BE762135A - Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer - Google Patents

Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Info

Publication number
BE762135A
BE762135A BE762135A BE762135A BE762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A
Authority
BE
Belgium
Prior art keywords
thieno
pyrimidines
morpholino
news
manufacturing
Prior art date
Application number
BE762135A
Other languages
English (en)
French (fr)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of BE762135A publication Critical patent/BE762135A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE762135A 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer BE762135A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung

Publications (1)

Publication Number Publication Date
BE762135A true BE762135A (fr) 1971-07-27

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
BE762135A BE762135A (fr) 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Country Status (9)

Country Link
US (1) US3763156A (mo)
AU (1) AU2468871A (mo)
BE (1) BE762135A (mo)
ES (2) ES387554A1 (mo)
FR (1) FR2081464B1 (mo)
GB (1) GB1309182A (mo)
IL (1) IL36079A0 (mo)
NL (1) NL7101043A (mo)
NO (1) NO129205B (mo)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
EP2060575A1 (de) * 2006-04-19 2009-05-20 Boehringer Ingelheim International GmbH Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
CL2007001167A1 (es) 2006-04-26 2008-01-25 Genentech Inc Compuestos derivados de pirimidina condensada, inhibidores de p13-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicionfarmaceutica.
KR101402474B1 (ko) * 2006-04-26 2014-06-19 제넨테크, 인크. 포스포이노시티드 3-키나제 억제제 화합물 및 이를 포함하는 약학적 조성물
JP5148597B2 (ja) 2006-04-26 2013-02-20 エフ．ホフマン−ラ ロシュ アーゲー 医薬化合物
JP5284977B2 (ja) 2006-12-07 2013-09-11 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ホスホイノシチド３−キナーゼ阻害剤化合物及び使用方法
ES2571028T3 (es) * 2006-12-07 2016-05-23 Genentech Inc Compuestos inhibidores de fosfoinositida 3-cinasa y métodos de uso
ES2399774T3 (es) 2007-09-24 2013-04-03 Genentech, Inc. Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
BRPI0817781A2 (pt) 2007-10-19 2019-09-24 Boehringer Ingelheim Int piperazino-diidroteinopirimidinas substituídas com heterociclo
EP2215093B1 (de) 2007-10-19 2011-12-14 Boehringer Ingelheim International GmbH Neue piperazino-dihydrothienopyrimidin-derivate
ES2524910T3 (es) * 2007-10-19 2014-12-15 Boehringer Ingelheim International Gmbh Piperidino-dihidrotienopirimidinas sustituidas
CN101909631B (zh) * 2007-10-25 2012-09-12 健泰科生物技术公司 制备噻吩并嘧啶化合物的方法
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
EP2405916B1 (en) 2009-03-12 2018-02-07 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
EP2435438A1 (en) 2009-05-27 2012-04-04 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
CA2772371A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
ES2609767T3 (es) * 2009-10-12 2017-04-24 F. Hoffmann-La Roche Ag Combinaciones de un inhibidor de PI3K y un inhibidor de MEK
JP2013528787A (ja) 2010-04-16 2013-07-11 ジェネンテック， インコーポレイテッド Ｐｉ３ｋ／ａｋｔキナーゼ経路インヒビターの効果の予測バイオマーカーとしてのｆｏｘ０３ａ
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
CA2901126C (en) 2013-02-25 2022-01-25 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant
BR112021005914A2 (pt) * 2018-10-01 2021-06-29 Genzyme Corporation derivados de tieno[3,2-b]piridina como inibidores de udp glicosiltransferase e métodos de uso
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
AU2468871A (en) 1972-07-27
US3763156A (en) 1973-10-02
ES387554A1 (es) 1974-01-16
NL7101043A (mo) 1971-07-30
IL36079A0 (en) 1971-03-24
FR2081464B1 (mo) 1975-04-18
GB1309182A (en) 1973-03-07
ES387553A1 (es) 1974-01-16
FR2081464A1 (mo) 1971-12-03
NO129205B (mo) 1974-03-11

Similar Documents

Publication Publication Date Title
BE762135A (fr) Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer
BE779203A (fr) 2-hydrocarbyldithio-5-mercapto-1, 3, 4, -thiadiazoles et procede pour les preparer,
CH550476A (fr) Element dielectrique et procede pour le fabriquer.
BE783044A (fr) Nouvelles thieno(3,2-d) pyrimidines
BE759493A (fr) Nouvelles 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines et procedes pour les fabriquer
BE768898A (fr) Procede d'ajustement de capacites
BE776958R (fr) Tetra-oxo-1,2-dipiperazino-alcanes et procede pour leur
BE761232A (fr) Electrodes pour elements au ni-cd et procede de leur fabrication
BE776969A (fr) Nouvelles phenoxyalcoylamines, leur procede de preparation et leurs applications
BE761321A (fr) Nouvelles amines et procede pour leur preparation
BE770531A (fr) 3-formyl-cephalosporines et procede pour les preparer
BE768403A (fr) Nouvelles aminophenylamidines vermifuges et procede pour leur obtentio
IT953448B (it) Metodo per produrre seleniuri di arsenico e selenio drogato con arsenico
OA03675A (fr) Eléments de fondation et/ou de soutènement et procédé pour les fabriquer.
BE808599A (fr) Nouvelles pyrazolodiazepines et procede pour les preparer
BE746576A (fr) Ethers de 4.20.22-bufatrienolidrhamnoside et procede pour les preparer
BE748770A (fr) Nouveaux ethers basiques et procede pour les
BG19597A3 (bg) Метод за получаване на перидо/ 3,2-д/ пиримидини
BE761445A (fr) Procede de fabrication de telomeres et telomeres obtenus
BE794532A (fr) Nouvelles 3-hydroxymethyl-5-benzylidene-azolidinones et procede pour les fabriquer
BE752984A (fr) Procede de fabrication de la tetrachloropyrimidine
BE755689A (fr) Procede de fabrication de nouvelles 7 beta-alkyl-19- nortestosterones
BE753901A (fr) Nouvelles benzamidines et procede pour leur preparation
BE777238A (fr) Dioxypiperidines substituees et procede pour les
BE800564A (fr) Nouvelles 3,6-bis-(aminoacylamino)-acridines et procede pour les fabriquer