AU696429B2 - Bradykinin antagonist peptides incorporating n-substituted glycines - Google Patents

Bradykinin antagonist peptides incorporating n-substituted glycines Download PDF

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Publication number
AU696429B2
AU696429B2 AU19325/95A AU1932595A AU696429B2 AU 696429 B2 AU696429 B2 AU 696429B2 AU 19325/95 A AU19325/95 A AU 19325/95A AU 1932595 A AU1932595 A AU 1932595A AU 696429 B2 AU696429 B2 AU 696429B2
Authority
AU
Australia
Prior art keywords
arg
gly
hyp
ser
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU19325/95A
Other languages
English (en)
Other versions
AU1932595A (en
Inventor
Timothy D. Fitzpatrick
Val S. Goodfellow
Karen G. Kuhlman
Manoj V. Marathe
Eric T Whalley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortech Inc
Original Assignee
Cortech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortech Inc filed Critical Cortech Inc
Publication of AU1932595A publication Critical patent/AU1932595A/en
Application granted granted Critical
Publication of AU696429B2 publication Critical patent/AU696429B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU19325/95A 1994-03-09 1995-03-07 Bradykinin antagonist peptides incorporating n-substituted glycines Ceased AU696429B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20811594A 1994-03-09 1994-03-09
US208115 1994-03-09
PCT/US1995/002399 WO1995024422A1 (en) 1994-03-09 1995-03-07 Bradykinin antagonist peptides incorporating n-substituted glycines

Publications (2)

Publication Number Publication Date
AU1932595A AU1932595A (en) 1995-09-25
AU696429B2 true AU696429B2 (en) 1998-09-10

Family

ID=22773240

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19325/95A Ceased AU696429B2 (en) 1994-03-09 1995-03-07 Bradykinin antagonist peptides incorporating n-substituted glycines

Country Status (12)

Country Link
US (1) US5700779A (enExample)
EP (1) EP0813544B1 (enExample)
JP (1) JPH09511500A (enExample)
KR (1) KR100360639B1 (enExample)
CN (1) CN1150206C (enExample)
AT (1) ATE280777T1 (enExample)
AU (1) AU696429B2 (enExample)
CA (1) CA2184824A1 (enExample)
DE (1) DE69533704D1 (enExample)
TW (1) TW408133B (enExample)
WO (1) WO1995024422A1 (enExample)
ZA (1) ZA951974B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648336A (en) * 1994-11-18 1997-07-15 University Of Colorado Bradykinin antagonist peptides containing indane-substituted amino acids
EP0832106A2 (en) * 1995-06-05 1998-04-01 Cortech, Inc. Compounds having bradykinin antagonistic activity and mu-opioid agonistic activity
US5849863A (en) * 1995-09-08 1998-12-15 University Of Colorado Cytolytic bradykinin antagonists
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
FR2756566B1 (fr) * 1996-12-04 1999-01-08 Fournier Ind & Sante Peptides agonistes du recepteur b2 de la bradykinine, procede de preparation et utilisation en therapeutique
AU3731400A (en) 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Methods and compositions useful in inhibiting apoptosis
US6849605B1 (en) 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
AU3864000A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
US6489308B1 (en) 1999-03-05 2002-12-03 Trustees Of University Of Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions
US7105172B1 (en) 1999-11-18 2006-09-12 Bolla John D Treatment of rosacea
US6699486B1 (en) 1999-11-18 2004-03-02 Bolla Corporation Treatment or prevention of photoaging and skin cancer
CA2423876C (en) * 2003-04-01 2013-05-28 Universite De Sherbrooke Novel selective bradykinin (bk) b1 peptidic receptor antagonists and uses thereof
US20040220242A1 (en) * 2003-05-02 2004-11-04 Leland Shapiro Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
US7605120B2 (en) * 2003-10-22 2009-10-20 Amgen Inc. Antagonists of the brandykinin B1 receptor
US7932228B2 (en) * 2004-08-19 2011-04-26 Societe de Commercialisation des Produits de la Recherche Applique Socpra Sciences Sante et Humaines S.E.C. Method of treating bone or prostate cancer with selective bradykinin B1 receptor antagonists
JP2008539260A (ja) * 2005-04-25 2008-11-13 アムジエン・インコーポレーテツド ポロゲンを含む生分解性プチド徐放性組成物
US7403325B2 (en) * 2006-05-19 2008-07-22 Xerox Corporation Electrophoretic display device
US8476408B2 (en) * 2008-06-13 2013-07-02 Alize Pharma Sas Unacylated ghrelin and analogs as therapeutic agents for vascular remodeling in diabetic patients and treatment of cardiovascular disease
FR2974182B1 (fr) * 2011-04-14 2013-04-26 Univ Grenoble 1 Diagnostic et traitement de l'angioedeme
CN102295711A (zh) * 2011-08-23 2011-12-28 湖北宝迪农业科技有限公司 从猪肺中提取肝素钠并联产多肽蛋白粉的工艺
WO2013043669A1 (en) * 2011-09-21 2013-03-28 The Board Of Regents Of The University Of Texas System Peptoid compositions for the treatment of alzheimer's disease and polyglutamine expansion disorder
CA3001065A1 (en) 2015-10-14 2017-04-20 Xiaoxi WEI Compositions and methods for reducing ice crystal formation
CN116554267A (zh) * 2022-01-30 2023-08-08 江苏众红生物工程创药研究院有限公司 聚乙二醇修饰的激肽或其变体和药物应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3943189A (en) * 1988-11-24 1990-05-31 Hoechst Aktiengesellschaft Peptides having bradykinin antagonist action
AU2124592A (en) * 1991-08-22 1993-02-25 Hoechst Aktiengesellschaft Pharmaceutical compositions containing bradykinin antagonists for local use on the nose and eyes
WO1993011789A1 (en) * 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55500520A (enExample) * 1978-07-18 1980-08-14
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
ES2123556T3 (es) * 1991-04-19 1999-01-16 Scios Nova Inc Peptidos de tipo bradiquinina.
TW258739B (enExample) * 1992-04-04 1995-10-01 Hoechst Ag
CA2171446C (en) * 1993-09-09 2004-11-23 Donald James Kyle Pseudo- and non-peptide bradykinin receptor antagonists

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3943189A (en) * 1988-11-24 1990-05-31 Hoechst Aktiengesellschaft Peptides having bradykinin antagonist action
AU2124592A (en) * 1991-08-22 1993-02-25 Hoechst Aktiengesellschaft Pharmaceutical compositions containing bradykinin antagonists for local use on the nose and eyes
WO1993011789A1 (en) * 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides

Also Published As

Publication number Publication date
EP0813544A1 (en) 1997-12-29
WO1995024422A1 (en) 1995-09-14
US5700779A (en) 1997-12-23
ZA951974B (en) 1995-12-11
ATE280777T1 (de) 2004-11-15
TW408133B (en) 2000-10-11
JPH09511500A (ja) 1997-11-18
CN1148393A (zh) 1997-04-23
DE69533704D1 (de) 2004-12-02
EP0813544B1 (en) 2004-10-27
KR100360639B1 (ko) 2003-01-30
EP0813544A4 (enExample) 1998-01-07
CN1150206C (zh) 2004-05-19
AU1932595A (en) 1995-09-25
CA2184824A1 (en) 1995-09-14

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