FI773757A - Foerfarande foer framstaellning av bicykliska prostaglandiner - Google Patents

Foerfarande foer framstaellning av bicykliska prostaglandiner

Info

Publication number
FI773757A
FI773757A FI773757A FI773757A FI773757A FI 773757 A FI773757 A FI 773757A FI 773757 A FI773757 A FI 773757A FI 773757 A FI773757 A FI 773757A FI 773757 A FI773757 A FI 773757A
Authority
FI
Finland
Prior art keywords
prostaglandiner
bicycliska
foer faring
faring framstaellning
framstaellning
Prior art date
Application number
FI773757A
Other languages
English (en)
Other versions
FI71138C (fi
FI71138B (fi
Inventor
Carmelo Gandolfi
Carlo Passarotti
Alessandro Andreoni
Angelo Fumagalli
Franco Faustini
Roberto Ceserani
Maria Magdalena Usardi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT3104176A external-priority patent/IT1072541B/it
Priority claimed from IT1928377A external-priority patent/IT1079103B/it
Priority claimed from IT2117177A external-priority patent/IT1085878B/it
Priority claimed from IT2141277A external-priority patent/IT1075678B/it
Priority claimed from IT2186377A external-priority patent/IT1115636B/it
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI773757A publication Critical patent/FI773757A/fi
Application granted granted Critical
Publication of FI71138B publication Critical patent/FI71138B/fi
Publication of FI71138C publication Critical patent/FI71138C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI773757A 1976-12-31 1977-12-13 Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner FI71138C (fi)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
IT3104176A IT1072541B (it) 1976-12-31 1976-12-31 6(9)-ossido-prostenoici acidi
IT3104176 1976-12-31
IT1928377 1977-01-14
IT1928377A IT1079103B (it) 1977-01-14 1977-01-14 Derivati del 9-ossido-alo-prostanoico acido
IT2117177 1977-03-14
IT2117177A IT1085878B (it) 1977-03-14 1977-03-14 Bicilicli ossiranici 15-cheto-prostenoici acidi
IT2141277 1977-03-21
IT2141277A IT1075678B (it) 1977-03-21 1977-03-21 15-idrossi-bicicliche prostaglandine
IT2186377 1977-03-31
IT2186377A IT1115636B (it) 1977-03-31 1977-03-31 13,14-deidro-bicicliche prostaglandine

Publications (3)

Publication Number Publication Date
FI773757A true FI773757A (fi) 1978-07-01
FI71138B FI71138B (fi) 1986-08-14
FI71138C FI71138C (fi) 1986-11-24

Family

ID=27517783

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773757A FI71138C (fi) 1976-12-31 1977-12-13 Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner

Country Status (19)

Country Link
US (9) US4297368A (fi)
JP (1) JPS5384959A (fi)
BE (1) BE862514A (fi)
CH (1) CH636096A5 (fi)
DE (1) DE2757919A1 (fi)
DK (1) DK586077A (fi)
FI (1) FI71138C (fi)
FR (1) FR2376147A1 (fi)
GB (1) GB1599280A (fi)
GR (1) GR66057B (fi)
HU (1) HU182725B (fi)
IL (1) IL53630A0 (fi)
KE (1) KE3196A (fi)
MY (1) MY8200265A (fi)
NL (1) NL7714613A (fi)
NO (1) NO153689C (fi)
NZ (1) NZ185986A (fi)
SE (1) SE437268B (fi)
YU (1) YU316677A (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2
BE871209R (fr) * 1977-12-05 1979-04-12 Upjohn Co Analogues de 5,6-dihydro-prostacycline et leur preparation
IL58384A0 (en) 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
DE2947526A1 (de) * 1978-11-29 1980-06-12 Ono Pharmaceutical Co Prostacyclin-analoge
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs
US4235924A (en) 1979-06-07 1980-11-25 American Cyanamid Company Prostacyclin analogs of the 1 series and related analogs wherein the carboxylic acid function has been replaced
US4301079A (en) * 1979-07-05 1981-11-17 The Upjohn Company 19-Hydroxy-19-methyl-PGI1 compounds
US4321203A (en) * 1979-07-05 1982-03-23 The Upjohn Company 19-Hydroxy-7a-homo-PGI1 compounds
US4273718A (en) * 1979-07-05 1981-06-16 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-9-deoxy-6ε,9αepoxy-16,16-difluoro-19-hydroxy-PGF1
US4328156A (en) * 1979-07-05 1982-05-04 The Upjohn Company 19-Hydroxy-19-methyl-7α-homo-PGI1 compounds
US4474966A (en) * 1980-03-03 1984-10-02 The Upjohn Company 19-Hydroxy-7a-homo-PGI1 and 19-hydroxy-19-methyl-7a-homo-PGI1 compounds
DE3035713A1 (de) * 1980-09-22 1982-04-29 F. Hoffmann-La Roche & Co. AG, 4002 Basel Prostacycline
EP0059307A1 (de) 1981-02-26 1982-09-08 Grünenthal GmbH Verfahren zur Herstellung von 2-Oxabicyclo(3.3.0)octanderivaten und danach erhältliche Produkte
US4543353A (en) * 1981-11-27 1985-09-24 Farmitalia Carlo Erba S.P.A. Ester and amide derivatives of 13,14-didehydro prostaglandins
EP0108451A3 (en) * 1982-11-05 1985-04-10 The Procter & Gamble Company Novel prostaglandin analogues
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
US5153174A (en) * 1989-10-30 1992-10-06 Union Carbide Chemicals & Plastics Inc. Polymer mixtures useful in skin care
WO1999012899A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company A process for making prostaglandin f analogs
US7317102B2 (en) * 2003-04-01 2008-01-08 Theravance, Inc. Diarylmethyl and related compounds
JP5652397B2 (ja) 2009-07-28 2015-01-14 小野薬品工業株式会社 二環式化合物およびその医薬用途
JP5835236B2 (ja) 2011-01-27 2015-12-24 小野薬品工業株式会社 二環式化合物およびその医薬用途
JP5907077B2 (ja) 2011-01-27 2016-04-20 小野薬品工業株式会社 二環式化合物およびその医薬用途
JP6954282B2 (ja) 2016-06-30 2021-10-27 小野薬品工業株式会社 二環式化合物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
US4125712A (en) * 1976-06-01 1978-11-14 The Upjohn Company Certain 5,6-dihydro-prostacyclin analogs
MX4813E (es) * 1976-06-01 1982-10-19 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
US4123441A (en) * 1976-09-22 1978-10-31 The Upjohn Company Enlarged-hetero-ring prostacyclin analogs
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
HU182583B (en) 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
GB2002363B (en) * 1977-08-03 1982-03-24 Upjohn Co Prostacyclin analogues
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2

Also Published As

Publication number Publication date
DE2757919A1 (de) 1978-07-13
US4250188A (en) 1981-02-10
NO774524L (no) 1978-07-03
US4297368A (en) 1981-10-27
IL53630A0 (en) 1978-03-10
US4328240A (en) 1982-05-04
NL7714613A (nl) 1978-07-04
MY8200265A (en) 1982-12-31
HU182725B (en) 1984-03-28
CH636096A5 (de) 1983-05-13
KE3196A (en) 1982-04-02
FI71138C (fi) 1986-11-24
FR2376147A1 (fr) 1978-07-28
NO153689B (no) 1986-01-27
GB1599280A (en) 1981-09-30
FR2376147B1 (fi) 1982-01-08
US4271184A (en) 1981-06-02
US4230721A (en) 1980-10-28
YU316677A (en) 1984-02-29
DK586077A (da) 1978-07-01
US4277491A (en) 1981-07-07
US4254137A (en) 1981-03-03
SE7714948L (sv) 1978-07-01
GR66057B (fi) 1981-01-14
NO153689C (no) 1986-05-07
JPS5384959A (en) 1978-07-26
SE437268B (sv) 1985-02-18
FI71138B (fi) 1986-08-14
BE862514A (fr) 1978-04-14
US4303670A (en) 1981-12-01
NZ185986A (en) 1979-12-11
US4262016A (en) 1981-04-14

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A