AU2021410145A1 - Pharmaceutical composition for topical administration containing epinastine or salt thereof - Google Patents

Pharmaceutical composition for topical administration containing epinastine or salt thereof Download PDF

Info

Publication number
AU2021410145A1
AU2021410145A1 AU2021410145A AU2021410145A AU2021410145A1 AU 2021410145 A1 AU2021410145 A1 AU 2021410145A1 AU 2021410145 A AU2021410145 A AU 2021410145A AU 2021410145 A AU2021410145 A AU 2021410145A AU 2021410145 A1 AU2021410145 A1 AU 2021410145A1
Authority
AU
Australia
Prior art keywords
pharmaceutical composition
epinastine
formulation
salt
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021410145A
Other languages
English (en)
Other versions
AU2021410145A9 (en
Inventor
Yoshihiko ESAKI
Koushi Fujisawa
Toyomi FUJISAWA
Yu KAJIWARA
Naoki Ogura
Koji Sakanaka
Yuko TONE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of AU2021410145A1 publication Critical patent/AU2021410145A1/en
Publication of AU2021410145A9 publication Critical patent/AU2021410145A9/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2021410145A 2020-12-24 2021-12-23 Pharmaceutical composition for topical administration containing epinastine or salt thereof Pending AU2021410145A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2020215231 2020-12-24
JP2020-215231 2020-12-24
JP2021146903 2021-09-09
JP2021-146903 2021-09-09
PCT/JP2021/047886 WO2022138826A1 (ja) 2020-12-24 2021-12-23 エピナスチン又はその塩を含有する塗布投与用医薬組成物

Publications (2)

Publication Number Publication Date
AU2021410145A1 true AU2021410145A1 (en) 2023-07-27
AU2021410145A9 AU2021410145A9 (en) 2024-07-25

Family

ID=82158673

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021410145A Pending AU2021410145A1 (en) 2020-12-24 2021-12-23 Pharmaceutical composition for topical administration containing epinastine or salt thereof

Country Status (7)

Country Link
US (1) US20240074973A1 (https=)
EP (1) EP4268827A4 (https=)
JP (2) JP7124248B1 (https=)
KR (1) KR20230124624A (https=)
AU (1) AU2021410145A1 (https=)
TW (1) TW202241449A (https=)
WO (1) WO2022138826A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025205960A1 (ja) * 2024-03-27 2025-10-02 参天製薬株式会社 エピナスチン又はその塩を含有する経皮投与用医薬組成物と抗アレルギー薬との組み合わせ

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536816A (en) * 1964-09-30 1970-10-27 Atlas Chem Ind Water-in-oil emulsion
US6387383B1 (en) * 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
KR20050092429A (ko) 2003-01-22 2005-09-21 니찌방 가부시기가이샤 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법
US20040247686A1 (en) * 2003-04-04 2004-12-09 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising epinastine for the treatment of skin diseases
JP5021155B2 (ja) * 2003-08-01 2012-09-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング エピナスチンと１種以上のさらなる抗−ｈ１−ヒスタミン類との組合せを含む皮膚疾患治療用製薬組成物
WO2005089803A2 (en) * 2004-03-24 2005-09-29 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment of skin diseases comprising a combination of epinastine and one or more additional minerals or one or more crude drugs
CN101217948A (zh) 2005-07-08 2008-07-09 千寿制药株式会社 包含依匹那丁的透皮吸收眼科制剂
CN101036659A (zh) * 2006-03-13 2007-09-19 张文静 一组盐酸依匹斯汀制剂及其制备方法
EP2056809A1 (en) * 2006-08-28 2009-05-13 Senju Pharmaceutical Co., Ltd. Ophthalmic percutaneous absorption type preparation
US20080194544A1 (en) * 2007-02-08 2008-08-14 Ramesh Krishnamoorthy Aqueous formulations of epinastine for treating allergic rhinitis
KR20240023714A (ko) * 2015-02-02 2024-02-22 산텐 세이야꾸 가부시키가이샤 폴리아프론 및 이의 안검 투여
JP6134853B1 (ja) * 2016-10-28 2017-05-24 参天製薬株式会社 エピナスチン含有点眼液
JP7355539B2 (ja) * 2018-07-20 2023-10-03 ロート製薬株式会社 眼科組成物
JP7458159B2 (ja) * 2018-09-28 2024-03-29 ロート製薬株式会社 眼科組成物

Also Published As

Publication number Publication date
WO2022138826A1 (ja) 2022-06-30
JP7124248B1 (ja) 2022-08-23
TW202241449A (zh) 2022-11-01
EP4268827A4 (en) 2024-12-11
JP2022160664A (ja) 2022-10-19
US20240074973A1 (en) 2024-03-07
KR20230124624A (ko) 2023-08-25
JPWO2022138826A1 (https=) 2022-06-30
AU2021410145A9 (en) 2024-07-25
EP4268827A1 (en) 2023-11-01

Similar Documents

Publication Publication Date Title
US12133836B2 (en) Reduction of adipose tissue
JP6209777B2 (ja) 眼の疾病及び疾患のための組成物及び治療
JP5441058B2 (ja) 四級アンモニウム化合物を含む組成物
CN102341093B (zh) 含前列腺素的阴离子水包油型乳液和其用途
JP7171971B1 (ja) エピナスチン又はその塩と硫黄系抗酸化剤を含有する経皮投与用医薬組成物
JP5722803B2 (ja) プロスタグランジンを含有するカチオン性水中油型エマルジョンおよびその使用
JP7124248B1 (ja) エピナスチン又はその塩を含有する塗布投与用医薬組成物
HK40097614A (en) Pharmaceutical composition for topical administration containing epinastine or salt thereof
CN116669705A (zh) 含有依匹斯汀或其盐的涂布施予用医药组合物
HK40091801A (zh) 含有依匹斯汀或其盐的涂布施予用医药组合物
KR102627092B1 (ko) 수중유 에멀젼
JP2025036319A (ja) クロルフェニラミンマレイン酸塩を含有する医薬組成物
JP2022515569A (ja) フェノルドパムの安定な局所用組成物
JP6084579B2 (ja) タクロリムスを含有する水中油型クリーム状組成物
WO2025205960A1 (ja) エピナスチン又はその塩を含有する経皮投与用医薬組成物と抗アレルギー薬との組み合わせ
HK1166608B (en) Anionic oil-in-water emulsions containing prostaglandins and uses thereof
TW201416076A (zh) 用於眼部疾病或異常之組合物及其治療方法

Legal Events

Date Code Title Description
SREP Specification republished