AU681178B2 - Agonists and antagonists of human interleukin-10 - Google Patents
Agonists and antagonists of human interleukin-10 Download PDFInfo
- Publication number
- AU681178B2 AU681178B2 AU73996/94A AU7399694A AU681178B2 AU 681178 B2 AU681178 B2 AU 681178B2 AU 73996/94 A AU73996/94 A AU 73996/94A AU 7399694 A AU7399694 A AU 7399694A AU 681178 B2 AU681178 B2 AU 681178B2
- Authority
- AU
- Australia
- Prior art keywords
- amino acid
- human
- antagonist
- acid residues
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9894393A | 1993-07-26 | 1993-07-26 | |
US098943 | 1993-07-26 | ||
PCT/US1994/008052 WO1995003411A1 (en) | 1993-07-26 | 1994-07-22 | Agonists and antagonists of human interleukin-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU7399694A AU7399694A (en) | 1995-02-20 |
AU681178B2 true AU681178B2 (en) | 1997-08-21 |
Family
ID=22271670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU73996/94A Ceased AU681178B2 (en) | 1993-07-26 | 1994-07-22 | Agonists and antagonists of human interleukin-10 |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0711346A1 (hu) |
JP (1) | JPH08507930A (hu) |
KR (1) | KR960704041A (hu) |
CN (1) | CN1127529A (hu) |
AU (1) | AU681178B2 (hu) |
CA (1) | CA2168110A1 (hu) |
CZ (1) | CZ23396A3 (hu) |
FI (1) | FI960353A0 (hu) |
HU (1) | HUT73463A (hu) |
IL (1) | IL110413A0 (hu) |
NO (1) | NO960309L (hu) |
NZ (1) | NZ269663A (hu) |
PL (1) | PL312718A1 (hu) |
SG (1) | SG43798A1 (hu) |
SK (2) | SK150596A3 (hu) |
WO (1) | WO1995003411A1 (hu) |
ZA (1) | ZA945434B (hu) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6159937A (en) * | 1994-07-05 | 2000-12-12 | Steeno Research Group A/S | Immunomodulators |
GB2304047A (en) | 1995-08-09 | 1997-03-12 | Univ Manchester | Pharmaceutical compositions containing cytokines |
AUPN481295A0 (en) * | 1995-08-16 | 1995-09-07 | Medvet Science Pty. Ltd. | Agonists of haemopoietic growth factors |
WO1997026278A1 (en) | 1996-01-18 | 1997-07-24 | Steeno Research Group A/S | Synthetic il-10 analogues |
DE19851675A1 (de) * | 1998-11-10 | 2000-05-11 | Bayer Ag | Menschliche Interleukin-10 Mutantenproteine |
CN1981868A (zh) | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗-cd20在b细胞淋巴瘤治疗中的联合应用 |
ES2367891T3 (es) | 2000-09-29 | 2011-11-10 | Schering Corporation | Interleucina-10 pegilada. |
US7261882B2 (en) | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
EP1712241A1 (en) | 2005-04-15 | 2006-10-18 | Centre National De La Recherche Scientifique (Cnrs) | Composition for treating cancer adapted for intra-tumoral administration and uses thereof |
EP1885863B1 (en) | 2005-05-31 | 2014-11-19 | The Regents of the University of Colorado, a body corporate | Methods for delivering genes |
EP2066336B1 (en) | 2006-09-28 | 2012-09-19 | Merck Sharp & Dohme Corp. | Use of pegylated il-10 to treat cancer |
PL2344540T3 (pl) | 2008-10-02 | 2018-05-30 | Aptevo Research And Development Llc | Białka wiążące wiele celów antagonistyczne względem cd86 |
NO2379115T3 (hu) | 2008-12-17 | 2018-03-24 | ||
ES2683844T3 (es) | 2011-11-08 | 2018-09-28 | Umc Utrecht Holding B.V. | Proteína de fusión que comprende una interleucina 4 e interleucina 10 |
CN105209054A (zh) | 2013-04-18 | 2015-12-30 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
EP2989240A4 (en) * | 2013-04-24 | 2016-10-19 | Armo Biosciences Inc | INTERLEUKIN-10 COMPOSITIONS AND USES THEREOF |
WO2014204816A2 (en) | 2013-06-17 | 2014-12-24 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
EP3038642A4 (en) | 2013-08-30 | 2017-01-18 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
WO2015070060A1 (en) | 2013-11-11 | 2015-05-14 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
WO2015187295A2 (en) | 2014-06-02 | 2015-12-10 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
CA2963989A1 (en) | 2014-10-14 | 2016-04-21 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
EP3209320B1 (en) | 2014-10-22 | 2023-03-08 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
CN107847583A (zh) | 2015-05-28 | 2018-03-27 | 阿尔莫生物科技股份有限公司 | 用于治疗癌症的聚乙二醇化白细胞介素‑10 |
AU2016312510A1 (en) | 2015-08-25 | 2018-03-08 | Armo Biosciences, Inc. | Methods of using Interleukin-10 for treating diseases and disorders |
CN114144194A (zh) | 2019-04-19 | 2022-03-04 | 斯纳凯恩制药私人有限责任公司 | 一种包含il13的融合蛋白 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01113229A (ja) * | 1987-10-27 | 1989-05-01 | Inahata Kenkyusho:Kk | 多孔質ハニカム構成材 |
IL94878A (en) * | 1989-06-28 | 2003-01-12 | Schering Corp | Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same |
KR100271197B1 (ko) * | 1991-08-06 | 2000-11-01 | 둘락 노먼 씨. | 인터루킨-10동족체또는길항제를포함하는내독소-또는초항원유도된독성치료용의약제학적조성물 |
-
1994
- 1994-07-22 CA CA002168110A patent/CA2168110A1/en not_active Abandoned
- 1994-07-22 JP JP7505238A patent/JPH08507930A/ja active Pending
- 1994-07-22 SG SG1996000969A patent/SG43798A1/en unknown
- 1994-07-22 SK SK1505-96A patent/SK150596A3/sk unknown
- 1994-07-22 ZA ZA945434A patent/ZA945434B/xx unknown
- 1994-07-22 KR KR1019960700358A patent/KR960704041A/ko not_active Application Discontinuation
- 1994-07-22 HU HU9503983A patent/HUT73463A/hu unknown
- 1994-07-22 IL IL11041394A patent/IL110413A0/xx unknown
- 1994-07-22 EP EP94923956A patent/EP0711346A1/en not_active Withdrawn
- 1994-07-22 CN CN94192880A patent/CN1127529A/zh active Pending
- 1994-07-22 AU AU73996/94A patent/AU681178B2/en not_active Ceased
- 1994-07-22 WO PCT/US1994/008052 patent/WO1995003411A1/en not_active Application Discontinuation
- 1994-07-22 CZ CZ96233A patent/CZ23396A3/cs unknown
- 1994-07-22 SK SK83-96A patent/SK8396A3/sk unknown
- 1994-07-22 NZ NZ269663A patent/NZ269663A/en unknown
- 1994-07-22 PL PL94312718A patent/PL312718A1/xx unknown
-
1996
- 1996-01-25 NO NO960309A patent/NO960309L/no unknown
- 1996-01-26 FI FI960353A patent/FI960353A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
WO1995003411A1 (en) | 1995-02-02 |
NZ269663A (en) | 1997-09-22 |
AU7399694A (en) | 1995-02-20 |
SG43798A1 (en) | 1997-11-14 |
JPH08507930A (ja) | 1996-08-27 |
NO960309D0 (no) | 1996-01-25 |
KR960704041A (ko) | 1996-08-31 |
IL110413A0 (en) | 1994-10-21 |
SK8396A3 (en) | 1997-03-05 |
FI960353A (fi) | 1996-01-26 |
NO960309L (no) | 1996-01-25 |
CZ23396A3 (en) | 1996-05-15 |
ZA945434B (en) | 1995-01-23 |
SK150596A3 (en) | 1997-04-09 |
HUT73463A (en) | 1996-08-28 |
CA2168110A1 (en) | 1995-02-02 |
CN1127529A (zh) | 1996-07-24 |
HU9503983D0 (en) | 1996-03-28 |
EP0711346A1 (en) | 1996-05-15 |
PL312718A1 (en) | 1996-05-13 |
FI960353A0 (fi) | 1996-01-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |