AU709301B2 - New technology for wet granulation - Google Patents

New technology for wet granulation Download PDF

Info

Publication number
AU709301B2
AU709301B2 AU72741/96A AU7274196A AU709301B2 AU 709301 B2 AU709301 B2 AU 709301B2 AU 72741/96 A AU72741/96 A AU 72741/96A AU 7274196 A AU7274196 A AU 7274196A AU 709301 B2 AU709301 B2 AU 709301B2
Authority
AU
Australia
Prior art keywords
active ingredient
solubility
wet granulation
compound
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU72741/96A
Other languages
English (en)
Other versions
AU7274196A (en
Inventor
Simon Bechard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9604277.5A external-priority patent/GB9604277D0/en
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Publication of AU7274196A publication Critical patent/AU7274196A/en
Assigned to MERCK FROSST CANADA & CO. reassignment MERCK FROSST CANADA & CO. Alteration of Name(s) of Applicant(s) under S113 Assignors: MERCK FROSST CANADA INC.
Application granted granted Critical
Publication of AU709301B2 publication Critical patent/AU709301B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AU72741/96A 1995-11-02 1996-10-31 New technology for wet granulation Ceased AU709301B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US616195P 1995-11-02 1995-11-02
US60/006161 1995-11-02
GB9604277 1996-02-29
GBGB9604277.5A GB9604277D0 (en) 1996-02-29 1996-02-29 New technology for wet granulation
PCT/CA1996/000724 WO1997016173A1 (en) 1995-11-02 1996-10-31 New technology for wet granulation

Publications (2)

Publication Number Publication Date
AU7274196A AU7274196A (en) 1997-05-22
AU709301B2 true AU709301B2 (en) 1999-08-26

Family

ID=26308826

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72741/96A Ceased AU709301B2 (en) 1995-11-02 1996-10-31 New technology for wet granulation

Country Status (5)

Country Link
EP (1) EP0859600A1 (ja)
JP (1) JPH11514382A (ja)
AU (1) AU709301B2 (ja)
CA (1) CA2236175A1 (ja)
WO (1) WO1997016173A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148466A (en) * 2001-10-26 2013-04-30 Merck Frosst Canada Ltd Granule formulation
CZ298224B6 (cs) * 2003-04-29 2007-07-25 Pliva Istrazivanje I Razvoj D.O.O. Farmaceutická kompozice obsahující jako úcinnou látku ribavirin a zpusob její výroby
EP1976522B2 (en) 2005-12-30 2019-07-03 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical composition containing montelukast
KR101278572B1 (ko) * 2011-10-18 2013-06-25 주식회사 네비팜 류코트리엔 길항제와 에피나스틴의 복합제제
WO2014012954A1 (en) 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
EP3096760A1 (en) 2014-01-22 2016-11-30 Takeda GmbH Treatment of partly controlled or uncontrolled severe asthma with a pde4 inhibitor (and in combination with a leukotriene modifier)
EP2949321A1 (en) 2014-05-26 2015-12-02 Sanovel Ilac Sanayi ve Ticaret A.S. Multilayer formulations of fexofenadine and montelukast
EP3397285A1 (en) 2016-04-22 2018-11-07 Sanovel Ilac Sanayi ve Ticaret A.S. Tablet formulations of montelukast sodium and rupatadine fumarate
WO2017182641A1 (en) 2016-04-22 2017-10-26 Sanovel Ilac Sanayi Ve Ticaret A.S. Bilayer tablet formulations of montelukast and rupatadine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins

Also Published As

Publication number Publication date
EP0859600A1 (en) 1998-08-26
JPH11514382A (ja) 1999-12-07
CA2236175A1 (en) 1997-05-09
AU7274196A (en) 1997-05-22
WO1997016173A1 (en) 1997-05-09

Similar Documents

Publication Publication Date Title
EP0814782B1 (en) Pharmaceutical composition stabilized with a basic agent
JP3267960B2 (ja) 医薬組成物
US20080102120A1 (en) Solid Pharmaceutical Composition Comprising Valsartan
AU709301B2 (en) New technology for wet granulation
CN113939289A (zh) 一种含有布鲁顿氏酪氨酸激酶抑制剂的口服固体片剂及其制备方法
EP1222922A1 (en) Method for stabilizing benzimidazole compounds
JP4127740B2 (ja) 安定化したベンズイミダゾール系化合物含有組成物
MX2007011119A (es) Composiciones farmaceuticas de amlodipino y benazepril.
JP4709379B2 (ja) レボチロキシンナトリウム含有医薬製剤
EP1765342B9 (en) Pharmaceutical composition comprising amlodipine besilate and lisinopril dihydrate and process for the preparation thereof
JP7094944B2 (ja) ロスバスタチン及びエゼチミブを含む医薬組成物並びにその調製方法
JP2002520296A (ja) 薬剤レボチロキシン製剤
KR20210047234A (ko) 프로톤 펌프 저해제 및 탄산수소나트륨을 포함하는 안정한 약제학적 조성물 및 이의 제조방법
WO2007077135A1 (en) Pharmaceutical composition containing montelukast
EP0952823B1 (en) Stabilized pharmaceutical compositions and process for the preparation thereof
EP2464344A2 (en) Pharmaceutical tablet comprising rosuvastatin calcium
RU2674978C2 (ru) Фармацевтическая композиция N-[5-[2-(3,5-диметоксифенил)этил]-2H-пиразол-3-ил]-4-[(3R,5S)-3,5-диметилпиперазин-1-ил]бензамида
JP2001270827A (ja) ベンズイミダゾール系化合物含有錠剤
CN112057427A (zh) 一种含有布鲁顿氏酪氨酸激酶抑制剂的口服固体片剂及其制备方法
US20090220552A1 (en) Formulations containing pantoprazole free acid and its salts
CA2417764C (en) Highly absorbable solid preparations containing sitafloxacin and tartaric acid
EP1207857A1 (en) Ciprofloxacin containing pharmaceutical composition and process for the preparation thereof
EP1872778A1 (en) Stable pharmaceutical composition with rabeprazole sodium
JP2003104891A (ja) 塩酸シプロフロキサシンの医薬組成物
JP2010047553A (ja) ベンズイミダゾール系薬物を含有する固形医薬組成物

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired