AU769847C - Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application - Google Patents

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application

Info

Publication number
AU769847C
AU769847C AU27034/00A AU2703400A AU769847C AU 769847 C AU769847 C AU 769847C AU 27034/00 A AU27034/00 A AU 27034/00A AU 2703400 A AU2703400 A AU 2703400A AU 769847 C AU769847 C AU 769847C
Authority
AU
Australia
Prior art keywords
asp
ala
tetrapeptide
glu
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27034/00A
Other languages
English (en)
Other versions
AU2703400A (en
AU769847B2 (en
Inventor
Vladimir Khatskelevich Khavinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIJU "KLINIKA INSTITUTA BIOREGULYATSII I GERONTOLOGII"
Original Assignee
OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIJU "KLINIKA INSTITUTA BIOREGULYATSII I GERONTOLOGII"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIJU "KLINIKA INSTITUTA BIOREGULYATSII I GERONTOLOGII" filed Critical OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIJU "KLINIKA INSTITUTA BIOREGULYATSII I GERONTOLOGII"
Publication of AU2703400A publication Critical patent/AU2703400A/en
Application granted granted Critical
Publication of AU769847B2 publication Critical patent/AU769847B2/en
Publication of AU769847C publication Critical patent/AU769847C/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU27034/00A 1999-05-11 2000-01-20 Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application Ceased AU769847C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU99108841/14A RU2157233C1 (ru) 1999-05-11 1999-05-11 Тетрапептид, обладающий геропротекторной активностью, фармакологическое средство на его основе и способ его применения
RO99108841 1999-05-11
PCT/RU2000/000012 WO2000068255A2 (en) 1999-05-11 2000-01-20 Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application

Publications (3)

Publication Number Publication Date
AU2703400A AU2703400A (en) 2000-11-21
AU769847B2 AU769847B2 (en) 2004-02-05
AU769847C true AU769847C (en) 2005-02-17

Family

ID=20219149

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27034/00A Ceased AU769847C (en) 1999-05-11 2000-01-20 Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application

Country Status (11)

Country Link
US (1) US6727227B1 (https=)
EP (1) EP1179008B1 (https=)
JP (1) JP3902406B2 (https=)
AT (1) ATE321068T1 (https=)
AU (1) AU769847C (https=)
CA (1) CA2373128C (https=)
DE (1) DE60026826T2 (https=)
ES (1) ES2259998T3 (https=)
IL (2) IL146432A0 (https=)
RU (1) RU2157233C1 (https=)
WO (1) WO2000068255A2 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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US20050227925A1 (en) * 2004-04-08 2005-10-13 Robbert Benner Compositions capable of reducing elevated blood urea concentration
US6921751B1 (en) * 1998-05-20 2005-07-26 Erasmus Universiteit Rotterdam Immunoregulator
US20030220258A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
US20040202645A1 (en) * 2003-04-08 2004-10-14 Khan Nisar Ahmed Administration of gene-regulatory peptides
EP1138692A1 (en) 2000-03-29 2001-10-04 Erasmus Universiteit Rotterdam Fragments of human chorionic gonadotropin (hcg) as immunoregulator
US8680059B2 (en) * 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
US6844315B2 (en) * 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
US7175679B2 (en) * 2001-03-29 2007-02-13 Biotempt B.V. Oligopeptide treatment of NF-κB mediated inflammation
USRE43279E1 (en) 2000-03-29 2012-03-27 Biotemp B.V. Compositions capable of reducing elevated blood urea concentration
US7576174B2 (en) * 2000-03-29 2009-08-18 Biotempt B.V. Compositions capable of reducing elevated blood urea concentration
EP1300418A1 (en) * 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Gene regulation by oligopeptides
US7358330B2 (en) * 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
RU2161501C1 (ru) * 2000-06-29 2001-01-10 Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" Способ получения пептидов, обладающих тканеспецифической активностью, и фармацевтические композиции на их основе
WO2002090380A1 (en) * 2001-04-17 2002-11-14 Sankt-Peterburgskaya Obschestvennaya Organizatsiya 'institut Bioregulyatsii I Gerontologii Czo Ramn' Tetrapeptide stimulating the retinal function and the method of its application
US7501391B2 (en) 2001-12-21 2009-03-10 Biotempt B.V. Treatment of transplant survival
US7786084B2 (en) * 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
US20040013661A1 (en) * 2001-12-21 2004-01-22 Gert Wensvoort Stratification
US20030224995A1 (en) * 2001-12-21 2003-12-04 Khan Nisar Ahmed Treatment of burns
US7560433B2 (en) * 2001-12-21 2009-07-14 Biotempt B.V. Treatment of multiple sclerosis (MS)
US20080318871A1 (en) * 2001-12-21 2008-12-25 Khan Nisar A Treatment of neurological disorders
US20030220257A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of trauma
US20030220261A1 (en) * 2001-12-21 2003-11-27 Khan Nisar Ahmed Treatment of iatrogenic disease
US20080242837A1 (en) * 2001-12-21 2008-10-02 Khan Nisar A Peptide compositions
US7517529B2 (en) * 2003-04-08 2009-04-14 Biotempt B.V. Treatment of type I diabetes
RU2257910C1 (ru) * 2003-12-25 2005-08-10 Институт физиологически активных веществ Российской Академии Наук (ИФАВ РАН) Растительные экстракты, обладающие геропротекторной активностью и средство на их основе
RU2257909C1 (ru) * 2003-12-25 2005-08-10 Институт физиологически активных веществ Российской Академии Наук (ИФАВ РАН) Концентрат побегов черники и композиции на его основе, обладающие геропротекторной активностью
US20090227505A1 (en) * 2004-01-07 2009-09-10 Biotempt B.V. Methods and uses for protein breakdown products
RU2255756C1 (ru) * 2004-06-22 2005-07-10 Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" Пептидное соединение, восстанавливающее функцию миокарда
RU2255757C1 (ru) * 2004-06-22 2005-07-10 Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" Пептидное соединение, восстанавливающее функцию органов дыхания
RU2297215C2 (ru) * 2005-02-21 2007-04-20 Государственное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет им. акад. И.П. Павлова" МЗ РФ Антиоксидантное средство для лечения катаракты
JP4846799B2 (ja) * 2005-07-05 2011-12-28 バイオテンプト ベー．フェー． 腫瘍の治療
EP1864692A1 (en) * 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
RU2295970C1 (ru) * 2006-05-23 2007-03-27 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Пептид, повышающий резистентность капилляров, фармацевтическая композиция на его основе и способ ее применения
RU2304444C1 (ru) * 2006-05-23 2007-08-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Пептид, обладающий стресспротекторным действием, фармацевтическая композиция на его основе и способ ее применения
RU2301074C1 (ru) * 2006-05-30 2007-06-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Пептид, обладающий иммуногеропротекторным действием, фармацевтическая композиция на его основе и способ ее применения
RU2301678C1 (ru) * 2006-05-30 2007-06-27 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Пептид, стимулирующий регенерацию нейронов центральной нервной системы, фармацевтическая композиция на его основе и способ ее применения
DK2120991T3 (da) * 2007-02-12 2014-04-28 Biotempt Bv Behandling af traumatisk blødning med korte oligopeptider
RU2464816C1 (ru) * 2011-04-14 2012-10-27 Общество с ограниченной ответственностью "Вилави" Композиция биологически активных веществ, обладающая геропротекторной активностью, и способ комплексной коррекции возрастных изменений гормонального баланса, функций эпифиза и антиоксидантного статуса, включающий введение указанной композиции
JP7137745B2 (ja) * 2015-05-22 2022-09-15 ズィ・エイツー・ミルク・カンパニー・リミテッド ベータカゼインａ２および抗酸化能
CA3175267A1 (en) * 2020-04-15 2021-10-21 Anton MALYSHEV Synthetic peptides for modulating the metabotropic glutamate receptor 5
KR102841388B1 (ko) * 2022-08-30 2025-08-01 주식회사 제이포셀 항노화 펩타이드 및 황기 추출물을 포함하는 항노화 화장료 조성물

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JPH078273A (ja) * 1993-06-14 1995-01-13 Kurabo Ind Ltd 接着性動物細胞の無血清培養法
JPH0851980A (ja) * 1994-08-11 1996-02-27 Asahi Glass Co Ltd 合成遺伝子およびこれを用いた癌転移阻害活性を有するペプチドの製造方法
RU2099078C1 (ru) * 1994-12-08 1997-12-20 Акционерное общество закрытого типа "КОМКОН" Средство, обладающее антистрессовым, стресспротекторным, ноотропным, антиалкогольным и антинаркотическим действием, способы профилактики и лечения с его использованием
RU2112512C1 (ru) * 1995-09-22 1998-06-10 Иванов Евгений Васильевич Биологичеcки активная пищевая добавка "глутапирон", обладающая антиканцерогенным и геропротекторным действием
GB2348426B (en) * 1997-04-03 2001-06-27 California Inst Of Techn Enzyme-mediated modification of fibrin for tissue engineering

Also Published As

Publication number Publication date
JP2003526622A (ja) 2003-09-09
ATE321068T1 (de) 2006-04-15
ES2259998T3 (es) 2006-11-01
EP1179008A2 (en) 2002-02-13
AU2703400A (en) 2000-11-21
CA2373128A1 (en) 2000-11-16
DE60026826D1 (de) 2006-05-11
IL146432A0 (en) 2002-07-25
WO2000068255A2 (en) 2000-11-16
CA2373128C (en) 2007-03-13
RU2157233C1 (ru) 2000-10-10
EP1179008B1 (en) 2006-03-22
WO2000068255A3 (en) 2001-06-14
JP3902406B2 (ja) 2007-04-04
AU769847B2 (en) 2004-02-05
IL146432A (en) 2007-06-03
DE60026826T2 (de) 2007-04-12
US6727227B1 (en) 2004-04-27

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Legal Events

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FGA Letters patent sealed or granted (standard patent)
DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20040519