AU721942B2 - Use of K-252A derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction - Google Patents
Use of K-252A derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction Download PDFInfo
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- AU721942B2 AU721942B2 AU34090/97A AU3409097A AU721942B2 AU 721942 B2 AU721942 B2 AU 721942B2 AU 34090/97 A AU34090/97 A AU 34090/97A AU 3409097 A AU3409097 A AU 3409097A AU 721942 B2 AU721942 B2 AU 721942B2
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Landscapes
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| PCT/US1997/010898 WO1997049406A1 (en) | 1996-06-25 | 1997-06-24 | Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction |
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| AU35345/00A Division AU3534500A (en) | 1996-06-25 | 2000-05-17 | Use of k-252a derivative for the treatment of peripheral or central nerve disorders, ... |
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| US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
| US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
| CA2345295C (en) | 1998-09-25 | 2009-12-15 | Cephalon, Inc. | Use of fused pyrrolocarbazoles in preventing/treating damage to sensory hair cells and cochlear neurons |
| MXPA01003761A (es) | 1998-10-13 | 2003-07-21 | Kyowa Hakko Kogyo Kk | Agente para tratar oftalmopatia. |
| JP2000290184A (ja) * | 1999-04-01 | 2000-10-17 | Kyowa Hakko Kogyo Co Ltd | 経鼻投与製剤 |
| CA2396165C (en) * | 2000-01-14 | 2011-01-04 | John F. Hunt | Airway alkalinization as therapy for airway diseases |
| AU2001261324A1 (en) * | 2000-05-08 | 2001-11-20 | Psoriasis Research Institute | Psoriasis treatment |
| US7129250B2 (en) | 2000-05-19 | 2006-10-31 | Aegera Therapeutics Inc. | Neuroprotective and anti-proliferative compounds |
| US7018999B2 (en) | 2001-05-16 | 2006-03-28 | Cephalon, Inc. | Methods for the treatment and prevention of pain |
| WO2004058190A2 (en) * | 2002-12-23 | 2004-07-15 | Rinat Neuroscience Corp. | Methods for treating taxol-induced sensory neuropathy |
| PL1606409T3 (pl) | 2003-03-19 | 2011-02-28 | Biogen Ma Inc | Białko wiążące receptor Nogo |
| JP2006520806A (ja) * | 2003-03-20 | 2006-09-14 | ライナット ニューロサイエンス コーポレイション | タキソール誘導性腸障害を処置する方法 |
| TWI324604B (en) * | 2003-06-18 | 2010-05-11 | Novartis Ag | New use of staurosporine derivatives |
| EP1646372A2 (en) * | 2003-07-14 | 2006-04-19 | Decode Genetics EHF. | Methods of diagnosis and treatment for asthma based on haplotype association |
| US20060014165A1 (en) * | 2003-07-14 | 2006-01-19 | Decode Genetics Ehf. | Methods of diagnosis and treatment for asthma and other respiratory diseases based on haplotype association |
| WO2005014003A1 (en) * | 2003-07-23 | 2005-02-17 | Creabilis Therapeutics S.R.L. | Topical use of tyrosine kinase inhibitors of microbial origin to prevent and treat skin disorders characterised by excessive cell proliferation |
| WO2005082920A1 (en) | 2004-02-27 | 2005-09-09 | H. Lundbeck A/S | Crystalline forms of a pharmaceutical compound |
| PL1776136T3 (pl) | 2004-06-24 | 2013-03-29 | Biogen Ma Inc | Leczenie stanów związanych z demielinizacją |
| MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| AR054260A1 (es) * | 2005-04-26 | 2007-06-13 | Rinat Neuroscience Corp | Metodos de tratamiento de enfermedades de la neurona motora inferior y composiciones utilizadas en los mismos |
| SG10201508322SA (en) | 2005-07-08 | 2015-11-27 | Biogen Ma Inc | Sp35 antibodies and uses thereof |
| EP2068866A4 (en) | 2006-07-24 | 2010-04-07 | Biogen Idec Inc | METHODS FOR PROMOTING MYELINIZATION, NEURONAL SURVIVAL AND DIFFERENTIATION OF OLIGODENDROCYTES BY ADMINISTERING SP35 OR TRKA ANTAGONISTS |
| WO2010005570A2 (en) | 2008-07-09 | 2010-01-14 | Biogen Idec Ma Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| MX381731B (es) | 2012-05-14 | 2025-03-13 | Biogen Ma Inc | Antagonistas de proteina que interactua con el receptor nogo 2 que contiene repeticion rica en leucina y dominio de inmunoglobulina (lingo-2) para el tratamiento de afecciones que involucran neuronas motoras. |
| HK1246810A1 (zh) | 2015-01-08 | 2018-09-14 | Biogen Ma Inc. | Lingo-1对抗药及用於治疗脱髓鞘疾病的用途 |
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| EP0303697B1 (en) | 1987-03-09 | 1997-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance k-252 |
| IL86632A0 (en) | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
| US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
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| WO1989007105A1 (fr) | 1988-02-04 | 1989-08-10 | Kyowa Hakko Kogyo Co., Ltd. | Derives de staurosporine |
| DE3835842A1 (de) | 1988-10-21 | 1990-04-26 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
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| JPH0586068A (ja) | 1991-03-04 | 1993-04-06 | Rikagaku Kenkyusho | 新規抗生物質ｒｋ−１４０９、その製造法並びに抗腫瘍剤及び抗炎症剤 |
| WO1993008809A1 (en) | 1991-11-08 | 1993-05-13 | The University Of Southern California | Compositions containing k-252 compounds for potentiation of neurotrophin activity |
| JP2593021B2 (ja) | 1991-12-13 | 1997-03-19 | 伊藤ハム株式会社 | ウシ胚の性の識別方法 |
| RU2045575C1 (ru) * | 1992-01-29 | 1995-10-10 | Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Рекомбинатная плазмидная днк ppr - tgatg - hil - 1 beta - tsr, обеспечивающая синтез рекомбинантного интерлейкина-1 и штамм escherichia coli - продуцент рекомбинантного интерлейкина-1 бета человека |
| US6271242B1 (en) | 1992-02-10 | 2001-08-07 | Bristol-Myers Squibb Co. | Method for treating cancer using a tyrosine protein kinase inhibitor |
| JPH05247055A (ja) | 1992-03-03 | 1993-09-24 | Meiji Seika Kaisha Ltd | スタウロスポリン誘導体及びそれを含有する抗腫瘍効果増強剤 |
| US5344926A (en) | 1992-06-22 | 1994-09-06 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing staurosporine derivatives |
| JPH0673063A (ja) | 1992-06-22 | 1994-03-15 | Kyowa Hakko Kogyo Co Ltd | Ｕｃｎ−０１誘導体 |
| US5621100A (en) | 1992-07-24 | 1997-04-15 | Cephalon, Inc. | K-252a derivatives for treatment of neurological disorders |
| US5461146A (en) * | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
| GB9215921D0 (en) * | 1992-07-27 | 1992-09-09 | Wellcome Found | Anti-inflammatory compounds |
| EP0839814A3 (en) | 1993-05-28 | 1998-09-16 | Cephalon, Inc. | Indolocarbazole derivatives and their use for the treatment of prostate gland disorders |
| JPH08511785A (ja) | 1993-06-17 | 1996-12-10 | チバ−ガイギー アクチェンゲゼルシャフト | プロテインキナーゼｃ阻害剤として有用なインドロカルバゾール |
| WO1995022331A1 (en) * | 1994-02-18 | 1995-08-24 | Cephalon, Inc. | Aqueous indolocarbazole solutions |
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- 1997-06-24 AU AU34090/97A patent/AU721942B2/en not_active Expired
- 1997-06-24 EP EP97930203A patent/EP0912184B1/en not_active Expired - Lifetime
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1998
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2008
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Also Published As
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| EP0912184B1 (en) | 2002-09-25 |
| NO986111L (no) | 1999-02-23 |
| WO1997049406A1 (en) | 1997-12-31 |
| CN1228024A (zh) | 1999-09-08 |
| NO317335B1 (no) | 2004-10-11 |
| CN1108799C (zh) | 2003-05-21 |
| HK1018745A1 (en) | 2000-01-07 |
| ATE224718T1 (de) | 2002-10-15 |
| RU2183959C2 (ru) | 2002-06-27 |
| BR9710693A (pt) | 2000-01-11 |
| ES2184106T3 (es) | 2003-04-01 |
| DE69715862T2 (de) | 2003-04-10 |
| JP4767982B2 (ja) | 2011-09-07 |
| EP0912184A1 (en) | 1999-05-06 |
| DK0912184T3 (da) | 2002-11-25 |
| UA65542C2 (uk) | 2004-04-15 |
| PT912184E (pt) | 2002-12-31 |
| JP2008189676A (ja) | 2008-08-21 |
| US6184217B1 (en) | 2001-02-06 |
| DE69715862D1 (de) | 2002-10-31 |
| NO986111D0 (no) | 1998-12-23 |
| AU3409097A (en) | 1998-01-14 |
| JP2000514420A (ja) | 2000-10-31 |
| NZ333441A (en) | 1999-05-28 |
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