BE1000730A5 - Nouvelles tetrahydrocarbazolones, composition pharmaceutique les contenant et leur procede de preparation. - Google Patents
Nouvelles tetrahydrocarbazolones, composition pharmaceutique les contenant et leur procede de preparation. Download PDFInfo
- Publication number
- BE1000730A5 BE1000730A5 BE8700814A BE8700814A BE1000730A5 BE 1000730 A5 BE1000730 A5 BE 1000730A5 BE 8700814 A BE8700814 A BE 8700814A BE 8700814 A BE8700814 A BE 8700814A BE 1000730 A5 BE1000730 A5 BE 1000730A5
- Authority
- BE
- Belgium
- Prior art keywords
- tetrahydrocarbazolones
- novel
- preparation
- pharmaceutical composition
- composition containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- ZBFZXENHYIJZGA-UHFFFAOYSA-N 2,3,4,4a-tetrahydrocarbazol-1-one Chemical class C1=CC=C2C3CCCC(=O)C3=NC2=C1 ZBFZXENHYIJZGA-UHFFFAOYSA-N 0.000 abstract 1
- 102000035037 5-HT3 receptors Human genes 0.000 abstract 1
- 108091005477 5-HT3 receptors Proteins 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000003636 chemical group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868617994A GB8617994D0 (en) | 1986-07-23 | 1986-07-23 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1000730A5 true BE1000730A5 (fr) | 1989-03-21 |
Family
ID=10601571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE8700814A BE1000730A5 (fr) | 1986-07-23 | 1987-07-22 | Nouvelles tetrahydrocarbazolones, composition pharmaceutique les contenant et leur procede de preparation. |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS6335570A (enrdf_load_stackoverflow) |
| BE (1) | BE1000730A5 (enrdf_load_stackoverflow) |
| CH (1) | CH674008A5 (enrdf_load_stackoverflow) |
| DE (1) | DE3724322A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2601951B1 (enrdf_load_stackoverflow) |
| GB (2) | GB8617994D0 (enrdf_load_stackoverflow) |
| IT (1) | IT1211667B (enrdf_load_stackoverflow) |
| NL (1) | NL8701728A (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
| JPH0669963B2 (ja) | 1989-04-21 | 1994-09-07 | サンド・アクチエンゲゼルシャフト | ５ｈｔ▲下３▼受容体拮抗薬の治療的用途 |
| WO1993000074A1 (en) * | 1991-06-26 | 1993-01-07 | Sepracor, Inc. | Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron |
| ES2043535B1 (es) * | 1992-03-13 | 1994-08-01 | Vita Invest Sa | Procedimiento para la obtencion de la 1,2,3,9-tetrahidro-9-metil-3-(2-metil-1h-imidazol-1-il)metil*-4h-carbazol-4-ona. |
| GB9214184D0 (en) * | 1992-07-03 | 1992-08-12 | Smithkline Beecham Plc | Pharmaceuticals |
| CA2106642C (en) * | 1992-10-14 | 2005-08-16 | Peter Bod | Carbazolone derivatives and process for preparing the same |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2153821A (en) * | 1984-01-25 | 1985-08-29 | Glaxo Group Ltd | 3-Imidazolylmethyl-1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives |
| EP0191562A2 (en) * | 1985-01-23 | 1986-08-20 | Glaxo Group Limited | Tetrahydrocarbazolone derivatives |
| EP0210840A2 (en) * | 1985-07-24 | 1987-02-04 | Glaxo Group Limited | Substituted imidazolylmethyltetrahydro-carbazolones |
| EP0219193A1 (en) * | 1985-07-24 | 1987-04-22 | Glaxo Group Limited | Tetrahydrocarbazolone derivatives, processes for their preparation and pharmaceutical compositions containing them |
| EP0219929A1 (en) * | 1985-07-24 | 1987-04-29 | Glaxo Group Limited | Process for the preparation of 3-imidazolylmethyltetrahydrocarbazolones |
| EP0221629A1 (en) * | 1985-07-24 | 1987-05-13 | Glaxo Group Limited | Process for the preparation of 3-imidazolylmethyltetrahydrocarbazolones |
-
1986
- 1986-07-23 GB GB868617994A patent/GB8617994D0/en active Pending
-
1987
- 1987-07-22 FR FR878710388A patent/FR2601951B1/fr not_active Expired - Fee Related
- 1987-07-22 IT IT8748207A patent/IT1211667B/it active
- 1987-07-22 DE DE19873724322 patent/DE3724322A1/de not_active Withdrawn
- 1987-07-22 JP JP62183240A patent/JPS6335570A/ja active Pending
- 1987-07-22 CH CH2780/87A patent/CH674008A5/fr not_active IP Right Cessation
- 1987-07-22 NL NL8701728A patent/NL8701728A/nl not_active Application Discontinuation
- 1987-07-22 GB GB8717353A patent/GB2192885B/en not_active Expired - Fee Related
- 1987-07-22 BE BE8700814A patent/BE1000730A5/fr not_active IP Right Cessation
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2153821A (en) * | 1984-01-25 | 1985-08-29 | Glaxo Group Ltd | 3-Imidazolylmethyl-1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives |
| EP0191562A2 (en) * | 1985-01-23 | 1986-08-20 | Glaxo Group Limited | Tetrahydrocarbazolone derivatives |
| EP0210840A2 (en) * | 1985-07-24 | 1987-02-04 | Glaxo Group Limited | Substituted imidazolylmethyltetrahydro-carbazolones |
| EP0219193A1 (en) * | 1985-07-24 | 1987-04-22 | Glaxo Group Limited | Tetrahydrocarbazolone derivatives, processes for their preparation and pharmaceutical compositions containing them |
| EP0219929A1 (en) * | 1985-07-24 | 1987-04-29 | Glaxo Group Limited | Process for the preparation of 3-imidazolylmethyltetrahydrocarbazolones |
| EP0221629A1 (en) * | 1985-07-24 | 1987-05-13 | Glaxo Group Limited | Process for the preparation of 3-imidazolylmethyltetrahydrocarbazolones |
Also Published As
| Publication number | Publication date |
|---|---|
| GB8617994D0 (en) | 1986-08-28 |
| IT1211667B (it) | 1989-11-03 |
| DE3724322A1 (de) | 1988-01-28 |
| GB8717353D0 (en) | 1987-08-26 |
| GB2192885A (en) | 1988-01-27 |
| FR2601951B1 (fr) | 1991-04-26 |
| NL8701728A (nl) | 1988-02-16 |
| GB2192885B (en) | 1990-02-07 |
| IT8748207A0 (it) | 1987-07-22 |
| JPS6335570A (ja) | 1988-02-16 |
| FR2601951A1 (fr) | 1988-01-29 |
| CH674008A5 (enrdf_load_stackoverflow) | 1990-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: GLAXO GROUP LTD Effective date: 19930731 |