BE905255A - Dispositif de distribution a debit controle pour l'administration d'un agent benefique. - Google Patents
Dispositif de distribution a debit controle pour l'administration d'un agent benefique.Info
- Publication number
- BE905255A BE905255A BE0/217033A BE217033A BE905255A BE 905255 A BE905255 A BE 905255A BE 0/217033 A BE0/217033 A BE 0/217033A BE 217033 A BE217033 A BE 217033A BE 905255 A BE905255 A BE 905255A
- Authority
- BE
- Belgium
- Prior art keywords
- beneficial agent
- distribution device
- delivery
- flow rate
- controlled flow
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0068—Rumen, e.g. rumen bolus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- External Artificial Organs (AREA)
Abstract
Dispositif de distribution d'un agent bénéfique, comprenant (1) un logement définissant un espace interne (2) une compositon thermosensible contenant un agent bénéfique dans cet espace, (3) un solute osmotiquement efficace dans cet espace et (4) au moins une voie de passage dans le logement pour débiter l'agent bénéfique depuis ce dispositif de distribution.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/763,493 US4684524A (en) | 1984-03-19 | 1985-08-08 | Rate controlled dispenser for administering beneficial agent |
Publications (1)
Publication Number | Publication Date |
---|---|
BE905255A true BE905255A (fr) | 1986-12-01 |
Family
ID=25067977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/217033A BE905255A (fr) | 1985-08-08 | 1986-08-08 | Dispositif de distribution a debit controle pour l'administration d'un agent benefique. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4684524A (fr) |
JP (1) | JPH0759497B2 (fr) |
AU (3) | AU590308B2 (fr) |
BE (1) | BE905255A (fr) |
BR (1) | BR8603756A (fr) |
CA (1) | CA1265966A (fr) |
DE (1) | DE3626103C2 (fr) |
ES (1) | ES8802113A1 (fr) |
FR (1) | FR2585951B1 (fr) |
GB (1) | GB2178660B (fr) |
IT (1) | IT1195819B (fr) |
NL (1) | NL8601981A (fr) |
NZ (1) | NZ217024A (fr) |
ZA (1) | ZA865982B (fr) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5948769A (en) * | 1984-01-28 | 1999-09-07 | Ismail; Roshdy | Agent for treating heart diseases |
EP0151989B1 (fr) * | 1984-01-28 | 1991-04-10 | Roshdy Dr. Ismail | Moyen de traitement des maladies cardiaques |
US5000957A (en) * | 1984-03-19 | 1991-03-19 | Alza Corporation | Dispenser comprising hydrophilic osmopolymer |
US4844984A (en) * | 1984-03-19 | 1989-07-04 | Alza Corporation | Dispensing system with means for increasing delivery of beneficial agent from the system |
US4814180A (en) * | 1984-03-21 | 1989-03-21 | Alza Corporation | Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container |
US4716496A (en) * | 1986-05-09 | 1987-12-29 | Eaton Corporation | Panel-mounted control station housing |
US4904477A (en) * | 1987-07-08 | 1990-02-27 | American Home Products Corporation | Spray dried ibuprofen compositions |
GB8717168D0 (en) * | 1987-07-21 | 1987-08-26 | Roussel Lab Ltd | Controlled-release device |
US4898734A (en) * | 1988-02-29 | 1990-02-06 | Massachusetts Institute Of Technology | Polymer composite for controlled release or membrane formation |
US4966769A (en) * | 1988-06-02 | 1990-10-30 | Alza Corporation | Method for delivering dosage form for diltiazem |
JP2835051B2 (ja) * | 1988-07-06 | 1998-12-14 | オリンパス光学工業株式会社 | 医療用カプセル |
US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
IL91398A (en) * | 1988-08-30 | 1994-05-30 | Pfizer | A device for the controlled release of pneumatic substances, including the active substance, surrounded by an asymmetric membrane |
IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Hydrogel-operated release devices |
US5108756A (en) * | 1989-01-12 | 1992-04-28 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
US5030452A (en) * | 1989-01-12 | 1991-07-09 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
US5342624A (en) * | 1989-02-16 | 1994-08-30 | British Technology Group Ltd. | Dispensing device |
GB8903564D0 (en) * | 1989-02-16 | 1989-04-05 | Rashid Abdul | Drug dispensing device |
US5206024A (en) * | 1989-04-07 | 1993-04-27 | Alza Corporation | Density element for ruminal delivery device |
US5372776A (en) * | 1989-04-07 | 1994-12-13 | Alza Corporation | Density element and method of manufacture thereof to achieve a particular transverse rupture strength |
US5417976A (en) * | 1989-04-07 | 1995-05-23 | Alza | Density element and method of manufacture thereof |
US5100392A (en) * | 1989-12-08 | 1992-03-31 | Biosynthesis, Inc. | Implantable device for administration of drugs or other liquid solutions |
US5474785A (en) * | 1990-01-24 | 1995-12-12 | Alza Corporation | Delivery system comprising means for controlling internal pressure |
US5223266A (en) * | 1990-01-24 | 1993-06-29 | Alza Corporation | Long-term delivery device with early startup |
US5156623A (en) * | 1990-04-16 | 1992-10-20 | Olympus Optical Co., Ltd. | Sustained release material and method of manufacturing the same |
ES2067957T3 (es) * | 1990-08-07 | 1995-04-01 | Pfizer | Uso de membranas polimerizadas interfacialmente en dispositivos de liberacion. |
BR9106205A (pt) * | 1990-10-31 | 1993-03-30 | Baxter Int | Dispositivo para implantacao em hospedeiro,processo de implantacao,dispositivo implantado,e recipiente de imunoisolamento |
US5713888A (en) * | 1990-10-31 | 1998-02-03 | Baxter International, Inc. | Tissue implant systems |
US5733336A (en) * | 1990-10-31 | 1998-03-31 | Baxter International, Inc. | Ported tissue implant systems and methods of using same |
US5314696A (en) * | 1991-06-27 | 1994-05-24 | Paulos Manley A | Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor |
US5302397A (en) * | 1991-11-19 | 1994-04-12 | Amsden Brian G | Polymer-based drug delivery system |
NZ254424A (en) * | 1992-06-22 | 1997-09-22 | Lunar Corp | Pharmaceutical composition and use of 1 alpha hydroxy-pre-vitamin d |
US5795882A (en) * | 1992-06-22 | 1998-08-18 | Bone Care International, Inc. | Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations |
US5609885A (en) * | 1992-09-15 | 1997-03-11 | Alza Corporation | Osmotic membrane and delivery device |
US5681811A (en) * | 1993-05-10 | 1997-10-28 | Protein Delivery, Inc. | Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same |
US6191105B1 (en) | 1993-05-10 | 2001-02-20 | Protein Delivery, Inc. | Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin |
JPH08511545A (ja) * | 1993-06-14 | 1996-12-03 | エミスフェアー・テクノロジーズ・インコーポレイテッド | プロテイノイド担体並びにその製造方法および使用方法 |
US5651976A (en) * | 1993-06-17 | 1997-07-29 | The United States Of America As Represented By The Secretary Of The Navy | Controlled release of active agents using inorganic tubules |
WO1995008355A1 (fr) * | 1993-09-24 | 1995-03-30 | Baxter International Inc. | Procedes permettant d'ameliorer la vascularisation des dispositifs d'implants |
US6156305A (en) * | 1994-07-08 | 2000-12-05 | Baxter International Inc. | Implanted tumor cells for the prevention and treatment of cancer |
US5607696A (en) * | 1995-02-10 | 1997-03-04 | Alza Corporation | Osmotic membrane and delivery device |
US6395292B2 (en) * | 1996-02-02 | 2002-05-28 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
US6703381B1 (en) * | 1998-08-14 | 2004-03-09 | Nobex Corporation | Methods for delivery therapeutic compounds across the blood-brain barrier |
US6309633B1 (en) | 1999-06-19 | 2001-10-30 | Nobex Corporation | Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same |
US7169889B1 (en) | 1999-06-19 | 2007-01-30 | Biocon Limited | Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin |
US7060675B2 (en) * | 2001-02-15 | 2006-06-13 | Nobex Corporation | Methods of treating diabetes mellitus |
US6867183B2 (en) | 2001-02-15 | 2005-03-15 | Nobex Corporation | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith |
US6828305B2 (en) * | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US7713932B2 (en) | 2001-06-04 | 2010-05-11 | Biocon Limited | Calcitonin drug-oligomer conjugates, and uses thereof |
US6835802B2 (en) * | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
US6713452B2 (en) * | 2001-06-04 | 2004-03-30 | Nobex Corporation | Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US6858580B2 (en) * | 2001-06-04 | 2005-02-22 | Nobex Corporation | Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US6828297B2 (en) | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US7312192B2 (en) * | 2001-09-07 | 2007-12-25 | Biocon Limited | Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
US6913903B2 (en) | 2001-09-07 | 2005-07-05 | Nobex Corporation | Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
US7166571B2 (en) * | 2001-09-07 | 2007-01-23 | Biocon Limited | Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
US7196059B2 (en) | 2001-09-07 | 2007-03-27 | Biocon Limited | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith |
US7601688B2 (en) * | 2002-06-13 | 2009-10-13 | Biocon Limited | Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus |
ES2695401T3 (es) * | 2003-02-12 | 2019-01-04 | Syncera Inc | Composiciones de aleación de polímeros de óxido de alquileno aleatorios y no aleatorios |
CA2580313C (fr) | 2004-07-19 | 2016-03-15 | Biocon Limited | Conjugues insuline-oligomere, preparations et utilisations de ceux-ci |
CA2924200C (fr) * | 2005-10-12 | 2017-09-05 | Proventiv Therapeutics, Llc | Procedes et articles servant a traiter l'insuffisance et la deficience en 25-hydroxyvitamine d |
PL3095447T3 (pl) | 2006-02-03 | 2022-02-14 | Opko Renal, Llc | Leczenie niedoboru lub deficytu witaminy d 25-hydroksywitaminą d2 i 25- hydroksywitaminą d3 |
ES2497494T3 (es) | 2006-06-21 | 2014-09-23 | Opko Renal, Llc | Método de tratamiento y prevención del hiperparatiroidismo secundario |
CA2683514C (fr) | 2007-04-25 | 2019-07-09 | Proventiv Therapeutics, Llc | Procede sur et efficace de traitement et de prevention de l'hyperparathyroidie secondaire dans les maladies renales chroniques |
JP5444212B2 (ja) * | 2007-04-25 | 2014-03-19 | シトクロマ インコーポレイテッド | ビタミンd不足および欠乏症の治療方法 |
KR101540369B1 (ko) | 2007-04-25 | 2015-07-29 | 사이토크로마 인코포레이티드 | 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물 |
JP5647516B2 (ja) * | 2007-04-25 | 2014-12-24 | シトクロマ インコーポレイテッド | ビタミンd療法のための方法および化合物 |
US20130079749A1 (en) * | 2007-08-29 | 2013-03-28 | Advanced Bionics, Llc | Modular Drug Delivery System for Minimizing Trauma During and After Insertion of a Cochlear Lead |
CN101939023B (zh) | 2007-10-16 | 2016-08-03 | 百康有限公司 | 可经口给药的固体药物组合物及其方法 |
EP3112476B1 (fr) | 2008-04-02 | 2023-08-02 | EirGen Pharma Ltd. | Procédés, compositions, utilisations et kits utiles pour la carence en vitamine d et de troubles apparentés |
ES2752923T3 (es) | 2009-07-31 | 2020-04-06 | Boehringer Ingelheim Animal Health Usa Inc | Cápsulas de liberación prolongada |
SI2552484T1 (sl) | 2010-03-29 | 2020-07-31 | Opko Ireland Global Holdings, Ltd. | Postopki in sestavki za znižanje ravni paratiroidnega hormona |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
MY198547A (en) | 2016-03-28 | 2023-09-04 | Opko Ireland Global Holdings Ltd | Methods of vitamin d treatment |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2340037A (en) * | 1941-09-08 | 1944-01-25 | Zipper Alfred Irving | Capsule |
FR1540258A (fr) * | 1964-11-30 | 1968-09-27 | Magnesium Elektron Ltd | Pastilles pour ruminants comportant un corps creux en magnésium ou alliage de magnésium |
US3760804A (en) * | 1971-01-13 | 1973-09-25 | Alza Corp | Improved osmotic dispenser employing magnesium sulphate and magnesium chloride |
US3732865A (en) * | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
US4034756A (en) * | 1971-01-13 | 1977-07-12 | Alza Corporation | Osmotically driven fluid dispenser |
SE376851B (fr) * | 1971-01-13 | 1975-06-16 | Alza Corp | |
US3769895A (en) * | 1971-06-09 | 1973-11-06 | Teletype Corp | Masking for printed circuit photomasters |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3929132A (en) * | 1973-04-10 | 1975-12-30 | Alza Corp | Osmotic dispenser |
US3995632A (en) * | 1973-05-04 | 1976-12-07 | Alza Corporation | Osmotic dispenser |
US4178361A (en) * | 1973-09-10 | 1979-12-11 | Union Corporation | Sustained release pharmaceutical composition |
GB1478759A (en) * | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
DE2729068A1 (de) * | 1977-06-28 | 1979-01-11 | Rainer Dr Med Liedtke | Verfahren zur freisetzungssteuerung von arzneimitteln aus kapseln |
US4196187A (en) * | 1977-09-02 | 1980-04-01 | Eastman Kodak Company | Rumen-stable pellets |
US4199569A (en) * | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
US4200098A (en) * | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
US4285987A (en) * | 1978-10-23 | 1981-08-25 | Alza Corporation | Process for manufacturing device with dispersion zone |
FI63335B (fi) * | 1979-02-02 | 1983-02-28 | Orion Yhtymae Oy | Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne |
US4235236A (en) * | 1979-02-12 | 1980-11-25 | Alza Corporation | Device for dispensing drug by combined diffusional and osmotic operations |
US4320759A (en) * | 1980-04-28 | 1982-03-23 | Alza Corporation | Dispenser with diffuser |
US4389397A (en) * | 1980-08-04 | 1983-06-21 | Merck & Co., Inc. | Solubilization of ivermectin in water |
AU591171B2 (en) * | 1983-11-02 | 1989-11-30 | Alza Corporation | Dispenser for delivering thermo-responsive composition |
US4595583A (en) * | 1984-03-19 | 1986-06-17 | Alza Corporation | Delivery system controlled administration of beneficial agent to ruminants |
FR2565102B1 (fr) * | 1984-06-05 | 1987-03-20 | Paris Sud Universite | Microcapsules biodegradables a base de serumalbumine, leur preparation et leur application a la liberation in situ de medicuments |
JPH0641406A (ja) * | 1992-07-23 | 1994-02-15 | Teijin Ltd | 難燃性ポリエステル樹脂組成物 |
-
1985
- 1985-08-08 US US06/763,493 patent/US4684524A/en not_active Expired - Lifetime
-
1986
- 1986-06-20 ES ES556375A patent/ES8802113A1/es not_active Expired
- 1986-07-30 NZ NZ217024A patent/NZ217024A/xx unknown
- 1986-07-30 GB GB8618568A patent/GB2178660B/en not_active Expired
- 1986-07-31 JP JP61181189A patent/JPH0759497B2/ja not_active Expired - Fee Related
- 1986-08-01 DE DE3626103A patent/DE3626103C2/de not_active Expired - Lifetime
- 1986-08-01 NL NL8601981A patent/NL8601981A/nl unknown
- 1986-08-01 AU AU60780/86A patent/AU590308B2/en not_active Expired
- 1986-08-06 FR FR868611371A patent/FR2585951B1/fr not_active Expired
- 1986-08-06 BR BR8603756A patent/BR8603756A/pt not_active IP Right Cessation
- 1986-08-07 CA CA000515469A patent/CA1265966A/fr not_active Expired - Lifetime
- 1986-08-08 IT IT67646/86A patent/IT1195819B/it active
- 1986-08-08 BE BE0/217033A patent/BE905255A/fr not_active IP Right Cessation
- 1986-08-08 ZA ZA865982A patent/ZA865982B/xx unknown
-
1991
- 1991-11-14 AU AU87886/91A patent/AU8788691A/en not_active Abandoned
- 1991-12-16 AU AU89738/91A patent/AU654515B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
US4684524A (en) | 1987-08-04 |
AU8788691A (en) | 1992-01-16 |
ES556375A0 (es) | 1988-04-01 |
NZ217024A (en) | 1989-07-27 |
IT1195819B (it) | 1988-10-27 |
JPS6239519A (ja) | 1987-02-20 |
GB2178660B (en) | 1989-09-06 |
DE3626103A1 (de) | 1987-02-12 |
NL8601981A (nl) | 1987-03-02 |
ZA865982B (en) | 1987-04-29 |
JPH0759497B2 (ja) | 1995-06-28 |
AU590308B2 (en) | 1989-11-02 |
FR2585951B1 (fr) | 1989-03-03 |
BR8603756A (pt) | 1987-03-10 |
AU8973891A (en) | 1992-02-13 |
GB8618568D0 (en) | 1986-09-10 |
GB2178660A (en) | 1987-02-18 |
CA1265966A (fr) | 1990-02-20 |
AU654515B2 (en) | 1994-11-10 |
AU6078086A (en) | 1987-02-12 |
DE3626103C2 (de) | 1998-02-19 |
IT8667646A0 (it) | 1986-08-08 |
FR2585951A1 (fr) | 1987-02-13 |
ES8802113A1 (es) | 1988-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE20 | Patent expired |
Owner name: *ALZA CORP. Effective date: 20060808 |