AU784275B2 - Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds - Google Patents

Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds Download PDF

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Publication number
AU784275B2
AU784275B2 AU65474/00A AU6547400A AU784275B2 AU 784275 B2 AU784275 B2 AU 784275B2 AU 65474/00 A AU65474/00 A AU 65474/00A AU 6547400 A AU6547400 A AU 6547400A AU 784275 B2 AU784275 B2 AU 784275B2
Authority
AU
Australia
Prior art keywords
acid
formula
compound
alkyl
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU65474/00A
Other languages
English (en)
Other versions
AU6547400A (en
Inventor
Stephane Caron
Enrique Vazquez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of AU6547400A publication Critical patent/AU6547400A/en
Application granted granted Critical
Publication of AU784275B2 publication Critical patent/AU784275B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU65474/00A 1999-10-18 2000-10-12 Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds Ceased AU784275B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16022699P 1999-10-18 1999-10-18
US60/160226 1999-10-18

Publications (2)

Publication Number Publication Date
AU6547400A AU6547400A (en) 2001-04-26
AU784275B2 true AU784275B2 (en) 2006-03-02

Family

ID=22576040

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65474/00A Ceased AU784275B2 (en) 1999-10-18 2000-10-12 Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds

Country Status (24)

Country Link
US (2) US6486325B1 (en:Method)
EP (1) EP1095939B1 (en:Method)
JP (1) JP3564685B2 (en:Method)
KR (1) KR100459952B1 (en:Method)
CN (1) CN1293193A (en:Method)
AR (1) AR026053A1 (en:Method)
AT (1) ATE257477T1 (en:Method)
AU (1) AU784275B2 (en:Method)
BR (1) BR0004901A (en:Method)
CA (1) CA2323315C (en:Method)
CZ (1) CZ299029B6 (en:Method)
DE (1) DE60007599T2 (en:Method)
DK (1) DK1095939T3 (en:Method)
ES (1) ES2211455T3 (en:Method)
HU (1) HUP0004061A2 (en:Method)
ID (1) ID27627A (en:Method)
IL (1) IL139012A (en:Method)
IN (1) IN190078B (en:Method)
PL (1) PL343290A1 (en:Method)
PT (1) PT1095939E (en:Method)
RU (1) RU2184116C1 (en:Method)
TR (1) TR200003002A2 (en:Method)
YU (1) YU60600A (en:Method)
ZA (1) ZA200005695B (en:Method)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
WO2003053929A1 (en) * 2001-12-21 2003-07-03 Toray Fine Chemicals Co., Ltd. Process for production of optically active cis-piperidine derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999025714A1 (en) * 1997-11-19 1999-05-27 Pfizer Pharmaceuticals Inc. Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance p antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
JPH0794440B2 (ja) * 1991-03-26 1995-10-11 フアイザー・インコーポレイテツド 置換ピペリジンの立体選択的製造
US5294744A (en) * 1993-04-20 1994-03-15 Pfizer Inc. Formylation process for aromatic aldehydes
KR19980703354A (ko) * 1995-03-27 1998-10-15 나카토미히로타카 피페리딘 유도체
JP3042894B2 (ja) * 1995-07-07 2000-05-22 ファイザー製薬株式会社 サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
EP1178984B1 (en) * 1999-05-21 2003-03-19 Pfizer Products Inc. 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999025714A1 (en) * 1997-11-19 1999-05-27 Pfizer Pharmaceuticals Inc. Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance p antagonists

Also Published As

Publication number Publication date
US20030236268A1 (en) 2003-12-25
JP2001151773A (ja) 2001-06-05
EP1095939A2 (en) 2001-05-02
DE60007599D1 (de) 2004-02-12
ID27627A (id) 2001-04-19
AU6547400A (en) 2001-04-26
HUP0004061A2 (hu) 2002-05-29
CA2323315C (en) 2008-07-29
ES2211455T3 (es) 2004-07-16
US6486325B1 (en) 2002-11-26
DK1095939T3 (da) 2004-04-13
IL139012A (en) 2007-06-17
BR0004901A (pt) 2001-05-29
PT1095939E (pt) 2004-04-30
CA2323315A1 (en) 2001-04-18
CZ299029B6 (cs) 2008-04-09
IN190078B (en:Method) 2003-06-07
AR026053A1 (es) 2002-12-26
DE60007599T2 (de) 2004-11-11
TR200003002A2 (tr) 2001-05-21
ZA200005695B (en) 2002-04-16
HU0004061D0 (en) 2000-12-28
KR20010051069A (ko) 2001-06-25
EP1095939A3 (en) 2001-05-23
KR100459952B1 (ko) 2004-12-04
IL139012A0 (en) 2001-11-25
RU2184116C1 (ru) 2002-06-27
CN1293193A (zh) 2001-05-02
JP3564685B2 (ja) 2004-09-15
ATE257477T1 (de) 2004-01-15
PL343290A1 (en) 2001-04-23
YU60600A (sh) 2002-12-10
EP1095939B1 (en) 2004-01-07
CZ20003840A3 (cs) 2002-02-13

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