AU605235B2 - Alkylmelatonins - Google Patents

Alkylmelatonins Download PDF

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Publication number
AU605235B2
AU605235B2 AU10979/88A AU1097988A AU605235B2 AU 605235 B2 AU605235 B2 AU 605235B2 AU 10979/88 A AU10979/88 A AU 10979/88A AU 1097988 A AU1097988 A AU 1097988A AU 605235 B2 AU605235 B2 AU 605235B2
Authority
AU
Australia
Prior art keywords
compound
formula
alkyl
methyl
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU10979/88A
Other languages
English (en)
Other versions
AU1097988A (en
Inventor
Michael Edward Flaugh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU1097988A publication Critical patent/AU1097988A/en
Application granted granted Critical
Publication of AU605235B2 publication Critical patent/AU605235B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU10979/88A 1987-02-02 1988-01-29 Alkylmelatonins Expired AU605235B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1025987A 1987-02-02 1987-02-02
US010259 1987-02-02

Publications (2)

Publication Number Publication Date
AU1097988A AU1097988A (en) 1988-08-04
AU605235B2 true AU605235B2 (en) 1991-01-10

Family

ID=21744889

Family Applications (1)

Application Number Title Priority Date Filing Date
AU10979/88A Expired AU605235B2 (en) 1987-02-02 1988-01-29 Alkylmelatonins

Country Status (19)

Country Link
EP (1) EP0281242B1 (enExample)
JP (1) JP2585341B2 (enExample)
KR (1) KR960004859B1 (enExample)
CN (1) CN1017426B (enExample)
AT (1) ATE79373T1 (enExample)
AU (1) AU605235B2 (enExample)
CA (1) CA1299174C (enExample)
DE (1) DE3873562T2 (enExample)
DK (2) DK44688A (enExample)
ES (1) ES2042726T3 (enExample)
GR (1) GR3005737T3 (enExample)
HU (1) HU199789B (enExample)
IE (1) IE61511B1 (enExample)
IL (1) IL85189A (enExample)
NZ (1) NZ223293A (enExample)
PH (1) PH25095A (enExample)
PT (1) PT86619B (enExample)
SU (1) SU1553011A3 (enExample)
ZA (1) ZA88498B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2439743A (en) * 1945-10-30 1948-04-13 Samuel M Mcewen Subsoiler and aerator
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
BR9007382A (pt) * 1989-05-17 1992-04-28 Michael Cohen Composicoes e metodos de efetuar a contracepcao
IT1243782B (it) * 1990-08-06 1994-06-28 Maria Francesca Devoto Composizione per il controllo della moltiplicazione di animali vertebrati per mezzo di mangimi od esche contenenti degli agonisti periferici di dopamina
FR2674522B1 (fr) * 1991-03-26 1993-07-16 Lipha Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant.
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
KR101511074B1 (ko) 2007-04-16 2015-04-13 애브비 인코포레이티드 7-치환된 인돌 Ｍｃｌ-1 억제제
JPWO2014010603A1 (ja) 2012-07-10 2016-06-23 アステラス製薬株式会社 腹圧性尿失禁又は混合型尿失禁の治療又は予防用医薬組成物、及び該医薬組成物に含有される化合物のスクリーニング方法
CN104496882A (zh) * 2014-11-29 2015-04-08 湖北金赛药业有限公司 一种褪黑素的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE43725B1 (en) * 1975-10-29 1981-05-06 Lilly Co Eli N-/2-(5-methoxy-6-halo-indol-3-yl)ethyl/-amides,methods for their preparation and their use
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins

Also Published As

Publication number Publication date
EP0281242B1 (en) 1992-08-12
IL85189A0 (en) 1988-07-31
EP0281242A1 (en) 1988-09-07
DE3873562T2 (de) 1993-03-04
CN88100478A (zh) 1988-08-17
DE3873562D1 (de) 1992-09-17
CN1017426B (zh) 1992-07-15
KR880009926A (ko) 1988-10-05
GR3005737T3 (enExample) 1993-06-07
IL85189A (en) 1992-06-21
IE880266L (en) 1988-08-02
ZA88498B (en) 1989-10-25
AU1097988A (en) 1988-08-04
DK44688A (da) 1988-08-03
IE61511B1 (en) 1994-11-16
ATE79373T1 (de) 1992-08-15
ES2042726T3 (es) 1993-12-16
PT86619B (pt) 1991-12-31
HU199789B (en) 1990-03-28
KR960004859B1 (ko) 1996-04-16
PH25095A (en) 1991-02-19
DK44688D0 (da) 1988-01-29
NZ223293A (en) 1990-02-26
PT86619A (pt) 1988-02-01
HUT46662A (en) 1988-11-28
SU1553011A3 (ru) 1990-03-23
DK168434B1 (da) 1994-03-28
JPS63196563A (ja) 1988-08-15
JP2585341B2 (ja) 1997-02-26
CA1299174C (en) 1992-04-21

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