BE889757A - Nouvelles oxazolidine -2,4- diones substituees en position 5 douees d'activite hypoglycemique - Google Patents

Nouvelles oxazolidine -2,4- diones substituees en position 5 douees d'activite hypoglycemique Download PDF

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Publication number
BE889757A
BE889757A BE0/205505A BE205505A BE889757A BE 889757 A BE889757 A BE 889757A BE 0/205505 A BE0/205505 A BE 0/205505A BE 205505 A BE205505 A BE 205505A BE 889757 A BE889757 A BE 889757A
Authority
BE
Belgium
Prior art keywords
emi
fluoro
chloro
radical
formula
Prior art date
Application number
BE0/205505A
Other languages
English (en)
French (fr)
Inventor
R C Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE889757A publication Critical patent/BE889757A/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE0/205505A 1980-07-28 1981-07-27 Nouvelles oxazolidine -2,4- diones substituees en position 5 douees d'activite hypoglycemique BE889757A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17320680A 1980-07-28 1980-07-28

Publications (1)

Publication Number Publication Date
BE889757A true BE889757A (fr) 1982-01-27

Family

ID=22630977

Family Applications (2)

Application Number Title Priority Date Filing Date
BE0/205505A BE889757A (fr) 1980-07-28 1981-07-27 Nouvelles oxazolidine -2,4- diones substituees en position 5 douees d'activite hypoglycemique
BE0/205506A BE889758A (fr) 1980-07-28 1981-07-27 Oxazolidine-2,4-diones substituees en position 5 a action hypoglycemique

Family Applications After (1)

Application Number Title Priority Date Filing Date
BE0/205506A BE889758A (fr) 1980-07-28 1981-07-27 Oxazolidine-2,4-diones substituees en position 5 a action hypoglycemique

Country Status (4)

Country Link
JP (1) JPS5758676A (es)
BE (2) BE889757A (es)
GT (2) GT198170555A (es)
ZA (2) ZA815126B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617312A (en) * 1983-01-17 1986-10-14 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones
EP0097453B1 (en) * 1982-06-23 1990-04-11 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0097453B1 (en) * 1982-06-23 1990-04-11 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4617312A (en) * 1983-01-17 1986-10-14 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones

Also Published As

Publication number Publication date
JPS6135188B2 (es) 1986-08-12
ZA815133B (en) 1982-07-28
JPS5758676A (en) 1982-04-08
GT198170554A (es) 1983-01-12
ZA815126B (en) 1983-02-23
GT198170555A (es) 1983-01-12
BE889758A (fr) 1982-01-27

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PFIZER INC.

Effective date: 19900731