IT7826961A0 - PROCESS FOR THE PRODUCTION OF MICROSPHERES AND MICROSPHERES SO OBTAINED. - Google Patents

PROCESS FOR THE PRODUCTION OF MICROSPHERES AND MICROSPHERES SO OBTAINED.

Info

Publication number
IT7826961A0
IT7826961A0 IT7826961A IT2696178A IT7826961A0 IT 7826961 A0 IT7826961 A0 IT 7826961A0 IT 7826961 A IT7826961 A IT 7826961A IT 2696178 A IT2696178 A IT 2696178A IT 7826961 A0 IT7826961 A0 IT 7826961A0
Authority
IT
Italy
Prior art keywords
microspheres
production
Prior art date
Application number
IT7826961A
Other languages
Italian (it)
Other versions
IT1098111B (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT7826961A0 publication Critical patent/IT7826961A0/en
Application granted granted Critical
Publication of IT1098111B publication Critical patent/IT1098111B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/025—Explicitly spheroidal or spherical shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/624—Coated by macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/654—The particulate/core comprising macromolecular material
IT26961/78A 1977-08-25 1978-08-23 PROCESS FOR THE PRODUCTION OF MICROSPHERES AND MICROSPHERES SO OBTAINED IT1098111B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82771077A 1977-08-25 1977-08-25

Publications (2)

Publication Number Publication Date
IT7826961A0 true IT7826961A0 (en) 1978-08-23
IT1098111B IT1098111B (en) 1985-09-07

Family

ID=25249947

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26961/78A IT1098111B (en) 1977-08-25 1978-08-23 PROCESS FOR THE PRODUCTION OF MICROSPHERES AND MICROSPHERES SO OBTAINED

Country Status (21)

Country Link
JP (1) JPS5455717A (en)
AT (1) AT372019B (en)
AU (1) AU522215B2 (en)
BE (1) BE869915A (en)
CA (1) CA1122077A (en)
CH (2) CH649217A5 (en)
DE (1) DE2836044A1 (en)
DK (2) DK361878A (en)
ES (1) ES472800A1 (en)
FI (1) FI64899C (en)
FR (1) FR2400950A1 (en)
GB (1) GB2003108B (en)
IE (1) IE47255B1 (en)
IL (1) IL55418A (en)
IT (1) IT1098111B (en)
NL (1) NL7808613A (en)
NZ (1) NZ188232A (en)
PH (1) PH15447A (en)
PT (1) PT68473A (en)
SE (1) SE431942B (en)
ZA (1) ZA784855B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045845B2 (en) * 1979-10-31 1985-10-12 田辺製薬株式会社 Method for producing microcapsules containing pharmaceutical substances
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
DE3045135A1 (en) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach BODEGRADABLE POLYMERS CONTAINING PHARMACEUTICAL COMPOSITIONS
JPS5933214A (en) * 1982-08-19 1984-02-23 Mitsui Toatsu Chem Inc Carcinostatic agent formed to microsphere and its preparation
AT382076B (en) * 1982-10-15 1987-01-12 Chemie Linz Ag METHOD FOR THE PRODUCTION OF PRESSURES WITH RETARDED ACTIVE SUBSTANCE RELEASE
DE3417576A1 (en) * 1984-05-11 1985-11-14 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München RETARD FORMS OF ALPHA- (2,5-DIMETHOXY-PHENYL) -SS-GLYCINAMIDOAETHANOL AND METHOD FOR THE PRODUCTION THEREOF
DE3428372A1 (en) * 1984-08-01 1986-02-13 Hoechst Ag, 6230 Frankfurt CONTROLLED RELEASE REGULAR PEPTIDES MICROCAPSULES, PRODUCTION METHOD AND INJECTION PREPARATIONS
CH660302A5 (en) * 1984-10-17 1987-04-15 Debiopharm Sa HETEROGENEOUS PHASE MICRO-ENCAPSULATION PROCESS OF WATER-SOLUBLE DRUG SUBSTANCES.
CH669506A5 (en) * 1986-01-13 1989-03-31 Hugo Degen Oscillating and reclining furniture
DE3712095A1 (en) * 1987-04-10 1988-10-20 Lentia Gmbh BINDER-FREE GRANULES WITH DELAYED DELIVERY OF ACTIVE SUBSTANCES
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
FR2657255B1 (en) * 1989-12-27 1992-04-24 Sederma Sa DESCRIPTION OF ORIGINAL COSMETIC PREPARATIONS OF WHICH THE ACTIVE INGREDIENTS ARE TRAPPED IN A POLYMERIC NETWORK GRAFT ON THE SURFACE OF SILICA PARTICLES.
DE4127757A1 (en) * 1991-02-06 1992-08-13 Hoechst Ag NEW PLANT PROTECTIVE FORMULATIONS
US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
US6969480B2 (en) 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces
ES2267764T3 (en) 2000-05-12 2007-03-16 Matregen Corp. METHOD TO PRODUCE STRUCTURES USING CENTRIFUGAL FORCES.
US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
EP2219775A4 (en) * 2007-12-11 2012-10-03 Univ Nanyang Tech Hollow multi-layered microspheres for delivery of hydrophilic active compounds
JP5099135B2 (en) * 2008-05-21 2012-12-12 東レ株式会社 Method for producing polymer fine particles
CN103828801B (en) * 2014-01-15 2016-01-27 福建农林大学 Pleocidin/emamectin-benzoate microballoon and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT631615A (en) * 1960-02-26
US3427250A (en) * 1963-03-25 1969-02-11 Polaroid Corp Microscopic capsules and process for their preparation
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
FR1497584A (en) * 1966-08-11 1967-10-13 Roussel Uclaf Microcapsule manufacturing process
US3703474A (en) * 1967-08-21 1972-11-21 Ncr Co Encapsulation process
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
JPS51125675A (en) * 1975-02-13 1976-11-02 Asahi Chem Ind Co Ltd A porous capsule structvre and a process for manufacturing turing it

Also Published As

Publication number Publication date
AU3923678A (en) 1980-02-28
PT68473A (en) 1978-09-01
DK618189A (en) 1989-12-07
AT372019B (en) 1983-08-25
SE431942B (en) 1984-03-12
FI64899B (en) 1983-10-31
IT1098111B (en) 1985-09-07
PH15447A (en) 1983-01-18
FI782501A (en) 1979-02-26
IE47255B1 (en) 1984-02-08
CH644768A5 (en) 1984-08-31
BE869915A (en) 1979-02-23
DK618189D0 (en) 1989-12-07
IL55418A (en) 1981-07-31
NL7808613A (en) 1979-02-27
IE781708L (en) 1979-02-25
JPS5455717A (en) 1979-05-04
SE7808759L (en) 1979-02-26
FR2400950A1 (en) 1979-03-23
NZ188232A (en) 1980-12-19
ATA612478A (en) 1983-01-15
ZA784855B (en) 1980-04-30
GB2003108A (en) 1979-03-07
DE2836044C2 (en) 1988-06-23
IL55418A0 (en) 1978-10-31
CA1122077A (en) 1982-04-20
GB2003108B (en) 1982-03-24
ES472800A1 (en) 1979-10-16
AU522215B2 (en) 1982-05-20
DE2836044A1 (en) 1979-03-01
JPS645005B2 (en) 1989-01-27
FR2400950B1 (en) 1983-10-07
DK361878A (en) 1979-02-26
CH649217A5 (en) 1985-05-15
FI64899C (en) 1984-02-10

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