BE862514A - Prostaglandines bicycliques et leur procede de preparation - Google Patents

Prostaglandines bicycliques et leur procede de preparation

Info

Publication number
BE862514A
BE862514A BE183997A BE183997A BE862514A BE 862514 A BE862514 A BE 862514A BE 183997 A BE183997 A BE 183997A BE 183997 A BE183997 A BE 183997A BE 862514 A BE862514 A BE 862514A
Authority
BE
Belgium
Prior art keywords
preparation process
prostaglandins
bicyclic
bicyclic prostaglandins
preparation
Prior art date
Application number
BE183997A
Other languages
English (en)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT3104176A external-priority patent/IT1072541B/it
Priority claimed from IT1928377A external-priority patent/IT1079103B/it
Priority claimed from IT2117177A external-priority patent/IT1085878B/it
Priority claimed from IT2141277A external-priority patent/IT1075678B/it
Priority claimed from IT2186377A external-priority patent/IT1115636B/it
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of BE862514A publication Critical patent/BE862514A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
BE183997A 1976-12-31 1977-12-30 Prostaglandines bicycliques et leur procede de preparation BE862514A (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT3104176A IT1072541B (it) 1976-12-31 1976-12-31 6(9)-ossido-prostenoici acidi
IT1928377A IT1079103B (it) 1977-01-14 1977-01-14 Derivati del 9-ossido-alo-prostanoico acido
IT2117177A IT1085878B (it) 1977-03-14 1977-03-14 Bicilicli ossiranici 15-cheto-prostenoici acidi
IT2141277A IT1075678B (it) 1977-03-21 1977-03-21 15-idrossi-bicicliche prostaglandine
IT2186377A IT1115636B (it) 1977-03-31 1977-03-31 13,14-deidro-bicicliche prostaglandine

Publications (1)

Publication Number Publication Date
BE862514A true BE862514A (fr) 1978-04-14

Family

ID=27517783

Family Applications (1)

Application Number Title Priority Date Filing Date
BE183997A BE862514A (fr) 1976-12-31 1977-12-30 Prostaglandines bicycliques et leur procede de preparation

Country Status (19)

Country Link
US (9) US4297368A (fr)
JP (1) JPS5384959A (fr)
BE (1) BE862514A (fr)
CH (1) CH636096A5 (fr)
DE (1) DE2757919A1 (fr)
DK (1) DK586077A (fr)
FI (1) FI71138C (fr)
FR (1) FR2376147A1 (fr)
GB (1) GB1599280A (fr)
GR (1) GR66057B (fr)
HU (1) HU182725B (fr)
IL (1) IL53630A0 (fr)
KE (1) KE3196A (fr)
MY (1) MY8200265A (fr)
NL (1) NL7714613A (fr)
NO (1) NO153689C (fr)
NZ (1) NZ185986A (fr)
SE (1) SE437268B (fr)
YU (1) YU316677A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2410652A2 (fr) * 1977-12-05 1979-06-29 Upjohn Co Analogues de 5,6-dihydro-prostacycline et leur preparation
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs
US4273718A (en) * 1979-07-05 1981-06-16 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-9-deoxy-6ε,9αepoxy-16,16-difluoro-19-hydroxy-PGF1
US4301079A (en) * 1979-07-05 1981-11-17 The Upjohn Company 19-Hydroxy-19-methyl-PGI1 compounds

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2
IL58384A0 (en) 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
DE2947526A1 (de) * 1978-11-29 1980-06-12 Ono Pharmaceutical Co Prostacyclin-analoge
US4235924A (en) 1979-06-07 1980-11-25 American Cyanamid Company Prostacyclin analogs of the 1 series and related analogs wherein the carboxylic acid function has been replaced
US4321203A (en) * 1979-07-05 1982-03-23 The Upjohn Company 19-Hydroxy-7a-homo-PGI1 compounds
US4328156A (en) * 1979-07-05 1982-05-04 The Upjohn Company 19-Hydroxy-19-methyl-7α-homo-PGI1 compounds
US4474966A (en) * 1980-03-03 1984-10-02 The Upjohn Company 19-Hydroxy-7a-homo-PGI1 and 19-hydroxy-19-methyl-7a-homo-PGI1 compounds
DE3035713A1 (de) * 1980-09-22 1982-04-29 F. Hoffmann-La Roche & Co. AG, 4002 Basel Prostacycline
EP0059307A1 (fr) 1981-02-26 1982-09-08 Grünenthal GmbH Préparation de composés 2-oxabicyclo(3,3.0)-octane et leurs dérivés
US4543353A (en) * 1981-11-27 1985-09-24 Farmitalia Carlo Erba S.P.A. Ester and amide derivatives of 13,14-didehydro prostaglandins
EP0108451A3 (fr) * 1982-11-05 1985-04-10 The Procter & Gamble Company Analogues de prostaglandines
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
US5153174A (en) * 1989-10-30 1992-10-06 Union Carbide Chemicals & Plastics Inc. Polymer mixtures useful in skin care
WO1999012899A1 (fr) * 1997-09-09 1999-03-18 The Procter & Gamble Company Procede de production d'analogues de prostaglandine f
JP4767842B2 (ja) * 2003-04-01 2011-09-07 セラヴァンス， インコーポレーテッド β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有するジアリールメチル化合物および関連化合物
ES2567328T3 (es) 2009-07-28 2016-04-21 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
EP2669279B1 (fr) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Composé bicyclique et utilisation associée à des fins médicales
ES2581852T3 (es) 2011-01-27 2016-09-07 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
US10899729B2 (en) 2016-06-30 2021-01-26 Ono Pharmaceutical Co.. Ltd. Method for producing bicyclic compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
DE2720998A1 (de) * 1976-05-11 1977-11-24 Wellcome Found Cyclische aether, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
MX4813E (es) * 1976-06-01 1982-10-19 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
US4125712A (en) * 1976-06-01 1978-11-14 The Upjohn Company Certain 5,6-dihydro-prostacyclin analogs
US4123441A (en) * 1976-09-22 1978-10-31 The Upjohn Company Enlarged-hetero-ring prostacyclin analogs
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
HU182583B (en) 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
GB2002363B (en) * 1977-08-03 1982-03-24 Upjohn Co Prostacyclin analogues
US4206127A (en) 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2410652A2 (fr) * 1977-12-05 1979-06-29 Upjohn Co Analogues de 5,6-dihydro-prostacycline et leur preparation
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs
US4273718A (en) * 1979-07-05 1981-06-16 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-9-deoxy-6ε,9αepoxy-16,16-difluoro-19-hydroxy-PGF1
US4301079A (en) * 1979-07-05 1981-11-17 The Upjohn Company 19-Hydroxy-19-methyl-PGI1 compounds

Also Published As

Publication number Publication date
KE3196A (en) 1982-04-02
FI71138B (fi) 1986-08-14
GR66057B (fr) 1981-01-14
US4277491A (en) 1981-07-07
YU316677A (en) 1984-02-29
GB1599280A (en) 1981-09-30
US4230721A (en) 1980-10-28
MY8200265A (en) 1982-12-31
NO153689B (no) 1986-01-27
US4271184A (en) 1981-06-02
FI71138C (fi) 1986-11-24
FR2376147B1 (fr) 1982-01-08
US4297368A (en) 1981-10-27
HU182725B (en) 1984-03-28
FR2376147A1 (fr) 1978-07-28
FI773757A (fi) 1978-07-01
NO153689C (no) 1986-05-07
US4262016A (en) 1981-04-14
NO774524L (no) 1978-07-03
SE7714948L (sv) 1978-07-02
CH636096A5 (de) 1983-05-13
NL7714613A (nl) 1978-07-04
JPS5384959A (en) 1978-07-26
SE437268B (sv) 1985-02-18
US4303670A (en) 1981-12-01
IL53630A0 (en) 1978-03-10
DE2757919A1 (de) 1978-07-13
DK586077A (da) 1978-07-01
US4250188A (en) 1981-02-10
NZ185986A (en) 1979-12-11
US4254137A (en) 1981-03-03
US4328240A (en) 1982-05-04

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: CARLO ERBA S.P.A.

Effective date: 19861231