BE1023340B1 - Composes - Google Patents
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- BE1023340B1 BE1023340B1 BE2015/5741A BE201505741A BE1023340B1 BE 1023340 B1 BE1023340 B1 BE 1023340B1 BE 2015/5741 A BE2015/5741 A BE 2015/5741A BE 201505741 A BE201505741 A BE 201505741A BE 1023340 B1 BE1023340 B1 BE 1023340B1
- Authority
- BE
- Belgium
- Prior art keywords
- compound
- pharmaceutically acceptable
- compounds
- formula
- composition
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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| US201462079027P | 2014-11-13 | 2014-11-13 | |
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| BR112017009648A2 (pt) * | 2014-11-13 | 2017-12-19 | Glaxosmithkline Biologicals Sa | composto, métodos para tratamento de doenças alérgicas ou outras condições inflamatórias ou prevenção de doença, de rinite alérgica ou asma, composição, e, uso de um composto. |
| EP3268036A1 (en) | 2015-03-10 | 2018-01-17 | GlaxoSmithKline Biologicals S.A. | Compositions and uses |
| JP6744622B2 (ja) * | 2016-06-16 | 2020-08-19 | 学校法人上智学院 | ピペリジン化合物の製造方法 |
| CN109563075B (zh) * | 2016-08-08 | 2022-09-30 | 默克专利股份公司 | Tlr7/8拮抗剂及其用途 |
| CN117402852A (zh) | 2016-10-14 | 2024-01-16 | 精密生物科学公司 | 对乙肝病毒基因组中的识别序列特异性的工程化大范围核酸酶 |
| AU2018392213B2 (en) | 2017-12-20 | 2021-03-04 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein |
| AU2018392212B9 (en) | 2017-12-20 | 2021-03-18 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein |
| JP7050165B2 (ja) | 2018-02-26 | 2022-04-07 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｂｖ複製阻害剤としての置換ピロリジン化合物 |
| WO2019195181A1 (en) | 2018-04-05 | 2019-10-10 | Gilead Sciences, Inc. | Antibodies and fragments thereof that bind hepatitis b virus protein x |
| TWI818007B (zh) | 2018-04-06 | 2023-10-11 | 捷克科學院有機化學與生物化學研究所 | 2'3'-環二核苷酸 |
| TWI833744B (zh) | 2018-04-06 | 2024-03-01 | 捷克科學院有機化學與生物化學研究所 | 3'3'-環二核苷酸 |
| TW202005654A (zh) | 2018-04-06 | 2020-02-01 | 捷克科學院有機化學與生物化學研究所 | ２，２，─環二核苷酸 |
| TW201945388A (zh) | 2018-04-12 | 2019-12-01 | 美商精密生物科學公司 | 對b型肝炎病毒基因體中之識別序列具有特異性之最佳化之經工程化巨核酸酶 |
| TW202014193A (zh) | 2018-05-03 | 2020-04-16 | 捷克科學院有機化學與生物化學研究所 | 包含碳環核苷酸之2’3’－環二核苷酸 |
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| CA3129022C (en) | 2019-03-07 | 2023-08-01 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3'-cyclic dinucleotides and prodrugs thereof |
| EP3935065A1 (en) | 2019-03-07 | 2022-01-12 | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. | 3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator |
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| WO2022241134A1 (en) | 2021-05-13 | 2022-11-17 | Gilead Sciences, Inc. | COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS |
| AU2022298639C1 (en) | 2021-06-23 | 2025-07-17 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| KR20240005901A (ko) | 2021-06-23 | 2024-01-12 | 길리애드 사이언시즈, 인코포레이티드 | 디아실글리세롤 키나제 조절 화합물 |
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| CN118165930B (zh) * | 2024-04-16 | 2024-10-01 | 颖奕干细胞生物科技(海南)有限公司 | 一种长效维持血液中pbmc细胞的方法 |
| US20250345390A1 (en) | 2024-05-13 | 2025-11-13 | Gilead Sciences, Inc. | Combination therapies |
| WO2025240246A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies with ribavirin |
| US20250345389A1 (en) | 2024-05-13 | 2025-11-13 | Gilead Sciences, Inc. | Combination therapies |
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| BR112017009648A2 (pt) * | 2014-11-13 | 2017-12-19 | Glaxosmithkline Biologicals Sa | composto, métodos para tratamento de doenças alérgicas ou outras condições inflamatórias ou prevenção de doença, de rinite alérgica ou asma, composição, e, uso de um composto. |
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2015
- 2015-11-13 BR BR112017009648A patent/BR112017009648A2/pt not_active Application Discontinuation
- 2015-11-13 JP JP2017525536A patent/JP2017533925A/ja not_active Ceased
- 2015-11-13 MX MX2017006302A patent/MX2017006302A/es unknown
- 2015-11-13 EP EP15797460.1A patent/EP3218377B1/en active Active
- 2015-11-13 CN CN201580071475.2A patent/CN107108628A/zh active Pending
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- 2015-11-13 ES ES15797460T patent/ES2917887T3/es active Active
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2020
- 2020-01-17 US US16/745,569 patent/US10919894B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010018134A1 (en) * | 2008-08-11 | 2010-02-18 | Smithkline Beecham Corporation | Novel adenine derivatives |
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| US10919894B2 (en) | 2021-02-16 |
| ES2917887T3 (es) | 2022-07-12 |
| US10584125B2 (en) | 2020-03-10 |
| EP3218377B1 (en) | 2022-04-13 |
| WO2016075661A1 (en) | 2016-05-19 |
| EP3218377A1 (en) | 2017-09-20 |
| US20180291026A1 (en) | 2018-10-11 |
| BR112017009648A2 (pt) | 2017-12-19 |
| MX2017006302A (es) | 2018-02-16 |
| US20200223849A1 (en) | 2020-07-16 |
| JP2017533925A (ja) | 2017-11-16 |
| BE1023340A1 (fr) | 2017-02-08 |
| CN107108628A (zh) | 2017-08-29 |
| CA2967248A1 (en) | 2016-05-19 |
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