GB950505A - Improvements in betaine salicylates and the method for their preparation - Google Patents

Improvements in betaine salicylates and the method for their preparation

Info

Publication number
GB950505A
GB950505A GB101561A GB101561A GB950505A GB 950505 A GB950505 A GB 950505A GB 101561 A GB101561 A GB 101561A GB 101561 A GB101561 A GB 101561A GB 950505 A GB950505 A GB 950505A
Authority
GB
United Kingdom
Prior art keywords
betaine
preparation
salicylate
preparations
salicylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB101561A
Inventor
Alfred Halpern
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mundipharma AG
Original Assignee
Mundipharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma AG filed Critical Mundipharma AG
Priority to GB101561A priority Critical patent/GB950505A/en
Priority to DEM47722A priority patent/DE1195767B/en
Publication of GB950505A publication Critical patent/GB950505A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • C07C65/10Salicylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention comprises betaine salicylate, and the preparation thereof by reacting, in an inert organic solvent, betaine with salicylic acid, or a betaine salt with a salicylic acid salt. The invention further comprises solid therapeutic preparations in unit dosage form (e.g. tablets, capsules and suppositories) containing 50-500 mg. of betaine salicylate, and liquid therapeutic preparations comprising betaine salicylate in an aqueous alcoholic medium. The preparations are useful for treating rheumatic disease and as analgesic agents.
GB101561A 1961-01-10 1961-01-10 Improvements in betaine salicylates and the method for their preparation Expired GB950505A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB101561A GB950505A (en) 1961-01-10 1961-01-10 Improvements in betaine salicylates and the method for their preparation
DEM47722A DE1195767B (en) 1961-01-10 1961-01-18 Process for the preparation of a therapeutically useful salicylic acid salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB101561A GB950505A (en) 1961-01-10 1961-01-10 Improvements in betaine salicylates and the method for their preparation

Publications (1)

Publication Number Publication Date
GB950505A true GB950505A (en) 1964-02-26

Family

ID=9714657

Family Applications (1)

Application Number Title Priority Date Filing Date
GB101561A Expired GB950505A (en) 1961-01-10 1961-01-10 Improvements in betaine salicylates and the method for their preparation

Country Status (1)

Country Link
GB (1) GB950505A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3542906A1 (en) * 1984-12-05 1986-06-12 Istituto Biochimico Pavese Spa, Pavia ANTI-INFLAMMATORY ANALGETIC COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS
CN110724048A (en) * 2019-09-19 2020-01-24 杭州海尔希畜牧科技有限公司 Preparation method of malic acid betaine (1: 1)
CN113440428A (en) * 2021-06-10 2021-09-28 纳爱斯浙江科技有限公司 Efficient mild bacteriostatic agent suitable for various surfactant systems and application thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3542906A1 (en) * 1984-12-05 1986-06-12 Istituto Biochimico Pavese Spa, Pavia ANTI-INFLAMMATORY ANALGETIC COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS
CN110724048A (en) * 2019-09-19 2020-01-24 杭州海尔希畜牧科技有限公司 Preparation method of malic acid betaine (1: 1)
CN110724048B (en) * 2019-09-19 2022-05-10 杭州海尔希畜牧科技有限公司 Preparation method of malic acid betaine (1: 1)
CN113440428A (en) * 2021-06-10 2021-09-28 纳爱斯浙江科技有限公司 Efficient mild bacteriostatic agent suitable for various surfactant systems and application thereof

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