BE843839A - Nouvelles cyclobut-1-ene-3,4-diones substituees, leur procede de preparation et leurs applications - Google Patents

Nouvelles cyclobut-1-ene-3,4-diones substituees, leur procede de preparation et leurs applications

Info

Publication number
BE843839A
BE843839A BE168681A BE168681A BE843839A BE 843839 A BE843839 A BE 843839A BE 168681 A BE168681 A BE 168681A BE 168681 A BE168681 A BE 168681A BE 843839 A BE843839 A BE 843839A
Authority
BE
Belgium
Prior art keywords
cyclobut
diones
ene
substitutes
applications
Prior art date
Application number
BE168681A
Other languages
English (en)
Inventor
Ch R Ganellin
R Ch Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE843839A publication Critical patent/BE843839A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE168681A 1975-07-31 1976-07-06 Nouvelles cyclobut-1-ene-3,4-diones substituees, leur procede de preparation et leurs applications BE843839A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB31971/75A GB1563090A (en) 1975-07-31 1975-07-31 Cyclobutene-diones

Publications (1)

Publication Number Publication Date
BE843839A true BE843839A (fr) 1977-01-06

Family

ID=10331111

Family Applications (1)

Application Number Title Priority Date Filing Date
BE168681A BE843839A (fr) 1975-07-31 1976-07-06 Nouvelles cyclobut-1-ene-3,4-diones substituees, leur procede de preparation et leurs applications

Country Status (9)

Country Link
US (1) US4062863A (fr)
JP (1) JPS5219664A (fr)
AU (1) AU503067B2 (fr)
BE (1) BE843839A (fr)
DE (1) DE2634429A1 (fr)
FR (1) FR2319342A1 (fr)
GB (1) GB1563090A (fr)
IE (1) IE44124B1 (fr)
ZA (1) ZA763652B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165377A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidino imidazoles and thiazoles
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA792608B (en) * 1978-05-30 1980-06-25 Smith Kline French Lab Nitro compounds
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
EP0014057B1 (fr) * 1979-01-18 1985-01-02 Imperial Chemical Industries Plc Dérivés de la guanidine, procédés pour leur préparation et compositions pharmaceutiques les contenant
US4394508A (en) * 1980-06-07 1983-07-19 Bristol-Myers Company Chemical compounds
US4510309A (en) * 1981-03-03 1985-04-09 Bristol-Myers Company Histamine H2 -antagonists
US4526973A (en) * 1981-05-18 1985-07-02 Bristol-Myers Company Chemical compounds
US4395553A (en) * 1981-05-18 1983-07-26 Bristol-Myers Company Chemical compounds
US4539316A (en) * 1981-05-18 1985-09-03 Bristol-Myers Company Pyridine derivatives of 1,2-diaminocyclobutene-3,4-diones
US4522943A (en) * 1981-05-18 1985-06-11 Bristol-Myers Company Chemical compounds
US4390701A (en) * 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
US4788184A (en) * 1981-05-18 1988-11-29 Bristol-Myers Company Substituted 3-cyclobutene-1,2-diones as anti-ulcer agents
US4546188A (en) * 1981-05-18 1985-10-08 Bristol-Myers Company Substituted 1,2-diaminocyclobutene-3,4-diones
US4525477A (en) * 1981-12-02 1985-06-25 Smith Kline & French Laboratories Limited 2-Thiazolyl, isothiazolyl, oxazolyl and isoxazolyl alkylamino-3-nitro-heterocyclic compounds
JPS58190097A (ja) * 1982-04-30 1983-11-05 日本メクトロン株式会社 回路基板の製造法
FI832520L (fi) * 1982-07-12 1984-01-13 Bristol Myers Co Farmaceutiska foerfaranden och sammansaettningar
US4466970A (en) * 1982-10-02 1984-08-21 Smith Kline & French Laboratories Limited Dioxocyclobutene compounds
JO1279B1 (en) * 1982-12-23 1985-04-20 جون ايف روبرت Pyridine derivatives
DE3408327A1 (de) * 1984-03-07 1985-09-12 Ludwig Heumann & Co GmbH, 8500 Nürnberg Diaminderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS60255756A (ja) * 1984-06-01 1985-12-17 Ikeda Mohandou:Kk アミノアルキルフエノキシ誘導体
US4927968A (en) * 1987-05-14 1990-05-22 Bristol-Myers Company Chemical intermediates and process
US5168103A (en) * 1991-01-22 1992-12-01 American Home Products Corporation [[2-(amino-3,4-dioxo-1-cyclobuten-1-yl) amino]alkyl]-acid derivatives
CN111349014A (zh) * 2020-03-30 2020-06-30 绵阳达高特新材料有限公司 一种方酸甲胺甲酯的制备方法
WO2022034121A1 (fr) 2020-08-11 2022-02-17 Université De Strasbourg Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165377A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidino imidazoles and thiazoles
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
US4234735A (en) 1977-04-20 1980-11-18 Imperial Chemical Industries Limited Guanidino imidazoles and thiazoles
US4262126A (en) 1977-04-20 1981-04-14 Imperial Chemical Industries Limited Guanidine derivatives of imidazoles and thiazoles

Also Published As

Publication number Publication date
DE2634429A1 (de) 1977-02-10
AU1645176A (en) 1978-02-02
GB1563090A (en) 1980-03-19
FR2319342B1 (fr) 1978-11-17
AU503067B2 (en) 1979-08-23
US4062863A (en) 1977-12-13
ZA763652B (en) 1977-05-25
IE44124B1 (en) 1981-08-26
JPS5219664A (en) 1977-02-15
IE44124L (en) 1977-01-31
FR2319342A1 (fr) 1977-02-25

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITH KLINE + FRENCH LABORATORIES LTD

Effective date: 19840706