BE844504A - Nouvelles guanidines, leur procede de preparation et leur applications - Google Patents
Nouvelles guanidines, leur procede de preparation et leur applicationsInfo
- Publication number
- BE844504A BE844504A BE169228A BE169228A BE844504A BE 844504 A BE844504 A BE 844504A BE 169228 A BE169228 A BE 169228A BE 169228 A BE169228 A BE 169228A BE 844504 A BE844504 A BE 844504A
- Authority
- BE
- Belgium
- Prior art keywords
- applications
- preparation process
- guanidines
- new
- new guanidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB31970/75A GB1564502A (en) | 1975-07-31 | 1975-07-31 | Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BE844504A true BE844504A (fr) | 1977-01-24 |
Family
ID=10331105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE169228A BE844504A (fr) | 1975-07-31 | 1976-07-23 | Nouvelles guanidines, leur procede de preparation et leur applications |
Country Status (31)
Country | Link |
---|---|
US (4) | US4083983A (xx) |
JP (2) | JPS5219671A (xx) |
AR (1) | AR213736A1 (xx) |
AT (1) | AT356132B (xx) |
AU (1) | AU502752B2 (xx) |
BE (1) | BE844504A (xx) |
BG (1) | BG27368A3 (xx) |
CA (1) | CA1068711A (xx) |
CH (1) | CH624938A5 (xx) |
CS (1) | CS189018B2 (xx) |
DD (1) | DD125204A5 (xx) |
DE (1) | DE2634433A1 (xx) |
DK (1) | DK316176A (xx) |
ES (1) | ES450310A1 (xx) |
FI (1) | FI762193A (xx) |
FR (1) | FR2319343A1 (xx) |
GB (1) | GB1564502A (xx) |
GR (1) | GR60810B (xx) |
HU (1) | HU173778B (xx) |
IE (1) | IE43508B1 (xx) |
IL (1) | IL50005A (xx) |
LU (1) | LU75507A1 (xx) |
NL (1) | NL7608496A (xx) |
NO (1) | NO762661L (xx) |
PH (1) | PH14555A (xx) |
PL (1) | PL103684B1 (xx) |
PT (1) | PT65348B (xx) |
SE (1) | SE7608477L (xx) |
SU (1) | SU692558A3 (xx) |
ZA (1) | ZA764082B (xx) |
ZM (1) | ZM9876A1 (xx) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4165378A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
US4165377A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidino imidazoles and thiazoles |
US4250316A (en) * | 1978-11-24 | 1981-02-10 | Bristol-Myers Company | Pyridyl guanidine anti-ulcer agents |
US4282363A (en) * | 1978-11-24 | 1981-08-04 | Bristol-Myers Company | 1-Nitro-2-(2-alkynylamino)-2-[(2-pyridylmethylthio)-ethylamino]ethylene derivatives |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4928863A (xx) * | 1972-07-13 | 1974-03-14 | ||
JPS5078968U (xx) * | 1973-11-20 | 1975-07-08 | ||
ZA774220B (en) * | 1976-07-28 | 1978-06-28 | Smith Kline French Lab | Pharmacologically active compounds |
US4233302A (en) * | 1977-12-23 | 1980-11-11 | Glaxo Group Limited | Amine derivatives and pharmaceutical compositions containing them |
NL8000869A (nl) * | 1979-02-16 | 1980-08-19 | Eisai Co Ltd | Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan. |
PT74865B (en) * | 1981-05-27 | 1983-12-07 | Smithkline Beckman Corp | Process of preparing a 2-(pyridylbutylamino)-pyrimidone and of its pharmaceutically acceptable salts |
SE8204879D0 (sv) * | 1982-08-26 | 1982-08-26 | Haessle Ab | Novel chemical intermediates |
DE3232462A1 (de) * | 1982-09-01 | 1984-03-01 | Bayer Ag, 5090 Leverkusen | 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
JPH0828166B2 (ja) * | 1985-01-16 | 1996-03-21 | 松下電器産業株式会社 | サ−モスタツト |
AU660132B2 (en) * | 1992-12-21 | 1995-06-08 | Bayer Aktiengesellschaft | Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridine |
US5380734A (en) * | 1993-04-15 | 1995-01-10 | American Home Products Corporation | N-cyanoamidine derivatives as anti-influenza agents |
EP3813900A4 (en) | 2018-06-29 | 2022-05-04 | 410 Medical, Inc. | SYSTEMS, DEVICE AND METHOD FOR FILTERING AIR FROM A FLUID LINE |
US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3968216A (en) * | 1969-10-29 | 1976-07-06 | Smith Kline & French Laboratories Limited | Method of inhibiting histamine activity with guanidine compounds |
US3808336A (en) | 1970-06-25 | 1974-04-30 | Smithkline Corp | Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives |
US3908014A (en) * | 1970-06-25 | 1975-09-23 | Smith Kline French Lab | Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives |
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
US3905984A (en) * | 1971-03-09 | 1975-09-16 | Smith Kline French Lab | Pyridyl substituted thioalkyl-and oxyalkyl-thioureas and ureas |
GB1397436A (en) * | 1972-09-05 | 1975-06-11 | Smith Kline French Lab | Heterocyclic n-cyanoguinidines |
US4002759A (en) * | 1973-05-17 | 1977-01-11 | Smith Kline & French Laboratories Limited | Pyridylbutylamino ethylene compounds |
GB1421792A (en) * | 1973-05-17 | 1976-01-21 | Smith Kline French Lab | Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them |
US4025527A (en) * | 1973-07-13 | 1977-05-24 | Smith Kline & French Laboratories Limited | Certain thiazoles and oxazoles |
GB1497260A (en) * | 1974-06-28 | 1978-01-05 | Smith Kline French Lab | Guanidine derivatives |
-
1975
- 1975-07-31 GB GB31970/75A patent/GB1564502A/en not_active Expired
-
1976
- 1976-07-09 ZA ZA764082A patent/ZA764082B/xx unknown
- 1976-07-09 PH PH18668A patent/PH14555A/en unknown
- 1976-07-09 IL IL50005A patent/IL50005A/xx unknown
- 1976-07-09 PT PT65348A patent/PT65348B/pt unknown
- 1976-07-13 US US05/704,877 patent/US4083983A/en not_active Expired - Lifetime
- 1976-07-13 DK DK316176A patent/DK316176A/da unknown
- 1976-07-21 CS CS764841A patent/CS189018B2/cs unknown
- 1976-07-22 CA CA257,590A patent/CA1068711A/en not_active Expired
- 1976-07-23 BE BE169228A patent/BE844504A/xx not_active IP Right Cessation
- 1976-07-23 ZM ZM98/76A patent/ZM9876A1/xx unknown
- 1976-07-27 GR GR51358A patent/GR60810B/el unknown
- 1976-07-27 AT AT552576A patent/AT356132B/de not_active IP Right Cessation
- 1976-07-27 SE SE7608477A patent/SE7608477L/xx not_active Application Discontinuation
- 1976-07-30 AU AU16453/76A patent/AU502752B2/en not_active Expired
- 1976-07-30 PL PL1976191537A patent/PL103684B1/pl unknown
- 1976-07-30 NL NL7608496A patent/NL7608496A/xx not_active Application Discontinuation
- 1976-07-30 DE DE19762634433 patent/DE2634433A1/de not_active Withdrawn
- 1976-07-30 DD DD194159A patent/DD125204A5/xx unknown
- 1976-07-30 FR FR7623453A patent/FR2319343A1/fr active Granted
- 1976-07-30 ES ES450310A patent/ES450310A1/es not_active Expired
- 1976-07-30 SU SU762386151A patent/SU692558A3/ru active
- 1976-07-30 BG BG7633887A patent/BG27368A3/xx unknown
- 1976-07-30 JP JP51092245A patent/JPS5219671A/ja active Pending
- 1976-07-30 IE IE1708/76A patent/IE43508B1/en unknown
- 1976-07-30 HU HU76SI1531A patent/HU173778B/hu unknown
- 1976-07-30 CH CH978576A patent/CH624938A5/de not_active IP Right Cessation
- 1976-07-30 LU LU75507A patent/LU75507A1/xx unknown
- 1976-07-30 FI FI762193A patent/FI762193A/fi not_active Application Discontinuation
- 1976-07-30 AR AR264159A patent/AR213736A1/es active
- 1976-07-30 NO NO762661A patent/NO762661L/no unknown
-
1979
- 1979-02-21 US US06/013,579 patent/US4215126A/en not_active Expired - Lifetime
- 1979-11-15 US US06/094,412 patent/US4264608A/en not_active Expired - Lifetime
-
1980
- 1980-11-19 US US06/208,370 patent/US4426526A/en not_active Expired - Lifetime
-
1985
- 1985-02-25 JP JP60037341A patent/JPS60243069A/ja active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4165378A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
US4165377A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidino imidazoles and thiazoles |
US4234735A (en) | 1977-04-20 | 1980-11-18 | Imperial Chemical Industries Limited | Guanidino imidazoles and thiazoles |
US4262126A (en) | 1977-04-20 | 1981-04-14 | Imperial Chemical Industries Limited | Guanidine derivatives of imidazoles and thiazoles |
US4250316A (en) * | 1978-11-24 | 1981-02-10 | Bristol-Myers Company | Pyridyl guanidine anti-ulcer agents |
US4282363A (en) * | 1978-11-24 | 1981-08-04 | Bristol-Myers Company | 1-Nitro-2-(2-alkynylamino)-2-[(2-pyridylmethylthio)-ethylamino]ethylene derivatives |
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: SMITH KLINE + FRENCH LABORATORIES LTD Effective date: 19840723 |