CA2236175A1 - New technology for wet granulation - Google Patents

New technology for wet granulation Download PDF

Info

Publication number
CA2236175A1
CA2236175A1 CA 2236175 CA2236175A CA2236175A1 CA 2236175 A1 CA2236175 A1 CA 2236175A1 CA 2236175 CA2236175 CA 2236175 CA 2236175 A CA2236175 A CA 2236175A CA 2236175 A1 CA2236175 A1 CA 2236175A1
Authority
CA
Canada
Prior art keywords
active ingredient
solubility
electrolyte
compound
wet granulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2236175
Other languages
English (en)
French (fr)
Inventor
Simon Bechard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9604277.5A external-priority patent/GB9604277D0/en
Application filed by Individual filed Critical Individual
Publication of CA2236175A1 publication Critical patent/CA2236175A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
CA 2236175 1995-11-02 1996-10-31 New technology for wet granulation Abandoned CA2236175A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US616195P 1995-11-02 1995-11-02
US60/006,161 1995-11-02
GB9604277.5 1996-02-29
GBGB9604277.5A GB9604277D0 (en) 1996-02-29 1996-02-29 New technology for wet granulation

Publications (1)

Publication Number Publication Date
CA2236175A1 true CA2236175A1 (en) 1997-05-09

Family

ID=26308826

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2236175 Abandoned CA2236175A1 (en) 1995-11-02 1996-10-31 New technology for wet granulation

Country Status (5)

Country Link
EP (1) EP0859600A1 (ja)
JP (1) JPH11514382A (ja)
AU (1) AU709301B2 (ja)
CA (1) CA2236175A1 (ja)
WO (1) WO1997016173A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148466A (en) * 2001-10-26 2013-04-30 Merck Frosst Canada Ltd Granule formulation
CZ298224B6 (cs) * 2003-04-29 2007-07-25 Pliva Istrazivanje I Razvoj D.O.O. Farmaceutická kompozice obsahující jako úcinnou látku ribavirin a zpusob její výroby
EP1976522B2 (en) 2005-12-30 2019-07-03 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical composition containing montelukast
KR101278572B1 (ko) * 2011-10-18 2013-06-25 주식회사 네비팜 류코트리엔 길항제와 에피나스틴의 복합제제
WO2014012954A1 (en) 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
EP3096760A1 (en) 2014-01-22 2016-11-30 Takeda GmbH Treatment of partly controlled or uncontrolled severe asthma with a pde4 inhibitor (and in combination with a leukotriene modifier)
EP2949321A1 (en) 2014-05-26 2015-12-02 Sanovel Ilac Sanayi ve Ticaret A.S. Multilayer formulations of fexofenadine and montelukast
EP3397285A1 (en) 2016-04-22 2018-11-07 Sanovel Ilac Sanayi ve Ticaret A.S. Tablet formulations of montelukast sodium and rupatadine fumarate
WO2017182641A1 (en) 2016-04-22 2017-10-26 Sanovel Ilac Sanayi Ve Ticaret A.S. Bilayer tablet formulations of montelukast and rupatadine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins

Also Published As

Publication number Publication date
EP0859600A1 (en) 1998-08-26
JPH11514382A (ja) 1999-12-07
AU709301B2 (en) 1999-08-26
AU7274196A (en) 1997-05-22
WO1997016173A1 (en) 1997-05-09

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead