CN107714553A - A kind of anti-oxidant mildy wash and preparation method thereof - Google Patents

A kind of anti-oxidant mildy wash and preparation method thereof Download PDF

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Publication number
CN107714553A
CN107714553A CN201711182164.0A CN201711182164A CN107714553A CN 107714553 A CN107714553 A CN 107714553A CN 201711182164 A CN201711182164 A CN 201711182164A CN 107714553 A CN107714553 A CN 107714553A
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parts
potassium
skin
combination
oxidant
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陈映雪
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Dandong Epoch Biological Medicine Science And Technology Co Ltd
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Dandong Epoch Biological Medicine Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
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  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

A kind of anti-oxidant mildy wash of the present invention and preparation method thereof, by 30~80 parts of deionized water, 5~50 parts of surfactant, 5~30 parts of glycerine, 0.01~0.5 part of EDETATE SODIUM, 0~1 part of thickener, 0~2 part of emulsifying agent, grease 0~5 part of mixing, 0.05~1 part of polyacrylamide, 0.01~20 part of blueberry extract, 0.01~1 part of essence, 0.01~2 part of preservative, 0~5 part of emollient are made, while its cleaning skin surface, it can effectively promote free radical to depart from skin surface and remove, prevent skin damage aging.

Description

A kind of anti-oxidant mildy wash and preparation method thereof
Technical field
The present invention relates to daily skin care item, specifically a kind of face cleaning that with the addition of the blueberry extract by flocculation pretreatment Breast.For the harmful free radicals of the face cleaning skin attachment of deep layer removal simultaneously, so as to anti-oxidant to arriving, prevention skin injury aging Effect.
Background technology
Countless free radical is flooded with the environment of human survival, " free radical " is also referred to as in free-radical chemistry, is Refer to the molecule of compound under the external conditions such as photo-thermal, atom with unpaired electron that covalent bond occurs homolysis and formed or Group.Solar irradiation, air pollution, smoking, agricultural chemicals in external environment etc. can all make human body produce more active oxygen radicals, Make nucleic acid mutation, this is human skin aging and ill root.
Free radical shows very active due to containing unpaired electron, can be from neighbouring molecule (including fat, albumen Matter, DNA) on capture electronics, allow and lay oneself open to stable state.So, neighbouring molecule becomes a new freedom again Base, then go to capture electronics again ....The result of such chain reaction, allows the structure of cell to be destroyed, causes cell function to lose Mistake, even gene mutation, death.
Skin surface contains a large amount of free radicals, easily causes redox reaction, accelerates collagen aging in skin, makes Skin follows the string and gloss, produces wrinkle, causes the obscure aging of skin.
The difference for dairy products main component used in of washing one's face at present can be divided into following several systems:
1st, emulsifying mildy wash:Using emulsification system, from the preferable grease of dispersion powder, product appearance and common cream breast Liquid, using being substantially still, cleaning effect is poor, but because using emulsification system, because having certain soothing effect, in being suitable for Dry uses, while is also suitable for those and only uses face cleaning product, without using the consumer of other skin care item.
2nd, common table live body system mildy wash:With conventional surfactants as main component, transparent or pearl can be made Body of light system, outward appearance are flowable emulsion liquid, and cleaning effect is moderate, and foaming abundancy degree is general, but may be caused to consumer The sensation not washed clean, this is the intrinsic characteristic of surfactant, while such product is also easy to low temperature jelly phenomenon occur, The using effect of consumer is influenceed, such product is suitable for various types of skins and used, and product cost is relatively low.
3rd, soap base system mildy wash:Soap belongs to soaps surfactant, and product is the paste outward appearance of stiff, typically Pearl effect is stronger, product foaming abundancy, strong cleaning force, is suitable for Oily use, shortcoming be might have after use it is tight The dry sensation of taut or skin, if a problem is also that the product of consumer's use habit this type, can be to it Cleaning capacity produces dependence, reuses other kinds of mildy wash and has a kind of inadequate sensation of cleaning dynamics forever, meanwhile, Because the Monoethanolamine Lauryl Sulfate of product, degreasing is easily caused to skin, must be produced simultaneously using cream kind skin care using such product Product.
Traditional mildy wash respectively has advantage and disadvantage, is applicable various different skin quality, but functionally all only focused on removal skin table The materials such as face dust, scurf, grease, sweat, cosmetics residual, keep skin cleaning.And in face of ultraviolet, the sky of getting worse Infringement of the free radical pollutant to skin that the reasons such as gas pollution are formed, the problem of causing skin aging, solved without specific aim Scheme.
In existing correlation technique, there are the technical thought for proposing that antioxidant is added in resident skin care item, but free radical Combined with antioxidant, skin can be protected not damaged by initial radical, but the electronics of free radical contention antioxidant, While losing activity, antioxidant loses electronics, produces new unstable radical, and these new free radicals reside in skin Surface, there is the hidden danger for continuing that infringement is produced to skin.
The content of the invention
It is an object of the invention to provide a kind of anti-oxidant mildy wash, while cleaning skin surface, can effectively promote from Skin surface is departed from by base, and removes the free radical for departing from skin surface, prevents skin damage aging.
The anti-oxidant mildy wash preparation method of the present invention:
Raw material is by weight:
(1) by 30~80 parts of deionized water, 5~50 parts of surfactant, 5~30 parts of glycerine, 0.01~0.5 part of EDETATE SODIUM, 0~5 part of 0~1 part of thickener, 0~2 part of emulsifying agent, grease mixing, stirring are warming up to 70-99 DEG C, are then cooled to 45 DEG C~60 ℃;
(2) 0.05~1 part of polyacrylamide, 5~10 parts of deionized water are stirred, to liquid completely it is as clear as crystal after, then 0.01~20 part of blueberry extract is added, continues to stir, it is as clear as crystal to system;
(3) by step(1)Step is added under obtained material stirring(2)In obtained material, 15 DEG C~45 DEG C are cooled to, afterwards Stirring adds 0.01~1 part of essence, 0.01~2 part of preservative, 0~5 part of emollient, is down to room temperature, obtains product.
The present invention is in step(1)In thickener, emulsifying agent, grease can play the sense of regulation skin, improve product appearance etc. Effect, can choose whether to add as the case may be.
The present invention is in step(3)In emollient can play a part of adjusting skin sense, improve use feeling, can be according to tool Body situation chooses whether to add.
The surfactant:For cocounut oil acyl glycine potassium, sodium lauroyl glutamate, Cocoamidopropyl betaine, the moon Laureth potassium phosphate, potassium laurate, potassium myristate, potassium stearate one of which several are applied in combination;
Emulsifying agent:It is applied in combination for monoglyceride, its one kind of the methyl of polyglycereol -3 distearate or two kinds;
Grease:It is applied in combination for Dormant oils, caprylic/capric triglyceride, isononyl isononanoate its one or more;
Preservative:For Phenoxyethanol, Sensiva SC50, Chlorphenesin, one or more of groups therein of methylisothiazolinone Close and use;
Emollient:For urea, ligoglucoside, trehalose, Sodium Hyaluronate, PEG-7 glyceryl cocoates, allantoin therein one Kind or several be applied in combination;
Thickener:For hydroxypropyl methyl cellulose, hydroxyethyl cellulose, carbomer, sodium chloride one or more combination therein Use.
The present invention adds blueberry extract in the aqueous solution of polyacrylamide, and polyacrylamide is high as a kind of nonionic Molecule organic flocculant, have extremely strong adsorption capacity and complicated space network in aqueous.It is main in blueberry extract It is anthocyanidin to want composition, and containing great amount of hydroxy group, which part hydroxyl is combined with the active group on polyacrylamide, in netted knot Adsorbed in structure, the anthocyanidin for having part surplus in solution is not adsorbed by macromolecule organic flocculating agent, individually dissociates in aqueous. The macromolecular network structure of polyacrylamide, adsorbed anthocyanidin, free anthocyanidin in aqueous, three collectively constitute The cubic network system of one removing free radical.The mildy wash formula that this system is added to based on surfactant is worked as In, by removing free radical, concentrate derivative, high-efficiency cleaning removes three steps, effectively remove skin surface free radical and its Derivative, protection skin are without prejudice.
During face cleaning, the anthocyanidin of flocculant adsorption, the anthocyanidin to dissociate in aqueous, as anti-oxidant Agent, met with the free radical of skin surface.Free radical captures the electronics of anthocyanidin, turns into conventional ion, and there is no damage skin The ability of cell.
The anthocyanidin of electronics is lost, is played pendulum, turns into new free radical.Because polyacrylamide has largely Polar group, oxidized anthocyanidin particle, which is produced, reduces potential, eliminates the effect of repulsive force.Make its close to each other, gradually Assemble it is agglomerating, so as to play flocculation.Free oxidation anthocyanidin is adsorbed to be caught, in the traction of macromolecule organic flocculating agent Under, oxidized removing free radical system from unfold, loose network-like structure, be changed into shrinking, coagulate real Floe structure, volume Diminish, density becomes big, is collected as the concentrating structure easily removed.
Polyacrylamide is macromolecule organic polymer, has a large amount of polar groups, these groups and surfactant Polar group has good binding ability.The floc sedimentation surface orientation row that surfactant is formed during free radical is removed Row, make floc sedimentation firmly adsorb on surfactant molecule, are rinsed through clear water and skin surface is left together with surfactant.With While this reaches cleaning skin, free radical, anti-oxidant, delay skin aging effect on removing skin, keep skin Elasticity is smooth, further infringement of the prevention external environment to skin.
Mildy wash of the present invention, based on surfactant, action principle is that surfactant has hydrophilic simultaneously Polar group and oleophylic non-polar group, can make interface state in its solution system that significant change occur.At interface Surface orientation arranges, and adsorbs the pollutant of skin surface, including grease not soluble in water, dust, the horn cell to come off, skin Secretion, cosmetics residual etc..It is set to be combined with the hydrophilic polar group of surfactant with water, so as to play cleaning skin Skin, remove the effect of spot.While a variety of auxiliary components are added, skin sense, state when improvement product uses, stability, smell, So that product obtains more preferable use feeling.
Embodiment
Embodiment 1
(1) by 46 parts of deionized water, 10 parts of cocounut oil acyl glycine potassium, 30 parts of sodium lauroyl glutamate, 10 parts of glycerine, EDETATE SODIUM 0.1 part, the mixing of 1 part of sodium chloride, 80 DEG C are warming up under mixing speed 50rpm, is then cooled to 50 DEG C;
(2) 0.5 part of polyacrylamide is stirred for 5 parts with deionized water, mixing speed 20rpm is completely limpid to liquid It is bright, 20 parts of blueberry extract is added, continues stirring 30 minutes, it is as clear as crystal to system;
(3) by step(1)Under obtained material stirring speed 30rpm, step is added(2)Obtained material, 40 DEG C are cooled to, is stirred Speed 30rpm is mixed, 0.5 part of essence, 2 parts of urea is added, 0.5 part of Phenoxyethanol, is cooled to room temperature, obtains product.
Embodiment 2
(1) by 38 parts of deionized water, 5 parts of Cocoamidopropyl betaine, 12 parts of laureth potassium phosphate, 5 parts of glycerine, EDTA 0.01 part of disodium, 0.1 part of sodium chloride, 0.1 part of carbomer mix, and are warming up to 90 DEG C under mixing speed 50rpm, are then cooled to 55 ℃;
(2) 0.8 part of polyacrylamide is stirred for 10 parts with deionized water, mixing speed 20rpm is completely limpid to liquid It is bright, 25 parts of blueberry extract is added, continues stirring 30 minutes, it is as clear as crystal to system;
(3) by step(1)The material of formation is cooled to 55 DEG C, mixing speed 40rpm, adds step(2)The material of formation, cooling To 43 DEG C, 35rpm is stirred, adds 0.2 part of essence, 0.5 part of Phenoxyethanol, 0.1 part of Chlorphenesin, 0.5 part of ligoglucoside, cooling To room temperature, product is obtained.
Embodiment 3
(1) by 25 parts of deionized water, 8 parts of potassium laurate, 14 parts of potassium myristate, 5 parts of potassium stearate, 15 parts of glycerine, EDTA bis- 0.05 part of sodium, 0.2 part of hydroxyethyl cellulose mix, and are warming up to 85 DEG C under mixing speed 45rpm, are then cooled to 57 DEG C;
(2) 0.6 part of polyacrylamide is stirred for 10 parts with deionized water, mixing speed 20rpm is completely limpid to liquid It is bright, 22 parts of blueberry extract is added, continues stirring 30 minutes, it is as clear as crystal to system;
(3) by step(1)The material of formation is cooled to 57 DEG C, mixing speed 40rpm, adds step(2)The material of formation, cooling To 45 DEG C, 33rpm is stirred, 0.7 part of essence, 0.1 part of methylisothiazolinone, 1 part of trehalose is added, is cooled to room temperature, must produce Product.
Embodiment 4
(1) by 52 parts of deionized water, 6 parts of potassium laurate, 12 parts of potassium myristate, 8 parts of potassium stearate, 10 parts of glycerine, EDTA bis- 0.05 part of sodium, 1 part of monoglyceride, 5 parts of Dormant oils, 0.4 part of hydroxypropyl methyl cellulose are mixed, and 95 are warming up under mixing speed 50rpm DEG C, then it is cooled to 48 DEG C;
(2) 0.2 part of polyacrylamide is stirred for 5 parts with deionized water, mixing speed 20rpm is completely limpid to liquid It is bright, 8 parts of blueberry extract is added, continues stirring 30 minutes, it is as clear as crystal to system;
(3) by step(1)The material of formation is cooled to 48 DEG C of mixing speed 40rpm, adds step(2)The material of formation, cooling To 38 DEG C, 28rpm is stirred, 0.3 part of essence, 0.2 part of Chlorphenesin, 0.01 part of Sodium Hyaluronate is added, is cooled to room temperature, must produce Product.
Embodiment 5
(1) by 32 parts of deionized water, 5 parts of potassium laurate, 30 parts of cocounut oil acyl glycine potassium, 18 parts of glycerine, 0.2 part of EDETATE SODIUM, 0.5 part of the methyl of polyglycereol -3 distearate, 5 parts of caprylic/capric triglyceride, 0.5 part of hydroxypropyl methyl cellulose are mixed Close, be warming up to 95 DEG C under mixing speed 50rpm, be then cooled to 60 DEG C;
(2) 1 part of polyacrylamide is stirred for 15 parts with deionized water, mixing speed 20rpm is completely limpid to liquid It is bright, 18 parts of blueberry extract is added, continues stirring 30 minutes, it is as clear as crystal to system;
(3) by step(1)The material of formation is cooled to 60 DEG C, mixing speed 40rpm, adds step(2)The material of formation, cooling To 42 DEG C, 35rpm is stirred, adds 0.6 part of essence, 0.3 part of Phenoxyethanol, 0.5 part of Sensiva SC50,0.1 part of allantoin, drop Warm to room temperature, obtain product.
Embodiment 6
(1) by 46 parts of deionized water, 3 parts of potassium myristate, 25 parts of cocounut oil acyl glycine potassium, 12 parts of glycerine, EDETATE SODIUM 0.3 Part, 1 part of the methyl of polyglycereol -3 distearate, 5 parts of isononyl isononanoate, 0.5 part of hydroxypropyl methyl cellulose, chlorination 0.2 part of sodium mixes, and is warming up to 88 DEG C under mixing speed 50rpm, is then cooled to 57 DEG C;
(2) by polyacrylamide 0.3 part be stirred with 8 parts of water of deionized water, mixing speed 20rpm is completely limpid to liquid It is transparent, 15 parts of blueberry extract is added, continues stirring 30 minutes, it is as clear as crystal to system;
(3) by step(1)The material of formation is cooled to 57 DEG C, mixing speed 40rpm, adds step(2)The material of formation, cooling To 45 DEG C, 30rpm is stirred, adds 0.3 part of essence, 0.4 part of Phenoxyethanol, 0.1 part of Chlorphenesin, PEG-7 glyceryl cocoates 2 Part, room temperature is cooled to, obtains product.
Experiment detection
By 100 tested members, it is divided into two control groups of one group of 50 people, first group uses anti-oxidant mildy wash of the invention, Second group uses common mildy wash, and tested group membership is investigated after three months, as a result shown, first group has used the present invention For the member of anti-oxidant mildy wash compared with than the second group member using common mildy wash, skin is more bright and clean flexible, it was demonstrated that The present invention can effectively reduce the skin aging problem that environmental damage is brought.

Claims (2)

1. a kind of anti-oxidant mildy wash preparation method, it is characterized in that:
Raw material is by weight:
(1) by 30~80 parts of deionized water, 5~50 parts of surfactant, 5~30 parts of glycerine, 0.01~0.5 part of EDETATE SODIUM, 0~5 part of 0~1 part of thickener, 0~2 part of emulsifying agent, grease mixing, stirring are warming up to 70-99 DEG C, are then cooled to 45 DEG C~60 ℃;
(2) 0.05~1 part of polyacrylamide, 5~10 parts of deionized water are stirred, to liquid completely it is as clear as crystal after, then 0.01~20 part of blueberry extract is added, continues to stir, it is as clear as crystal to system;
(3) by step(1)Step is added under obtained material stirring(2)In obtained material, 15 DEG C~45 DEG C are cooled to, afterwards Stirring adds 0.01~1 part of essence, 0.01~2 part of preservative, 0~5 part of emollient, is down to room temperature, obtains product:
Surfactant:For cocounut oil acyl glycine potassium, sodium lauroyl glutamate, Cocoamidopropyl betaine, laureth Potassium phosphate, potassium laurate, potassium myristate, potassium stearate one of which several are applied in combination;
Emulsifying agent:It is applied in combination for monoglyceride, its one kind of the methyl of polyglycereol -3 distearate or two kinds;
Grease:It is applied in combination for Dormant oils, caprylic/capric triglyceride, isononyl isononanoate its one or more;
Preservative:For Phenoxyethanol, Sensiva SC50, Chlorphenesin, one or more of groups therein of methylisothiazolinone Close and use;
Emollient:For urea, ligoglucoside, trehalose, Sodium Hyaluronate, PEG-7 glyceryl cocoates, allantoin therein one Kind or several be applied in combination;
Thickener:For hydroxypropyl methyl cellulose, hydroxyethyl cellulose, carbomer, sodium chloride one or more combination therein Use.
2. the anti-oxidant mildy wash that preparation method as claimed in claim 1 obtains.
CN201711182164.0A 2017-11-23 2017-11-23 A kind of anti-oxidant mildy wash and preparation method thereof Pending CN107714553A (en)

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CN108653099A (en) * 2018-07-17 2018-10-16 襄阳佰蒂生物科技股份有限公司 A kind of blueberry extract cleanser manufacturing process
CN111067853A (en) * 2020-01-21 2020-04-28 广州睿新生物科技有限公司 Mild and foamy skin cleaning composition and preparation method and application thereof
CN111631974A (en) * 2020-06-23 2020-09-08 湖南御家化妆品制造有限公司 Soap ammonia type face cleaning product and preparation method thereof
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CN108295012A (en) * 2018-04-19 2018-07-20 广州赛莱拉干细胞科技股份有限公司 Anti-aging facial cleanser based on dogfish oil and preparation method thereof
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CN111067853A (en) * 2020-01-21 2020-04-28 广州睿新生物科技有限公司 Mild and foamy skin cleaning composition and preparation method and application thereof
CN111631974A (en) * 2020-06-23 2020-09-08 湖南御家化妆品制造有限公司 Soap ammonia type face cleaning product and preparation method thereof
WO2021258643A1 (en) * 2020-06-23 2021-12-30 湖南御家化妆品制造有限公司 Soap/amino acid-type facial cleansing product and preparation method therefor
CN115554214A (en) * 2022-08-03 2023-01-03 广州丝芬化妆品有限公司 Gel-like oil-controlling skin-cleaning composition and preparation method and application thereof
CN115554214B (en) * 2022-08-03 2024-04-19 广州极男化妆品有限公司 Gel-like oil-control skin-cleaning composition and preparation method and application thereof
CN115554193A (en) * 2022-10-21 2023-01-03 广州环亚化妆品科技股份有限公司 Transparent makeup removing cream and preparation method thereof

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