AR026053A1 - Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometiltrifluorometilicos - Google Patents
Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometiltrifluorometilicosInfo
- Publication number
- AR026053A1 AR026053A1 ARP000105423A ARP000105423A AR026053A1 AR 026053 A1 AR026053 A1 AR 026053A1 AR P000105423 A ARP000105423 A AR P000105423A AR P000105423 A ARP000105423 A AR P000105423A AR 026053 A1 AR026053 A1 AR 026053A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- compounds
- procedure
- piperidinilaminometiltrifluorometilic
- eternal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La presente se refiere a un procedimiento novedoso para la preparacion de una mezcla diastereomérica de compuestos éteres cíclicos piperidinilaminometil deformulas (1) y (2) y las sales farmacéuticamente aceptables de los mismos, en las que R1 esalq uilo C1-6; R2 es alquilo C1-6, haloalquilo C1-6 o fenilo ofenilo sustituido; R3 es hidrogeno o halo; m es cero, uno o dos, y estando dicha mezcla muy enriquecida en el compuesto de formula (1), y a un procedimientonovedoso para la preparacion ypurif icacion de compuestos intermedios utiles en la preparacion de los compuestos de formulas (1) y (2).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16022699P | 1999-10-18 | 1999-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR026053A1 true AR026053A1 (es) | 2002-12-26 |
Family
ID=22576040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000105423A AR026053A1 (es) | 1999-10-18 | 2000-10-13 | Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometiltrifluorometilicos |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US6486325B1 (es) |
| EP (1) | EP1095939B1 (es) |
| JP (1) | JP3564685B2 (es) |
| KR (1) | KR100459952B1 (es) |
| CN (1) | CN1293193A (es) |
| AR (1) | AR026053A1 (es) |
| AT (1) | ATE257477T1 (es) |
| AU (1) | AU784275B2 (es) |
| BR (1) | BR0004901A (es) |
| CA (1) | CA2323315C (es) |
| CZ (1) | CZ299029B6 (es) |
| DE (1) | DE60007599T2 (es) |
| DK (1) | DK1095939T3 (es) |
| ES (1) | ES2211455T3 (es) |
| HU (1) | HUP0004061A2 (es) |
| ID (1) | ID27627A (es) |
| IL (1) | IL139012A (es) |
| IN (1) | IN190078B (es) |
| PL (1) | PL343290A1 (es) |
| PT (1) | PT1095939E (es) |
| RU (1) | RU2184116C1 (es) |
| TR (1) | TR200003002A2 (es) |
| YU (1) | YU60600A (es) |
| ZA (1) | ZA200005695B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW426667B (en) * | 1997-11-19 | 2001-03-21 | Pfizer | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists |
| WO2003053929A1 (fr) * | 2001-12-21 | 2003-07-03 | Toray Fine Chemicals Co., Ltd. | Procede de production de derives de cis-piperidine optiquement actifs |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ293955B6 (cs) * | 1991-03-26 | 2004-08-18 | Pfizeráinc | Postup přípravy substituovaných piperidinů |
| US5294744A (en) * | 1993-04-20 | 1994-03-15 | Pfizer Inc. | Formylation process for aromatic aldehydes |
| WO1997003066A1 (en) * | 1995-07-07 | 1997-01-30 | Pfizer Pharmaceuticals Inc. | Substituted benzolactam compounds as substance p antagonists |
| TW426667B (en) * | 1997-11-19 | 2001-03-21 | Pfizer | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists |
| WO2000071538A2 (en) * | 1999-05-21 | 2000-11-30 | Pfizer Products Inc. | 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives |
-
2000
- 2000-10-02 ES ES00308640T patent/ES2211455T3/es not_active Expired - Lifetime
- 2000-10-02 PT PT00308640T patent/PT1095939E/pt unknown
- 2000-10-02 EP EP00308640A patent/EP1095939B1/en not_active Expired - Lifetime
- 2000-10-02 DK DK00308640T patent/DK1095939T3/da active
- 2000-10-02 DE DE60007599T patent/DE60007599T2/de not_active Expired - Fee Related
- 2000-10-02 AT AT00308640T patent/ATE257477T1/de not_active IP Right Cessation
- 2000-10-05 YU YU60600A patent/YU60600A/sh unknown
- 2000-10-05 JP JP2000305667A patent/JP3564685B2/ja not_active Expired - Fee Related
- 2000-10-12 AU AU65474/00A patent/AU784275B2/en not_active Ceased
- 2000-10-12 IL IL139012A patent/IL139012A/en not_active IP Right Cessation
- 2000-10-13 IN IN924MU2000 patent/IN190078B/en unknown
- 2000-10-13 AR ARP000105423A patent/AR026053A1/es unknown
- 2000-10-16 ZA ZA200005695A patent/ZA200005695B/xx unknown
- 2000-10-16 ID IDP20000892D patent/ID27627A/id unknown
- 2000-10-16 CA CA002323315A patent/CA2323315C/en not_active Expired - Fee Related
- 2000-10-16 TR TR2000/03002A patent/TR200003002A2/xx unknown
- 2000-10-17 HU HU0004061A patent/HUP0004061A2/hu unknown
- 2000-10-17 US US09/690,346 patent/US6486325B1/en not_active Expired - Fee Related
- 2000-10-17 CN CN00125993A patent/CN1293193A/zh active Pending
- 2000-10-17 CZ CZ20003840A patent/CZ299029B6/cs not_active IP Right Cessation
- 2000-10-17 KR KR10-2000-0060966A patent/KR100459952B1/ko not_active IP Right Cessation
- 2000-10-17 RU RU2000126151/04A patent/RU2184116C1/ru not_active IP Right Cessation
- 2000-10-18 BR BR0004901-8A patent/BR0004901A/pt not_active Application Discontinuation
- 2000-10-18 PL PL00343290A patent/PL343290A1/xx not_active Application Discontinuation
-
2002
- 2002-11-13 US US10/065,725 patent/US20030236268A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200005695B (en) | 2002-04-16 |
| TR200003002A2 (tr) | 2001-05-21 |
| JP2001151773A (ja) | 2001-06-05 |
| AU6547400A (en) | 2001-04-26 |
| HU0004061D0 (en) | 2000-12-28 |
| YU60600A (sh) | 2002-12-10 |
| IL139012A (en) | 2007-06-17 |
| KR20010051069A (ko) | 2001-06-25 |
| EP1095939B1 (en) | 2004-01-07 |
| JP3564685B2 (ja) | 2004-09-15 |
| PL343290A1 (en) | 2001-04-23 |
| EP1095939A3 (en) | 2001-05-23 |
| KR100459952B1 (ko) | 2004-12-04 |
| IN190078B (es) | 2003-06-07 |
| ES2211455T3 (es) | 2004-07-16 |
| RU2184116C1 (ru) | 2002-06-27 |
| IL139012A0 (en) | 2001-11-25 |
| BR0004901A (pt) | 2001-05-29 |
| US20030236268A1 (en) | 2003-12-25 |
| CA2323315C (en) | 2008-07-29 |
| US6486325B1 (en) | 2002-11-26 |
| CA2323315A1 (en) | 2001-04-18 |
| CN1293193A (zh) | 2001-05-02 |
| EP1095939A2 (en) | 2001-05-02 |
| AU784275B2 (en) | 2006-03-02 |
| DE60007599D1 (de) | 2004-02-12 |
| ID27627A (id) | 2001-04-19 |
| CZ20003840A3 (cs) | 2002-02-13 |
| DK1095939T3 (da) | 2004-04-13 |
| ATE257477T1 (de) | 2004-01-15 |
| DE60007599T2 (de) | 2004-11-11 |
| PT1095939E (pt) | 2004-04-30 |
| HUP0004061A2 (hu) | 2002-05-29 |
| CZ299029B6 (cs) | 2008-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |