BE762135A - Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer - Google Patents

Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Info

Publication number
BE762135A
BE762135A BE762135A BE762135A BE762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A
Authority
BE
Belgium
Prior art keywords
thieno
pyrimidines
morpholino
news
manufacturing
Prior art date
Application number
BE762135A
Other languages
English (en)
French (fr)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of BE762135A publication Critical patent/BE762135A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE762135A 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer BE762135A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen

Publications (1)

Publication Number Publication Date
BE762135A true BE762135A (fr) 1971-07-27

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
BE762135A BE762135A (fr) 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Country Status (9)

Country Link
US (1) US3763156A (enFirst)
AU (1) AU2468871A (enFirst)
BE (1) BE762135A (enFirst)
ES (2) ES387554A1 (enFirst)
FR (1) FR2081464B1 (enFirst)
GB (1) GB1309182A (enFirst)
IL (1) IL36079A0 (enFirst)
NL (1) NL7101043A (enFirst)
NO (1) NO129205B (enFirst)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
JP5021624B2 (ja) * 2005-04-21 2012-09-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 炎症性疾患の治療用新規化合物
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
WO2007127183A1 (en) * 2006-04-26 2007-11-08 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
TWI409268B (zh) 2006-04-26 2013-09-21 Hoffmann La Roche 醫藥化合物
EP2041139B1 (en) 2006-04-26 2011-11-09 F. Hoffmann-La Roche AG Pharmaceutical compounds
PE20081353A1 (es) * 2006-12-07 2008-11-12 Hoffmann La Roche Compuestos del inhibidor de fosfoinositida 3-cinasa
JP5284977B2 (ja) * 2006-12-07 2013-09-11 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ホスホイノシチド３−キナーゼ阻害剤化合物及び使用方法
WO2009042607A1 (en) 2007-09-24 2009-04-02 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
CN101827853A (zh) 2007-10-19 2010-09-08 贝林格尔.英格海姆国际有限公司 杂环取代的哌嗪子基-二氢噻吩并嘧啶
ATE537175T1 (de) 2007-10-19 2011-12-15 Boehringer Ingelheim Int Neue piperazino-dihydrothienopyrimidin-derivate
KR101548975B1 (ko) * 2007-10-19 2015-09-01 베링거 인겔하임 인터내셔날 게엠베하 치환된 피페리디노-디하이드로티에노피리미딘
ES2439705T3 (es) 2007-10-25 2014-01-24 Genentech, Inc. Proceso para la preparación de compuestos de tienopirimidina
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
BRPI1006189A2 (pt) 2009-03-12 2020-08-18 Genentech Inc uso de uma combinação terapêutica, formulação farmacêutica, artigo de manufatura, produto, método para determinar compostos a serem utilizados em combinação para o tratamento de uma malignidade hematopoiética e método para selecionar compostos a serem utilizados em combinação para o tratamento de câncer
BRPI1009022A2 (pt) 2009-05-27 2016-03-08 Hoffmann La Roche "composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"
SG182247A1 (en) * 2009-05-27 2012-08-30 Hoffmann La Roche Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
MA33974B1 (fr) * 2009-10-12 2013-02-01 Hoffmann La Roche Combinaisons d'un inhibiteur de pi3k et d'un inhibiteur de mek
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
KR102182488B1 (ko) 2013-02-25 2020-11-24 제넨테크, 인크. 약물 내성 akt 돌연변이체의 검출 및 치료를 위한 방법 및 조성물
CN113423711B (zh) * 2018-10-01 2024-03-15 建新公司 作为udp糖基转移酶抑制剂的噻吩并[3,2-b]吡啶衍生物及其使用方法
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
FR2081464B1 (enFirst) 1975-04-18
AU2468871A (en) 1972-07-27
US3763156A (en) 1973-10-02
GB1309182A (en) 1973-03-07
ES387554A1 (es) 1974-01-16
FR2081464A1 (enFirst) 1971-12-03
ES387553A1 (es) 1974-01-16
NO129205B (enFirst) 1974-03-11
NL7101043A (enFirst) 1971-07-30
IL36079A0 (en) 1971-03-24

Similar Documents

Publication Publication Date Title
BE762135A (fr) Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer
BE779203A (fr) 2-hydrocarbyldithio-5-mercapto-1, 3, 4, -thiadiazoles et procede pour les preparer,
CH550476A (fr) Element dielectrique et procede pour le fabriquer.
BE783044A (fr) Nouvelles thieno(3,2-d) pyrimidines
BE759493A (fr) Nouvelles 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines et procedes pour les fabriquer
BE768898A (fr) Procede d'ajustement de capacites
BE761232A (fr) Electrodes pour elements au ni-cd et procede de leur fabrication
BE776969A (fr) Nouvelles phenoxyalcoylamines, leur procede de preparation et leurs applications
BE761321A (fr) Nouvelles amines et procede pour leur preparation
BE770531A (fr) 3-formyl-cephalosporines et procede pour les preparer
BE768403A (fr) Nouvelles aminophenylamidines vermifuges et procede pour leur obtentio
IT953448B (it) Metodo per produrre seleniuri di arsenico e selenio drogato con arsenico
OA03675A (fr) Eléments de fondation et/ou de soutènement et procédé pour les fabriquer.
BE808599A (fr) Nouvelles pyrazolodiazepines et procede pour les preparer
BE746576A (fr) Ethers de 4.20.22-bufatrienolidrhamnoside et procede pour les preparer
BE748770A (fr) Nouveaux ethers basiques et procede pour les
BG19597A3 (bg) Метод за получаване на перидо/ 3,2-д/ пиримидини
BE794532A (fr) Nouvelles 3-hydroxymethyl-5-benzylidene-azolidinones et procede pour les fabriquer
BE752984A (fr) Procede de fabrication de la tetrachloropyrimidine
BE755689A (fr) Procede de fabrication de nouvelles 7 beta-alkyl-19- nortestosterones
BE758621A (fr) Nouvelles amidines et leur procede de preparation
BE753901A (fr) Nouvelles benzamidines et procede pour leur preparation
BE777238A (fr) Dioxypiperidines substituees et procede pour les
BE800564A (fr) Nouvelles 3,6-bis-(aminoacylamino)-acridines et procede pour les fabriquer
BE750725A (fr) Nouvelles 2-alcoyloxymethyl-3-chloro-1, 2,4-thiaimidazol-5-oneset procede pour les preparer