ATE321068T1 - Alterungsschutztetrapeptid, dieses enthaltende pharmazeutische zusammensetzungen und seine verwendung - Google Patents
Alterungsschutztetrapeptid, dieses enthaltende pharmazeutische zusammensetzungen und seine verwendungInfo
- Publication number
- ATE321068T1 ATE321068T1 AT00905499T AT00905499T ATE321068T1 AT E321068 T1 ATE321068 T1 AT E321068T1 AT 00905499 T AT00905499 T AT 00905499T AT 00905499 T AT00905499 T AT 00905499T AT E321068 T1 ATE321068 T1 AT E321068T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrapeptide
- seq
- proposed
- substance
- glu
- Prior art date
Links
- 230000003712 anti-aging effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 3
- 230000002398 geroprotective effect Effects 0.000 abstract 2
- 230000000144 pharmacologic effect Effects 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 206010063493 Premature ageing Diseases 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-O triethylammonium ion Chemical compound CC[NH+](CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-O 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU99108841/14A RU2157233C1 (ru) | 1999-05-11 | 1999-05-11 | Тетрапептид, обладающий геропротекторной активностью, фармакологическое средство на его основе и способ его применения |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321068T1 true ATE321068T1 (de) | 2006-04-15 |
Family
ID=20219149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00905499T ATE321068T1 (de) | 1999-05-11 | 2000-01-20 | Alterungsschutztetrapeptid, dieses enthaltende pharmazeutische zusammensetzungen und seine verwendung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6727227B1 (https=) |
| EP (1) | EP1179008B1 (https=) |
| JP (1) | JP3902406B2 (https=) |
| AT (1) | ATE321068T1 (https=) |
| AU (1) | AU769847C (https=) |
| CA (1) | CA2373128C (https=) |
| DE (1) | DE60026826T2 (https=) |
| ES (1) | ES2259998T3 (https=) |
| IL (2) | IL146432A0 (https=) |
| RU (1) | RU2157233C1 (https=) |
| WO (1) | WO2000068255A2 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050227925A1 (en) * | 2004-04-08 | 2005-10-13 | Robbert Benner | Compositions capable of reducing elevated blood urea concentration |
| US6921751B1 (en) * | 1998-05-20 | 2005-07-26 | Erasmus Universiteit Rotterdam | Immunoregulator |
| US20030220258A1 (en) * | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of ischemic events |
| US20040202645A1 (en) * | 2003-04-08 | 2004-10-14 | Khan Nisar Ahmed | Administration of gene-regulatory peptides |
| EP1138692A1 (en) | 2000-03-29 | 2001-10-04 | Erasmus Universiteit Rotterdam | Fragments of human chorionic gonadotropin (hcg) as immunoregulator |
| US8680059B2 (en) * | 1998-05-20 | 2014-03-25 | Biotempt B.V. | Oligopeptide acetate and formulations thereof |
| US6844315B2 (en) * | 1998-05-20 | 2005-01-18 | Erasmus Universiteit Rotterdam | Immunoregulator |
| US7175679B2 (en) * | 2001-03-29 | 2007-02-13 | Biotempt B.V. | Oligopeptide treatment of NF-κB mediated inflammation |
| USRE43279E1 (en) | 2000-03-29 | 2012-03-27 | Biotemp B.V. | Compositions capable of reducing elevated blood urea concentration |
| US7576174B2 (en) * | 2000-03-29 | 2009-08-18 | Biotempt B.V. | Compositions capable of reducing elevated blood urea concentration |
| EP1300418A1 (en) * | 2001-10-04 | 2003-04-09 | Erasmus Universiteit Rotterdam | Gene regulation by oligopeptides |
| US7358330B2 (en) * | 2001-03-29 | 2008-04-15 | Biotempt B.V. | Immunoregulatory compositions |
| RU2161501C1 (ru) * | 2000-06-29 | 2001-01-10 | Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" | Способ получения пептидов, обладающих тканеспецифической активностью, и фармацевтические композиции на их основе |
| WO2002090380A1 (en) * | 2001-04-17 | 2002-11-14 | Sankt-Peterburgskaya Obschestvennaya Organizatsiya 'institut Bioregulyatsii I Gerontologii Czo Ramn' | Tetrapeptide stimulating the retinal function and the method of its application |
| US7501391B2 (en) | 2001-12-21 | 2009-03-10 | Biotempt B.V. | Treatment of transplant survival |
| US7786084B2 (en) * | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
| US20040013661A1 (en) * | 2001-12-21 | 2004-01-22 | Gert Wensvoort | Stratification |
| US20030224995A1 (en) * | 2001-12-21 | 2003-12-04 | Khan Nisar Ahmed | Treatment of burns |
| US7560433B2 (en) * | 2001-12-21 | 2009-07-14 | Biotempt B.V. | Treatment of multiple sclerosis (MS) |
| US20080318871A1 (en) * | 2001-12-21 | 2008-12-25 | Khan Nisar A | Treatment of neurological disorders |
| US20030220257A1 (en) * | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of trauma |
| US20030220261A1 (en) * | 2001-12-21 | 2003-11-27 | Khan Nisar Ahmed | Treatment of iatrogenic disease |
| US20080242837A1 (en) * | 2001-12-21 | 2008-10-02 | Khan Nisar A | Peptide compositions |
| US7517529B2 (en) * | 2003-04-08 | 2009-04-14 | Biotempt B.V. | Treatment of type I diabetes |
| RU2257910C1 (ru) * | 2003-12-25 | 2005-08-10 | Институт физиологически активных веществ Российской Академии Наук (ИФАВ РАН) | Растительные экстракты, обладающие геропротекторной активностью и средство на их основе |
| RU2257909C1 (ru) * | 2003-12-25 | 2005-08-10 | Институт физиологически активных веществ Российской Академии Наук (ИФАВ РАН) | Концентрат побегов черники и композиции на его основе, обладающие геропротекторной активностью |
| US20090227505A1 (en) * | 2004-01-07 | 2009-09-10 | Biotempt B.V. | Methods and uses for protein breakdown products |
| RU2255756C1 (ru) * | 2004-06-22 | 2005-07-10 | Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" | Пептидное соединение, восстанавливающее функцию миокарда |
| RU2255757C1 (ru) * | 2004-06-22 | 2005-07-10 | Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" | Пептидное соединение, восстанавливающее функцию органов дыхания |
| RU2297215C2 (ru) * | 2005-02-21 | 2007-04-20 | Государственное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет им. акад. И.П. Павлова" МЗ РФ | Антиоксидантное средство для лечения катаракты |
| JP4846799B2 (ja) * | 2005-07-05 | 2011-12-28 | バイオテンプト ベー．フェー． | 腫瘍の治療 |
| EP1864692A1 (en) * | 2006-06-07 | 2007-12-12 | Biotempt B.V. | Use of peptides for the control of radiation injury |
| RU2295970C1 (ru) * | 2006-05-23 | 2007-03-27 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, повышающий резистентность капилляров, фармацевтическая композиция на его основе и способ ее применения |
| RU2304444C1 (ru) * | 2006-05-23 | 2007-08-20 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, обладающий стресспротекторным действием, фармацевтическая композиция на его основе и способ ее применения |
| RU2301074C1 (ru) * | 2006-05-30 | 2007-06-20 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, обладающий иммуногеропротекторным действием, фармацевтическая композиция на его основе и способ ее применения |
| RU2301678C1 (ru) * | 2006-05-30 | 2007-06-27 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, стимулирующий регенерацию нейронов центральной нервной системы, фармацевтическая композиция на его основе и способ ее применения |
| DK2120991T3 (da) * | 2007-02-12 | 2014-04-28 | Biotempt Bv | Behandling af traumatisk blødning med korte oligopeptider |
| RU2464816C1 (ru) * | 2011-04-14 | 2012-10-27 | Общество с ограниченной ответственностью "Вилави" | Композиция биологически активных веществ, обладающая геропротекторной активностью, и способ комплексной коррекции возрастных изменений гормонального баланса, функций эпифиза и антиоксидантного статуса, включающий введение указанной композиции |
| JP7137745B2 (ja) * | 2015-05-22 | 2022-09-15 | ズィ・エイツー・ミルク・カンパニー・リミテッド | ベータカゼインａ２および抗酸化能 |
| CA3175267A1 (en) * | 2020-04-15 | 2021-10-21 | Anton MALYSHEV | Synthetic peptides for modulating the metabotropic glutamate receptor 5 |
| KR102841388B1 (ko) * | 2022-08-30 | 2025-08-01 | 주식회사 제이포셀 | 항노화 펩타이드 및 황기 추출물을 포함하는 항노화 화장료 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH078273A (ja) * | 1993-06-14 | 1995-01-13 | Kurabo Ind Ltd | 接着性動物細胞の無血清培養法 |
| JPH0851980A (ja) * | 1994-08-11 | 1996-02-27 | Asahi Glass Co Ltd | 合成遺伝子およびこれを用いた癌転移阻害活性を有するペプチドの製造方法 |
| RU2099078C1 (ru) * | 1994-12-08 | 1997-12-20 | Акционерное общество закрытого типа "КОМКОН" | Средство, обладающее антистрессовым, стресспротекторным, ноотропным, антиалкогольным и антинаркотическим действием, способы профилактики и лечения с его использованием |
| RU2112512C1 (ru) * | 1995-09-22 | 1998-06-10 | Иванов Евгений Васильевич | Биологичеcки активная пищевая добавка "глутапирон", обладающая антиканцерогенным и геропротекторным действием |
| GB2348426B (en) * | 1997-04-03 | 2001-06-27 | California Inst Of Techn | Enzyme-mediated modification of fibrin for tissue engineering |
-
1999
- 1999-05-11 RU RU99108841/14A patent/RU2157233C1/ru not_active IP Right Cessation
-
2000
- 2000-01-20 AU AU27034/00A patent/AU769847C/en not_active Ceased
- 2000-01-20 WO PCT/RU2000/000012 patent/WO2000068255A2/en not_active Ceased
- 2000-01-20 IL IL14643200A patent/IL146432A0/xx active IP Right Grant
- 2000-01-20 DE DE60026826T patent/DE60026826T2/de not_active Expired - Lifetime
- 2000-01-20 US US09/959,852 patent/US6727227B1/en not_active Expired - Fee Related
- 2000-01-20 JP JP2000616229A patent/JP3902406B2/ja not_active Expired - Fee Related
- 2000-01-20 CA CA002373128A patent/CA2373128C/en not_active Expired - Fee Related
- 2000-01-20 AT AT00905499T patent/ATE321068T1/de active
- 2000-01-20 EP EP00905499A patent/EP1179008B1/en not_active Expired - Lifetime
- 2000-01-20 ES ES00905499T patent/ES2259998T3/es not_active Expired - Lifetime
-
2001
- 2001-11-11 IL IL146432A patent/IL146432A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003526622A (ja) | 2003-09-09 |
| ES2259998T3 (es) | 2006-11-01 |
| EP1179008A2 (en) | 2002-02-13 |
| AU2703400A (en) | 2000-11-21 |
| CA2373128A1 (en) | 2000-11-16 |
| DE60026826D1 (de) | 2006-05-11 |
| IL146432A0 (en) | 2002-07-25 |
| WO2000068255A2 (en) | 2000-11-16 |
| CA2373128C (en) | 2007-03-13 |
| RU2157233C1 (ru) | 2000-10-10 |
| EP1179008B1 (en) | 2006-03-22 |
| WO2000068255A3 (en) | 2001-06-14 |
| JP3902406B2 (ja) | 2007-04-04 |
| AU769847C (en) | 2005-02-17 |
| AU769847B2 (en) | 2004-02-05 |
| IL146432A (en) | 2007-06-03 |
| DE60026826T2 (de) | 2007-04-12 |
| US6727227B1 (en) | 2004-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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