BE869915A - Procede de preparation de microspheres comportant un noyau solide et une matiere polymere - Google Patents

Procede de preparation de microspheres comportant un noyau solide et une matiere polymere

Info

Publication number
BE869915A
BE869915A BE190031A BE190031A BE869915A BE 869915 A BE869915 A BE 869915A BE 190031 A BE190031 A BE 190031A BE 190031 A BE190031 A BE 190031A BE 869915 A BE869915 A BE 869915A
Authority
BE
Belgium
Prior art keywords
polymeric material
solid core
preparing microspheres
microspheres
preparing
Prior art date
Application number
BE190031A
Other languages
English (en)
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE869915A publication Critical patent/BE869915A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/025—Explicitly spheroidal or spherical shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/624—Coated by macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/654—The particulate/core comprising macromolecular material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
BE190031A 1977-08-25 1978-08-23 Procede de preparation de microspheres comportant un noyau solide et une matiere polymere BE869915A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82771077A 1977-08-25 1977-08-25

Publications (1)

Publication Number Publication Date
BE869915A true BE869915A (fr) 1979-02-23

Family

ID=25249947

Family Applications (1)

Application Number Title Priority Date Filing Date
BE190031A BE869915A (fr) 1977-08-25 1978-08-23 Procede de preparation de microspheres comportant un noyau solide et une matiere polymere

Country Status (21)

Country Link
JP (1) JPS5455717A (it)
AT (1) AT372019B (it)
AU (1) AU522215B2 (it)
BE (1) BE869915A (it)
CA (1) CA1122077A (it)
CH (2) CH644768A5 (it)
DE (1) DE2836044A1 (it)
DK (2) DK361878A (it)
ES (1) ES472800A1 (it)
FI (1) FI64899C (it)
FR (1) FR2400950A1 (it)
GB (1) GB2003108B (it)
IE (1) IE47255B1 (it)
IL (1) IL55418A (it)
IT (1) IT1098111B (it)
NL (1) NL7808613A (it)
NZ (1) NZ188232A (it)
PH (1) PH15447A (it)
PT (1) PT68473A (it)
SE (1) SE431942B (it)
ZA (1) ZA784855B (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045845B2 (ja) * 1979-10-31 1985-10-12 田辺製薬株式会社 医薬物質含有マイクロカプセルの製法
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
JPS5933214A (ja) * 1982-08-19 1984-02-23 Mitsui Toatsu Chem Inc 微小球に製剤された制ガン剤の製造方法
AT382076B (de) * 1982-10-15 1987-01-12 Chemie Linz Ag Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
DE3417576A1 (de) * 1984-05-11 1985-11-14 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Retardformen des alpha-(2,5-dimethoxy-phenyl)-ss-glycinamidoaethanols und verfahren zu ihrer herstellung
DE3428372A1 (de) * 1984-08-01 1986-02-13 Hoechst Ag, 6230 Frankfurt Mikrokapseln von regulatorischen peptiden mit kontrollierter freisetzung, verfahren zu ihrer herstellung und injektionszubereitungen
CH660302A5 (fr) * 1984-10-17 1987-04-15 Debiopharm Sa Procede de micro-encapsulation en phase heterogene de substances medicamenteuses hydrosolubles.
CH669506A5 (en) * 1986-01-13 1989-03-31 Hugo Degen Oscillating and reclining furniture
DE3712095A1 (de) * 1987-04-10 1988-10-20 Lentia Gmbh Bindemittelfreies granulat mit verzoegerter wirkstoffabgabe
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
FR2657255B1 (fr) * 1989-12-27 1992-04-24 Sederma Sa Description de preparations cosmetiques originales dont les principes actifs sont pieges dans un reseau polymerique greffe a la surface de particules de silice.
DE4127757A1 (de) * 1991-02-06 1992-08-13 Hoechst Ag Neue pflanzenschutzmittel-formulierungen
US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
US6787090B2 (en) 2000-05-12 2004-09-07 Matregen Corp. Method of producing structures using centrifugal forces
US6969480B2 (en) 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces
US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
EP2219775A4 (en) * 2007-12-11 2012-10-03 Univ Nanyang Tech MULTILAYERED HOLLOW MICROSPHERES FOR THE ADMINISTRATION OF HYDROPHILIC ACTIVE COMPOUNDS
TWI400278B (zh) * 2008-05-21 2013-07-01 Toray Industries 聚合物微粒子之製法
CN103828801B (zh) * 2014-01-15 2016-01-27 福建农林大学 多杀菌素/甲氨基阿维菌素苯甲酸盐微球及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT631615A (it) * 1960-02-26
US3427250A (en) * 1963-03-25 1969-02-11 Polaroid Corp Microscopic capsules and process for their preparation
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
FR1497584A (fr) * 1966-08-11 1967-10-13 Roussel Uclaf Procédé de fabrication de microcapsules
US3703474A (en) * 1967-08-21 1972-11-21 Ncr Co Encapsulation process
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
JPS51125675A (en) * 1975-02-13 1976-11-02 Asahi Chem Ind Co Ltd A porous capsule structvre and a process for manufacturing turing it

Also Published As

Publication number Publication date
GB2003108B (en) 1982-03-24
AU522215B2 (en) 1982-05-20
AU3923678A (en) 1980-02-28
ES472800A1 (es) 1979-10-16
SE7808759L (sv) 1979-02-26
SE431942B (sv) 1984-03-12
IL55418A (en) 1981-07-31
PH15447A (en) 1983-01-18
IE47255B1 (en) 1984-02-08
CH644768A5 (de) 1984-08-31
JPS645005B2 (it) 1989-01-27
DK361878A (da) 1979-02-26
NZ188232A (en) 1980-12-19
FI782501A (fi) 1979-02-26
PT68473A (fr) 1978-09-01
DE2836044C2 (it) 1988-06-23
IL55418A0 (en) 1978-10-31
IT1098111B (it) 1985-09-07
AT372019B (de) 1983-08-25
FI64899C (fi) 1984-02-10
FI64899B (fi) 1983-10-31
FR2400950A1 (fr) 1979-03-23
GB2003108A (en) 1979-03-07
DK618189D0 (da) 1989-12-07
FR2400950B1 (it) 1983-10-07
CH649217A5 (de) 1985-05-15
NL7808613A (nl) 1979-02-27
IT7826961A0 (it) 1978-08-23
DE2836044A1 (de) 1979-03-01
CA1122077A (en) 1982-04-20
JPS5455717A (en) 1979-05-04
ATA612478A (de) 1983-01-15
ZA784855B (en) 1980-04-30
DK618189A (da) 1989-12-07
IE781708L (en) 1979-02-25

Similar Documents

Publication Publication Date Title
BE869915A (fr) Procede de preparation de microspheres comportant un noyau solide et une matiere polymere
FR2484281B1 (fr) Procede de preparation de microspheres comportant un noyau solide et une matiere polymere
JPS53102733A (en) Production method of photographic material
GB2001447B (en) Developing material for electrophotography process for preparation thereof and image-forming method
DE3063368D1 (en) Polymers and process for their preparation
BE851548A (fr) Procede de preparation d'un support poreux solide et application
JPS5419810A (en) Pressureesensitive copying material and making method thereof
JPS5315905A (en) Method of making offset plate material
BE866383A (fr) Nouveau polymere et son procede de preparation
JPS5379601A (en) Method of forming halftome plate
JPS5299961A (en) Method of forming plate material by shottpeening
JPS5416203A (en) Dry making method of photosensitive resin plate
JPS5466986A (en) Method of making plateeshaped molding material
EP0029611A3 (en) Retroreflection plate and process for its production
JPS53123481A (en) Method for making heattresistant sounddabsorbent material
JPS5436045A (en) Method of making heattinsulating shape material
JPS5433329A (en) Foundation material and making method thereof
JPS541326A (en) Method of making noncombustible material
JPS5428311A (en) Method of making siccgraphite composite material
JPS53111719A (en) Method of forming material
JPS5329803A (en) Method of making printing plate material
JPS5436044A (en) Method of making heattinsulating shape material
JPS5338114A (en) Method of forming foundation for residence
JPS544322A (en) Method of producing positiveeactive material for solid electrolyte cell
JPS5424911A (en) Method of making hexagonal monocarbide solid solution material

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19860831