BE896572A - Benzoazacycloalkyl-spiro-imidazolidines leur preparation et leur application en therapeutique - Google Patents
Benzoazacycloalkyl-spiro-imidazolidines leur preparation et leur application en therapeutiqueInfo
- Publication number
- BE896572A BE896572A BE0/210633A BE210633A BE896572A BE 896572 A BE896572 A BE 896572A BE 0/210633 A BE0/210633 A BE 0/210633A BE 210633 A BE210633 A BE 210633A BE 896572 A BE896572 A BE 896572A
- Authority
- BE
- Belgium
- Prior art keywords
- benzoazacycloalkyl
- imidazolidines
- spiro
- therapeutics
- preparation
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8207203A FR2525603A1 (fr) | 1982-04-27 | 1982-04-27 | Benzoazacycloalkyl-spiro-imidazolinines, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE896572A true BE896572A (fr) | 1983-10-26 |
Family
ID=9273425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/210633A BE896572A (fr) | 1982-04-27 | 1983-04-26 | Benzoazacycloalkyl-spiro-imidazolidines leur preparation et leur application en therapeutique |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5910584A (OSRAM) |
| KR (1) | KR840004428A (OSRAM) |
| AT (1) | ATA125383A (OSRAM) |
| AU (1) | AU1395383A (OSRAM) |
| BE (1) | BE896572A (OSRAM) |
| DD (1) | DD209833A5 (OSRAM) |
| DE (1) | DE3315106A1 (OSRAM) |
| DK (1) | DK183583A (OSRAM) |
| ES (1) | ES521895A0 (OSRAM) |
| FR (1) | FR2525603A1 (OSRAM) |
| GB (1) | GB2133401B (OSRAM) |
| GR (1) | GR78481B (OSRAM) |
| IL (1) | IL68497A0 (OSRAM) |
| IT (1) | IT1167123B (OSRAM) |
| LU (1) | LU84770A1 (OSRAM) |
| MA (1) | MA19783A1 (OSRAM) |
| NL (1) | NL8301476A (OSRAM) |
| NO (1) | NO831473L (OSRAM) |
| OA (1) | OA07412A (OSRAM) |
| PT (1) | PT76595B (OSRAM) |
| SE (1) | SE8302347L (OSRAM) |
| ZA (1) | ZA832927B (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU617541B2 (en) * | 1988-10-20 | 1991-11-28 | Wyeth | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US4927831A (en) * | 1988-10-20 | 1990-05-22 | American Home Products | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| WO2005019179A2 (en) | 2003-06-17 | 2005-03-03 | Arena Pharmaceuticals, Inc. | Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases |
| NZ578503A (en) | 2003-06-17 | 2011-02-25 | Arena Pharm Inc | Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases |
| WO2006069363A2 (en) | 2004-12-21 | 2006-06-29 | Arena Pharmaceuticals, Inc. | Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride |
| DK1833473T3 (da) | 2004-12-23 | 2010-01-11 | Arena Pharm Inc | 5HT2C-Receptormodulator-sammensætninger og metoder for anvendelse |
| EP2001852A2 (en) | 2006-04-03 | 2008-12-17 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto |
| EP2099743B1 (en) | 2006-12-05 | 2014-08-27 | Arena Pharmaceuticals, Inc. | Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof |
| JP5491421B2 (ja) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ５−ｈｔ２ｃアゴニストである（ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンに関連する中間体の調製のためのプロセス |
| WO2010148207A2 (en) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| CN103189360A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 5-ht2c激动剂的非吸湿性盐 |
| CA2808909A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids |
| KR20140091458A (ko) | 2010-09-01 | 2014-07-21 | 아레나 파마슈티칼스, 인크. | 신장 손상을 갖는 개체에 대한 로카세린의 투여 |
| CN107669687A (zh) | 2010-09-01 | 2018-02-09 | 艾尼纳制药公司 | 用于体重控制的5‑ht2c激动剂的调节释放剂型 |
| JP2015534563A (ja) | 2012-10-09 | 2015-12-03 | アリーナ ファーマシューティカルズ， インコーポレイテッド | 体重管理の方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4209630A (en) * | 1976-10-18 | 1980-06-24 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
-
1982
- 1982-04-27 FR FR8207203A patent/FR2525603A1/fr active Granted
-
1983
- 1983-04-08 AT AT0125383A patent/ATA125383A/de not_active IP Right Cessation
- 1983-04-25 DD DD83250187A patent/DD209833A5/de unknown
- 1983-04-25 LU LU84770A patent/LU84770A1/fr unknown
- 1983-04-26 SE SE8302347A patent/SE8302347L/xx not_active Application Discontinuation
- 1983-04-26 GR GR71214A patent/GR78481B/el unknown
- 1983-04-26 ZA ZA832927A patent/ZA832927B/xx unknown
- 1983-04-26 BE BE0/210633A patent/BE896572A/fr not_active IP Right Cessation
- 1983-04-26 IT IT48155/83A patent/IT1167123B/it active
- 1983-04-26 DK DK183583A patent/DK183583A/da not_active Application Discontinuation
- 1983-04-26 JP JP58073687A patent/JPS5910584A/ja active Pending
- 1983-04-26 NL NL8301476A patent/NL8301476A/nl not_active Application Discontinuation
- 1983-04-26 PT PT76595A patent/PT76595B/pt unknown
- 1983-04-26 AU AU13953/83A patent/AU1395383A/en not_active Abandoned
- 1983-04-26 KR KR1019830001753A patent/KR840004428A/ko not_active Withdrawn
- 1983-04-26 NO NO831473A patent/NO831473L/no unknown
- 1983-04-26 IL IL68497A patent/IL68497A0/xx unknown
- 1983-04-27 ES ES521895A patent/ES521895A0/es active Granted
- 1983-04-27 OA OA57984A patent/OA07412A/xx unknown
- 1983-04-27 DE DE19833315106 patent/DE3315106A1/de not_active Withdrawn
- 1983-04-27 MA MA20003A patent/MA19783A1/fr unknown
- 1983-04-27 GB GB08311508A patent/GB2133401B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2133401B (en) | 1985-10-23 |
| DE3315106A1 (de) | 1983-11-03 |
| NO831473L (no) | 1983-10-28 |
| NL8301476A (nl) | 1983-11-16 |
| IT1167123B (it) | 1987-05-13 |
| GB8311508D0 (en) | 1983-06-02 |
| KR840004428A (ko) | 1984-10-15 |
| IL68497A0 (en) | 1983-07-31 |
| MA19783A1 (fr) | 1983-12-31 |
| DD209833A5 (de) | 1984-05-23 |
| PT76595A (fr) | 1983-05-01 |
| SE8302347D0 (sv) | 1983-04-26 |
| OA07412A (fr) | 1984-11-30 |
| IT8348155A0 (it) | 1983-04-26 |
| FR2525603B1 (OSRAM) | 1984-09-14 |
| GB2133401A (en) | 1984-07-25 |
| ATA125383A (de) | 1986-05-15 |
| SE8302347L (sv) | 1983-10-28 |
| LU84770A1 (fr) | 1984-11-28 |
| ZA832927B (en) | 1984-06-27 |
| ES8405796A1 (es) | 1984-06-16 |
| DK183583A (da) | 1983-10-28 |
| DK183583D0 (da) | 1983-04-26 |
| JPS5910584A (ja) | 1984-01-20 |
| ES521895A0 (es) | 1984-06-16 |
| FR2525603A1 (fr) | 1983-10-28 |
| GR78481B (OSRAM) | 1984-09-27 |
| AU1395383A (en) | 1983-11-03 |
| PT76595B (fr) | 1986-01-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA19845A1 (fr) | Nouvelles piperidinamines et leur preparation | |
| ES502384A0 (es) | Perfeccionamientos en aparatos para abarcar y elaborar sena-les electricas | |
| SG3489G (en) | Improvements in and relating to cutlery | |
| BR1100036A (pt) | Composto e composição farmacêutica | |
| BE888864A (fr) | Substances anticoagulantes et leur preparation | |
| BE877394A (fr) | Phenethanolamines et leur utilisation therapeutique | |
| BE896572A (fr) | Benzoazacycloalkyl-spiro-imidazolidines leur preparation et leur application en therapeutique | |
| ES534446A0 (es) | Perfeccionamientos en fonocardiografos y electrocardiografos | |
| LU80922A1 (fr) | 9-amino-et imino-dibenzopyrannes et leur utilisation therapeutique | |
| FR2606410B1 (fr) | Imidazopyridines, leur preparation et leur application en therapeutique | |
| FR2553777B1 (fr) | Nouveaux complexes de platine et leur application en therapeutique | |
| DE3378954D1 (en) | Perfluorocarbon emulsions and their preparation and use in therapy | |
| BE896018A (fr) | Amides pyrrolacetiques, leur preparation et leur utilisation | |
| IT1194436B (it) | Metodo per formare ondulazione permanenti nei capelli | |
| FR2543140B1 (fr) | Nouveaux acides flavone-carboxyliques-4', leur methode de preparation et leur application en therapeutique | |
| BE882166A (fr) | 9-aminoalkylfluorenes, leur preparation et leur utilisation therapeutique | |
| BR8801758A (pt) | Composicao em particulas | |
| BE876938A (fr) | Nouveaux composes bis(aryloxycarboxyliques) leur preparation et leur utilisation en therapeutique | |
| GB2122875B (en) | Improvements in and relating to cutlery | |
| FR2352804A1 (fr) | 4-quinazolinyl-guanidines, leur preparation et leur application en therapeutique | |
| FR2542744B2 (fr) | 3',5'-diarabinosides, leur preparation et leur application en therapeutique | |
| ZA834344B (en) | Use of 1,4-dihydropyridines in antiarteriosclerotic agents and their preparation | |
| GB2133056B (en) | Improvements in and/or relating to cribwalling | |
| FR2542745B1 (fr) | Polysaccharide, sa preparation et son application en therapeutique | |
| FR2544308B1 (fr) | Ethines substituees, leur preparation et leur application en therapeutique |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: ADIR Effective date: 19860430 |