AU677789B2 - Biocompatible polymer conjugates - Google Patents

Biocompatible polymer conjugates Download PDF

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Publication number
AU677789B2
AU677789B2 AU46620/93A AU4662093A AU677789B2 AU 677789 B2 AU677789 B2 AU 677789B2 AU 46620/93 A AU46620/93 A AU 46620/93A AU 4662093 A AU4662093 A AU 4662093A AU 677789 B2 AU677789 B2 AU 677789B2
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AU
Australia
Prior art keywords
collagen
peg
conjugate
polymer
biocompatible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU46620/93A
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English (en)
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AU4662093A (en
Inventor
Hanne Bentz
Richard A. Berg
Ramon A. Burns Jr.
Ramesh Damani
Frank Delustro
Louis Fries
Kimberly Mccullough
Alan S. Michaels
Woonza Rhee
Donald G. Wallace
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Collagen Aesthetics Inc
Original Assignee
Collagen Corp
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Filing date
Publication date
Priority claimed from US07/907,518 external-priority patent/US5324775A/en
Application filed by Collagen Corp filed Critical Collagen Corp
Publication of AU4662093A publication Critical patent/AU4662093A/en
Application granted granted Critical
Publication of AU677789B2 publication Critical patent/AU677789B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
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    • C07ORGANIC CHEMISTRY
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    • C07KPEPTIDES
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    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
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    • C08H1/00Macromolecular products derived from proteins
    • C08H1/06Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
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    • C09JADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
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    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • C08L2666/00Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02Organic macromolecular compounds, natural resins, waxes or and bituminous materials

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  • Medicinal Chemistry (AREA)
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  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials Engineering (AREA)
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  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Composite Materials (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
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AU46620/93A 1992-07-02 1993-07-01 Biocompatible polymer conjugates Ceased AU677789B2 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US907518 1992-07-02
US07/907,518 US5324775A (en) 1988-11-21 1992-07-02 Biologically inert, biocompatible-polymer conjugates
US07/922,541 US5328955A (en) 1988-11-21 1992-07-30 Collagen-polymer conjugates
US922541 1992-07-30
US98493392A 1992-12-02 1992-12-02
US07/985,680 US5292802A (en) 1988-11-21 1992-12-02 Collagen-polymer tubes for use in vascular surgery
US984197 1992-12-02
US07/984,197 US5308889A (en) 1988-11-21 1992-12-02 Dehydrated collagen-polymer strings
US984933 1992-12-02
US2503293A 1993-03-02 1993-03-02
US025032 1993-03-02
PCT/US1993/006292 WO1994001483A1 (fr) 1992-07-02 1993-07-01 Conjugues polymeres biocompatibles
US985680 2001-11-05

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JPH08502082A (ja) 1996-03-05

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