CA2323315C - Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds - Google Patents
Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds Download PDFInfo
- Publication number
- CA2323315C CA2323315C CA002323315A CA2323315A CA2323315C CA 2323315 C CA2323315 C CA 2323315C CA 002323315 A CA002323315 A CA 002323315A CA 2323315 A CA2323315 A CA 2323315A CA 2323315 C CA2323315 C CA 2323315C
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- formula
- compound
- acid
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16022699P | 1999-10-18 | 1999-10-18 | |
US60/160,226 | 1999-10-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2323315A1 CA2323315A1 (en) | 2001-04-18 |
CA2323315C true CA2323315C (en) | 2008-07-29 |
Family
ID=22576040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002323315A Expired - Fee Related CA2323315C (en) | 1999-10-18 | 2000-10-16 | Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds |
Country Status (24)
Country | Link |
---|---|
US (2) | US6486325B1 (es) |
EP (1) | EP1095939B1 (es) |
JP (1) | JP3564685B2 (es) |
KR (1) | KR100459952B1 (es) |
CN (1) | CN1293193A (es) |
AR (1) | AR026053A1 (es) |
AT (1) | ATE257477T1 (es) |
AU (1) | AU784275B2 (es) |
BR (1) | BR0004901A (es) |
CA (1) | CA2323315C (es) |
CZ (1) | CZ299029B6 (es) |
DE (1) | DE60007599T2 (es) |
DK (1) | DK1095939T3 (es) |
ES (1) | ES2211455T3 (es) |
HU (1) | HUP0004061A2 (es) |
ID (1) | ID27627A (es) |
IL (1) | IL139012A (es) |
IN (1) | IN190078B (es) |
PL (1) | PL343290A1 (es) |
PT (1) | PT1095939E (es) |
RU (1) | RU2184116C1 (es) |
TR (1) | TR200003002A2 (es) |
YU (1) | YU60600A (es) |
ZA (1) | ZA200005695B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW426667B (en) * | 1997-11-19 | 2001-03-21 | Pfizer | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists |
WO2003053929A1 (fr) * | 2001-12-21 | 2003-07-03 | Toray Fine Chemicals Co., Ltd. | Procede de production de derives de cis-piperidine optiquement actifs |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0581777A1 (en) * | 1991-03-26 | 1994-02-09 | Pfizer Inc. | Stereoselective preparation of substituted piperidines |
US5294744A (en) * | 1993-04-20 | 1994-03-15 | Pfizer Inc. | Formylation process for aromatic aldehydes |
ES2155601T3 (es) * | 1995-07-07 | 2001-05-16 | Pfizer | Compuestos de benzolactama sustituidos como antagonistas de la sustancia p. |
TW426667B (en) * | 1997-11-19 | 2001-03-21 | Pfizer | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists |
CA2374643C (en) * | 1999-05-21 | 2006-02-14 | Pfizer Products Inc. | 1-trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives as substance p antagonists |
-
2000
- 2000-10-02 AT AT00308640T patent/ATE257477T1/de not_active IP Right Cessation
- 2000-10-02 ES ES00308640T patent/ES2211455T3/es not_active Expired - Lifetime
- 2000-10-02 DE DE60007599T patent/DE60007599T2/de not_active Expired - Fee Related
- 2000-10-02 PT PT00308640T patent/PT1095939E/pt unknown
- 2000-10-02 DK DK00308640T patent/DK1095939T3/da active
- 2000-10-02 EP EP00308640A patent/EP1095939B1/en not_active Expired - Lifetime
- 2000-10-05 YU YU60600A patent/YU60600A/sh unknown
- 2000-10-05 JP JP2000305667A patent/JP3564685B2/ja not_active Expired - Fee Related
- 2000-10-12 AU AU65474/00A patent/AU784275B2/en not_active Ceased
- 2000-10-12 IL IL139012A patent/IL139012A/en not_active IP Right Cessation
- 2000-10-13 IN IN924MU2000 patent/IN190078B/en unknown
- 2000-10-13 AR ARP000105423A patent/AR026053A1/es unknown
- 2000-10-16 ID IDP20000892D patent/ID27627A/id unknown
- 2000-10-16 TR TR2000/03002A patent/TR200003002A2/xx unknown
- 2000-10-16 ZA ZA200005695A patent/ZA200005695B/xx unknown
- 2000-10-16 CA CA002323315A patent/CA2323315C/en not_active Expired - Fee Related
- 2000-10-17 CZ CZ20003840A patent/CZ299029B6/cs not_active IP Right Cessation
- 2000-10-17 US US09/690,346 patent/US6486325B1/en not_active Expired - Fee Related
- 2000-10-17 KR KR10-2000-0060966A patent/KR100459952B1/ko not_active IP Right Cessation
- 2000-10-17 RU RU2000126151/04A patent/RU2184116C1/ru not_active IP Right Cessation
- 2000-10-17 CN CN00125993A patent/CN1293193A/zh active Pending
- 2000-10-17 HU HU0004061A patent/HUP0004061A2/hu unknown
- 2000-10-18 PL PL00343290A patent/PL343290A1/xx not_active Application Discontinuation
- 2000-10-18 BR BR0004901-8A patent/BR0004901A/pt not_active Application Discontinuation
-
2002
- 2002-11-13 US US10/065,725 patent/US20030236268A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PL343290A1 (en) | 2001-04-23 |
CZ20003840A3 (cs) | 2002-02-13 |
JP3564685B2 (ja) | 2004-09-15 |
ES2211455T3 (es) | 2004-07-16 |
ZA200005695B (en) | 2002-04-16 |
PT1095939E (pt) | 2004-04-30 |
DK1095939T3 (da) | 2004-04-13 |
BR0004901A (pt) | 2001-05-29 |
HU0004061D0 (en) | 2000-12-28 |
IL139012A0 (en) | 2001-11-25 |
KR100459952B1 (ko) | 2004-12-04 |
IL139012A (en) | 2007-06-17 |
US20030236268A1 (en) | 2003-12-25 |
HUP0004061A2 (hu) | 2002-05-29 |
DE60007599D1 (de) | 2004-02-12 |
EP1095939B1 (en) | 2004-01-07 |
CN1293193A (zh) | 2001-05-02 |
AR026053A1 (es) | 2002-12-26 |
ID27627A (id) | 2001-04-19 |
IN190078B (es) | 2003-06-07 |
EP1095939A2 (en) | 2001-05-02 |
US6486325B1 (en) | 2002-11-26 |
CA2323315A1 (en) | 2001-04-18 |
EP1095939A3 (en) | 2001-05-23 |
CZ299029B6 (cs) | 2008-04-09 |
AU6547400A (en) | 2001-04-26 |
ATE257477T1 (de) | 2004-01-15 |
KR20010051069A (ko) | 2001-06-25 |
RU2184116C1 (ru) | 2002-06-27 |
AU784275B2 (en) | 2006-03-02 |
DE60007599T2 (de) | 2004-11-11 |
YU60600A (sh) | 2002-12-10 |
JP2001151773A (ja) | 2001-06-05 |
TR200003002A2 (tr) | 2001-05-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1996014297A1 (fr) | Nouveaux derives de lactame | |
US6211225B1 (en) | Heterocyclic aminopyrrolidine derivatives as melatonergic agents | |
EP0391799A1 (fr) | Nouveaux sulfonamides dérivés d'acides benzocycliques ou benzohétérocycliques, leur préparation et leur application en thérapeutique | |
EP0774461B1 (en) | Excitatory amino acid derivatives | |
CA2323315C (en) | Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds | |
EA002633B1 (ru) | Способ синтеза производных хинолина | |
CA2179205A1 (en) | Benzisothiazolyl-substituted aminomethylchromans | |
AU4097199A (en) | Heterocyclic cis cyclopropane derivatives as melatonergic agents | |
KR100962325B1 (ko) | 치환된 테트라사이클릭 테트라하이드로푸란 유도체의 신규만델레이트 염 | |
EP1456193B1 (en) | PREPARATION OF TRANS-FUSED 3,3a,8,12b-TETRAHYDRO-2 i H /i -DIBENZO 3,4:6,7]CYCLOHEPTA 1,2-b]FURAN DERIVATIVES | |
EP0338895A1 (fr) | Nouveaux dérivés hétéroarotinoides, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent | |
JP3064017B2 (ja) | (s)−3−(2−チエニルチオ)酪酸及びアナログの合成 | |
MXPA00010173A (es) | Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometil trifluorometilicos | |
US20030233002A1 (en) | Synthesis of 2-Acyl substituted chromanes and intermediates thereof | |
JPH06508136A (ja) | L−アスパラギン酸からの光学活性ラクトンの合成法及び光学活性ラクトンの中間体 | |
CA2468040A1 (en) | Preparation of cis-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives | |
JPH0217169A (ja) | 2―ヒドロキシー3―(4―メトキシフェニル)―3―(2―アミノフェニルチオ)プロピオン酸 8’―フェニルメンチル エステル および その製法 | |
JP2500279C (es) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |