AU736701B2 - Assaying nucleotides in solution using PNA probes - Google Patents

Assaying nucleotides in solution using PNA probes Download PDF

Info

Publication number
AU736701B2
AU736701B2 AU65135/98A AU6513598A AU736701B2 AU 736701 B2 AU736701 B2 AU 736701B2 AU 65135/98 A AU65135/98 A AU 65135/98A AU 6513598 A AU6513598 A AU 6513598A AU 736701 B2 AU736701 B2 AU 736701B2
Authority
AU
Australia
Prior art keywords
nucleotide sequence
intensity
detecting
probe
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU65135/98A
Other languages
English (en)
Other versions
AU6513598A (en
Inventor
Eileen Xiao-Feng Nie
Yuan Min Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ingeneus Corp
Original Assignee
Lorne Park Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/870,370 external-priority patent/US6060242A/en
Application filed by Lorne Park Research Inc filed Critical Lorne Park Research Inc
Publication of AU6513598A publication Critical patent/AU6513598A/en
Application granted granted Critical
Publication of AU736701B2 publication Critical patent/AU736701B2/en
Assigned to INGENEUS CORPORATION reassignment INGENEUS CORPORATION Alteration of Name(s) in Register under S187 Assignors: LORNE PARK RESEARCH, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU65135/98A 1997-02-27 1998-02-23 Assaying nucleotides in solution using PNA probes Ceased AU736701B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US80790197A 1997-02-27 1997-02-27
US08/807901 1997-02-27
US08/870,370 US6060242A (en) 1997-02-27 1997-06-06 PNA diagnostic methods
US08/870370 1997-06-06
PCT/IB1998/000521 WO1998038334A1 (en) 1997-02-27 1998-02-23 Assaying nucleotides in solution using pna probes

Publications (2)

Publication Number Publication Date
AU6513598A AU6513598A (en) 1998-09-18
AU736701B2 true AU736701B2 (en) 2001-08-02

Family

ID=27123055

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65135/98A Ceased AU736701B2 (en) 1997-02-27 1998-02-23 Assaying nucleotides in solution using PNA probes

Country Status (13)

Country Link
EP (1) EP0975800B1 (enExample)
JP (1) JP4110223B2 (enExample)
AT (1) ATE241018T1 (enExample)
AU (1) AU736701B2 (enExample)
CA (1) CA2282704C (enExample)
CY (1) CY2406B1 (enExample)
DE (1) DE69814848T2 (enExample)
DK (1) DK0975800T3 (enExample)
ES (1) ES2202821T3 (enExample)
IN (1) IN188176B (enExample)
PT (1) PT975800E (enExample)
TW (1) TW389791B (enExample)
WO (1) WO1998038334A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2288760T3 (es) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
US6251591B1 (en) 1997-02-27 2001-06-26 Lorne Park Research, Inc. Quantitative method for detecting nucleotide concentration
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
EP1536023B1 (en) * 1998-12-08 2008-03-19 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
US6441152B1 (en) 1998-12-08 2002-08-27 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
US6656692B2 (en) * 1999-12-21 2003-12-02 Ingeneus Corporation Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
JP2003527075A (ja) * 1999-03-25 2003-09-16 ハイセック,インコーポレーテッド ハイブリダイゼーションによる配列分析のための、溶液ベースの方法
US6265170B1 (en) * 2000-01-24 2001-07-24 Ingeneus Corporation Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions
US7220541B2 (en) * 2000-01-24 2007-05-22 Ingeneus, Inc. Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7264925B2 (en) 2000-08-30 2007-09-04 Avi Biopharma, Inc. Method for analysis of oligonucleotide analogs
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
JP4377689B2 (ja) 2001-10-15 2009-12-02 バイオアレイ ソリューションズ リミテッド 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析
US7810380B2 (en) 2003-03-25 2010-10-12 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US7041453B2 (en) 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
AU2004276761B2 (en) 2003-09-22 2009-12-24 Bioarray Solutions, Ltd. Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
EP1678495A4 (en) * 2003-10-20 2007-06-27 Univ California TRANSDUCTION SYSTEMS IN THE NANOMASSIC STATION FOR DETECTING MOLECULAR INTERACTIONS
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
ES2546743B1 (es) 2014-03-28 2016-07-07 Institut D'investigació Biomèdica De Bellvitge (Idibell) Marcadores mitocondriales de enfermedades neurodegenerativas
BR112017005121A2 (pt) 2014-09-23 2018-07-31 Tearlab Res Inc sistemas e métodos para integração de coleta de lágrima microfluídica e análise de fluxo lateral de analitos de interesse.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024652A1 (de) * 1992-05-22 1993-12-09 Cristoph Cremer Verfahren zur präparierung und hybridisierung von spezifischen proben

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0232967B1 (en) * 1986-01-10 1993-04-28 Amoco Corporation Competitive homogeneous assay
WO1992018650A1 (en) * 1991-04-11 1992-10-29 Baxter Diagnostics Inc. Detection of dna/rna by fluorescence polarization
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
JPH11512617A (ja) * 1995-10-06 1999-11-02 パーセプテイブ・バイオシステムズ・インコーポレイテツド ペプチド核酸プローブを用いるハイブリダイゼーション分析のための方法、装置及びキット

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024652A1 (de) * 1992-05-22 1993-12-09 Cristoph Cremer Verfahren zur präparierung und hybridisierung von spezifischen proben

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CARLSSON ET AL (1996) NATURE VOL. 380, P207 *

Also Published As

Publication number Publication date
JP2001514497A (ja) 2001-09-11
TW389791B (en) 2000-05-11
JP4110223B2 (ja) 2008-07-02
DE69814848D1 (de) 2003-06-26
AU6513598A (en) 1998-09-18
WO1998038334A1 (en) 1998-09-03
ATE241018T1 (de) 2003-06-15
IN188176B (enExample) 2002-08-31
DE69814848T2 (de) 2004-05-06
EP0975800A1 (en) 2000-02-02
CA2282704C (en) 2007-11-13
DK0975800T3 (da) 2003-09-22
PT975800E (pt) 2003-10-31
ES2202821T3 (es) 2004-04-01
CY2406B1 (en) 2004-09-10
CA2282704A1 (en) 1998-09-03
EP0975800B1 (en) 2003-05-21

Similar Documents

Publication Publication Date Title
US6060242A (en) PNA diagnostic methods
AU736701B2 (en) Assaying nucleotides in solution using PNA probes
AU730865B2 (en) Assaying nucleotides in solution using a fluorescent intensity quenching effect
US6046004A (en) Solution hybridization of nucleic acids with antisense probes having modified backbones
EP1078100B1 (en) Quantitative method for detecting nucleotide concentration
AU703951B2 (en) Detection of mismatches by resolvase cleavage on a solid support
JP2005525787A (ja) プローブとの相互作用による遺伝子ハプロタイプの検出方法
KR101720483B1 (ko) 뱀장어 종 판별용 펩티드핵산(pna) 프로브 세트 및 이를 이용한 뱀장어 종 판별 방법
KR101922598B1 (ko) 실시간 중합효소연쇄반응을 이용하여 rnf213 유전자의 돌연변이를 원인으로 하는 질병을 진단하기 위한 조성물 및 이의 이용
KR100617427B1 (ko) 다양한 조건하의 다중 측정에 의한 생중합체 결합의 균일분석 방법
CA1313633C (en) Purification of polymorphic components of complex genomes
WO1993018178A1 (en) DIAGNOSIS OF β-THALASSEMIA USING A MULTIPLEX AMPLIFICATION REFRACTORY MUTATION SYSTEM
Corley-Smith et al. Efficient detection of DNA polymorphisms by fluorescent RAPD analysis
US20240158839A1 (en) Methods for in situ sequencing
JPH06261758A (ja) マラリアの検出
US7074567B2 (en) Assay for human DNA for gender determination
CN103298951A (zh) 变异型dna的检测方法

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: INGENEUS CORPORATION

Free format text: FORMER OWNER WAS: LORNE PARK RESEARCH, INC.