AU8169387A - Imidazopyridine compounds and processes for preparation thereof - Google Patents

Imidazopyridine compounds and processes for preparation thereof

Info

Publication number
AU8169387A
AU8169387A AU81693/87A AU8169387A AU8169387A AU 8169387 A AU8169387 A AU 8169387A AU 81693/87 A AU81693/87 A AU 81693/87A AU 8169387 A AU8169387 A AU 8169387A AU 8169387 A AU8169387 A AU 8169387A
Authority
AU
Australia
Prior art keywords
methyl
alkyl
nujol
propynyl
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU81693/87A
Other languages
English (en)
Inventor
Hiromichi Itani
Masanobu Nagano
Youichi Shiokawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628262A external-priority patent/GB8628262D0/en
Priority claimed from GB878723439A external-priority patent/GB8723439D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of AU8169387A publication Critical patent/AU8169387A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU81693/87A 1986-11-26 1987-11-25 Imidazopyridine compounds and processes for preparation thereof Abandoned AU8169387A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB868628262A GB8628262D0 (en) 1986-11-26 1986-11-26 Imidazopyridine compounds
GB8628262 1986-11-26
GB8723439 1987-10-06
GB878723439A GB8723439D0 (en) 1987-10-06 1987-10-06 Imidazopyridine compounds

Publications (1)

Publication Number Publication Date
AU8169387A true AU8169387A (en) 1988-06-02

Family

ID=26291587

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81693/87A Abandoned AU8169387A (en) 1986-11-26 1987-11-25 Imidazopyridine compounds and processes for preparation thereof

Country Status (13)

Country Link
US (1) US4831041A (enExample)
EP (1) EP0268989B1 (enExample)
KR (1) KR880006237A (enExample)
CN (1) CN87108027A (enExample)
AU (1) AU8169387A (enExample)
DE (1) DE3780263T2 (enExample)
DK (1) DK608887A (enExample)
ES (1) ES2064310T3 (enExample)
FI (1) FI875157A7 (enExample)
GR (1) GR3005685T3 (enExample)
HU (1) HUT45526A (enExample)
IL (1) IL84522A0 (enExample)
NO (1) NO874904L (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU593802B2 (en) * 1985-06-04 1990-02-22 Fujisawa Pharmaceutical Co., Ltd. Imidazo(1,2-a)pyridines and imidazo(1,2-a)pyrazines
AU597108B2 (en) * 1986-09-22 1990-05-24 Ortho Pharmaceutical Corporation 2- or-3- aryl substituted imidazo(1,2-a)pyridines

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0370056A1 (de) * 1987-07-16 1990-05-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazole
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound
CA2048110C (en) * 1990-07-30 2002-06-25 Muneo Takatani Imidazopyridine derivatives and their use
MY110439A (en) * 1991-02-07 1998-05-30 Ishihara Sangyo Kaisha N-phenylcarbamate compound, process for preparing the same and biocidal composition for control of harmful organisms
GB9201693D0 (en) * 1992-01-27 1992-03-11 Smithkline Beecham Intercredit Compounds
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
UA48122C2 (uk) * 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
CN1046726C (zh) * 1994-07-28 1999-11-24 比克·古尔顿·劳姆贝尔格化学公司 咪唑并吡啶－吡咯烷酮、其制法和药用
JPH10505331A (ja) * 1994-07-28 1998-05-26 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンジルイミダゾピリジン
AU3221795A (en) * 1994-07-28 1996-02-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Halogenated imidazopyridines
EP0882048B1 (de) * 1996-01-26 2005-05-04 ALTANA Pharma AG 3-alkylimidazopyridine
AU1545297A (en) * 1996-01-26 1997-08-20 Byk Gulden Imidazopyridine halides
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
DE10145457A1 (de) 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
PL2797416T3 (pl) 2011-12-28 2017-12-29 Global Blood Therapeutics, Inc. Podstawione związki benzaldehydowe i sposoby ich zastosowania do zwiększania natlenienia tkanek
US9012450B2 (en) 2011-12-28 2015-04-21 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
JP6426694B2 (ja) 2013-03-15 2018-11-21 グローバル ブラッド セラピューティクス インコーポレイテッド ヘモグロビンの修飾のための化合物及びその使用
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
BR112015021982B1 (pt) 2013-03-15 2022-12-13 Global Blood Therapeutics, Inc Compostos e seus usos para a modulação de hemoglobina
EP2968299B1 (en) 2013-03-15 2021-01-20 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
AP2016009261A0 (en) 2014-02-07 2016-06-30 Global Blood Therapeutics Inc Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
PL3383392T3 (pl) 2015-12-04 2025-11-17 Global Blood Therapeutics, Inc. Schematy dawkowania dla 2-hydroksy-6-((2-(1-izopropylo-1H-pirazol-5-ilo)pirydyn3-ylo)metoksy)benzaldehydu
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
EP3860975B1 (en) 2018-10-01 2023-10-18 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU593802B2 (en) * 1985-06-04 1990-02-22 Fujisawa Pharmaceutical Co., Ltd. Imidazo(1,2-a)pyridines and imidazo(1,2-a)pyrazines
AU597108B2 (en) * 1986-09-22 1990-05-24 Ortho Pharmaceutical Corporation 2- or-3- aryl substituted imidazo(1,2-a)pyridines

Also Published As

Publication number Publication date
DK608887A (da) 1988-05-27
EP0268989A1 (en) 1988-06-01
KR880006237A (ko) 1988-07-22
EP0268989B1 (en) 1992-07-08
DE3780263T2 (de) 1992-12-24
DE3780263D1 (de) 1992-08-13
NO874904L (no) 1988-05-27
DK608887D0 (da) 1987-11-19
FI875157A7 (fi) 1988-05-27
FI875157A0 (fi) 1987-11-23
CN87108027A (zh) 1988-06-08
ES2064310T3 (es) 1995-02-01
GR3005685T3 (enExample) 1993-06-07
HUT45526A (en) 1988-07-28
NO874904D0 (no) 1987-11-25
IL84522A0 (en) 1988-04-29
US4831041A (en) 1989-05-16

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