ATE79373T1 - Beta-alkylmelatonine. - Google Patents

Beta-alkylmelatonine.

Info

Publication number
ATE79373T1
ATE79373T1 AT88300767T AT88300767T ATE79373T1 AT E79373 T1 ATE79373 T1 AT E79373T1 AT 88300767 T AT88300767 T AT 88300767T AT 88300767 T AT88300767 T AT 88300767T AT E79373 T1 ATE79373 T1 AT E79373T1
Authority
AT
Austria
Prior art keywords
melatonins
beta alkyl
beta
alkyl
alkylmelatonins
Prior art date
Application number
AT88300767T
Other languages
English (en)
Inventor
Michael Edward Flaugh
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE79373T1 publication Critical patent/ATE79373T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT88300767T 1987-02-02 1988-01-29 Beta-alkylmelatonine. ATE79373T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1025987A 1987-02-02 1987-02-02
EP88300767A EP0281242B1 (de) 1987-02-02 1988-01-29 Beta-Alkylmelatonine

Publications (1)

Publication Number Publication Date
ATE79373T1 true ATE79373T1 (de) 1992-08-15

Family

ID=21744889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88300767T ATE79373T1 (de) 1987-02-02 1988-01-29 Beta-alkylmelatonine.

Country Status (19)

Country Link
EP (1) EP0281242B1 (de)
JP (1) JP2585341B2 (de)
KR (1) KR960004859B1 (de)
CN (1) CN1017426B (de)
AT (1) ATE79373T1 (de)
AU (1) AU605235B2 (de)
CA (1) CA1299174C (de)
DE (1) DE3873562T2 (de)
DK (2) DK44688A (de)
ES (1) ES2042726T3 (de)
GR (1) GR3005737T3 (de)
HU (1) HU199789B (de)
IE (1) IE61511B1 (de)
IL (1) IL85189A (de)
NZ (1) NZ223293A (de)
PH (1) PH25095A (de)
PT (1) PT86619B (de)
SU (1) SU1553011A3 (de)
ZA (1) ZA88498B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2439743A (en) * 1945-10-30 1948-04-13 Samuel M Mcewen Subsoiler and aerator
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
AU644367B2 (en) * 1989-05-17 1993-12-09 Applied Medical Research Ltd Use of melatonin derivatives for effecting contraception
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
IT1243782B (it) * 1990-08-06 1994-06-28 Maria Francesca Devoto Composizione per il controllo della moltiplicazione di animali vertebrati per mezzo di mangimi od esche contenenti degli agonisti periferici di dopamina
FR2674522B1 (fr) * 1991-03-26 1993-07-16 Lipha Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant.
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
US8445679B2 (en) * 2007-04-16 2013-05-21 Abbvie Inc. 7-substituted indole MCL-1 inhibitors
JPWO2014010603A1 (ja) * 2012-07-10 2016-06-23 アステラス製薬株式会社 腹圧性尿失禁又は混合型尿失禁の治療又は予防用医薬組成物、及び該医薬組成物に含有される化合物のスクリーニング方法
CN104496882A (zh) * 2014-11-29 2015-04-08 湖北金赛药业有限公司 一种褪黑素的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE43725B1 (en) * 1975-10-29 1981-05-06 Lilly Co Eli N-/2-(5-methoxy-6-halo-indol-3-yl)ethyl/-amides,methods for their preparation and their use
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins

Also Published As

Publication number Publication date
IL85189A (en) 1992-06-21
JPS63196563A (ja) 1988-08-15
IE880266L (en) 1988-08-02
IL85189A0 (en) 1988-07-31
PT86619B (pt) 1991-12-31
NZ223293A (en) 1990-02-26
AU605235B2 (en) 1991-01-10
DE3873562T2 (de) 1993-03-04
KR960004859B1 (ko) 1996-04-16
SU1553011A3 (ru) 1990-03-23
IE61511B1 (en) 1994-11-16
AU1097988A (en) 1988-08-04
HU199789B (en) 1990-03-28
DK44688A (da) 1988-08-03
CN1017426B (zh) 1992-07-15
CN88100478A (zh) 1988-08-17
PT86619A (pt) 1988-02-01
EP0281242B1 (de) 1992-08-12
PH25095A (en) 1991-02-19
DK168434B1 (da) 1994-03-28
ES2042726T3 (es) 1993-12-16
KR880009926A (ko) 1988-10-05
EP0281242A1 (de) 1988-09-07
CA1299174C (en) 1992-04-21
DE3873562D1 (de) 1992-09-17
JP2585341B2 (ja) 1997-02-26
DK44688D0 (da) 1988-01-29
GR3005737T3 (de) 1993-06-07
HUT46662A (en) 1988-11-28
ZA88498B (en) 1989-10-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time