IT1072541B - 6(9)-ossido-prostenoici acidi - Google Patents
6(9)-ossido-prostenoici acidiInfo
- Publication number
- IT1072541B IT1072541B IT3104176A IT3104176A IT1072541B IT 1072541 B IT1072541 B IT 1072541B IT 3104176 A IT3104176 A IT 3104176A IT 3104176 A IT3104176 A IT 3104176A IT 1072541 B IT1072541 B IT 1072541B
- Authority
- IT
- Italy
- Prior art keywords
- alkyl
- alkoxy
- antihypertensives
- oxido
- vasodilators
- Prior art date
Links
- 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title abstract 2
- 239000002220 antihypertensive agent Substances 0.000 title abstract 2
- 229940030600 antihypertensive agent Drugs 0.000 title abstract 2
- 229940124549 vasodilator Drugs 0.000 title abstract 2
- 239000003071 vasodilator agent Substances 0.000 title abstract 2
- 239000003705 antithrombocytic agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- -1 1H-tetrazol-5-yl Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 abstract 1
- PXGPLTODNUVGFL-BRIYLRKRSA-N (E,Z)-(1R,2R,3R,5S)-7-(3,5-Dihydroxy-2-((3S)-(3-hydroxy-1-octenyl))cyclopentyl)-5-heptenoic acid Chemical compound CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=CCCCC(O)=O PXGPLTODNUVGFL-BRIYLRKRSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 229960000711 alprostadil Drugs 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 239000000168 bronchodilator agent Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 abstract 1
- 229960002986 dinoprostone Drugs 0.000 abstract 1
- 125000002573 ethenylidene group Chemical group [*]=C=C([H])[H] 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000130 luteolytic agent Substances 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 239000002863 oxytocic agent Substances 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 abstract 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 abstract 1
- CBOMORHDRONZRN-QLOYDKTKSA-N prostaglandin E3 Chemical compound CC\C=C/C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O CBOMORHDRONZRN-QLOYDKTKSA-N 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002731 stomach secretion inhibitor Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (36)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3104176A IT1072541B (it) | 1976-12-31 | 1976-12-31 | 6(9)-ossido-prostenoici acidi |
| ZA00777401A ZA777401B (en) | 1976-12-31 | 1977-12-12 | Bicyclic prostaglandins and process for their preparation |
| FI773757A FI71138C (fi) | 1976-12-31 | 1977-12-13 | Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner |
| AU31642/77A AU525965B2 (en) | 1976-12-31 | 1977-12-15 | Bicyclic prostaglandin derivatives |
| NZ185986A NZ185986A (en) | 1976-12-31 | 1977-12-15 | 2-oxa-bicyclic prostag-landins and pharmaceutical compositions |
| IL53630A IL53630A0 (en) | 1976-12-31 | 1977-12-18 | Bicyclic prostaglandins and process for their preparation |
| GB53226/77A GB1599280A (en) | 1976-12-31 | 1977-12-21 | 5,9-or 6,9-epoxyprostaglandins |
| GR55028A GR66057B (it) | 1976-12-31 | 1977-12-22 | |
| DE19772757919 DE2757919A1 (de) | 1976-12-31 | 1977-12-24 | Bicyclische prostaglandine, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische oder veterinaer-zubereitung |
| JP15758977A JPS5384959A (en) | 1976-12-31 | 1977-12-28 | Bicyclic prostaglandin and method for its production |
| DK586077A DK586077A (da) | 1976-12-31 | 1977-12-29 | Bicykliske prostaglandiner samt fremgangsmaade til fremstilling deraf |
| NL7714613A NL7714613A (nl) | 1976-12-31 | 1977-12-30 | Werkwijze ter bereiding van bicyclische pros- taglandinen, alsmede farmaceutische en veteri- naire preparaten. |
| YU03166/77A YU316677A (en) | 1976-12-31 | 1977-12-30 | Process for obtaining bicyclic prostaglandin |
| FR7739879A FR2376147A1 (fr) | 1976-12-31 | 1977-12-30 | Prostaglandines bicycliques, utiles notamment comme anti-agglutinants des plaquettes sanguines et leur procede de preparation |
| HU77EA181A HU182725B (en) | 1976-12-31 | 1977-12-30 | Process for producing dihydric-prostacyclin-derivatives |
| BE183997A BE862514A (fr) | 1976-12-31 | 1977-12-30 | Prostaglandines bicycliques et leur procede de preparation |
| SE7714948A SE437268B (sv) | 1976-12-31 | 1977-12-30 | Forfarande for framstellning av 2-oxa-bicykliska prostaglandiner |
| NO774524A NO153689C (no) | 1976-12-31 | 1977-12-30 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive bicykliske prostaglandiner. |
| CH4978A CH636096A5 (de) | 1976-12-31 | 1978-01-03 | Bicyclische prostaglandine, verfahren zu ihrer herstellung und pharmazeutische praeparate. |
| US05/920,166 US4297368A (en) | 1976-12-31 | 1978-06-29 | Pharmaceutically useful 5,6-saturated PGI compounds |
| US05/928,809 US4328240A (en) | 1976-12-31 | 1978-07-28 | Certain PGI1 compounds and their pharmaceutical composition and methods |
| US05/965,267 US4277491A (en) | 1976-12-31 | 1978-12-01 | Bicyclic prostaglandins |
| US05/015,148 US4230721A (en) | 1976-12-31 | 1979-02-26 | Bicyclic prostaglandins |
| US06/029,925 US4303670A (en) | 1976-12-31 | 1979-04-13 | Bicyclic prostaglandins and process for their preparation |
| CA000329306A CA1183839A (en) | 1976-12-31 | 1979-06-08 | Bicyclic prostaglandins and process for their preparation |
| CA000329309A CA1183840A (en) | 1976-12-31 | 1979-06-08 | Bicyclic prostaglandins and process for their preparation |
| US06/049,118 US4254137A (en) | 1976-12-31 | 1979-06-18 | Bicyclic prostaglandins and process for their preparation |
| US06/049,326 US4262016A (en) | 1976-12-31 | 1979-06-18 | Bicyclic prostaglandins and process for their preparation |
| US06/090,305 US4250188A (en) | 1976-12-31 | 1979-11-01 | Certain PGI1 compounds and pharmaceutical compositions containing them |
| US06/098,963 US4271184A (en) | 1976-12-31 | 1979-11-30 | Bicyclic prostaglandins |
| AT764979A AT376430B (de) | 1976-12-31 | 1979-12-03 | Verfahren zur herstellung von neuen und bekannten bicyclischen prostaglandinen und deren salzen und isomeren |
| CA000366521A CA1183841A (en) | 1976-12-31 | 1980-12-10 | Bicyclic prostaglandins and process for their preparation |
| CA000394875A CA1183842A (en) | 1976-12-31 | 1982-01-25 | Bicyclic prostaglandins and process for their preparation |
| KE3196A KE3196A (en) | 1976-12-31 | 1982-03-17 | 5,9-or 6,9-epoxyprostaglandins |
| HK29082A HK29082A (en) | 1976-12-31 | 1982-06-30 | 5,9-or 6,9-epoxyprostaglandins |
| MY265/82A MY8200265A (en) | 1976-12-31 | 1982-12-30 | 5,9-or 6,9-epoxyprostaglandins |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3104176A IT1072541B (it) | 1976-12-31 | 1976-12-31 | 6(9)-ossido-prostenoici acidi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1072541B true IT1072541B (it) | 1985-04-10 |
Family
ID=11233005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT3104176A IT1072541B (it) | 1976-12-31 | 1976-12-31 | 6(9)-ossido-prostenoici acidi |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | IT1072541B (it) |
| ZA (1) | ZA777401B (it) |
-
1976
- 1976-12-31 IT IT3104176A patent/IT1072541B/it active
-
1977
- 1977-12-12 ZA ZA00777401A patent/ZA777401B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA777401B (en) | 1978-09-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES428889A1 (es) | Procedimiento de preparacion de derivados de acido prosta- noico. | |
| JPS5444639A (en) | Prostaglandin analog and its preparation | |
| FR2294696A1 (fr) | Nouveaux analogues de prostaglandines, leur procede de preparation et leurs applications | |
| ES436117A1 (es) | Procedimiento para la preparacion de nuevos compuestos ana- logos de acidos prostanoicos que no se presentan en la natu-raleza. | |
| ES420643A1 (es) | Procedimiento para la obtencion de sulfuros organicos. | |
| GB1488006A (en) | Prostaglandin analogues | |
| IT1072541B (it) | 6(9)-ossido-prostenoici acidi | |
| IT1085878B (it) | Bicilicli ossiranici 15-cheto-prostenoici acidi | |
| IT1115636B (it) | 13,14-deidro-bicicliche prostaglandine | |
| IT1079103B (it) | Derivati del 9-ossido-alo-prostanoico acido | |
| IT1075678B (it) | 15-idrossi-bicicliche prostaglandine | |
| GB1484591A (en) | Prostaglandin compositions | |
| GB1299136A (en) | Improvements in or relating to prostaglandins and the preparation thereof | |
| ES439322A1 (es) | Procedimiento para la preparacion de nuevos derivados de a- cido prostanoico. | |
| GB1458315A (en) | Prostanoic acid derivatives | |
| FR2399999A1 (fr) | Carbamates ou esters de derives du 4-prostene-1-ol et composition pharmaceutique ou veterinaire les contenant | |
| GB1486832A (en) | Prostanoic acid derivatives | |
| GB1496845A (en) | (dl)-13-substituted sulphinyl-prostaglandin-like compounds and methods of making | |
| GB1530154A (en) | Prostaglandin analogues | |
| FR2316925A1 (fr) | Dimethyl-16, 16 prostaglandines et procede de leur preparation | |
| ES443574A1 (es) | Procedimiento para la obtencion de derivados de ciclopenta- no. | |
| FR2013922A1 (en) | Prostaglandins | |
| FR2134673A1 (en) | Novel optically active isomers of prostaglandin analoguesof natural configuration useful as hypotensive agents, diuretics,contraceptives, for treating gastric ulcer and asthma, and forinhibiting platelet aggregation | |
| JPS5340742A (en) | Prostagilandin analogues, their preparation and medical composition containing the same as active constituents | |
| FR2157899A1 (en) | 16-mono and di-lower alkyl prostaglandin compsns - - for treatment of peptic ulcers |