembrane zurueckzufuehrende stoerungen
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas

Also Published As

Publication number Publication date
NZ292315A (en) 1998-10-28
RO115782B1 (ro) 2000-06-30
AU703861C (en) 2001-12-20
DK0767666T3 (da) 2004-04-05
HUT77605A (hu) 1998-06-29
NO313786B1 (no) 2002-12-02
AU3405295A (en) 1996-03-07
CA2196906C (en) 2004-03-02
SK282493B6 (sk) 2002-02-05
EP0767666A4 (en) 1998-10-07
PL182043B1 (pl) 2001-10-31
ES2211915T3 (es) 2004-07-16
JP3818660B2 (ja) 2006-09-06
AP782A (en) 1999-11-15
SK17697A3 (en) 1997-09-10
RU2174839C2 (ru) 2001-10-20
CZ287614B6 (en) 2001-01-17
ATE255415T1 (de) 2003-12-15
CN1137688C (zh) 2004-02-11
BR9508584A (pt) 1997-10-21
NO970582D0 (no) 1997-02-07
JPH10504037A (ja) 1998-04-14
CN1158087A (zh) 1997-08-27
WO1996004916A1 (en) 1996-02-22
CY2514B1 (en) 2005-12-23
OA10598A (en) 2002-07-15
DE69532239D1 (de) 2004-01-15
CA2196906A1 (en) 1996-02-22
FI970534A0 (fi) 1997-02-07
EP0767666B1 (en) 2003-12-03
EP0767666A1 (en) 1997-04-16
AP9700921A0 (en) 1997-01-31
OA11737A (en) 2005-05-12
PT767666E (pt) 2004-04-30
NO970582L (no) 1997-04-07
DE69532239T2 (de) 2004-10-21
BG61967B1 (bg) 1998-11-30
PL318593A1 (en) 1997-06-23
FI118035B (fi) 2007-06-15
AU703861B2 (en) 1999-04-01
CZ37197A3 (en) 1997-10-15
US5674855A (en) 1997-10-07
FI970534A (fi) 1997-02-07
HK1003709A1 (en) 1998-11-06

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