BE887566A - Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant - Google Patents

Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant

Info

Publication number
BE887566A
BE887566A BE0/203830A BE203830A BE887566A BE 887566 A BE887566 A BE 887566A BE 0/203830 A BE0/203830 A BE 0/203830A BE 203830 A BE203830 A BE 203830A BE 887566 A BE887566 A BE 887566A
Authority
BE
Belgium
Prior art keywords
phenylacetics
hedroxybenzyl
amides
alpha
esters
Prior art date
Application number
BE0/203830A
Other languages
English (en)
French (fr)
Inventor
W J Welstead
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of BE887566A publication Critical patent/BE887566A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE0/203830A 1980-02-19 1981-02-18 Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant BE887566A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12254480A 1980-02-19 1980-02-19

Publications (1)

Publication Number Publication Date
BE887566A true BE887566A (fr) 1981-06-15

Family

ID=22403319

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/203830A BE887566A (fr) 1980-02-19 1981-02-18 Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant

Country Status (11)

Country Link
JP (1) JPS56131552A (it)
AU (1) AU538240B2 (it)
BE (1) BE887566A (it)
CA (1) CA1156655A (it)
CH (1) CH648283A5 (it)
DE (1) DE3105285A1 (it)
FR (1) FR2476071A1 (it)
GB (1) GB2071086B (it)
IL (1) IL61945A (it)
IT (1) IT1146744B (it)
NL (1) NL8100808A (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AU2002247284A1 (en) 2001-04-02 2002-10-15 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
EP2389355A1 (en) * 2009-03-12 2011-11-30 Medichem, S.A. New crystals of a benzoylbenzeneacetamide derivative
CN102421747A (zh) * 2009-04-06 2012-04-18 麦迪凯姆股份公司 2-{2-氨基-3-[羟基(苯基)甲基]苯基}乙酰胺
CN106631881B (zh) * 2016-09-08 2018-09-21 南京工业大学 2-(3-苄基-2-(二甲基氨基)苯基)乙酰胺及合成方法和用途
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
FR2366015A1 (fr) * 1975-11-05 1978-04-28 Robins Co Inc A H Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Also Published As

Publication number Publication date
JPS56131552A (en) 1981-10-15
DE3105285A1 (de) 1982-01-21
IT1146744B (it) 1986-11-19
CH648283A5 (fr) 1985-03-15
FR2476071A1 (fr) 1981-08-21
CA1156655A (en) 1983-11-08
JPH0153266B2 (it) 1989-11-13
AU6733081A (en) 1981-08-27
IL61945A (en) 1984-09-30
AU538240B2 (en) 1984-08-02
IT8167177A0 (it) 1981-02-09
GB2071086A (en) 1981-09-16
NL8100808A (nl) 1981-09-16
GB2071086B (en) 1984-02-08
FR2476071B1 (it) 1984-05-11
IL61945A0 (en) 1981-02-27

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: A.H. ROBINS CY INC.

Effective date: 19920228