AU533442B2 - Alkoxyphenylpyrrolidones - Google Patents

Alkoxyphenylpyrrolidones

Info

Publication number
AU533442B2
AU533442B2 AU49440/79A AU4944079A AU533442B2 AU 533442 B2 AU533442 B2 AU 533442B2 AU 49440/79 A AU49440/79 A AU 49440/79A AU 4944079 A AU4944079 A AU 4944079A AU 533442 B2 AU533442 B2 AU 533442B2
Authority
AU
Australia
Prior art keywords
group
pyrrolidone
preparation
methoxy
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU49440/79A
Other languages
English (en)
Other versions
AU4944079A (en
Inventor
Dr. Bernd Muller
Gert Paschelke
Dr. Ralph Schmiechen
Dr. Dieter Seidelmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU4944079A publication Critical patent/AU4944079A/en
Application granted granted Critical
Publication of AU533442B2 publication Critical patent/AU533442B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
AU49440/79A 1978-08-01 1979-08-01 Alkoxyphenylpyrrolidones Ceased AU533442B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782834114 DE2834114A1 (de) 1978-08-01 1978-08-01 Polyalkoxyphenylpyrrolidone iii, verfahren zu ihrer herstellung und ihre verwendung
DE28341142 1978-08-01

Publications (2)

Publication Number Publication Date
AU4944079A AU4944079A (en) 1980-02-07
AU533442B2 true AU533442B2 (en) 1983-11-24

Family

ID=6046151

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49440/79A Ceased AU533442B2 (en) 1978-08-01 1979-08-01 Alkoxyphenylpyrrolidones

Country Status (15)

Country Link
US (1) US4219551A (enExample)
EP (1) EP0008645B1 (enExample)
JP (1) JPS5522686A (enExample)
AT (1) ATE9221T1 (enExample)
AU (1) AU533442B2 (enExample)
CA (1) CA1115701A (enExample)
CS (1) CS225816B2 (enExample)
DD (1) DD145104B3 (enExample)
DE (2) DE2834114A1 (enExample)
DK (1) DK152426C (enExample)
ES (1) ES482917A1 (enExample)
HU (1) HU183103B (enExample)
IE (1) IE48915B1 (enExample)
IL (1) IL57926A (enExample)
SU (1) SU878197A3 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
SE8500573D0 (sv) * 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
JPH0788357B2 (ja) * 1986-10-27 1995-09-27 吉富製薬株式会社 ピペラジン化合物
DE3809031A1 (de) * 1988-03-15 1989-09-28 Schering Ag Neues mittel gegen obstruktive blasenentleerungsstoerung
DE3921593A1 (de) * 1989-06-28 1991-01-10 Schering Ag Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-ester
KR970702276A (ko) * 1994-04-22 1997-05-13 고오사이 아끼오 에테르 화합물 및 그의 용도(ether compound and use thereof)
DE19648011A1 (de) * 1996-11-20 1998-05-28 Bayer Ag Cyclische Imine
MXPA04000565A (es) * 2001-07-19 2005-06-17 Cv Therapeutics Inc Compuestos de piperazina sustituidos y su uso como inhibidores de oxidacion de acidos grasos.
WO2003032981A1 (en) * 2001-10-16 2003-04-24 Memory Pharmaceuticals Corporation 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes
US7696198B2 (en) * 2003-04-16 2010-04-13 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors
US7226930B2 (en) * 2003-04-18 2007-06-05 Memory Pharmaceutical Corporation Phosphodiesterase 4 inhibitors
EP1799673A1 (en) 2004-10-15 2007-06-27 Memory Pharmaceuticals Corporation Pyrazole derivatives as phosphodiesterase 4 inhibitors
WO2006044955A1 (en) * 2004-10-20 2006-04-27 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577415A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-substituted phenoxypyrrolidines
DE2263211A1 (de) * 1972-12-23 1974-07-04 Boehringer Sohn Ingelheim Neue arylpiperazine und verfahren zu ihrer herstellung
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
US4120969A (en) * 1975-09-23 1978-10-17 A. H. Robins Company, Incorporated Heterocyclic analgetic and antidiarrheal compounds
DE2737630A1 (de) * 1977-08-20 1979-03-01 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4096331A (en) * 1976-12-28 1978-06-20 A. H. Robins Company, Incorporated 1-Substituted-3-aminoethoxypyrrolidines

Also Published As

Publication number Publication date
ES482917A1 (es) 1980-04-16
JPS5522686A (en) 1980-02-18
HU183103B (en) 1984-04-28
JPH0371423B2 (enExample) 1991-11-13
DE2967204D1 (en) 1984-10-11
IL57926A (en) 1983-10-31
IE791453L (en) 1980-02-01
DK152426B (da) 1988-02-29
DD145104A5 (de) 1980-11-19
IL57926A0 (en) 1979-11-30
DD145104B3 (de) 1990-07-18
CA1115701A (en) 1982-01-05
EP0008645B1 (de) 1984-09-05
DE2834114A1 (de) 1980-02-14
AU4944079A (en) 1980-02-07
DK323179A (da) 1980-02-02
IE48915B1 (en) 1985-06-12
CS225816B2 (en) 1984-02-13
EP0008645A1 (de) 1980-03-19
DK152426C (da) 1988-08-29
ATE9221T1 (de) 1984-09-15
US4219551A (en) 1980-08-26
SU878197A3 (ru) 1981-10-30

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