JPS5455717A - Minute globules and production - Google Patents

Minute globules and production

Info

Publication number
JPS5455717A
JPS5455717A JP10237078A JP10237078A JPS5455717A JP S5455717 A JPS5455717 A JP S5455717A JP 10237078 A JP10237078 A JP 10237078A JP 10237078 A JP10237078 A JP 10237078A JP S5455717 A JPS5455717 A JP S5455717A
Authority
JP
Japan
Prior art keywords
production
minute globules
globules
minute
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10237078A
Other languages
Japanese (ja)
Other versions
JPS645005B2 (en
Inventor
Uin Fuon Jiyoonzu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPS5455717A publication Critical patent/JPS5455717A/en
Publication of JPS645005B2 publication Critical patent/JPS645005B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/025—Explicitly spheroidal or spherical shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/624—Coated by macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/654—The particulate/core comprising macromolecular material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Dispersion Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
JP10237078A 1977-08-25 1978-08-24 Minute globules and production Granted JPS5455717A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82771077A 1977-08-25 1977-08-25

Publications (2)

Publication Number Publication Date
JPS5455717A true JPS5455717A (en) 1979-05-04
JPS645005B2 JPS645005B2 (en) 1989-01-27

Family

ID=25249947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10237078A Granted JPS5455717A (en) 1977-08-25 1978-08-24 Minute globules and production

Country Status (21)

Country Link
JP (1) JPS5455717A (en)
AT (1) AT372019B (en)
AU (1) AU522215B2 (en)
BE (1) BE869915A (en)
CA (1) CA1122077A (en)
CH (2) CH649217A5 (en)
DE (1) DE2836044A1 (en)
DK (2) DK361878A (en)
ES (1) ES472800A1 (en)
FI (1) FI64899C (en)
FR (1) FR2400950A1 (en)
GB (1) GB2003108B (en)
IE (1) IE47255B1 (en)
IL (1) IL55418A (en)
IT (1) IT1098111B (en)
NL (1) NL7808613A (en)
NZ (1) NZ188232A (en)
PH (1) PH15447A (en)
PT (1) PT68473A (en)
SE (1) SE431942B (en)
ZA (1) ZA784855B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57120515A (en) * 1980-11-29 1982-07-27 Sandoz Ag Medicinal composition
JPS5933214A (en) * 1982-08-19 1984-02-23 Mitsui Toatsu Chem Inc Carcinostatic agent formed to microsphere and its preparation
JPH02504025A (en) * 1987-05-01 1990-11-22 マサチューセッツ インスティテュート オブ テクノロジー Preparation of multiwalled polymeric microcapsules
JPH04312501A (en) * 1991-02-06 1992-11-04 Hoechst Ag New agent for protecting crop
WO2009142231A1 (en) * 2008-05-21 2009-11-26 東レ株式会社 Method for producing polymer fine particle
JP2011037882A (en) * 2001-08-31 2011-02-24 Alkermes Inc Method for extracting residual solvent and microparticle produced thereby
JP2011506077A (en) * 2007-12-11 2011-03-03 ナンヤン テクノロジカル ユニヴァーシティー Hollow multilayer microspheres for the delivery of hydrophilic active compounds
CN103828801A (en) * 2014-01-15 2014-06-04 福建农林大学 Spinosyn/emamectin benzoate microsphere and preparation method thereof

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045845B2 (en) * 1979-10-31 1985-10-12 田辺製薬株式会社 Method for producing microcapsules containing pharmaceutical substances
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
AT382076B (en) * 1982-10-15 1987-01-12 Chemie Linz Ag METHOD FOR THE PRODUCTION OF PRESSURES WITH RETARDED ACTIVE SUBSTANCE RELEASE
DE3417576A1 (en) * 1984-05-11 1985-11-14 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München RETARD FORMS OF ALPHA- (2,5-DIMETHOXY-PHENYL) -SS-GLYCINAMIDOAETHANOL AND METHOD FOR THE PRODUCTION THEREOF
DE3428372A1 (en) * 1984-08-01 1986-02-13 Hoechst Ag, 6230 Frankfurt CONTROLLED RELEASE REGULAR PEPTIDES MICROCAPSULES, PRODUCTION METHOD AND INJECTION PREPARATIONS
CH660302A5 (en) * 1984-10-17 1987-04-15 Debiopharm Sa HETEROGENEOUS PHASE MICRO-ENCAPSULATION PROCESS OF WATER-SOLUBLE DRUG SUBSTANCES.
CH669506A5 (en) * 1986-01-13 1989-03-31 Hugo Degen Oscillating and reclining furniture
DE3712095A1 (en) * 1987-04-10 1988-10-20 Lentia Gmbh BINDER-FREE GRANULES WITH DELAYED DELIVERY OF ACTIVE SUBSTANCES
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
FR2657255B1 (en) * 1989-12-27 1992-04-24 Sederma Sa DESCRIPTION OF ORIGINAL COSMETIC PREPARATIONS OF WHICH THE ACTIVE INGREDIENTS ARE TRAPPED IN A POLYMERIC NETWORK GRAFT ON THE SURFACE OF SILICA PARTICLES.
US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
US6787090B2 (en) 2000-05-12 2004-09-07 Matregen Corp. Method of producing structures using centrifugal forces
US6969480B2 (en) 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51125675A (en) * 1975-02-13 1976-11-02 Asahi Chem Ind Co Ltd A porous capsule structvre and a process for manufacturing turing it

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT631615A (en) * 1960-02-26
US3427250A (en) * 1963-03-25 1969-02-11 Polaroid Corp Microscopic capsules and process for their preparation
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
FR1497584A (en) * 1966-08-11 1967-10-13 Roussel Uclaf Microcapsule manufacturing process
US3703474A (en) * 1967-08-21 1972-11-21 Ncr Co Encapsulation process
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51125675A (en) * 1975-02-13 1976-11-02 Asahi Chem Ind Co Ltd A porous capsule structvre and a process for manufacturing turing it

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57120515A (en) * 1980-11-29 1982-07-27 Sandoz Ag Medicinal composition
JPS5933214A (en) * 1982-08-19 1984-02-23 Mitsui Toatsu Chem Inc Carcinostatic agent formed to microsphere and its preparation
JPH0363532B2 (en) * 1982-08-19 1991-10-01 Mitsui Toatsu Chemicals
JPH02504025A (en) * 1987-05-01 1990-11-22 マサチューセッツ インスティテュート オブ テクノロジー Preparation of multiwalled polymeric microcapsules
JPH04312501A (en) * 1991-02-06 1992-11-04 Hoechst Ag New agent for protecting crop
JP2013216676A (en) * 2001-08-31 2013-10-24 Alkermes Pharma Ireland Ltd Residual solvent extraction method, and microparticle prepared by the same
JP2011037882A (en) * 2001-08-31 2011-02-24 Alkermes Inc Method for extracting residual solvent and microparticle produced thereby
JP2015227383A (en) * 2001-08-31 2015-12-17 アルカームズ ファーマ アイルランド リミテッド Residual solvent extraction method and microparticles produced thereby
JP2011506077A (en) * 2007-12-11 2011-03-03 ナンヤン テクノロジカル ユニヴァーシティー Hollow multilayer microspheres for the delivery of hydrophilic active compounds
JP2012197461A (en) * 2008-05-21 2012-10-18 Toray Ind Inc Method for producing fine polymer particle
JP2012197460A (en) * 2008-05-21 2012-10-18 Toray Ind Inc Method for producing fine polymer particle
JP5099135B2 (en) * 2008-05-21 2012-12-12 東レ株式会社 Method for producing polymer fine particles
JP2013076085A (en) * 2008-05-21 2013-04-25 Toray Ind Inc Aromatic polyethersulfone particle
WO2009142231A1 (en) * 2008-05-21 2009-11-26 東レ株式会社 Method for producing polymer fine particle
US8574669B2 (en) 2008-05-21 2013-11-05 Toray Industries, Inc. Method for producing polymer fine particle comprising contacting an emulsion with a poor solvent
US9410004B2 (en) 2008-05-21 2016-08-09 Toray Industries, Inc. Aromatic polyethersulfone microparticles having narrow particle diameter distribution index
US10239970B2 (en) 2008-05-21 2019-03-26 Toray Industries, Inc. Method of producing fine particles of non-vinyl thermoplastic polymer
CN103828801A (en) * 2014-01-15 2014-06-04 福建农林大学 Spinosyn/emamectin benzoate microsphere and preparation method thereof

Also Published As

Publication number Publication date
SE431942B (en) 1984-03-12
AU3923678A (en) 1980-02-28
ZA784855B (en) 1980-04-30
IL55418A (en) 1981-07-31
DE2836044A1 (en) 1979-03-01
PT68473A (en) 1978-09-01
CA1122077A (en) 1982-04-20
FI782501A (en) 1979-02-26
DK618189D0 (en) 1989-12-07
DK618189A (en) 1989-12-07
FR2400950A1 (en) 1979-03-23
IT7826961A0 (en) 1978-08-23
CH644768A5 (en) 1984-08-31
AT372019B (en) 1983-08-25
IE47255B1 (en) 1984-02-08
AU522215B2 (en) 1982-05-20
NL7808613A (en) 1979-02-27
DE2836044C2 (en) 1988-06-23
GB2003108B (en) 1982-03-24
FR2400950B1 (en) 1983-10-07
BE869915A (en) 1979-02-23
IT1098111B (en) 1985-09-07
SE7808759L (en) 1979-02-26
CH649217A5 (en) 1985-05-15
GB2003108A (en) 1979-03-07
NZ188232A (en) 1980-12-19
FI64899B (en) 1983-10-31
ES472800A1 (en) 1979-10-16
JPS645005B2 (en) 1989-01-27
ATA612478A (en) 1983-01-15
FI64899C (en) 1984-02-10
IE781708L (en) 1979-02-25
IL55418A0 (en) 1978-10-31
DK361878A (en) 1979-02-26
PH15447A (en) 1983-01-18

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