AU2907201A - Methods and compositions relating to electrical detection of nucleic acid reactions - Google Patents

Methods and compositions relating to electrical detection of nucleic acid reactions Download PDF

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Publication number
AU2907201A
AU2907201A AU29072/01A AU2907201A AU2907201A AU 2907201 A AU2907201 A AU 2907201A AU 29072/01 A AU29072/01 A AU 29072/01A AU 2907201 A AU2907201 A AU 2907201A AU 2907201 A AU2907201 A AU 2907201A
Authority
AU
Australia
Prior art keywords
microelectrodes
electrode
contact
target molecule
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU29072/01A
Other languages
English (en)
Inventor
Vi-En Choong
Sean Gallagher
Mike Gaskin
Changming Li
George Maracas
Song Shi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Motorola Solutions Inc
Original Assignee
Motorola Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/458,533 external-priority patent/US20020051975A1/en
Priority claimed from US09/459,685 external-priority patent/US6518024B2/en
Application filed by Motorola Inc filed Critical Motorola Inc
Publication of AU2907201A publication Critical patent/AU2907201A/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
AU29072/01A 1999-12-09 2000-12-11 Methods and compositions relating to electrical detection of nucleic acid reactions Abandoned AU2907201A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US45850199A 1999-12-09 1999-12-09
US09/458,533 US20020051975A1 (en) 1999-12-09 1999-12-09 Reporterless genosensors using electrical detection methods
US09458533 1999-12-09
US09458501 1999-12-09
US09459685 1999-12-13
US09/459,685 US6518024B2 (en) 1999-12-13 1999-12-13 Electrochemical detection of single base extension
PCT/US2000/033497 WO2001042508A2 (fr) 1999-12-09 2000-12-11 Procedes et compositions se rapportant a la detection electrique des reactions d'acides nucleiques

Publications (1)

Publication Number Publication Date
AU2907201A true AU2907201A (en) 2001-06-18

Family

ID=27412734

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29072/01A Abandoned AU2907201A (en) 1999-12-09 2000-12-11 Methods and compositions relating to electrical detection of nucleic acid reactions

Country Status (5)

Country Link
EP (1) EP1238114A2 (fr)
JP (1) JP2003516165A (fr)
AU (1) AU2907201A (fr)
CA (1) CA2393733A1 (fr)
WO (1) WO2001042508A2 (fr)

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US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
US6824669B1 (en) * 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
GB0118931D0 (en) * 2001-08-02 2001-09-26 Oxford Biosensors Ltd Voltammetric ion-selective biosensor
DE10210051B4 (de) 2002-03-07 2005-10-13 Siemens Ag Vorrichtung zum elektrochemischen Nachweis einer Nukleotidsequenz, Analyse-Kassette für eine solche Vorrichtung und Verfahren zur Herstellung einer solchen Analyse-Kassette
DE10224567B4 (de) 2002-06-03 2014-10-23 Boehringer Ingelheim Vetmedica Gmbh Sensor-Anordnung und Verfahren zum Betreiben einer Sensor-Anordnung
DE10228260A1 (de) * 2002-06-25 2004-01-22 Bayer Ag Methode und Vorrichtung zum impedimetrischen Nachweis eines oder mehrerer Analyten in einer Probe
GB2391867A (en) * 2002-08-13 2004-02-18 Smartbead Technologies Ltd Analysis system using coded supports
KR100858080B1 (ko) 2002-11-12 2008-09-10 삼성전자주식회사 전기적 신호를 측정하는 ｐｃｒ 증폭 산물을 검출하는 방법
AU2003266711A1 (en) * 2002-11-14 2004-06-03 Cosel Co., Ltd. Method of detecting hybridization
DE10259819B4 (de) * 2002-12-19 2006-07-13 Siemens Ag Verfahren zur PCR-Amplifikation und Detektion von Nucleotidsequenzen
US7138121B2 (en) 2003-01-23 2006-11-21 Spangler Brenda D Biosensors utilizing dendrimer-immobilized ligands and there use thereof
AT413214B (de) * 2003-01-24 2005-12-15 Sy Lab Vgmbh Messanordnung und verfahren zur detektion einer dna-sequenz
WO2005001122A2 (fr) * 2003-06-27 2005-01-06 Adnavance Technologies, Inc. Detection electrochimique de liaison d'adn
CA2516647A1 (fr) * 2003-03-05 2004-09-16 University Of Saskatchewan Technologies Inc. Detection de mesappariement d'acides nucleiques
DE10327756B4 (de) * 2003-06-18 2005-12-29 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Verfahren zum Echtzeit-Quantifizieren einer Nukleinsäure
KR100590569B1 (ko) * 2004-02-14 2006-06-15 삼성전자주식회사 실시간 중합효소연쇄반응 검사 방법
US20080227651A1 (en) * 2004-03-25 2008-09-18 Yanxiu Zhou Cyclic voltammetry (CV) for identifying genomic sequence variations and detecting mismatch base pairs, such as single nucleotide polymorphisms
WO2005093418A1 (fr) * 2004-03-26 2005-10-06 Toto, Ltd. Procede de detection specifique de substance de test a l'aide de courant photoelectrique et d'electrodes, cellule de mesure, dispositif de mesure et solution tampon destines a etre utilises a cet effet
SG151333A1 (en) 2004-04-01 2009-04-30 Univ Nanyang Addressable chem/bio chip array
KR100613612B1 (ko) 2004-04-27 2006-08-18 삼성전자주식회사 인덕턴스 소자 및 캐패시턴스 소자를 이용한 바이오결합검출 장치 및 방법
JP2008527999A (ja) 2005-01-21 2008-07-31 ユニバーシティー オブ ロチェスター 長い１本鎖核酸および２本鎖核酸から短い１本鎖核酸を分離するための方法、ならびに関連した生体分子アッセイ法
US20100285601A1 (en) * 2007-09-28 2010-11-11 Agency For Science, Technology And Research Method of electrically detecting a nucleic acid molecule
US9187783B2 (en) 2010-10-04 2015-11-17 Genapsys, Inc. Systems and methods for automated reusable parallel biological reactions
US9184099B2 (en) 2010-10-04 2015-11-10 The Board Of Trustees Of The Leland Stanford Junior University Biosensor devices, systems and methods therefor
US9399217B2 (en) 2010-10-04 2016-07-26 Genapsys, Inc. Chamber free nanoreactor system
US9926596B2 (en) 2011-05-27 2018-03-27 Genapsys, Inc. Systems and methods for genetic and biological analysis
US8585973B2 (en) 2011-05-27 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Nano-sensor array
CN104105797B (zh) 2011-12-01 2016-08-31 吉纳普赛斯股份有限公司 用于高效电子测序与检测的系统和方法
CN105051214B (zh) 2013-03-15 2018-12-28 吉纳普赛斯股份有限公司 用于生物分析的系统和方法
WO2015089238A1 (fr) 2013-12-11 2015-06-18 Genapsys, Inc. Systèmes et procédés d'analyse et d'informatique biologiques
EP3556864B1 (fr) 2014-04-18 2020-12-09 Genapsys, Inc. Procédés et systèmes d'amplification d'acide nucléique
EP3488017A4 (fr) 2016-07-20 2020-02-26 Genapsys Inc. Systèmes et procédés de séquençage d'acides nucléiques
CN111566224A (zh) 2017-09-21 2020-08-21 吉纳普赛斯股份有限公司 用于核酸测序的系统和方法

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US5001048A (en) * 1987-06-05 1991-03-19 Aurthur D. Little, Inc. Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film
CS274231B1 (en) * 1988-12-05 1991-04-11 Jan Rndr Krejci Regenerable enzyme sensor with exchangeable membrane system
US5776672A (en) * 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
US5849486A (en) * 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
IL103674A0 (en) * 1991-11-19 1993-04-04 Houston Advanced Res Center Method and apparatus for molecule detection
RU2041261C1 (ru) * 1993-08-11 1995-08-09 Институт молекулярной биологии им.В.А.Энгельгардта РАН Способ изготовления матрицы для детектирования мисматчей
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US6207369B1 (en) * 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US5981268A (en) * 1997-05-30 1999-11-09 Board Of Trustees, Leland Stanford, Jr. University Hybrid biosensors
JP2001512691A (ja) * 1997-08-12 2001-08-28 ユニバーシティ・オブ・サザン・カリフォルニア イムノアッセイ分析および分子生物学的な過程を調べるための電気化学的レポーターシステム
DE19741716A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung
US6048692A (en) * 1997-10-07 2000-04-11 Motorola, Inc. Sensors for electrically sensing binding events for supported molecular receptors
CA2327525A1 (fr) * 1998-05-06 1999-11-11 Cynthia Bamdad Detection electronique d'acides nucleiques a l'aide de monocouches

Also Published As

Publication number Publication date
EP1238114A2 (fr) 2002-09-11
CA2393733A1 (fr) 2001-06-14
WO2001042508A3 (fr) 2002-03-14
WO2001042508A2 (fr) 2001-06-14
JP2003516165A (ja) 2003-05-13
WO2001042508A9 (fr) 2002-05-30

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