CA2393766A1 - Matrice de biopuces, haute densite, adressable par colonnes et rangees - Google Patents
Matrice de biopuces, haute densite, adressable par colonnes et rangees Download PDFInfo
- Publication number
- CA2393766A1 CA2393766A1 CA002393766A CA2393766A CA2393766A1 CA 2393766 A1 CA2393766 A1 CA 2393766A1 CA 002393766 A CA002393766 A CA 002393766A CA 2393766 A CA2393766 A CA 2393766A CA 2393766 A1 CA2393766 A1 CA 2393766A1
- Authority
- CA
- Canada
- Prior art keywords
- conductive
- electrode
- probes
- target molecule
- impedance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00511—Walls of reactor vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00698—Measurement and control of process parameters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
Abstract
L'invention concerne un procédé et un dispositif comprenant une plate-forme destinée à une matrice de biopuces, haute densité, adressable par colonnes et rangées. On peut utiliser ce dispositif en tant que matrice de biopuces haute densité, dans la détection électronique ou électrochimique d'interactions moléculaires entre des molécules sondes liées à des régions déterminées de la matrice, et des molécules cibles exposées à la matrice.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46450099A | 1999-12-15 | 1999-12-15 | |
US09/464,500 | 1999-12-15 | ||
PCT/US2000/034222 WO2001043870A2 (fr) | 1999-12-15 | 2000-12-14 | Matrice de biopuces, haute densite, adressable par colonnes et rangees |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2393766A1 true CA2393766A1 (fr) | 2001-06-21 |
Family
ID=23844193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002393766A Abandoned CA2393766A1 (fr) | 1999-12-15 | 2000-12-14 | Matrice de biopuces, haute densite, adressable par colonnes et rangees |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1251955A2 (fr) |
JP (1) | JP2003517149A (fr) |
AU (1) | AU2108901A (fr) |
CA (1) | CA2393766A1 (fr) |
WO (1) | WO2001043870A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2492674A1 (fr) | 2011-02-28 | 2012-08-29 | Lexogen GmbH | Réseaux de biocapteurs formé par jonctions d'électrodes fonctionnalisées |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6824669B1 (en) * | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
CA2450109A1 (fr) * | 2001-06-11 | 2003-05-22 | Genorx, Inc. | Detection electronique de molecules biologiques au moyen de fines couches |
US6824974B2 (en) | 2001-06-11 | 2004-11-30 | Genorx, Inc. | Electronic detection of biological molecules using thin layers |
GB2377026A (en) * | 2001-06-29 | 2002-12-31 | Imp College Innovations Ltd | Electrically addressable electrochemical cell array |
DE10145700A1 (de) * | 2001-09-17 | 2003-04-10 | Infineon Technologies Ag | Biochip-Anordnung, Sensor-Anordnung und Verfahren zum Betreiben einer Biochip-Anordnung |
US7074519B2 (en) * | 2001-10-26 | 2006-07-11 | The Regents Of The University Of California | Molehole embedded 3-D crossbar architecture used in electrochemical molecular memory device |
DE10211358B4 (de) * | 2002-03-14 | 2006-10-26 | Siemens Ag | Vertikal-Impedanz-Sensor-Anordnung und Verfahren zum Herstellen einer Vertikal-Impedanz-Sensor-Anordnung |
FR2839783B1 (fr) * | 2002-05-17 | 2004-08-06 | Apibio | Nouvelle disposition des sites de liaison d'une biopuce |
FR2840072B1 (fr) * | 2002-05-24 | 2004-08-06 | Apibio | Biopuce presentant une organisation amelioree |
DE50305588D1 (de) * | 2002-06-24 | 2006-12-14 | Siemens Ag | Biosensor-array und verfahren zum betreiben eines biosensor-arrays |
DE10228124A1 (de) * | 2002-06-24 | 2004-01-29 | Infineon Technologies Ag | Biosensor-Array und Verfahren zum Betreiben eines Biosensor-Arrays |
DE10228125A1 (de) * | 2002-06-24 | 2004-01-22 | Infineon Technologies Ag | Biosensor-Array und Verfahren zum Betreiben eines Biosensor-Arrays |
US6962822B2 (en) | 2002-08-07 | 2005-11-08 | International Business Machines Corporation | Discrete nano-textured structures in biomolecular arrays, and method of use |
EP1548437A4 (fr) * | 2002-09-17 | 2006-06-07 | Olympus Corp | Procede et appareil d'agencement de constituants par reaction de liquide sur une surface de substrat pour la detection d'une substance cible par la reaction de constituants multiples sur substrate et elements utilises dans le procede |
DE10257604A1 (de) * | 2002-12-09 | 2004-07-22 | Axaron Bioscience Ag | Kapazitiver Nachweis von gebundenen Molekülen |
US7138121B2 (en) | 2003-01-23 | 2006-11-21 | Spangler Brenda D | Biosensors utilizing dendrimer-immobilized ligands and there use thereof |
GB2398751A (en) * | 2003-02-28 | 2004-09-01 | Univ Surrey | A dielectrophoretic separation device |
JP2004298783A (ja) * | 2003-03-31 | 2004-10-28 | Kitakyushu Foundation For The Advancement Of Industry Science & Technology | 化学物質分離膜及びその製造方法、並びに化学物質の検出方法及び化学物質検出装置 |
US7399400B2 (en) | 2003-09-30 | 2008-07-15 | Nano-Proprietary, Inc. | Nanobiosensor and carbon nanotube thin film transistors |
EP1682880A1 (fr) | 2003-10-08 | 2006-07-26 | Philips Intellectual Property & Standards GmbH | Capteur d'ondes acoustiques en volume |
JP2007508137A (ja) * | 2003-10-15 | 2007-04-05 | オックスフォード・ジーン・テクノロジー・アイピー・リミテッド | 基板の電気化学的処理 |
US7390622B2 (en) | 2003-10-16 | 2008-06-24 | Hai Kang Life Corporation Limited | Apparatus and methods for detecting nucleic acid in biological samples |
KR101165860B1 (ko) | 2003-10-16 | 2012-07-13 | 하이 캉 라이프 코포레이션 리미티드 | 생물학적 샘플에서 핵산을 검출하는 장치 및 방법 |
US20050244811A1 (en) * | 2003-12-15 | 2005-11-03 | Nano-Proprietary, Inc. | Matrix array nanobiosensor |
DE102004031672A1 (de) | 2004-06-30 | 2006-01-19 | Infineon Technologies Ag | Planar-Sensor-Anordnung, Sensor-Array und Verfahren zum Herstellen einer Planar-Sensor-Anordnung |
JP5041680B2 (ja) | 2005-06-17 | 2012-10-03 | 株式会社ハイペップ研究所 | バイオチップ用基板及びバイオチップ |
JP4635258B2 (ja) * | 2006-03-02 | 2011-02-23 | 独立行政法人産業技術総合研究所 | バイオセンサー |
WO2007107844A1 (fr) | 2006-03-17 | 2007-09-27 | Element Six Limited | Réseau de microélectrode |
US9550185B2 (en) | 2006-11-09 | 2017-01-24 | Asmag-Holding Gmbh | Titer plate with thin-film-light sensor |
AT505688A1 (de) | 2007-09-13 | 2009-03-15 | Nanoident Technologies Ag | Sensormatrix aus halbleiterbauteilen |
JP5176235B2 (ja) * | 2008-07-03 | 2013-04-03 | 国立大学法人東北大学 | 電気化学測定装置 |
GB0821810D0 (en) * | 2008-11-28 | 2009-01-07 | Nanoflex Ltd | Electrode assembly |
DE102011010767A1 (de) * | 2011-02-09 | 2012-08-09 | Forschungszentrum Jülich GmbH | Verfahren zur Herstellung einer Vorrichtung zum Nachweis eines Analyten sowie Vorrichtung und deren Verwendung |
CA3191015A1 (fr) | 2012-02-07 | 2013-08-15 | Vibrant Holdings, Llc | Substrats, reseaux de peptides et procedes |
US10006909B2 (en) | 2012-09-28 | 2018-06-26 | Vibrant Holdings, Llc | Methods, systems, and arrays for biomolecular analysis |
DE102013207779A1 (de) * | 2012-10-23 | 2014-05-15 | Heraeus Precious Metals Gmbh & Co. Kg | Multischichtaufbau mit alternierenden leitenden und nicht leitenden Schichten |
US9523642B2 (en) * | 2012-11-09 | 2016-12-20 | Taiwan Semiconductor Manufacturing Company, Ltd. | Integrated electro-microfluidic probe card, system and method for using the same |
US10286376B2 (en) | 2012-11-14 | 2019-05-14 | Vibrant Holdings, Llc | Substrates, systems, and methods for array synthesis and biomolecular analysis |
EP2956771B1 (fr) * | 2013-02-15 | 2020-04-08 | Vibrant Holdings, LLC | Procédés et compositions pour détection amplifiée d'une électrochimiluminescence |
CN103627788A (zh) * | 2013-08-21 | 2014-03-12 | 中山大学达安基因股份有限公司 | 一种电化学基因传感器生物芯片的制备方法 |
US9498142B2 (en) | 2014-07-03 | 2016-11-22 | Heraeus Deutschland GmbH & Co. KG | Multi-layered structure and method |
WO2016102178A1 (fr) * | 2014-12-23 | 2016-06-30 | Heraeus Sensor Technology Gmbh | Capteur de détection de particules polarisables et/ou électriquement conductrices et procédé de réglage d'un tel capteur |
US20180024023A1 (en) * | 2015-01-29 | 2018-01-25 | Aram Corporation | Liquid sensor |
JP6116080B1 (ja) * | 2016-04-26 | 2017-04-19 | 日本航空電子工業株式会社 | 電気化学測定方法、電気化学測定装置及びトランスデューサ |
US10538808B2 (en) | 2017-05-26 | 2020-01-21 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
KR102423723B1 (ko) * | 2020-08-27 | 2022-07-21 | 성균관대학교산학협력단 | 플라즈모닉 우물 기반 핵산 검출장치 및 롤투롤 공정을 이용한 이의 제조방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6440662B1 (en) * | 1995-12-01 | 2002-08-27 | Innogenetics N.V. | Impedimetric detection system and method of production thereof |
US5727977A (en) * | 1996-03-04 | 1998-03-17 | Motorola, Inc. | Process for manufacturing a field-emission device |
CA2310622A1 (fr) * | 1997-08-08 | 1999-02-18 | California Institute Of Technology | Techniques et systemes de detection d'analysats |
GB9810568D0 (en) * | 1998-05-18 | 1998-07-15 | Imco 1097 Limited | Electrode system |
-
2000
- 2000-12-14 EP EP00984476A patent/EP1251955A2/fr not_active Withdrawn
- 2000-12-14 JP JP2001544994A patent/JP2003517149A/ja active Pending
- 2000-12-14 CA CA002393766A patent/CA2393766A1/fr not_active Abandoned
- 2000-12-14 AU AU21089/01A patent/AU2108901A/en not_active Abandoned
- 2000-12-14 WO PCT/US2000/034222 patent/WO2001043870A2/fr not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2492674A1 (fr) | 2011-02-28 | 2012-08-29 | Lexogen GmbH | Réseaux de biocapteurs formé par jonctions d'électrodes fonctionnalisées |
WO2012116386A1 (fr) | 2011-02-28 | 2012-09-07 | Lexogen Gmbh | Réseau de biocapteurs formé par des jonctions d'électrodes fonctionnalisées |
Also Published As
Publication number | Publication date |
---|---|
JP2003517149A (ja) | 2003-05-20 |
AU2108901A (en) | 2001-06-25 |
EP1251955A2 (fr) | 2002-10-30 |
WO2001043870A3 (fr) | 2002-02-21 |
WO2001043870A2 (fr) | 2001-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |