BE844555A - Nouveaux derives de l'amino benzocycloheptene et leurs sels, procede de preparation et compositions pharmaceutiques - Google Patents
Nouveaux derives de l'amino benzocycloheptene et leurs sels, procede de preparation et compositions pharmaceutiquesInfo
- Publication number
- BE844555A BE844555A BE169272A BE169272A BE844555A BE 844555 A BE844555 A BE 844555A BE 169272 A BE169272 A BE 169272A BE 169272 A BE169272 A BE 169272A BE 844555 A BE844555 A BE 844555A
- Authority
- BE
- Belgium
- Prior art keywords
- benzocycloheptene
- salts
- amino
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
- C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7523499A FR2319332A1 (fr) | 1975-07-28 | 1975-07-28 | Nouveaux derives de l'aminobenzocycloheptene et leurs sels, procede de preparation et application a titre de medicaments desdits produits |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE844555A true BE844555A (fr) | 1977-01-27 |
Family
ID=9158434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE169272A BE844555A (fr) | 1975-07-28 | 1976-07-27 | Nouveaux derives de l'amino benzocycloheptene et leurs sels, procede de preparation et compositions pharmaceutiques |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4091115A (nl) |
| JP (1) | JPS5217455A (nl) |
| AT (1) | AT346303B (nl) |
| AU (1) | AU503674B2 (nl) |
| BE (1) | BE844555A (nl) |
| CA (1) | CA1088070A (nl) |
| CH (1) | CH616647A5 (nl) |
| DD (1) | DD126800A5 (nl) |
| DE (1) | DE2633889C2 (nl) |
| DK (1) | DK143105C (nl) |
| ES (2) | ES450166A1 (nl) |
| FI (1) | FI63014C (nl) |
| FR (1) | FR2319332A1 (nl) |
| GB (1) | GB1503119A (nl) |
| HU (1) | HU175289B (nl) |
| IE (1) | IE44014B1 (nl) |
| IL (1) | IL50116A (nl) |
| LU (1) | LU75470A1 (nl) |
| NL (1) | NL7608398A (nl) |
| PT (1) | PT65413B (nl) |
| SE (1) | SE7607944L (nl) |
| SU (1) | SU682121A3 (nl) |
| ZA (1) | ZA764546B (nl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2365339A1 (fr) * | 1976-09-23 | 1978-04-21 | Roussel Uclaf | Nouveaux derives de l'aminobenzocycloheptene, ainsi que leurs sels, procede de preparation et application a titre de medicaments de ces nouveaux produits |
| DK390477A (da) * | 1977-05-23 | 1978-11-24 | Sandoz Ag | Fremgangsmaade til fremstilling af cycloheptenderivater |
| FR2409256A1 (fr) * | 1977-11-18 | 1979-06-15 | Roussel Uclaf | Nouveaux derives de la 5h-benzocycloepten-7-amine et leurs sels, procede de preparation et application a titre de medicament |
| FR2633617B1 (fr) * | 1988-07-04 | 1991-02-08 | Adir | Nouveaux derives du benzocycloheptene, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| JPH051033A (ja) * | 1991-06-18 | 1993-01-08 | Tanabe Seiyaku Co Ltd | ベンゾシクロヘプテン誘導体及びその製法 |
| JP2003291819A (ja) * | 2002-03-29 | 2003-10-15 | Sanyo Electric Co Ltd | 台 車 |
| JP2007508314A (ja) * | 2003-10-08 | 2007-04-05 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | ピロバレロン類縁体及びそれらの治療的使用 |
| JP5513378B2 (ja) * | 2007-06-15 | 2014-06-04 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド | 治療化合物 |
| WO2009133052A1 (en) * | 2008-04-28 | 2009-11-05 | Janssen Pharmaceutica Nv | Benzocycloheptane and benzoxepine derivatives |
| US9024071B2 (en) | 2009-05-05 | 2015-05-05 | University Of Florida Research Foundation, Inc. | Therapeutic compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1202791B (de) * | 1960-09-19 | 1965-10-14 | Smith Kline French Lab | Verfahren zur Herstellung substituierter Cyclopropylamine |
| US3253037A (en) * | 1962-06-19 | 1966-05-24 | Ciba Geigy Corp | N-2-alkynyl-amino-benzocylo-alkanes |
| US3836534A (en) * | 1969-05-01 | 1974-09-17 | Colgate Palmolive Co | 5-piperazino-6-hydroxy-5h-benzo-cycloheptenes |
| US3751420A (en) * | 1971-04-01 | 1973-08-07 | Squibb & Sons Inc | Monoolmonoene amines |
-
1975
- 1975-07-28 FR FR7523499A patent/FR2319332A1/fr active Granted
-
1976
- 1976-07-02 HU HU76RO889A patent/HU175289B/hu unknown
- 1976-07-12 SE SE7607944A patent/SE7607944L/xx unknown
- 1976-07-21 CA CA257,474A patent/CA1088070A/fr not_active Expired
- 1976-07-23 FI FI762107A patent/FI63014C/fi not_active IP Right Cessation
- 1976-07-23 SU SU762382454A patent/SU682121A3/ru active
- 1976-07-23 IL IL50116A patent/IL50116A/xx unknown
- 1976-07-26 ES ES450166A patent/ES450166A1/es not_active Expired
- 1976-07-26 US US05/708,749 patent/US4091115A/en not_active Expired - Lifetime
- 1976-07-27 LU LU75470A patent/LU75470A1/xx unknown
- 1976-07-27 DD DD194089A patent/DD126800A5/xx unknown
- 1976-07-27 PT PT65413A patent/PT65413B/pt unknown
- 1976-07-27 AU AU16295/76A patent/AU503674B2/en not_active Expired
- 1976-07-27 BE BE169272A patent/BE844555A/xx not_active IP Right Cessation
- 1976-07-28 CH CH968376A patent/CH616647A5/fr not_active IP Right Cessation
- 1976-07-28 AT AT555776A patent/AT346303B/de not_active IP Right Cessation
- 1976-07-28 IE IE1671/76A patent/IE44014B1/en unknown
- 1976-07-28 DK DK338376A patent/DK143105C/da active
- 1976-07-28 GB GB31497/76A patent/GB1503119A/en not_active Expired
- 1976-07-28 NL NL7608398A patent/NL7608398A/nl not_active Application Discontinuation
- 1976-07-28 JP JP51089272A patent/JPS5217455A/ja active Pending
- 1976-07-28 DE DE2633889A patent/DE2633889C2/de not_active Expired
- 1976-07-28 ZA ZA764546A patent/ZA764546B/xx unknown
-
1977
- 1977-08-01 ES ES461268A patent/ES461268A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU175289B (hu) | 1980-06-28 |
| ES450166A1 (es) | 1977-11-16 |
| IL50116A (en) | 1979-10-31 |
| PT65413A (fr) | 1976-08-01 |
| SU682121A3 (ru) | 1979-08-25 |
| NL7608398A (nl) | 1977-02-01 |
| IE44014L (en) | 1977-01-28 |
| CH616647A5 (nl) | 1980-04-15 |
| ZA764546B (en) | 1977-09-28 |
| DK338376A (da) | 1977-01-29 |
| FI63014C (fi) | 1983-04-11 |
| PT65413B (fr) | 1978-06-09 |
| AU1629576A (en) | 1978-02-02 |
| AU503674B2 (en) | 1979-09-13 |
| FI762107A (nl) | 1977-01-29 |
| FR2319332B1 (nl) | 1978-11-17 |
| ES461268A1 (es) | 1978-08-16 |
| JPS5217455A (en) | 1977-02-09 |
| GB1503119A (en) | 1978-03-08 |
| IL50116A0 (en) | 1976-09-30 |
| SE7607944L (sv) | 1977-01-29 |
| US4091115A (en) | 1978-05-23 |
| ATA555776A (de) | 1978-03-15 |
| FI63014B (fi) | 1982-12-31 |
| LU75470A1 (nl) | 1977-04-06 |
| AT346303B (de) | 1978-11-10 |
| DK143105B (da) | 1981-03-30 |
| FR2319332A1 (fr) | 1977-02-25 |
| IE44014B1 (en) | 1981-07-29 |
| DE2633889A1 (de) | 1977-02-17 |
| DD126800A5 (nl) | 1977-08-10 |
| DE2633889C2 (de) | 1982-12-23 |
| DK143105C (da) | 1981-11-09 |
| CA1088070A (fr) | 1980-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: ROUSSEL-UCLAF Effective date: 19840727 |