BE887566A - Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant - Google Patents
Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenantInfo
- Publication number
- BE887566A BE887566A BE0/203830A BE203830A BE887566A BE 887566 A BE887566 A BE 887566A BE 0/203830 A BE0/203830 A BE 0/203830A BE 203830 A BE203830 A BE 203830A BE 887566 A BE887566 A BE 887566A
- Authority
- BE
- Belgium
- Prior art keywords
- phenylacetics
- hedroxybenzyl
- amides
- alpha
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12254480A | 1980-02-19 | 1980-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE887566A true BE887566A (fr) | 1981-06-15 |
Family
ID=22403319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/203830A BE887566A (fr) | 1980-02-19 | 1981-02-18 | Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS56131552A (nl) |
| AU (1) | AU538240B2 (nl) |
| BE (1) | BE887566A (nl) |
| CA (1) | CA1156655A (nl) |
| CH (1) | CH648283A5 (nl) |
| DE (1) | DE3105285A1 (nl) |
| FR (1) | FR2476071A1 (nl) |
| GB (1) | GB2071086B (nl) |
| IL (1) | IL61945A (nl) |
| IT (1) | IT1146744B (nl) |
| NL (1) | NL8100808A (nl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA805476B (en) * | 1979-09-26 | 1981-11-25 | Robins Co Inc A H | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
| IL64724A0 (en) * | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
| US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
| AR030346A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico |
| AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
| AU2002247284A1 (en) | 2001-04-02 | 2002-10-15 | Alcon, Inc. | Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac |
| TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
| EP2389355A1 (en) * | 2009-03-12 | 2011-11-30 | Medichem, S.A. | New crystals of a benzoylbenzeneacetamide derivative |
| CN102421747A (zh) * | 2009-04-06 | 2012-04-18 | 麦迪凯姆股份公司 | 2-{2-氨基-3-[羟基(苯基)甲基]苯基}乙酰胺 |
| CN106631881B (zh) * | 2016-09-08 | 2018-09-21 | 南京工业大学 | 2-（3-苄基-2-（二甲基氨基）苯基）乙酰胺及合成方法和用途 |
| CN112794809B (zh) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | 一种高纯度奈帕芬胺中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE400966B (sv) * | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror |
| FR2366015A1 (fr) * | 1975-11-05 | 1978-04-28 | Robins Co Inc A H | Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation |
| ZA805476B (en) * | 1979-09-26 | 1981-11-25 | Robins Co Inc A H | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
-
1981
- 1981-01-20 IL IL61945A patent/IL61945A/xx unknown
- 1981-02-09 IT IT67177/81A patent/IT1146744B/it active
- 1981-02-13 DE DE19813105285 patent/DE3105285A1/de not_active Withdrawn
- 1981-02-16 AU AU67330/81A patent/AU538240B2/en not_active Ceased
- 1981-02-18 CA CA000371185A patent/CA1156655A/en not_active Expired
- 1981-02-18 BE BE0/203830A patent/BE887566A/fr not_active IP Right Cessation
- 1981-02-18 FR FR8103188A patent/FR2476071A1/fr active Granted
- 1981-02-18 NL NL8100808A patent/NL8100808A/nl not_active Application Discontinuation
- 1981-02-18 GB GB8105091A patent/GB2071086B/en not_active Expired
- 1981-02-18 CH CH1076/81A patent/CH648283A5/fr not_active IP Right Cessation
- 1981-02-19 JP JP2363881A patent/JPS56131552A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56131552A (en) | 1981-10-15 |
| DE3105285A1 (de) | 1982-01-21 |
| IT1146744B (it) | 1986-11-19 |
| CH648283A5 (fr) | 1985-03-15 |
| FR2476071A1 (fr) | 1981-08-21 |
| CA1156655A (en) | 1983-11-08 |
| JPH0153266B2 (nl) | 1989-11-13 |
| AU6733081A (en) | 1981-08-27 |
| IL61945A (en) | 1984-09-30 |
| AU538240B2 (en) | 1984-08-02 |
| IT8167177A0 (it) | 1981-02-09 |
| GB2071086A (en) | 1981-09-16 |
| NL8100808A (nl) | 1981-09-16 |
| GB2071086B (en) | 1984-02-08 |
| FR2476071B1 (nl) | 1984-05-11 |
| IL61945A0 (en) | 1981-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: A.H. ROBINS CY INC. Effective date: 19920228 |