AU509956B2 - Thiophenes - Google Patents

Thiophenes

Info

Publication number
AU509956B2
AU509956B2 AU28092/77A AU2809277A AU509956B2 AU 509956 B2 AU509956 B2 AU 509956B2 AU 28092/77 A AU28092/77 A AU 28092/77A AU 2809277 A AU2809277 A AU 2809277A AU 509956 B2 AU509956 B2 AU 509956B2
Authority
AU
Australia
Prior art keywords
amino
carbomethoxy
lower alkyl
formula
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU28092/77A
Other languages
English (en)
Other versions
AU2809277A (en
Inventor
P. N. Pizzolato G. Rouge M. and Uskokovic R Confalone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2809277A publication Critical patent/AU2809277A/en
Application granted granted Critical
Publication of AU509956B2 publication Critical patent/AU509956B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU28092/77A 1976-08-23 1977-08-22 Thiophenes Expired AU509956B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US71685476A 1976-08-23 1976-08-23
US71685376A 1976-08-23 1976-08-23
USUS716853 1976-08-23
USUS716854 1976-08-23
US82052177A 1977-08-01 1977-08-01
USUS820521 1977-08-01

Publications (2)

Publication Number Publication Date
AU2809277A AU2809277A (en) 1979-03-01
AU509956B2 true AU509956B2 (en) 1980-06-05

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28092/77A Expired AU509956B2 (en) 1976-08-23 1977-08-22 Thiophenes

Country Status (21)

Country Link
JP (1) JPS5340755A (enExample)
AR (1) AR222453A1 (enExample)
AT (1) AT359486B (enExample)
AU (1) AU509956B2 (enExample)
BE (1) BE858012A (enExample)
CH (1) CH628628A5 (enExample)
DE (1) DE2737738C2 (enExample)
DK (1) DK150484C (enExample)
ES (1) ES461796A1 (enExample)
FI (1) FI66859C (enExample)
FR (1) FR2365566A1 (enExample)
GB (1) GB1587084A (enExample)
HU (1) HU179484B (enExample)
IE (1) IE45470B1 (enExample)
IL (1) IL52792A (enExample)
IT (1) IT1143757B (enExample)
LU (1) LU78003A1 (enExample)
MC (1) MC1156A1 (enExample)
NL (1) NL7709246A (enExample)
NO (1) NO148673C (enExample)
NZ (1) NZ184981A (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (enExample) * 1981-02-28 1987-08-21
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
DE69435137D1 (de) 1993-05-13 2008-10-16 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
WO1998046588A2 (en) * 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
NZ587261A (en) * 2008-02-29 2012-05-25 Nissan Chemical Ind Ltd Process for producing thiophene compound and intermediate thereof
AR130733A1 (es) 2022-10-14 2025-01-15 Adama Agan Ltd Proceso para la preparación de aminotiofeno sustituido

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene

Also Published As

Publication number Publication date
CH628628A5 (en) 1982-03-15
MC1156A1 (fr) 1978-04-17
NO772917L (no) 1978-02-24
FI772494A7 (fi) 1978-02-24
JPS6121235B2 (enExample) 1986-05-26
GB1587084A (en) 1981-03-25
ATA607477A (de) 1980-04-15
AR222453A1 (es) 1981-05-29
HU179484B (en) 1982-10-28
IL52792A (en) 1981-06-29
FI66859C (fi) 1984-12-10
JPS5340755A (en) 1978-04-13
NZ184981A (en) 1980-08-26
NO148673B (no) 1983-08-15
AT359486B (de) 1980-11-10
ES461796A1 (es) 1978-12-16
FR2365566A1 (fr) 1978-04-21
DE2737738C2 (de) 1987-01-29
NO148673C (no) 1983-11-23
LU78003A1 (enExample) 1978-09-14
BE858012A (fr) 1978-02-22
FR2365566B1 (enExample) 1980-12-26
IE45470B1 (en) 1982-09-08
DK372177A (da) 1978-02-24
DK150484C (da) 1987-10-05
DK150484B (da) 1987-03-09
FI66859B (fi) 1984-08-31
DE2737738A1 (de) 1978-03-09
AU2809277A (en) 1979-03-01
NL7709246A (nl) 1978-02-27
IT1143757B (it) 1986-10-22
IL52792A0 (en) 1977-10-31
IE45470L (en) 1978-02-23

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