AU745845B2 - Potassium channel inhibitors - Google Patents
Potassium channel inhibitors Download PDFInfo
- Publication number
- AU745845B2 AU745845B2 AU22419/99A AU2241999A AU745845B2 AU 745845 B2 AU745845 B2 AU 745845B2 AU 22419/99 A AU22419/99 A AU 22419/99A AU 2241999 A AU2241999 A AU 2241999A AU 745845 B2 AU745845 B2 AU 745845B2
- Authority
- AU
- Australia
- Prior art keywords
- optionally substituted
- alkyl
- alkylene
- heterocyclyl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 108020001213 potassium channel Proteins 0.000 title claims abstract description 90
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- 229940095064 tartrate Drugs 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 125000002769 thiazolinyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 125000001425 triazolyl group Chemical group 0.000 description 1
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 1
- 125000003774 valeryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/28—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Magnetic Heads (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Sorption Type Refrigeration Machines (AREA)
- Seasonings (AREA)
- External Artificial Organs (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7271998P | 1998-01-27 | 1998-01-27 | |
| US60/072719 | 1998-01-27 | ||
| PCT/US1999/001663 WO1999037607A1 (en) | 1998-01-27 | 1999-01-27 | Potassium channel inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2241999A AU2241999A (en) | 1999-08-09 |
| AU745845B2 true AU745845B2 (en) | 2002-04-11 |
Family
ID=22109343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU22419/99A Ceased AU745845B2 (en) | 1998-01-27 | 1999-01-27 | Potassium channel inhibitors |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6333337B1 (enExample) |
| EP (1) | EP1051394B1 (enExample) |
| JP (1) | JP2002501041A (enExample) |
| KR (1) | KR20010034377A (enExample) |
| CN (1) | CN1294577A (enExample) |
| AT (1) | ATE265426T1 (enExample) |
| AU (1) | AU745845B2 (enExample) |
| BR (1) | BR9907236A (enExample) |
| CA (1) | CA2317457A1 (enExample) |
| DE (1) | DE69916792D1 (enExample) |
| HU (1) | HUP0101269A3 (enExample) |
| ID (1) | ID25853A (enExample) |
| IL (1) | IL137219A0 (enExample) |
| NO (1) | NO20003600L (enExample) |
| NZ (1) | NZ505666A (enExample) |
| PL (1) | PL341859A1 (enExample) |
| RU (1) | RU2218330C2 (enExample) |
| TR (1) | TR200002191T2 (enExample) |
| TW (1) | TW542823B (enExample) |
| WO (1) | WO1999037607A1 (enExample) |
| ZA (1) | ZA99550B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6333349B1 (en) * | 1997-02-26 | 2001-12-25 | Aventis Pharma Deutschland Gmbh | Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them |
| EP1109544A4 (en) | 1998-09-01 | 2004-10-27 | Bristol Myers Squibb Co | POTASSIUM CHANNEL INHIBITORS AND THEIR METHOD OF USE |
| CA2385047A1 (en) * | 1999-09-22 | 2001-03-29 | Ann H. Cornell-Bell | Uses of kappa-conotoxin pviia |
| AU781365B2 (en) * | 1999-12-21 | 2005-05-19 | Icagen, Inc. | Potassium channel inhibitors |
| US6566380B2 (en) * | 2000-07-25 | 2003-05-20 | Icagen, Inc. | Potassium channel inhibitors |
| US6620849B2 (en) * | 2000-07-26 | 2003-09-16 | Icafen, Inc. | Potassium channel inhibitors |
| DE10059418A1 (de) | 2000-11-30 | 2002-06-20 | Aventis Pharma Gmbh | Ortho, meta-substituierte Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| DE10060807A1 (de) * | 2000-12-07 | 2002-06-20 | Aventis Pharma Gmbh | Ortho, ortho-substituierte stickstoffhaltige Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| DE10061876A1 (de) * | 2000-12-12 | 2002-06-20 | Aventis Pharma Gmbh | Arylierte Furan- und Thiophencarbonsäureamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| US6849634B2 (en) | 2000-12-21 | 2005-02-01 | Icagen | Potassium channel inhibitors |
| DE10121003A1 (de) | 2001-04-28 | 2002-12-19 | Aventis Pharma Gmbh | Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| CN1630707A (zh) | 2002-02-12 | 2005-06-22 | 色雷特康公司 | 用于快速改变传感器周围溶液环境的系统与方法 |
| US7470518B2 (en) | 2002-02-12 | 2008-12-30 | Cellectricon Ab | Systems and method for rapidly changing the solution environment around sensors |
| US20030199578A1 (en) * | 2002-04-19 | 2003-10-23 | Turner Sean C. | Naphthalene amides as potassium channel openers |
| AU2003229734B2 (en) * | 2002-05-08 | 2009-02-19 | Pila Pharma Ab | Hydroxy tetrahydro-naphthalenylurea derivatives |
| JP4422034B2 (ja) * | 2002-12-06 | 2010-02-24 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | テトラヒドロ−ナフタレン誘導体 |
| ATE404531T1 (de) * | 2002-12-09 | 2008-08-15 | Xention Ltd | Tetrahydronaphtalen-derivate als vanilloid- rezeptor-antagonisten |
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| JP4638438B2 (ja) | 2003-10-08 | 2011-02-23 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | テトラヒドロナフタレン誘導体類、それらの生成方法及び抗−炎症剤としてのそれらの使用 |
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
| DE102005017316A1 (de) * | 2005-04-14 | 2006-10-19 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| GB0525164D0 (en) | 2005-12-09 | 2006-01-18 | Xention Discovery Ltd | Compounds |
| EP1834948A1 (de) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| JP2009536156A (ja) * | 2006-04-14 | 2009-10-08 | ノバルティス アクチエンゲゼルシャフト | ヘッジホッグ経路関連障害の処置におけるビアリールカルボキサミドの使用 |
| DE102006019589A1 (de) * | 2006-04-27 | 2007-10-31 | Sanofi-Aventis Deutschland Gmbh | Inhibitoren des TASK-1 und Task-3 Ionenkanals |
| AU2007288253B2 (en) * | 2006-08-23 | 2013-05-02 | Xenon Pharmaceuticals Inc. | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
| BRPI0719590A2 (pt) * | 2006-11-28 | 2014-01-21 | Valeant Pharmaceuticals Int | Análogos de retigabina 1,4 diamino bicíclica como modulares de canal de potássio |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815784D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB201105659D0 (en) | 2011-04-01 | 2011-05-18 | Xention Ltd | Compounds |
| NO3175985T3 (enExample) | 2011-07-01 | 2018-04-28 | ||
| US20150045305A1 (en) | 2012-01-27 | 2015-02-12 | Gilead Sciences, Inc. | Combination therapies using late sodium ion channel blockers and potassium ion channel blockers |
| IL291332B2 (en) | 2021-10-27 | 2025-10-01 | Shanghai Zhimeng Biopharma Inc | Potassium channel blocker, method of preparation and uses |
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| GB1479544A (en) * | 1974-02-07 | 1977-07-13 | American Cyanamid Co | 1,2,3,4-tetrahydro-1-naphthylurea derivatives their preparation and their use |
| US5631275A (en) * | 1993-12-30 | 1997-05-20 | Hoechst Aktiengesellschaft | Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds |
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| US4005140A (en) | 1974-02-07 | 1977-01-25 | American Cyanamid Company | Ureidotetralin compounds |
| US3953506A (en) | 1974-02-07 | 1976-04-27 | American Cyanamid Company | Ureidotetralin compounds |
| GB8707123D0 (en) | 1987-03-25 | 1987-04-29 | Pfizer Ltd | Antiarrhythmic agents |
| US5006512A (en) | 1987-10-02 | 1991-04-09 | Tsuyoshi Ohnishi | Therapeutic usages of inhibitors for a potassium efflux channel |
| IL88314A (en) | 1987-11-18 | 1994-05-30 | Tanabe Seiyaku Co | Sulphonylamino indane derivatives, their preparation and pharmaceutical compositions containing them |
| PT89205B (pt) | 1987-12-14 | 1993-06-30 | Beecham Group Plc | Processo para a preparacao de derivados de indano |
| US5242947A (en) | 1988-02-10 | 1993-09-07 | New York University | Use of polyamines as ionic-channel regulating agents |
| DE3818245A1 (de) | 1988-05-28 | 1989-12-07 | Hoechst Ag | Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln |
| DK0476016T3 (da) * | 1989-05-31 | 1999-07-05 | Upjohn Co | CNS-aktive 8-heterocyclyl-2-aminotetralin-derivater |
| US5215985A (en) | 1990-07-20 | 1993-06-01 | E. R. Squibb & Sons, Inc. | Method for treating ischemic insult to neurons employing an ATP-sensitive potassium channel blocker |
| ATE167473T1 (de) | 1990-08-20 | 1998-07-15 | Eisai Co Ltd | Sulfonamid-derivate |
| US5401848A (en) | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
| US5310932A (en) | 1991-04-15 | 1994-05-10 | E. R. Squibb & Sons, Inc. | Chromanyl substituted indole potassium channel openers |
| US5234947A (en) | 1991-11-07 | 1993-08-10 | New York University | Potassium channel activating compounds and methods of use thereof |
| US5356775A (en) | 1992-07-29 | 1994-10-18 | Brigham & Women's Hospital | Primary structure for functional expression from complementary DNA of a mammalian ATP-sensitive potassium channel |
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| US5453421A (en) | 1992-09-11 | 1995-09-26 | E. R. Squibb & Sons, Inc. | Aryl and heterocyclic substituted propenamide derivatives |
| US5374643A (en) | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
| DE4302051A1 (de) | 1993-01-26 | 1994-07-28 | Thomae Gmbh Dr K | 5-gliedrige Heterocyclen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| GB9309716D0 (en) | 1993-05-12 | 1993-06-23 | Zeneca Ltd | Heterocyclic derivatives |
| US5401758A (en) | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| FR2717805B1 (fr) | 1994-03-28 | 1996-05-10 | Rhone Poulenc Rorer Sa | Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant . |
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| ZA96211B (en) | 1995-01-12 | 1996-07-26 | Teva Pharma | Compositions containing and methods of using 1- aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
| WO1996036596A1 (en) | 1995-05-19 | 1996-11-21 | Chiroscience Limited | 3,4-disubstituted-phenylsulphonamides and their therapeutic use |
| DK0874625T3 (da) | 1996-01-22 | 2005-06-20 | Lilly Co Eli | Indanderivater til antipsykotiske præparater |
| US6083986A (en) | 1996-07-26 | 2000-07-04 | Icagen, Inc. | Potassium channel inhibitors |
| US6048877A (en) | 1997-02-21 | 2000-04-11 | Bristol-Myers Squibb Company | Tetralone derivatives as antiarrhythmic agents |
-
1999
- 1999-01-13 US US09/229,315 patent/US6333337B1/en not_active Expired - Fee Related
- 1999-01-26 ZA ZA9900550A patent/ZA99550B/xx unknown
- 1999-01-27 AT AT99902443T patent/ATE265426T1/de not_active IP Right Cessation
- 1999-01-27 HU HU0101269A patent/HUP0101269A3/hu unknown
- 1999-01-27 NZ NZ505666A patent/NZ505666A/xx unknown
- 1999-01-27 RU RU2000122451/04A patent/RU2218330C2/ru not_active IP Right Cessation
- 1999-01-27 TR TR2000/02191T patent/TR200002191T2/xx unknown
- 1999-01-27 IL IL13721999A patent/IL137219A0/xx unknown
- 1999-01-27 KR KR1020007008128A patent/KR20010034377A/ko not_active Withdrawn
- 1999-01-27 BR BR9907236-0A patent/BR9907236A/pt not_active IP Right Cessation
- 1999-01-27 AU AU22419/99A patent/AU745845B2/en not_active Ceased
- 1999-01-27 WO PCT/US1999/001663 patent/WO1999037607A1/en not_active Ceased
- 1999-01-27 CA CA002317457A patent/CA2317457A1/en not_active Abandoned
- 1999-01-27 CN CN99804373A patent/CN1294577A/zh active Pending
- 1999-01-27 EP EP99902443A patent/EP1051394B1/en not_active Expired - Lifetime
- 1999-01-27 PL PL99341859A patent/PL341859A1/xx not_active Application Discontinuation
- 1999-01-27 DE DE69916792T patent/DE69916792D1/de not_active Expired - Lifetime
- 1999-01-27 ID IDW20001654A patent/ID25853A/id unknown
- 1999-01-27 JP JP2000528531A patent/JP2002501041A/ja active Pending
- 1999-01-27 TW TW088101240A patent/TW542823B/zh not_active IP Right Cessation
-
2000
- 2000-07-13 NO NO20003600A patent/NO20003600L/no unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1479544A (en) * | 1974-02-07 | 1977-07-13 | American Cyanamid Co | 1,2,3,4-tetrahydro-1-naphthylurea derivatives their preparation and their use |
| US5631275A (en) * | 1993-12-30 | 1997-05-20 | Hoechst Aktiengesellschaft | Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010034377A (ko) | 2001-04-25 |
| PL341859A1 (en) | 2001-05-07 |
| NZ505666A (en) | 2002-11-26 |
| HUP0101269A3 (en) | 2003-01-28 |
| ZA99550B (en) | 1999-07-26 |
| DE69916792D1 (de) | 2004-06-03 |
| AU2241999A (en) | 1999-08-09 |
| JP2002501041A (ja) | 2002-01-15 |
| IL137219A0 (en) | 2001-07-24 |
| TR200002191T2 (tr) | 2000-11-21 |
| CN1294577A (zh) | 2001-05-09 |
| NO20003600D0 (no) | 2000-07-13 |
| NO20003600L (no) | 2000-09-26 |
| EP1051394B1 (en) | 2004-04-28 |
| HUP0101269A1 (hu) | 2001-10-28 |
| ID25853A (id) | 2000-11-09 |
| EP1051394A1 (en) | 2000-11-15 |
| BR9907236A (pt) | 2002-01-22 |
| WO1999037607A1 (en) | 1999-07-29 |
| TW542823B (en) | 2003-07-21 |
| ATE265426T1 (de) | 2004-05-15 |
| RU2218330C2 (ru) | 2003-12-10 |
| CA2317457A1 (en) | 1999-07-29 |
| US6333337B1 (en) | 2001-12-25 |
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