BE2014C028I2 - - Google Patents

Info

Publication number
BE2014C028I2
BE2014C028I2 BE2014C028C BE2014C028C BE2014C028I2 BE 2014C028 I2 BE2014C028 I2 BE 2014C028I2 BE 2014C028 C BE2014C028 C BE 2014C028C BE 2014C028 C BE2014C028 C BE 2014C028C BE 2014C028 I2 BE2014C028 I2 BE 2014C028I2
Authority
BE
Belgium
Prior art keywords
treatment
tumors
bone
radium
bones
Prior art date
Application number
BE2014C028C
Other languages
English (en)
French (fr)
Original Assignee
Bayer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer As filed Critical Bayer As
Publication of BE2014C028I2 publication Critical patent/BE2014C028I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Radiation-Therapy Devices (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Compounds Of Unknown Constitution (AREA)
BE2014C028C 1999-01-04 2014-05-07 BE2014C028I2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
PCT/NO1999/000392 WO2000040275A2 (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning

Publications (1)

Publication Number Publication Date
BE2014C028I2 true BE2014C028I2 (de) 2019-03-05

Family

ID=19902803

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2014C028C BE2014C028I2 (de) 1999-01-04 2014-05-07

Country Status (25)

Country Link
US (2) US6635234B1 (de)
EP (1) EP1140212B1 (de)
JP (2) JP4649044B2 (de)
KR (1) KR100671387B1 (de)
CN (2) CN1194764C (de)
AT (1) ATE331534T1 (de)
AU (1) AU774991B2 (de)
BE (1) BE2014C028I2 (de)
BR (1) BR9916768A (de)
CA (1) CA2358498C (de)
CY (2) CY1105634T1 (de)
DE (1) DE69932183T2 (de)
DK (1) DK1140212T3 (de)
EA (1) EA003496B1 (de)
ES (1) ES2268888T3 (de)
HK (1) HK1090750A1 (de)
IL (1) IL144135A0 (de)
LU (1) LU92425I2 (de)
MX (1) MXPA01006823A (de)
NO (2) NO310544B1 (de)
NZ (3) NZ534618A (de)
PT (1) PT1140212E (de)
TR (3) TR200201440T2 (de)
WO (1) WO2000040275A2 (de)
ZA (1) ZA200105431B (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO313180B1 (no) 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
AUPQ923100A0 (en) * 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
WO2003061566A2 (en) * 2002-01-24 2003-07-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Anti-cancer combination and use thereof
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
EP2060274B1 (de) * 2003-04-30 2014-03-26 Ramot at Tel-Aviv University Ltd. Verfahren und Vorrichtung für Strahlentherapie
EP1735013B1 (de) * 2004-02-20 2012-02-08 Algeta ASA Alpha- und beta-emittierende hydroxyapatit-teilchen
DE102004022200B4 (de) * 2004-05-05 2006-07-20 Actinium Pharmaceuticals, Inc. Radium-Target sowie Verfahren zu seiner Herstellung
US7914766B1 (en) * 2004-06-03 2011-03-29 Ut-Battelle Llc Inorganic resins for clinical use of 213Bi generators
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
CA2615589A1 (en) * 2005-07-26 2007-02-01 Ramot At Tel Aviv University Ltd. A radioactive surface source and a method for producing the same
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
DE102006008023B4 (de) 2006-02-21 2008-05-29 Actinium Pharmaceuticals, Inc. Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets
ES2504522T3 (es) * 2006-09-08 2014-10-08 Actinium Pharmaceuticals Inc. Método para la purificación de radio a partir de diferentes fuentes
EP2116539A1 (de) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-Aryl-3-Amino-alkoxy-pyrazole als Sigma-Liganden zur Verbesserung der analgetischen Wirkung von Opioiden und zur Schwächung der Abhängigkeit davon
EP2353598A1 (de) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma-Liganden zur Anwendung in der Vorbeugung und/oder Behandlung von postoperativem Schmerz
EP2353591A1 (de) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma-Liganden zur Verstärkung der analgesischen Wirkung von Opioden und Opiaten bei postoperativem Schmerz und zur Schwächung der Abhängigkeit davon
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201007353D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
GB201007354D0 (en) 2010-04-30 2010-06-16 Algeta Asa Method
EP2388005A1 (de) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma-Liganden zur Vorbeugung und/oder Behandlung von Erbrechen infolge von Chemotherapie oder Strahlentherapie
EP2415471A1 (de) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Verwendung von Sigmaliganden bei opioidinduzierter Hyperalgesie
EP2524694A1 (de) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Verwendung von Sigmaliganden bei Schmerz im Zusammenhang mit Typ-2-Diabetes
EP2934545A1 (de) 2012-12-19 2015-10-28 Bayer Pharma Aktiengesellschaft Kombination aus radium-223 zur behandlung von krebs
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
EP3077003A1 (de) 2013-12-03 2016-10-12 Bayer Pharma Aktiengesellschaft Kombination von pi3k-inhibitoren
EP3077002B1 (de) 2013-12-03 2020-04-22 Bayer Pharma Aktiengesellschaft Kombination von pi3k-inhibitoren
CA2933511A1 (en) 2013-12-17 2015-06-25 Laboratorios Del Dr. Esteve, S.A. Serotonin-norepinephrine reuptake inhibitors (snris) and sigma receptor ligands combinations
WO2016083739A1 (fr) 2014-11-26 2016-06-02 Rhodia Operations Composition de lanthane et d'actinium-227
GB201600153D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
GB201600154D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
CZ2016821A3 (cs) * 2016-12-22 2018-07-04 České vysoké učení technické v Praze Kombinace pro radionuklidovou terapii pro použití jako léčivo
WO2018153969A1 (en) 2017-02-24 2018-08-30 Bayer Aktiengesellschaft Combination of atr kinase inhibitors with radium-223 salt
MX2019013346A (es) 2017-05-11 2020-01-20 Alpha Tau Medical Ltd Recubrimientos polimericos para dispositivos de braquiterapia.
JP2021519126A (ja) 2018-04-02 2021-08-10 アルファ タウ メディカル リミテッド 放射性核種の管理された放出
EP3563875A1 (de) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Radium für radionuklidtherapie, zusammen mit calciummetabolisme- beeinflüssender therapie
FR3086186B1 (fr) * 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
FR3088769B1 (fr) * 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
US20220152228A1 (en) * 2019-03-01 2022-05-19 Washington University Compositions and methods for radiotherapy using chelated radiotherapeutic agents and non-target tissue blockade
RU2752845C1 (ru) * 2020-05-13 2021-08-11 Акционерное Общество "Наука И Инновации" Способ получения высокочистого радия-223
AU2021400142A1 (en) 2020-12-16 2023-06-22 Alpha Tau Medical Ltd. Diffusing alpha-emitters radiation therapy with enhanced beta treatment
CN113066598B (zh) * 2021-03-25 2023-08-08 中国科学院近代物理研究所 一种从高能质子束辐照232Th靶引起的散裂反应中分离纯化223Ra的方法
US11964168B2 (en) 2021-06-10 2024-04-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for prostate cancer
WO2023159229A1 (en) 2022-02-21 2023-08-24 Bayer Healthcare Llc System, method and device for delivery of a therapeutic or diagnostic agent
WO2023159230A1 (en) 2022-02-21 2023-08-24 Bayer Healthcare Llc System, method and device for delivery of a therapeutic or diagnostic agent
CN115869658A (zh) * 2022-12-29 2023-03-31 中国核动力研究设计院 用于制备Ra-223的分离系统及其分离方法、应用和制备方法

Family Cites Families (14)

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CH668489A5 (de) * 1982-01-22 1988-12-30 Vnii Mineralnogo Syrya Radiometrisches verfahren zur bestimmung der konzentration natuerlicher radiumisotope und einrichtung zur durchfuehrung des verfahrens.
US5362473A (en) * 1988-10-14 1994-11-08 Mallinckrodt Medical, Inc. Radiolabelled particulate composition
US4970062A (en) * 1989-05-30 1990-11-13 The United States Of America As Represented By The United States Department Of Energy Colloid labelled with radionuclide and method
JPH07501332A (ja) * 1991-11-14 1995-02-09 バッテル・メモリアル・インスティチュート 癌を診断および治療する方法
WO1994026297A1 (en) * 1993-05-17 1994-11-24 Immunomedics, Inc. Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates
US5809394A (en) * 1996-12-13 1998-09-15 Battelle Memorial Institute Methods of separating short half-life radionuclides from a mixture of radionuclides
US6117413A (en) * 1997-11-12 2000-09-12 Battelle Memorial Institute Radionuclide-binding compound, a radionuclide delivery system, a method of making a radium complexing compound, a method of extracting a radionuclide, and a method of delivering a radionuclide
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
US20060228297A1 (en) * 2003-04-15 2006-10-12 Roy Larsen Thorium-227 for use in radiotherapy of soft tissue disease
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy

Also Published As

Publication number Publication date
HK1090750A1 (en) 2006-12-29
ES2268888T3 (es) 2007-03-16
NZ534618A (en) 2006-03-31
NO310544B1 (no) 2001-07-23
AU1700400A (en) 2000-07-24
BR9916768A (pt) 2001-12-04
KR20010092772A (ko) 2001-10-26
JP2010168397A (ja) 2010-08-05
NZ545023A (en) 2007-08-31
EA200100642A1 (ru) 2002-02-28
CN1194764C (zh) 2005-03-30
DE69932183D1 (de) 2006-08-10
NO990001L (no) 2000-07-05
EA003496B1 (ru) 2003-06-26
NO2014010I2 (de) 2014-05-09
EP1140212B1 (de) 2006-06-28
CA2358498A1 (en) 2000-07-13
TR200201442T2 (tr) 2002-08-21
CY2014020I2 (el) 2015-12-09
CA2358498C (en) 2008-09-16
IL144135A0 (en) 2002-05-23
ATE331534T1 (de) 2006-07-15
NO2014010I1 (no) 2014-06-02
CN1767078B (zh) 2012-01-11
WO2000040275A2 (en) 2000-07-13
LU92425I2 (fr) 2014-06-10
NZ513135A (en) 2004-09-24
MXPA01006823A (es) 2003-07-14
CN1335779A (zh) 2002-02-13
US6635234B1 (en) 2003-10-21
CN1767078A (zh) 2006-05-03
PT1140212E (pt) 2006-11-30
DE69932183T2 (de) 2007-05-16
JP5433490B2 (ja) 2014-03-05
JP2002534399A (ja) 2002-10-15
US20030206857A1 (en) 2003-11-06
TR200201440T2 (tr) 2002-08-21
EP1140212A2 (de) 2001-10-10
CY1105634T1 (el) 2010-12-22
WO2000040275A3 (en) 2001-06-21
DK1140212T3 (da) 2006-10-09
CY2014020I1 (el) 2015-12-09
KR100671387B1 (ko) 2007-01-19
ZA200105431B (en) 2002-07-02
NO990001D0 (no) 1999-01-04
JP4649044B2 (ja) 2011-03-09
TR200102707T2 (tr) 2002-03-21
AU774991B2 (en) 2004-07-15

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