AU2020455109A1

AU2020455109A1 - Soap/amino acid-type facial cleansing product and preparation method therefor

Info

Publication number: AU2020455109A1
Application number: AU2020455109A
Authority: AU
Inventors: Yuefeng DAI; Guangwen HE; Jingru QIAN; JiaLei YAN; Shaowei YAN
Original assignee: Syoung Cosmetics Manufacturing Co Ltd
Current assignee: Syoung Cosmetics Manufacturing Co Ltd
Priority date: 2020-06-23
Filing date: 2020-11-30
Publication date: 2022-12-01
Also published as: TW202200111A; CN111631974B; CA3180863A1; WO2021258643A1; CN111631974A

Abstract

A soap/amino acid-type facial cleansing product and a preparation method therefor. The product comprises an amino acid surfactant, a soap-based surfactant, an auxiliary surfactant, an auxiliary agent and a solvent, wherein the amino acid surfactant is at least one selected from potassium cocoyl glycinate, sodium cocoyl glycinate, sodium lauroyl sarcosinate, TEA-cocoyl alaninate, sodium cocoyl glutamate, TEA-lauroyl glutamate, sodium lauroyl glutamate and sodium palmoyl glutamate; the soap-based surfactant is at least one selected from potassium cocoate, potassium laurate, potassium myristate, potassium palmitate and potassium stearate; and the auxiliary surfactant is at least one selected from sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide. The product has the characteristics of being low irritation, and having a high cleaning efficiency, a rich foam and a good feeling during use.

Description

English Translation of PCT/CN2020/132836

SOAP/AMINO ACID-TYPE FACIAL CLEANSING PRODUCT AND PREPARATION METHOD THEREFOR FIELD

[0001] The present disclosure relates to the field of cosmetics, and in particular to a soap/amino acid-type facial cleansing product and a preparation method thereof.

BACKGROUND

[0002] Facial cleansing products are cleansing products for facial skin, whose purpose is to remove dirt on the skin, make the skin refreshed, and help maintain the normal physiological state of the skin. Facial cleansing products can remove the skin physiological metabolites such as sebum, stratum corneum flakes and sweat, as well as dust, microorganisms, residues of the cosmetic used and the like, which are attached to the surface of the skin. Among all skin care products, the sale of facial cleansing products accounts for a relatively large proportion.

[0003] According to the differences in the main ingredients used in facial cleansing products on the market, there are currently 7 systems: emulsifying facial cleansing products, surfactant-type facial cleansing products, soap-based type facial cleansing products, MAP (monoalkyl phosphate)-type facial cleansing products, SCI (sodium cocoyl isethionate)-type facial cleansing products, alkyl polyglucoside-type facial cleansing products, and amino acid-type cleansing products. Among them: 1) Emulsifying facial cleansing product: An emulsification system is adopted, and the appearance of the product is similar to that of ordinary cream and lotion. Since it does not contain or contains a small amount of surfactant, it is basically free of foam when used, and has poor cleaning effect. However, due to the use of an emulsification system, it contains a lot of oil, so it has a certain cleansing and emollient effect on skin, for which the skin is smooth after cleaned with it. It has a moisturizing feeling and excellent skin care function, which is suitable for neutral skin. 2) Surfactant-type facial cleansing product: With ordinary surfactant as the main component, it can be made into transparent or pearlescent system, of which the appearance is in the form of a flowable milky liquid or paste, the cleaning effect is moderate, and the foam richness is average. However, it may give consumers a feeling of uncleanness, which is

I

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due to the inherent characteristic of surfactants. In addition, such products are also prone to jelly phenomenon at low temperature, which affects the effect of use by consumers. Such products are suitable for use on various types of skin, and have a low cost. For example, the facial cleansing lotion with disodium sulfosuccinate as the main surfactant on the market belongs to the surfactant-type product. 3) Soap-based type facial cleansing product: Fatty acid soap is used as the main component of this product, and the product has a thick paste-like appearance, generally has a strong pearlescent effect, rich foam and high cleaning efficiency. It is suitable for oily skin, while the disadvantage of it is that it will make skins feel tight or dry after use. If consumers are used to such type of product, they will depend on its cleaning efficiency, and when they use other types of facial cleansing products, they will feel that the cleaning efficiency of other facial cleansing products is not enough. 4) MAP-type facial cleansing product: MAP-type facial cleansing product has exactly the same appearance with regular shampoo, and its use effect is between the surfactant-type facial cleansing product and the soap-based type facial cleansing product. The foam thereof is richer than that of the surfactant-type facial cleansing product but less that of the soap-based type facial cleansing product, and the cleaning efficiency thereof is stronger than that of the surfactant-type facial cleansing product but not stronger than that of the soap-based type facial cleansing product. Therefore, this type of product is suitable for various types of skin. Mildness of the facial cleansing products with MAP as the main surfactant is between the general surfactant-type facial cleansing products and the soap-based type facial cleansing products. It is easy to be cleaned off, and has weak degreasing efficiency, good use performance and good skin feeling. However, the MAP-type product has low viscosity and insufficient product stability, which is easy to form a shear-thickening system and appear jelly-like appearance after thickened. 5) SCI-type facial cleansing product: SCI-type facial cleansing product mildly cleanses the skin with fine and rich foam, which has unique soap-like appearance and medium cost. The foam thereof is rich and fine, which can penetrate into the skin to clean skin. It feels very smooth when used in washing and rinsing, which brings a more comfortable feeling of use. 6) Alkyl polyglucoside-type facial cleansing product: Alkyl polyglucoside (APG) is a biomass surfactant prepared from the reaction of natural renewable raw materials glucose and fatty alcohols without generation of any toxic and harmful by-products, which is a non-ionic surfactant with comprehensive and excellent performance, and also has the characteristics of anionic surfactant. Alkyl polyglucoside surfactant is used as the main ingredient

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of facial cleansing product, the use effect of this facial cleansing product is similar to that of ordinary surfactant-type facial cleansing product, but it has milder characteristic and more comfortable skin feeling, and it is safe and non-irritating, which is often used as a transparent product for infants and targets allergic skin. However, this type of product is difficult to be thickened, the foam thereof is not rich, and the appearance of the product is not very beautiful, which is generally similar to the appearance of shower gel. 7) Amino acid-type cleansing products: Amino acid-type cleansing product is the mildest product, which has characteristics of a comfortable skin feeling during use, and a strong moisturizing feeling after use. There are two types of such products in terms of state. One is paste-like without viscosity and stringiness, which is of pure amino acid system and is thickened by the properties of amino acid itself, but the cost thereof is very high. The other one is similar to the state of viscous shampoo, which is generally thickened by using thickening agents, and it generally cannot be made into pure amino acid system, and must be compounded with other surfactants, so the use effect thereof is slightly poor while the cost thereof is low.

[0004] Although there are many kinds of facial cleansing products on the market, consumers have higher and higher requirements for the feeling of use of facial cleansing products, and the demand for facial cleansing products with low irritation, high cleaning efficiency, rich foam and good feeling of use is also increasing. Therefore, it is very necessary to develop a facial cleansing product that can meet consumers'needs for mildness and cleansing efficiency of the product.

SUMMARY

[0005] In view of this, it is necessary to provide a soap/amino acid-type facial cleansing product, which can meet consumers' requirements for cleansing products with low irritation, high cleaning efficiency, rich foam, and good feeling of use.

[0006] A soap/amino acid-type facial cleansing product, comprising an amino acid surfactant, a soap-based surfactant, an auxiliary surfactant, an auxiliary agent and a solvent;

[0007] wherein, the amino acid surfactant is at least one selected from the group consisting of potassium cocoyl glycinate, sodium cocoyl glycinate, sodium lauroyl sarcosinate, TEA-cocoyl alaninate, sodium cocoyl glutamate, TEA-lauroyl glutamate, sodium lauroyl glutamate and

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sodium palmitoyl glutamate;

[0008] the soap-based surfactant is at least one selected from the group consisting of potassium cocoate, potassium laurate, potassium myristate, potassium palmitate and potassium stearate;

[0009] the auxiliary surfactant is at least one selected from the group consisting of sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide.

[0010] In some embodiments, the amino acid surfactant is potassium cocoyl glycinate and/or sodium cocoyl glycinate; the auxiliary surfactant is at least two selected from the group consisting of sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide.

[0011] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: 0.1%-15% amino acid surfactant, 0.1%-15% soap-based surfactant, 0.1%-20% auxiliary surfactant, 0.5%-20% auxiliary agent and 30%-99% solvent.

[0012] In some embodiments, the auxiliary agent includes a thickening agent, a preservative, and a pH adjusting agent.

[0013] In some embodiments, in the soap/amino acid-type facial cleansing product, the weight percentage of the thickening agent is within the range of 0.2% to 13%, the weight percentage of the preservative is within the range of 0.01% to 3%, and the weight percentage of the pH adjusting agent is within the range of 0.1% to 8%.

[0014] In some embodiments, the thickening agent is at least one selected from the group consisting of acrylate copolymers, sodium chloride, hydroxypropyl methylcellulose, and acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer.

[0015] In some embodiments, the preservative is at least one selected from the group consisting of hydantoin, quaternary ammonium salt-15, bisimidazolidinyl urea, methylparaben, ethylparaben, benzoic acid, sodium benzoate, sorbic acid and salicylic acid.

[0016] In some embodiments, the type of the soap/amino acid-type facial cleansing product includes facial cleansing milk, facial cleansing cream, facial cleansing paste, facial cleansing

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lotion, facial cleansing gel, facial cleansing mousse or facial cleansing soap.

[0017] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 0.1%-10%, potassium cocoate 0.5%-8%, sodium lauroamphoacetate 0.5%-8%, lauryl hydroxysulfobetaine 0.1%-8%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-2%, hydroxypropyl methylcellulose 0.01%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-%, pH adjusting agent 0.1%-I% and water 49%-98%.

[0018] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1%-13%, potassium laurate 0.1%-9%, cocamidopropyl betaine 0.5%-10%, lauryl glucoside 0.1%-8%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-1%, hydroxypropyl methylcellulose 0.01%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-1%, pH adjusting agent 0.1%-I% and water 44%-98%.

[0019] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1%-15%, potassium myristate 0.5%-10%, decyl glucoside 0.1%-7%, cocamide 1%-10%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-0.5%, hydroxypropyl methylcellulose 0.1%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-3%, preservative 0.01%-0.8%, pH adjusting agent 0.05%-3% and water 43%-97%.

[0020] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 2%-12%, potassium stearate 1.5%-15%, dodecyl dimethyl betaine 1%-7%, palm kernel oleamide 0.1%-5%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-1%, hydroxypropyl methylcellulose 0.01%-2%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-1%, pH adjusting agent 0.05%-1% and water 45%-95%.

English Translation of PCT/CN2020/132836

[0021] In some embodiments, the soap/amino acid-type facial cleansing product further comprises at least one of a skin conditioning agent and a functional ingredient.

[0022] Another aspect of the present invention provides a method for preparing a soap/amino acid-type facial cleansing product, comprising the following step:

[0023] mixing together the raw materials of the above soap/amino acid-type facial cleansing product.

[0024] In some embodiments, the preparation method comprises the following steps:

[0025] providing each raw material;

[0026] mixing the amino acid surfactant, the soap-based surfactant, and the auxiliary surfactant evenly, then adding the thickening agent, the pH adjusting agent, the preservative and the remaining other raw materials to the resulting mixture, and mixing evenly.

[0027] The technical solution of the present invention has the following advantages:

[0028] In the soap/amino acid-type facial cleansing product of the present invention, a specific amino acid surfactant compounded with a specific soap-based surfactant is used as the main body, which is supplemented with a mild auxiliary surfactant, so as to make the facial cleansing product have good foaming properties, mildness and low irritation, greatly reducing the irritation caused by soap-based surfactants while ensuring the cleaning efficiency of the product. This is because the soap-based surfactants form soap precipitation with calcium and magnesium ions in hard water during use, which remains on the skin, giving poor feeling of use and irritation. When the soap-based surfactant is compounded with amino acid surfactant, the amino acid surfactant will remove the soap precipitation remained on the skin during use, improving the feeling of use and reducing irritation. In addition, the soap-based surfactant and amino acid surfactant are both anionic surfactants, and the auxiliary surfactants are mostly selected from amphoteric surfactants, i.e., a type of surfactant that has both cationic hydrophilic groups and anionic hydrophilic groups. When the amphoteric surfactant is used alone, its abilities of cleaning, foaming and emulsifier wetting are insufficient, but when compounded with soap-based surfactant and amino acid surfactant, it will have a synergistic effect on foaming, cleaning efficiency, feeling of use, and reducing irritation. .

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[0029] Before use, when this facial cleansing product is rubbed by hands, it is easier to foam and have richer foam than the amino acid-type facial cleansing. During use, when this facial cleansing product is rubbed on face, it feels milder than the soap-based type facial cleansing, and during the washing process, it is easier to be washed than the amino acid-type facial cleansing. After use, it presents stronger cleaning efficiency, fresher skin feeling, and better oil control effect than amino acid-type facial cleansing, and it gives less feelings of tightness, dryness, and irritation than soap-based facial cleansing, which meets the long-term demands of consumers for facial cleansing products with high cleaning efficiency, low irritation, and no feeling of tightness after use.

[0030] Moreover, this product has simpler formula than traditional facial cleansing products, low cost of the formula materials, and good product stability.

BRIEF DESCRIPTION OF DRAWINGS

[0031] FIG. 1 is the comparison diagram of the foaming efficiency of the facial cleansing products of Example 1 and Comparative Examples 1-2 of the present invention;

[0032] FIG. 2 is the comparison diagram of the increase rates of skin water loss using the facial cleansing products of Example 1 and Comparative Examples 1-2 of the present invention;

[0033] FIG. 3 is the comparison diagram of the change rates of skin oil content using the facial cleansing products of Example 1 and Comparative Examples 1-2 of the present invention

[0034] FIG. 4 is the comparison diagram of the feeling of use of the facial cleansing products of Example 1 and Comparative Example 1 of the present invention;

[0035] FIG. 5 is the comparison diagram of the feeling of use of the facial cleansing products of Example 1 and Comparative Example 2 of the present invention.

DETAILED DESCRIPTION

[0036] In order to facilitate understanding of the present invention, the present invention will be described more thoroughly below, and preferred embodiments of the present invention will be

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provided. However, the present invention may be achieved in many different forms and is not limited to the embodiments described herein. On the contrary, these embodiments are provided to help understand the present invention more thoroughly and completely.

[0037] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the technical field of the present invention. The terms used herein in the specification of the present invention are for the purpose of describing specific embodiments only, and are not intended to limit the present invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

[0038] An embodiment of the present invention provides a soap/amino acid-type facial cleansing product, comprising an amino acid surfactant, a soap-based surfactant, an auxiliary surfactant, an auxiliary agent and a solvent; wherein the amino acid surfactant is at least one selected from potassium cocoyl glycinate, sodium cocoyl glycinate, sodium lauroyl sarcosinate, TEA-cocoyl alaninate, sodium cocoyl glutamate, TEA-lauroyl glutamate, sodium lauroyl glutamate and sodium palmitoyl glutamate; the soap-based surfactant is at least one selected from potassium cocoate, potassium laurate, potassium myristate, potassium palmitate and potassium stearate; and the auxiliary surfactant is at least one selected from sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide.

[0039] In the above-mentioned soap/amino acid-type facial cleansing product, a specific amino acid surfactant compounded with a specific soap-based surfactant is used as the main body, which is supplemented with a mild auxiliary surfactant, so as to make the facial cleansing product have good foaming properties, mildness and low irritation, greatly reducing the irritation caused by soap-based surfactants while ensuring the cleaning efficiency of the product. Before use, when this facial cleansing product is rubbed by hands, it is easier to foam and have richer foam than the amino acid-type facial cleansing. During use, when this facial cleansing product is rubbed on face, it feels milder than the soap-based type facial cleansing, and during the washing process, it is easier to be washed than the amino acid-type facial cleansing. After use, it presents stronger cleaning efficiency, fresher skin feeling, and better oil control effect than amino acid-type facial cleansing, and it gives less feelings of tightness, dryness, and irritation than soap-based facial

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cleansing, which meets the long-term demands of consumers for facial cleansing products with high cleaning efficiency, low irritation, and no feeling of tightness after use.

[0040] The characteristics of each component in the above-mentioned soap/amino acid-type facial cleansing product of the present invention are as follows:

[0041] 1) Amino acid surfactant: Amino acid surfactant is a mild and degradable anionic surfactant, which is an amino acid (such as glutamic acid, glycine) salt (sodium salt, potassium salt, triethanolamine salt) of coconut oil (or laurel oil or palm oil) with foaming and decontamination ability. The pH value of amino acid surfactant is 5.5-6.5, which is close to that of human skin, and amino acid is the basic substance that constitutes protein, so it is mild and non-irritating.

[0042] 2) Soap-based surfactant: Soap-based surfactant is an anionic surfactant with low price, its HLB (hydrophilic-lipophilic balance) shows highly hydrophilic, and it has good cleaning and degreasing efficiency.

[0043] 3) Auxiliary surfactant: It can enhance the detergency ability and foaming stability of the amino acid surfactant and soap-based surfactant, improving the cleaning and conditioning abilities of the product. For example, betaine amphoteric surfactants can be compounded with anionic amino acid surfactants and soap-based surfactants to improve safety and increase viscosity. Among them, dodecyl dimethyl betaine (BS-12) is soluble in water at any pH with good detergency ability, good foaming ability and good permeability, it is resistant to hard water, and has good biodegradability, low irritation, and mild performance, and it is compatible well with anions, cations and nonionic surfactants, and also has conditioning, antistatic, softening and sterilizing functions.

[0044] According to the category of hydrophilic groups, amino acid surfactants can be divided into glycine surfactants, sarcosine surfactants, alanine surfactants, and glutamic acid surfactants. The inventors conducted research and analysis on the performance of various amino acid surfactants and found that: in terms of refreshing feeling, glycine surfactants > sarcosine surfactants > alanine surfactants > glutamic acid surfactants; in terms of pH value, glycine surfactants>sarcosine surfactants>alanine surfactants>glutamic acid surfactants. Therefore, when compounded with soap-based surfactants, the preferred sequence of amino acid surfactants for

English Translation of PCT/CN2020/132836

selection is glycine surfactants > sarcosine surfactants > alanine surfactants > glutamic acid surfactants. Meanwhile, although fatty acid salt as surfactant is soluble in water, its solubility and surface activity are easily affected by pH, metal ions such as calcium and magnesium, and temperature factors. It is easily hydrolyzed under acidic conditions so as to lose surface activity and decrease water solubility. Therefore, when selecting amino acids to be compounded, glycine surfactants and sarcosine surfactants whose pH is relatively close to alkaline should be selected first. However, the mildness and washing ability of sarcosine surfactants are slightly inferior to those of glycine surfactants, so glycine surfactants are more preferable.

[0045] In some embodiments, the amino acid surfactant is potassium cocoyl glycinate and/or sodium cocoyl glycinate; the auxiliary surfactant is at least two selected from the group consisting of sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide.

[0046] Further, the auxiliary surfactant is one selected from the group consisting of a combination of sodium lauroamphoacetate and lauryl hydroxysulfobetaine, a combination of cocamidopropyl betaine and lauryl glucoside, a combination of decyl glucoside and cocamide, and a combination of dodecyl dimethyl betaine and palm kernel oleamide.

[0047] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: 0.1%-15% amino acid surfactant, 0.1%-15% soap-based surfactant, 0.1%-20% auxiliary surfactant, 0.5%-20% auxiliary agent and 30%-99% solvent.

[0048] In some embodiments, the auxiliary agent includes a thickening agent, a preservative, and a pH adjusting agent.

[0049] Further, in the soap/amino acid-type facial cleansing product, the weight percentage of the thickening agent is within the range of 0.2% to 13%, the weight percentage of the preservative is within the range of 0.01% to 3%, and the weight percentage of the pH adjusting agent is within the range of 0.1% to 8%.

[0050] It can be understood that a thickening agent, also known as gelling agent, can increase the viscosity or thickness of products to maintain a uniform and stable suspension state or turbid state, or to form gels; in addition, it also has an emulsifying effect. A preservative can inhibit

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microbial activities, prevent product from spoilage, and make products have a certain preservation life. A pH adjusting agent, also known as acidity adjusting agent, is used to maintain or change the acidity or alkalinity of a product.

[0051] In some embodiments, the thickening agent is at least one selected from the group consisting of acrylate copolymers, sodium chloride, hydroxypropyl methylcellulose, and acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer.

[0052] In some embodiments, the thickening agent is a combination of acrylate copolymers, sodium chloride, hydroxypropyl methylcellulose, and acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer. In this way, the combination of the above-mentioned various types of thickening agents can well improve the viscosity of the facial cleansing product of the present invention, while promoting the dispersibility of each component and maintaining the stability of the system.

[0053] In some embodiments, the preservative is at least one selected from the group consisting of hydantoin, quaternary ammonium salt-15, bisimidazolidinyl urea, methylparaben, ethylparaben, benzoic acid, sodium benzoate, sorbic acid and salicylic acid. Preferably, the preservative is hydantoin.

[0054] In some embodiments, the pH adjusting agent is an acid agent, an alkali agent, and a salt with a buffering effect to control the pH value required by the product. In the present examples, the pH adjusting agent is potassium hydroxide.

[0055] In some embodiments, the solvent is water.

[0056] In some embodiments, the type of soap/amino acid-type facial cleansing product includes facial cleansing milk, facial cleansing cream, facial cleansing paste, facial cleansing lotion, facial cleansing gel, facial cleansing mousse or facial cleansing soap.

[0057] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 0.1%-10%, potassium cocoate 0.5%-8%, sodium lauroamphoacetate 0.5%-8%, lauryl hydroxysulfobetaine 0.1%-8%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-2%, hydroxypropyl methylcellulose 0.01%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-%, pH adjusting

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agent 0.1%-I% and water 49%-98%.

[0058] Further, the soap/amino acid-type cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1%-10%, potassium cocoate 2%-8%, sodium lauroamphoacetate 2%-8%, lauryl hydroxysulfobetaine 1%-8%, acrylic acid (acrylate) copolymer 1%-5%, sodium chloride 0.1%-1%, hydroxypropyl methylcellulose 0.01%-0.5%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 1%-5%, preservative 0.1%-0.5%, pH adjusting agent 0.1%-1% and water 53%-90%.

[0059] In this soap/amino acid-type facial cleansing product, a specific soap-based surfactant, an amino acid surfactant and an auxiliary surfactant are cooperated according to the above-mentioned specific ratio, and also combined with a thickening agent and the like. During use, this product will foam rapidly, and the foam is large and rich.

[0060] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1%-13%, potassium laurate 0.1%-9%, cocamidopropyl betaine 0.5%-10%, lauryl glucoside 0.1%-8%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-1%, hydroxypropyl methylcellulose 0.01%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-1%, pH adjusting agent 0.1%-I% and water 44%-98%.

[0061] Further, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 5%-13%, potassium laurate 0.1%-5%, cocamidopropyl betaine 2%-10%, lauryl glucoside 3%-8%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.1%-1%, hydroxypropyl methylcellulose 0.1%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 1%-5%, preservative 0.1%-0.5%, pH adjusting agent 0.1%-1% and water 48.5%-88.5%.

[0062] In this soap/amino acid-type facial cleansing product, the added amount of specific amino acid surfactant and auxiliary surfactant is appropriately increased, and the added amount of specific soap-based surfactant is less than that of amino acid surfactant, so that this facial cleansing product has very low irritation, while having good foaming and cleaning efficiency.

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[0063] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1%-15%, potassium myristate 0.5%-10%, decyl glucoside 0.1%-7%, cocamide 1%-10%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-0.5%, hydroxypropyl methylcellulose 0.1%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-3%, preservative 0.01%-0.8%, pH adjusting agent 0.05%-3% and water 43%-97%.

[0064] Further, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1%-5%, potassium myristate 5%-10%, decyl glucoside 1%-5%, cocamide 1%-5%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-0.5%, hydroxypropyl methylcellulose 0.1%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.5%-3%, preservative 0.1%-0.5%, pH adjusting agent 0.1%-3% and water 59%-91%.

[0065] In this soap/amino acid-type facial cleansing product, the added amount of specific amino acid surfactant and auxiliary surfactant is less than that of soap-based surfactant, so that the product has good foaming ability, good cleaning efficiency, mildness and low irritation.

[0066] In some embodiments, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 2%-12%, potassium stearate 1.5%-15%, dodecyl dimethyl betaine 1%-7%, palm kernel oleamide 0.1%-5%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-1%, hydroxypropyl methylcellulose 0.01%-2%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-1%, pH adjusting agent 0.05%-1% and water 45%-95%.

[0067] Further, the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 2%-12%, potassium stearate 2%-15%, dodecyl dimethyl betaine 1%-5%, palm kernel oleamide 1%-5%, acrylic acid (acrylate) copolymer 1%-5%, sodium chloride 0.1%-%1, hydroxypropyl methylcellulose 0.5%-2%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 1%-5%, preservative 0.01%-1%, pH adjusting agent 0.05%-1% and water

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47%-91%.

[0068] In this soap/amino acid-type facial cleansing product, the components are cooperated according to the above ratio, and the product has good fluidity. During use, it is easily dispersed by water, and is easy to foam and be washed off.

[0069] In some embodiments, the soap/amino acid-type facial cleansing product further comprises at least one of skin conditioning agent and functional ingredient.

[0070] Acceptable skin conditioning agents and functional ingredients are added to the facial cleansing product to impart specific skin feeling, efficacy and claims to the product.

[0071] An embodiment of the present invention also provides a method for preparing a soap/amino acid-type facial cleansing product, comprising mixing together the raw materials of the above soap/amino acid-type facial cleansing product.

[0072] Specifically, the method comprises the following steps S10-S50.

[0073] S10. Preparing each raw material component according to the formula: an amino acid surfactant, a soap-based surfactant, an auxiliary surfactant, a thickening agent, a preservative, a pH adjusting agent, a solvent and other components such as a skin conditioning agent and a functional ingredient.

[0074] S20. Mixing the thickening agent and solvent, homogenizing the mixture at low speed at 1OHz-15Hz for 2 minutes, then stirring and mixing the mixture evenly at 20Hz-4OHz to obtain a first mixture.

[0075] S30. Adding the amino acid surfactant, soap-based surfactant, and auxiliary surfactant to the first mixture, stirring and dispersing the mixture evenly to obtain a second mixture.

[0076] S40. Adding the pH adjusting agent, preservative, and the remaining raw materials such as the skin conditioning agent and functional ingredient to the second mixture while stirring, continuing to stir and mix the mixture evenly, and then homogenizing the mixture at low speed at 1OHz-15Hz for 2 minutes.

[0077] S50. Filtering out the materials.

[0078] The formula of the above preparation method is concise, in which the raw materials are

English Translation of PCT/CN2020/132836

easily accessible, and the cost of the formula materials is low. The obtained product has good stability, in which an amino acid surfactant compounded with a soap-based surfactant is used as the main body, supplemented with an auxiliary surfactant. Before use, when this facial cleansing product is rubbed by hands, it is easier to foam and have richer foam than the amino acid-type facial cleansing. During use, when this facial cleansing product is rubbed on face, it feels milder than the soap-based type facial cleansing, and during the washing process, it is easier to be washed than the amino acid-type facial cleansing. After use, it presents stronger cleaning efficiency, fresher skin feeling, and better oil control effect than amino acid-type facial cleansing, and it gives less feelings of tightness, dryness, and irritation than soap-based facial cleansing, which meets the long-term demands of consumers for facial cleansing products with high cleaning efficiency, and low irritation.

[0079] The following are specific examples

[0080] I. Preparation of soap/amino acid-type facial cleansing

[0081] 1. The formula of the soap/amino acid-type facial cleansings of the Examples and the Comparative Examples of the present invention are shown in Table 1 below.

Cld end

-d Cd Cd C

Cl en0e Cl I I I

C-d

o cd

00

cJd C)

I Cd I

I~~.: 00It)

C/) '0

C) C

ECId

-d C) C) C

Cld end

-d Cd Cd C

Cl en0e Cl I I I

C-d

o cd

00

cJd C)

I Cd I

I~~.: 00It)

C/) '0

C) C

ECId

-d C) C) C en

Cl en C Cl C en Cl i I I I I I 7 - C U H U C

C C -~ I I I I I I en 6 cJ~

H cJ~

en I I I I

I I I I 2 en C

N

en 6 I en I tfl I

I I an i 2 en C

I I I I I an en - 6

In

I I I I I I - en 6

C) -0 -e -~ CJ~ cJ~ C) -~ C) C) C) C) ~ 2o o t ~C) t -

on -Th 0 0 ~ tO -c -~ 0 (90 00 C) _ c~0 _ 0 '-' 0 cc ~ o o -0 Uo 0 0 on C) ~Zon

H

Cld

Cld Cl l

U -d

-d

-~ Cd

Cld Cld

-d

Cld

Cj

cd Cl

Cdl

Cd Cl

Cl

English Translation of PCT/CN2020/132836

[0083] 2. The specific preparation process of the facial cleansing product is as follows:

[0084] 1) The following raw materials were accurately weighed:

[0085] Phase A (thickening phase): water, a thickening agent (acrylic acid (acrylate) copolymers, sodium chloride, hydroxypropyl methylcellulose, and acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer).

[0086] Phase B (surfactant phase): an amino acid surfactant, a soap-based surfactant and/or an auxiliary surfactant.

[0087] Phase C (pH adjusting phase): a pH adjusting agent (potassium hydroxide);

[0088] Phase D (remaining phase): a preservative (DMDM hydantoin), a skin conditioning agent, a functional ingredient, etc.

[0089] 2) The phase B was added to the main pot, homogenized at low speed at 10 Hz - 15 Hz for 2 min, and stirred and mixed evenly at 20 Hz - 40 Hz.

[0090] 3) Phase A was added slowly to the pot while stirring, and the mixture was stirred and dispersed evenly.

[0091] 4) Phase C and phase D were added slowly to the above mixture while stirring, and the obtained mixture was stirred and dispersed evenly.

[0092] 5) The materials were filtered out with filter cloth.

[0093] II. Performance evaluation

[0094] A comparison of the performance tests of the soap/amino acid-type facial cleansing prepared in Example 1 with the amino acid type facial cleanser of Comparative Example 1 and the soap-based type facial cleansing of Comparative Example 2 of the present invention was carried out.

[0095] 1. Evaluation of foaming performance

[0096] 1) Test principle

[0097] Determination of foaming efficiency was carried out according to the national standard GB/T13173.6-91 determination method. The sample was prepared into a test solution of a certain

English Translation of PCT/CN2020/132836

concentration with water of certain hardness. Under a certain temperature condition, 200mL of the test solution flew to the surface of 50mL of the same test solution at the bottom of a graduated cylinder from a height of 90cm, and the measured foam height represented the foaming ability of the sample.

[0098] 2) Test method

[0099] Test reagents: calcium chloride CaCl2; magnesium sulfate MgSO4.7H20

[00100] Test steps:

[00101] Preparation of 150ppm hard water

[00102] 0.0999g calcium chloride and 0.148g magnesium sulfate were weighed and dissolved with distilled water in a 1OOOmL volumetric flask, then the obtained solution was diluted to the mark and shaken well.

[00103] Preparation of test solution

[00104] 2.5g of the sample was weighed and dissolved with 150ppm hard water, the resulting mixture was transferred to a 1OOOmL volumetric flask, diluted to the mark, and shaken well. The solution was then aged in a constant temperature water bath at 40+/-0.5°C, and the total time from the sample was dissolved with water was 30min.

[00105] Determination of foaming efficiency

[00106] When the test solution was being aged, the water pump was started to stabilize the water temperature at 40±0.5°C using the circulating water to pass through the jacket of a graduated measuring tube. The inner wall of the graduated measuring tube was pre-soaked with butyric acid-sulfuric acid solution overnight, and rinsed with distilled water until acid-free. During the test, the inner wall of the graduated measuring tube was first rinsed with distilled water, and then rinsed with the test solution. The rinsing should be complete, and there should be no foam left on the inner wall.

[00107] The test solution was injected from the bottom of the graduated measuring tube to above the 50 mL mark, then the stopcock of the graduated measuring tube was closed, the graduated measuring tube was left to stand still for 5 minutes, and then the stopcock was adjusted so that the solution level was just at the 50 mL mark. A pipette was filled with 200mL of the test

English Translation of PCT/CN2020/132836

solution by suction, which was then placed on the top of the graduated measuring tube. The stopcock of the pipette was then opened to make the solution flow down, when the solution in the pipette was run out, the stopwatch was immediately started, the initial foam height (the average height of the edge and vertex of the foam was taken) was read, and a second reading was recorded at the end of 5 minutes. The above test was repeated 2-3 times with new test solutions, and the tube wall must be washed with the test solution before each test.

[00108] The hardness of water, the concentration of the test solution and the temperature for measurement specified above can be changed according to the requirements of the product standard, but the changes need to be explained.

[00109] Result expression

[00110] The foaming efficiency of the sample is expressed as the number of mm of the initial foam height or the foam height after 5min, and the average value of at least 3 results with errors within the allowable range was taken as the final result, wherein the errors between multiple test results shall not exceed 5mm.

[00111] The experimental test results are shown in Table 2 below:

[00112] Table 2 Sample Comparative Example 2 Comparative Example 1 Example 1 Soap/amino Soap-based type facial Amino acid-type facial acid-type facial cleansing cleansing cleansing

Initial foam Foam height Initial foam Foam height Initial foam Foam height Number of height after 5min height after 5min height after 5min tests 1 152 145 148 148 150 151

2 155 143 145 144 152 153

3 153 146 146 142 154 153

Mean 153.3 144.7 146.3 144.7 152 152.3

[00113] The foam height at 0min was recorded as an evaluation indicator for the foaming efficiency of the tested sample, and the foam height at 5min after foaming was recorded as an evaluation indicator for the foam stability. The test data were processed to obtain a diagram of

English Translation of PCT/CN2020/132836

foaming efficiency and foam stability of different types of facial cleansings as shown in FIG. 1.

[00114] It can be seen from FIG. 1 that the foaming efficiency of the soap-based type facial cleansing was the strongest, followed by the soap/amino acid-type facial cleansing. However, the foam stability of the soap-based type facial cleansing was poor, and a large number of foams thereof burst within 5 minutes, while the soap/amino acid-type facial cleansing has the best foam stability, followed by the amino acid-type facial cleansing. To sum up, the soap/amino acid-type facial cleansing of the present invention has relatively strong foaming efficiency and the best foam stability, which is overall better than soap-based type facial cleansing and amino acid-type facial cleansing in terms of foaming.

[00115] 2. Irritation evaluation

[00116] 1) Test principle: FICK diffusion law: dm/dt=D.A.dp/dx. The amount of water emitted through the skin was directly measured through the water vapor pressure gradient formed by the water loss of the stratum corneum at different bright spots near the epidermis (within about 1 cm) measured by two sets of temperature and humidity sensors. The TEWL value is an important indicator of the quality of the skin barrier, and the lower the TEWL value of the skin is, the better the moisturizing effect is, and vice versa.

[00117] 2)Testmethod

[00118] Test environment: the test environment had a temperature of 22±1°C and a humidity of ±5%, which was real-time dynamically monitored;

[00119] Test volunteers: At least 30 valid volunteers who were aged between 16-65 years old (except pregnant or breastfeeding women) with no serious systemic diseases, no immunodeficiency or autoimmune diseases, and no history of severe allergies to cosmetics, and who had not used hormone drugs and immunosuppressants in the past month, had not participated in other clinical trials, had used the test drugs as required and had complete information. All volunteers should fill out an informed consent form before the test.

[00120] Test steps:

[00121] Pre-test preparation: No product (cosmetics or topical medicines) should be used on the test site 2-3 days before the test. Before the experiment, the subjects needed to agree to clean the

English Translation of PCT/CN2020/132836

inner sides of their two forearms and air dry their forearms naturally. After cleaned, the inner sides of the subjects' two forearms were marked with measurement area. Before the formal test, the subjects should sit still in a standard room for at least 30 minutes, without drinking water, expose their forearms, place their forearms in a test state, and keep relaxed.

[00122] Test process: In the experiment, a 3x3 cm2 test area was marked on the inner side of the left and right arms of the subjects. Multiple areas can be marked on the same arm, and the areas were separated by lcm. The experimental samples and control samples were randomly distributed on the left and right arms. Measurements of skin water loss in the test areas were performed using a probe Tewameter TM300, and the average value of three tests was taken. Nos. 1-3 were the soap-based type facial cleansing samples of Comparative Example 2, Nos. 4-6 were the amino acid-type facial cleansing samples of Comparative Example 1, and Nos. 7-9 were the soap/amino acid-type facial cleansing samples of Example 1. The DO initial value (blank value) of each test area was first measured, then the same amount of the experimental sample and the control sample were applied to the test area of the subjects, which was rubbed for the same number of circles, then the skin was washed and air dried to measure the water loss in the three areas respectively. This test was measured once a week for consecutive 28 days. The test on the same volunteer was done by the same surveyor.

[00123] Test data: According to the experimental design, the skin water loss in each time period was measured respectively, and the increase in skin water loss at each time point was calculated. The greater the increase in skin water loss, the greater the damage of the sample to the skin barrier and the greater the irritation of the sample.

[00124] 3) Test results and analysis:

[00125] The calculation formula of the reduction rate of skin water loss is: W%=(W 2 -Wi)/Wi*100%

[00126] Note: W is the reduction rate of skin water loss, %;

[00127] W2 is the skin water loss value after using the sample;

[00128] W1 is the skin water loss value before using the sample;

[00129] the experimental test results are shown in Table 3 below:

English Translation of PCT/CN2020/132836

[001301 Table 3

Number of subject 1 2 3 4 5 6 7 8 9

day Initial value 18.6 20.2 24 26.6 27.7 25.4 23.3 25.7 29.2

D7 value 21.1 21.9 24.8 25.9 26.9 24.3 23.8 26.8 29.6

7 days Increase rate /% 13.44 8.42 3.33 -2.63 -2.89 -4.33 2.15 4.28 1.37

Mean value 8.40 -3.28 2.60

D14 value 22.3 21.7 25.1 26.4 27.8 26.4 24.2 27.2 30.2 14 dy Increase rate 19.89 7.43 4.58 -0.75 0.36 3.94 3.86 6.61 3.42 days Mean value 10.63 1.18 4.63

D21 value 21.8 22.5 26.3 25.7 27.1 25.8 23.1 26.9 29.8 21 dy Increase rate 17.20 11.39 9.58 -3.38 -2.17 1.57 -0.86 4.67 2.05 days Mean value 12.72 -1.32 1.96

D28 value 21.8 23.6 26.8 26.8 28 26.5 24.7 26.7 30.5 28 dy Increase rate 17.20 16.83 11.67 0.75 1.08 4.33 6.01 3.89 4.45 days Mean value 15.23 2.06 4.78

[00131] The test data in the table above were processed to obtain a diagram of the increase rates of skin water loss for different types of facial cleansings as shown in FIG. 2. As can be seen from FIG. 2, long-term use of the soap-based type facial cleansings increased the water loss of the skin, and gradually damaged the skin barrier, so the soap-based type facial cleansings are more irritating to the skin. Long-term use of the amino acid-type facial cleansing had less damage to the skin barrier and lower irritation to the skin. Long-term use of the soap/amino acid-type facial cleansing had relatively less damage to the skin barrier, and the damage was relatively stable, which would not increase with the increase of the use time. Therefore, the soap/amino acid-type facial cleansing of the present invention is also relatively less irritating to the skin, which is close to the amino acid-type cleansing.

[00132] 3. Cleaning performance evaluation

English Translation of PCT/CN2020/132836

[00133] 1) Test principle

[00134] In the present invention, the evaluation of the oil-absorbing paper using effect was performed using the skin oil tester Sebumeter SM815 of German CK. The oil content test was carried out using the commonly recognized SEBUMETER method. This method is based on the principle of photometer: after a 0.1mm thick special matte tape absorbs the oil on human skin, it will become a translucent tape, so that the amount of light transmission thereof will change, and the more oil it absorbs, the greater the amount of light transmission thereof will be, in which way the content of skin oil can be measured. The biggest advantage of this method is that the test probe is small and easy to use, and any position of the skin can be tested. This is an indirect measurement method of oil gland secretions, and the results thereof can be used to differentiate between different skin types, making it possible to accurately know the oil changes caused by internal and external causes.

[00135] 2) Test method

[00136] Test environment: the test environment had a temperature of 22±1°C and a humidity of +5%, which was real-time dynamically monitored;

[00137] Test volunteers: At least 30 valid volunteers who were aged between 16-65 years old (except pregnant or breastfeeding women) with no serious systemic diseases, no immunodeficiency or autoimmune diseases, and no history of severe allergies to cosmetics, and who had not used hormone drugs and immunosuppressants in the past month, had not participated in other clinical trials, had used the test drugs as required and had complete information. All volunteers should fill out an informed consent form before the test

[00138] Test steps:

[00139] Pre-test preparation: No product (cosmetics or topical medicines) should be used on the test site 2-3 days before the test. Before the experiment, 3 areas of a size of 3cmx3cm were drawn on the subjects' forehead respectively to evaluate the oil content of the skin. For each control sample, the average value of three people was taken to calculate the percentage of oil content increment for relevant evaluation.

[00140] Test process: After the subjects sat in a room with a constant temperature and humidity for 30 minutes, the oil content in the areas marked on their foreheads was measured as the initial

English Translation of PCT/CN2020/132836

value. Then the same amount of the experimental sample and the control sample were applied to the test area of the subjects, which was rubbed for the same number of circles, then the skin was washed and air dried to measure the oil content in the three areas respectively. This test was measured once every 20 min for consecutive 100 min. The test on the same volunteer was done by the same surveyor.

[00141] 3) Test results and analysis

[00142] The calculation formula of the change rate of oil content is: W%=(W 2 -W)/W1 x100O%

[00143] Note: W is the change rate of oil content, %;

[00144] W2 is the skin oil content at 0/20/40/60/80/100min after using the sample;

[00145] Wi is the skin oil content at0min after using the sample;

[00146] the experimental test results are shown in Table 4 below:

[001471 Table 4

Oil content Comparative Example 2 Comparative Example 1 Example 1 Soap/amino acid-type Time Soap-based type facial Amino acid-type facial facial cleansing mm cleansing cleansing Test value Mean value Test value Mean value Test value Mean value

60.21 48.45 52.86

55.53 52.9 50.54 57.79 50.1 55.44 57.63 48.95 62.92

90.1 115.8 101.69

85.34 112.54 98.54 20 87.23 111.01 97.24 86.25 104.69 91.49

95.23 120.34 112.21

98.4 121 109.1 40 101.98 116.58 112.43 112.31 108.4 115.98

English Translation of PCT/CN2020/132836

121.5 127.89 122.2

119 140 131.7 60 115.11 134.89 125.9 104.83 136.78 123.8

144.89 143.55 150.3

80 145.1 145.67 158.9 156.19 142.92 148.25 147.02 166.12 151.53 182.8 205.99 157.28

100 166.9 172.88 189 188.81 163.33 163.67 168.94 171.44 170.4

[00148] The data in Table 4 were processed to obtain the incremental trend data of oil content shown in Table 5 and a diagram of oil content change trend as shown in FIG. 3.

[00149] Table 5

Oil content change rate %

Time min Soap-based type facial Amino acid-type facial Soap/amino acid-type facial cleansing cleansing cleansing 0 0 0 0

20 50.94 121.58 75.40

40 76.47 132.69 102.80

60 99.19 169.24 127.09

80 152.07 211.76 167.41

100 199.15 276.87 195.22

[00150] It can be seen from the above Tables 4-5 and FIG. 3 that the soap-based type facial cleansing had the best oil removal effect. With the growth of time, due to the strong cleansing and degreasing ability of the soap-based type facial cleansing, the skin would secrete more oil in order to achieve the balance of water and oil, so after 60 minutes, the oil secretion of the skin

English Translation of PCT/CN2020/132836

cleaned with the soap-based type facial cleansing would increase rapidly. The amino acid-type facial cleansing had the worst oil removal effect. The soap/amino acid-type facial cleansing of the present invention had a degreasing effect close to that of the soap-based type facial cleansing, and the skin area cleaned with the soap/amino acid-type facial cleansing of the present invention did not present rapid secretion of oil over time.

[00151] 4. Evaluation of the feeling of use

[00152] 1)Testprinciple

[00153] The cosmetic sensory evaluation method was used. Sensory evaluation is a special type of in vivo experiment, and the cosmetic sensory evaluation is an evaluation method that verifies subjectivity such as the skin feeling of cosmetics use. The sensory evaluation mainly includes visual evaluation, olfactory evaluation and tactile evaluation, which respectively relies on visual, olfactory and tactile senses to evaluate appearance, color, smell, skin feeling and the like of the cosmetic. The sensory evaluation methods can be divided into difference test, scale test, descriptive test, preference test and so on. The performances of different types of cosmetics are also different. For example, the performance evaluation of paste, cream and lotion products mainly includes spreadability, moisturizing ability, oily feeling, stickiness, etc., while the performance evaluation of skin cleansing products and shampoo products mainly includes ease of washing, feeling of tightness, etc. In the present invention, the sensory evaluation method of preference test was mainly used, and the evaluation dimensions were mainly 5 dimensions, such as ease of cleaning, no feeling of tightness, no feeling of dryness, smoothness and refreshing feeling. A comparison of sensory tests of the soap/amino acid-type facial cleansing of Example 1 with the soap-based type facial cleansing of Comparative Example 2 and the amino acid-type facial cleansing of Comparative Example 1 was conducted respectively.

[00154] 2) Test method

[00155] Test environment: the test environment had a temperature of 22±1°C and a humidity of 50 ±5%, which was real-time dynamically monitored;

[00156] Test volunteers: Volunteers who were aged between 16-65 years old (except pregnant or breastfeeding women) with no serious systemic diseases, no immunodeficiency or autoimmune diseases, and no history of severe allergies to cosmetics, and who had not used hormone drugs

English Translation of PCT/CN2020/132836

and immunosuppressants in the past month, had not participated in other clinical trials, had used the test drugs as required and had complete information. All volunteers should fill out an informed consent form before the test.

[00157] Test steps:

[00158] Pre-test preparation: The subjects should not use any product (cosmetics or topical medicines) 2-3 days before the test. Before the experiment, the samples to be tested were divided equally, one for each subject.

[00159] Test process: The subjects sat still in a room with a constant temperature and humidity for 30 minutes, and then used the experimental samples and control samples according to their daily using habits. After their skin was washed and air dried, they filled out questionnaires for different samples respectively.

[00160] 3) Test results and analysis

[00161] According to the sensory evaluation results of consumers, the feeling of use of the samples was analyzed and evaluated to obtain the tests data as shown in Table 6 below. A comparison diagram of the feeling of use of the soap/amino acid-type facial cleansing of Example 1 of the present invention and the soap-based type facial cleansing of Comparative Example 2 is shown in FIG. 4, and a comparison diagram of the feeling of use of the soap/amino acid-type facial cleansing of Example 1 of the present invention and the amino acid-type facial cleansing of Comparative Example 1 is show in FIG. 5

[00162] Table 6

Sample

Dimension Example 1 Comparative Example 2 Comparative Example 1 Soap/amino acid-type facial Soap-based type facial Amino acid-type facial cleansing cleansing cleansing

Refreshing 93.89 94.32 92.99 feeling

English Translation of PCT/CN2020/132836

Ease of 94.23 95.1 81.5 cleaning

No feeling 94.99 69.74 88.34 of tightness

No feeling 91.21 71.62 92.19 of dryness

Smoothness 92.83 75.34 91.58

[00163] It can be seen from Table 6 and FIGs. 4 to 5 that the soap/amino acid-type facial cleansing in Example 1 of the present invention was not different from the soap-based type facial cleansing in terms of refreshing feeling and ease of cleaning, but it was obviously better than the soap-based type facial cleansing in terms of smoothness, no feeling of dryness and no feeling of tightness. Although the amino acid-type facial cleansing was superior to the soap/amino acid-type facial cleansing in terms of smoothness, the soap/amino acid-type facial cleansing was superior to the amino acid-type facial cleansing in terms of refreshing feeling, ease of cleaning, no feeling of tightness and no feeling of dryness. To sum up, the soap/amino acid-type facial cleansing in Example 1 of the present invention is generally better than the soap-based type facial cleansing and the amino acid-type facial cleansing in terms of feeling of use.

[00164] The inventors tested various properties of the soap/amino acid-type facial cleansings of Examples 2 to 7, and found that the facial cleansings in Examples 2 to 7 all had good foaming performance, low irritation, good cleaning efficiency and good feeling of use.

[00165] The technical features of the above-described examples can be combined arbitrarily. In order to make description brief, all possible combinations of the technical features in the above-described examples are not described. However, as long as there is no contradiction between the combinations of these technical features, all of them should be regarded as the scope described in this specification.

[00166] The above-mentioned examples only represent several embodiments of the present

English Translation of PCT/CN2020/132836

invention, and the descriptions thereof are specific and detailed, but should not be construed as a limitation on the scope of the present invention. It should be noted that for those of ordinary skill in the art, several modifications and improvements can also be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims

English Translation of PCT/CN2020/132836 CLAIMS

1. A soap/amino acid-type facial cleansing product comprising an amino acid surfactant, a soap-based surfactant, an auxiliary surfactant, an auxiliary agent and a solvent;

wherein the amino acid surfactant is at least one selected from the group consisting of potassium cocoyl glycinate, sodium cocoyl glycinate, sodium lauroyl sarcosinate, TEA-cocoyl alaninate, sodium cocoyl glutamate, TEA-lauroyl glutamate, sodium lauroyl glutamate and sodium palmitoyl glutamate;

the soap-based surfactant is at least one selected from the group consisting of potassium cocoate, potassium laurate, potassium myristate, potassium palmitate and potassium stearate;

the auxiliary surfactant is at least one selected from the group consisting of sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide.

2. The soap/amino acid-type facial cleansing product according to claim 1, wherein the amino acid surfactant is potassium cocoyl glycinate and/or sodium cocoyl glycinate; the auxiliary surfactant is at least two selected from the group consisting of sodium lauroamphoacetate, lauryl hydroxysulfobetaine, cocamidopropyl betaine, lauryl glucoside, decyl glucoside, cocamide, dodecyl dimethyl betaine and palm kernel oleamide.

3. The soap/amino acid-type facial cleansing product according to claim 1, wherein the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: 0.1%-15% amino acid surfactant, 0.1%-15% soap-based surfactant, 0.1%-20% auxiliary surfactant, 0.5%-20% auxiliary agent and 30%-99% solvent.

4. The soap/amino acid-type facial cleansing product according to claim 1, wherein the auxiliary agent includes a thickening agent, a preservative, and a pH adjusting agent.

5. The soap/amino acid-type facial cleansing product according to claim 4, wherein, in the soap/amino acid-type facial cleansing product, the weight percentage of the thickening agent is within the range of 0.2% to 13%, the weight percentage of the preservative is within the range of

English Translation of PCT/CN2020/132836

0.01% to 3%, and the weight percentage of the pH adjusting agent is within the range of 0.1% to 8%.

6. The soap/amino acid-type facial cleansing product according to claim 4, wherein the thickening agent is at least one selected from the group consisting of acrylate copolymers, sodium chloride, hydroxypropyl methylcellulose, and acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer.

7. The soap/amino acid-type facial cleansing product according to claim 4, wherein the preservative is at least one selected from the group consisting of hydantoin, quaternary ammonium salt-15, bisimidazolidinyl urea, methylparaben, ethylparaben, benzoic acid, sodium benzoate, sorbic acid and salicylic acid.

8. The soap/amino acid-type facial cleansing product according to claim 1, wherein the type of the soap/amino acid-type facial cleansing product includes facial cleansing milk, facial cleansing cream, facial cleansing paste, facial cleansing lotion, facial cleansing gel, facial cleansing mousse/foam or facial cleansing soap.

9. The soap/amino acid-type facial cleansing product according to claim 1, wherein the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 0.1%-10%, potassium cocoate 0.5%-8%, sodium lauroamphoacetate 0.5%-8%, lauryl hydroxysulfobetaine 0.1%-8%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-2%, hydroxypropyl methylcellulose 0.01%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%- 5 %, preservative 0.01%-1%, pH adjusting agent 0.1%-I% and water 4 9 %- 9 8 %.

10. The soap/amino acid-type facial cleansing product according to claim 1, wherein the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1-13%, potassium laurate 0.1%- 9 %, cocamidopropyl betaine 0.5%-10%, lauryl glucoside 0.1%- 8 %, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-1%, hydroxypropyl methylcellulose 0.01% -3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%- 5 %, preservative 0.01%-1%, pH adjusting agent 0.1%-I% and water 44%-98%.

11. The soap/amino acid-type facial cleansing product according to claim 1, wherein the

English Translation of PCT/CN2020/132836

soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 1-15%, potassium myristate 0.5%-10%, decyl glucoside 0.1%-7%, cocamide 1%-10%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-0.5%, hydroxypropyl methylcellulose 0.1%-3%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-3%, preservative 0.01%-0.8%, pH adjusting agent 0.05%-3% and water 43%-97%.

12. The soap/amino acid-type facial cleansing product according to claim 1, wherein the soap/amino acid-type facial cleansing product comprises the following components by weight percentage: potassium cocoyl glycinate/sodium cocoyl glycinate 2%-12%, potassium stearate 1.5%-15%, dodecyl dimethyl betaine 1%-7%, palm kernel oleamide 0.1%-5%, acrylic acid (acrylate) copolymer 0.1%-5%, sodium chloride 0.01%-1%, hydroxypropyl methylcellulose 0.01%-2%, acrylic acid (acrylate)/stearyl alcohol polyethers-20 methacrylate cross linked polymer 0.1%-5%, preservative 0.01%-1%, pH adjusting agent 0.05%-l% and water 45%-95%.

13. A method for preparing a soap/amino acid-type facial cleansing product, comprising the following step: mixing together the raw materials of the soap/amino acid-type facial cleansing product according to any one of claims 1 to 12.

14. The method according to claim 13, wherein the method comprises the following steps:

providing each raw material;

mixing the amino acid surfactant, the soap-based surfactant, and the auxiliary surfactant evenly, then adding the thickening agent, the pH adjusting agent, the preservative and the remaining other raw materials to the resulting mixture, and mixing evenly.