BE903785A - Nouveau sel soluble presentant une activite analgesique et anti-inflammatoire, methode de preparation et formes pharmaceutiques contenant ce sel. - Google Patents

Nouveau sel soluble presentant une activite analgesique et anti-inflammatoire, methode de preparation et formes pharmaceutiques contenant ce sel.

Info

Publication number
BE903785A
BE903785A BE0/215960A BE215960A BE903785A BE 903785 A BE903785 A BE 903785A BE 0/215960 A BE0/215960 A BE 0/215960A BE 215960 A BE215960 A BE 215960A BE 903785 A BE903785 A BE 903785A
Authority
BE
Belgium
Prior art keywords
salt
analgesic
preparation
inflammatory activity
pharmaceutical forms
Prior art date
Application number
BE0/215960A
Other languages
English (en)
Original Assignee
Istituto Biochimo Pavese S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Biochimo Pavese S P A filed Critical Istituto Biochimo Pavese S P A
Publication of BE903785A publication Critical patent/BE903785A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Le D-6-méthoxy-alpha-méthyl-2-naphtalène-acétate du sel sodique de l-carboxy-N,N', N''-triméthyl-méthanamine de formule I, préparé par réaction entre le sel sodique de 1-carboxy-N-N', N'' triméthyl-méthanamine et l'acide D-6-méthoxy-méthyl-2-naphtalène-acétique, à une température comprise entre 10 et 30 degrés C, présente une absorption meilleure et plus rapide et une plus grande tolérance au niveau de la muqueuse gastrique. Le composé présente une activité analgésique.
BE0/215960A 1984-12-05 1985-12-04 Nouveau sel soluble presentant une activite analgesique et anti-inflammatoire, methode de preparation et formes pharmaceutiques contenant ce sel. BE903785A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23897/84A IT1196356B (it) 1984-12-05 1984-12-05 Sale solubile avente attivita' anti-infiammatoria,procedimento per la sua preparazione e forme farmaceutiche contenenti lo stesso

Publications (1)

Publication Number Publication Date
BE903785A true BE903785A (fr) 1986-04-01

Family

ID=11210728

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215960A BE903785A (fr) 1984-12-05 1985-12-04 Nouveau sel soluble presentant une activite analgesique et anti-inflammatoire, methode de preparation et formes pharmaceutiques contenant ce sel.

Country Status (8)

Country Link
US (1) US4672077A (fr)
JP (1) JPS62286956A (fr)
BE (1) BE903785A (fr)
CH (1) CH663783A5 (fr)
DE (1) DE3542906C2 (fr)
ES (1) ES8701146A1 (fr)
FR (1) FR2574076B1 (fr)
IT (1) IT1196356B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1208302B (de) * 1962-08-28 1966-01-05 Novo Terapeutisk Labor As Verfahren zur Herstellung von D(-)- und L(ú½)-alpha-Aminobenzylpenicillin

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2794045A (en) * 1953-11-09 1957-05-28 Beaufour Henri Monobetaine citrate
US3002886A (en) * 1958-03-03 1961-10-03 Synergistics Inc Betaine salicylates and the method for their preparation
DE1195767B (de) * 1961-01-10 1965-07-01 Mundipharma Ag Verfahren zur Herstellung eines therapeutisch verwendbaren Salicylsaeuresalzes
GB950505A (en) * 1961-01-10 1964-02-26 Mundipharma Ag Improvements in betaine salicylates and the method for their preparation
FR1391M (fr) * 1961-07-01 1962-07-09 Jacques Emile Cailliot 1-bromo 2-hydroxy 3-naphtoate de bétaine.
US3242048A (en) * 1962-06-20 1966-03-22 Synergistics Inc Betaine glutamate and methods of using same
FR1479304A (fr) * 1966-02-16 1967-05-05 Sapchim Fournier Cimag Soc Nouveaux dérivés aminés de l'acide gentisique et procédés de fabrication
BR6915470D0 (pt) * 1969-03-24 1973-03-13 Syntex Corp Processo para preparar derivados de acido 2-(6'substituido 2'naftil)propionico e de seus sais
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
US4080472A (en) * 1974-03-22 1978-03-21 Societe D'etudes Et D'exploitation De Marques Et Brevets S.E.M.S. Metformin 2-(p-chlorophenoxy)-2-methylpropionate
DE2935776A1 (de) * 1979-09-05 1981-04-16 Theodor Prof. Dr. 4400 Münster Eckert Organische salze des indometacin, des naproxen und des diclofenac, ihre herstellung und sie enthaltende arzneimittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1208302B (de) * 1962-08-28 1966-01-05 Novo Terapeutisk Labor As Verfahren zur Herstellung von D(-)- und L(ú½)-alpha-Aminobenzylpenicillin

Also Published As

Publication number Publication date
ES549534A0 (es) 1986-12-01
JPS62286956A (ja) 1987-12-12
CH663783A5 (it) 1988-01-15
DE3542906A1 (de) 1986-06-12
ES8701146A1 (es) 1986-12-01
FR2574076A1 (fr) 1986-06-06
US4672077A (en) 1987-06-09
IT1196356B (it) 1988-11-16
IT8423897A0 (it) 1984-12-05
DE3542906C2 (de) 1995-06-14
FR2574076B1 (fr) 1989-07-28

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: S.A. APR TRADING

Effective date: 19981231