AU649696B2 - Preparation process of sustained release compositions and the compositions thus obtained - Google Patents
Preparation process of sustained release compositions and the compositions thus obtained Download PDFInfo
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- AU649696B2 AU649696B2 AU81466/91A AU8146691A AU649696B2 AU 649696 B2 AU649696 B2 AU 649696B2 AU 81466/91 A AU81466/91 A AU 81466/91A AU 8146691 A AU8146691 A AU 8146691A AU 649696 B2 AU649696 B2 AU 649696B2
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- UGMCXQCYOVCMTB-UHFFFAOYSA-K dihydroxy(stearato)aluminium Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[Al](O)O UGMCXQCYOVCMTB-UHFFFAOYSA-K 0.000 description 1
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- 229960002897 heparin Drugs 0.000 description 1
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- 229960000890 hydrocortisone Drugs 0.000 description 1
- XZZXIYZZBJDEEP-UHFFFAOYSA-N imipramine hydrochloride Chemical compound [Cl-].C1CC2=CC=CC=C2N(CCC[NH+](C)C)C2=CC=CC=C21 XZZXIYZZBJDEEP-UHFFFAOYSA-N 0.000 description 1
- 229960002102 imipramine hydrochloride Drugs 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
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- NCYVXEGFNDZQCU-UHFFFAOYSA-N nikethamide Chemical compound CCN(CC)C(=O)C1=CC=CN=C1 NCYVXEGFNDZQCU-UHFFFAOYSA-N 0.000 description 1
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- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
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- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 description 1
- 229960002695 phenobarbital Drugs 0.000 description 1
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- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 description 1
- 229960003147 reserpine Drugs 0.000 description 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 description 1
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- 239000008159 sesame oil Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Biological Depolymerization Polymers (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Glanulating (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909016885A GB9016885D0 (en) | 1990-08-01 | 1990-08-01 | Sustained release pharmaceutical compositions |
| GB9016885 | 1990-08-01 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU59393/94A Division AU666808B2 (en) | 1990-08-01 | 1994-04-11 | Sustained release compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU8146691A AU8146691A (en) | 1992-02-06 |
| AU649696B2 true AU649696B2 (en) | 1994-06-02 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU81466/91A Ceased AU649696B2 (en) | 1990-08-01 | 1991-07-31 | Preparation process of sustained release compositions and the compositions thus obtained |
| AU59393/94A Ceased AU666808B2 (en) | 1990-08-01 | 1994-04-11 | Sustained release compositions |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU59393/94A Ceased AU666808B2 (en) | 1990-08-01 | 1994-04-11 | Sustained release compositions |
Country Status (30)
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| JP (1) | JP2818704B2 (OSRAM) |
| KR (1) | KR920003962A (OSRAM) |
| AT (1) | AT396425B (OSRAM) |
| AU (2) | AU649696B2 (OSRAM) |
| BE (1) | BE1004772A3 (OSRAM) |
| CA (1) | CA2048270C (OSRAM) |
| CH (1) | CH682715A5 (OSRAM) |
| DE (1) | DE4125542A1 (OSRAM) |
| DK (1) | DK175756B1 (OSRAM) |
| ES (1) | ES2046083B1 (OSRAM) |
| FI (1) | FI104149B (OSRAM) |
| FR (1) | FR2665360B1 (OSRAM) |
| GB (1) | GB9016885D0 (OSRAM) |
| GR (1) | GR1001512B (OSRAM) |
| HK (1) | HK33294A (OSRAM) |
| IE (1) | IE65124B1 (OSRAM) |
| IN (1) | IN178446B (OSRAM) |
| IT (1) | IT1251788B (OSRAM) |
| LU (1) | LU87982A1 (OSRAM) |
| MA (1) | MA22245A1 (OSRAM) |
| MY (1) | MY107500A (OSRAM) |
| NL (1) | NL194637C (OSRAM) |
| NO (1) | NO300158B1 (OSRAM) |
| NZ (1) | NZ238981A (OSRAM) |
| OA (1) | OA09387A (OSRAM) |
| PT (1) | PT98497B (OSRAM) |
| SE (1) | SE505734C2 (OSRAM) |
| TN (1) | TNSN91067A1 (OSRAM) |
| ZA (1) | ZA915565B (OSRAM) |
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| US5569467A (en) * | 1993-05-15 | 1996-10-29 | Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) | Process for the preparation of microballs and microballs thus obtained |
| GB9310030D0 (en) * | 1993-05-15 | 1993-06-30 | Scras | Dry processed particles and process for the preparation of the same |
| DE69529054T2 (de) * | 1994-02-28 | 2003-08-21 | Nanopharm Ag | System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung |
| US5980945A (en) * | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
| DE19604744A1 (de) | 1996-02-09 | 1997-08-14 | Henkel Kgaa | Technische Di-/Triglyceridgemische |
| DE19617137C1 (de) * | 1996-04-29 | 1997-02-27 | Henkel Kgaa | Verwendung von Copolymerestern für die Herstellung von Mikrosphären |
| AU4571097A (en) * | 1996-10-09 | 1998-05-05 | Takeda Chemical Industries Ltd. | A method for producing a microparticle |
| TW577759B (en) * | 1997-04-18 | 2004-03-01 | Ipsen Pharma Biotech | Sustained release compositions in the form of microcapsules or implants and the process for their preparation |
| EP1079967A4 (en) | 1998-04-13 | 2003-07-23 | Luminex Corp | LIQUID MARKING USING FLUORESCENT MICROPARTICLES |
| MEP19408A (en) * | 1998-12-16 | 2010-06-10 | Aventis Pharma Inc | Biodegradable polymer encapsulated serotonin receptor antagonist and method for preparing the same |
| AU5644400A (en) * | 1999-09-24 | 2001-03-29 | Rohm And Haas Company | Pellet compositions |
| US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
| US7374782B2 (en) | 2000-10-27 | 2008-05-20 | Baxter International Inc. | Production of microspheres |
| US20050233945A1 (en) * | 2003-07-18 | 2005-10-20 | Larry Brown | Methods for fabrication, uses and compositions of small spherical particles of insulin prepared by controlled phase separation |
| DE60226613D1 (de) * | 2001-08-16 | 2008-06-26 | Baxter Int | Darreichungsformen welche mikropartikel und treibgas enthalten |
| US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
| FR2848113B1 (fr) * | 2002-12-04 | 2005-02-25 | Oreal | Stabilisation de principes actifs aromatiques par des polymeres aromatiques |
| US20040166077A1 (en) * | 2002-12-04 | 2004-08-26 | L'oreal | Process for treating keratin materials with aromatic active principles |
| US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
| US20070092452A1 (en) * | 2003-07-18 | 2007-04-26 | Julia Rashba-Step | Methods for fabrication, uses, compositions of inhalable spherical particles |
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| US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
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| WO2005112885A2 (en) * | 2004-05-12 | 2005-12-01 | Baxter International Inc. | Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1 |
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| EP1885335A1 (en) * | 2005-04-27 | 2008-02-13 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Surface-modified microparticles and methods of forming and using the same |
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| CA2702340C (en) | 2006-10-12 | 2014-12-16 | The University Of Queensland | Compositions and methods for modulating immune responses |
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| US3567650A (en) * | 1969-02-14 | 1971-03-02 | Ncr Co | Method of making microscopic capsules |
| US4010125A (en) * | 1975-06-12 | 1977-03-01 | Schally Andrew Victor | [D-Trp6 ]-LH-RH and intermediates therefor |
| US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| IN167096B (OSRAM) * | 1985-04-04 | 1990-09-01 | Akzo Nv | |
| US4666705A (en) * | 1985-06-03 | 1987-05-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| GB8628728D0 (en) * | 1986-12-02 | 1987-01-07 | Euro Celtique Sa | Spheroids |
| GB8705083D0 (en) * | 1987-03-04 | 1987-04-08 | Euro Celtique Sa | Spheroids |
| EP0366058A3 (en) * | 1988-10-27 | 1991-03-20 | Abbott Laboratories | Controlled-release delivery device, method for producing device, and method of using device |
-
1990
- 1990-08-01 GB GB909016885A patent/GB9016885D0/en active Pending
-
1991
- 1991-07-15 IN IN627DE1991 patent/IN178446B/en unknown
- 1991-07-15 IT ITMI911953A patent/IT1251788B/it active IP Right Grant
- 1991-07-16 NZ NZ238981A patent/NZ238981A/en not_active IP Right Cessation
- 1991-07-16 ZA ZA915565A patent/ZA915565B/xx unknown
- 1991-07-19 BE BE9100685A patent/BE1004772A3/fr not_active IP Right Cessation
- 1991-07-22 MY MYPI91001315A patent/MY107500A/en unknown
- 1991-07-22 CH CH2179/91A patent/CH682715A5/fr not_active IP Right Cessation
- 1991-07-23 US US07/734,493 patent/US5213812A/en not_active Expired - Lifetime
- 1991-07-25 LU LU87982A patent/LU87982A1/fr unknown
- 1991-07-26 SE SE9102249A patent/SE505734C2/sv unknown
- 1991-07-30 NL NL9101306A patent/NL194637C/nl not_active IP Right Cessation
- 1991-07-30 GR GR910100330A patent/GR1001512B/el not_active IP Right Cessation
- 1991-07-30 PT PT98497A patent/PT98497B/pt not_active IP Right Cessation
- 1991-07-30 TN TNTNSN91067A patent/TNSN91067A1/fr unknown
- 1991-07-30 ES ES09101785A patent/ES2046083B1/es not_active Expired - Fee Related
- 1991-07-31 DK DK199101418A patent/DK175756B1/da not_active IP Right Cessation
- 1991-07-31 FI FI913646A patent/FI104149B/fi active
- 1991-07-31 IE IE270091A patent/IE65124B1/en not_active IP Right Cessation
- 1991-07-31 KR KR1019910013237A patent/KR920003962A/ko not_active Ceased
- 1991-07-31 AU AU81466/91A patent/AU649696B2/en not_active Ceased
- 1991-07-31 NO NO912986A patent/NO300158B1/no not_active IP Right Cessation
- 1991-07-31 AT AT0152591A patent/AT396425B/de not_active IP Right Cessation
- 1991-08-01 MA MA22524A patent/MA22245A1/fr unknown
- 1991-08-01 JP JP3192950A patent/JP2818704B2/ja not_active Expired - Fee Related
- 1991-08-01 CA CA002048270A patent/CA2048270C/en not_active Expired - Lifetime
- 1991-08-01 OA OA60055A patent/OA09387A/xx unknown
- 1991-08-01 FR FR9109773A patent/FR2665360B1/fr not_active Expired - Fee Related
- 1991-08-01 DE DE4125542A patent/DE4125542A1/de not_active Withdrawn
-
1994
- 1994-04-11 AU AU59393/94A patent/AU666808B2/en not_active Ceased
- 1994-04-14 HK HK33294A patent/HK33294A/xx not_active IP Right Cessation
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