AU2019394974B2 - Crystalline forms of a compound for treating or preventing gout or hyperuricemia - Google Patents

Crystalline forms of a compound for treating or preventing gout or hyperuricemia

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Publication number
AU2019394974B2
AU2019394974B2 AU2019394974A AU2019394974A AU2019394974B2 AU 2019394974 B2 AU2019394974 B2 AU 2019394974B2 AU 2019394974 A AU2019394974 A AU 2019394974A AU 2019394974 A AU2019394974 A AU 2019394974A AU 2019394974 B2 AU2019394974 B2 AU 2019394974B2
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AU
Australia
Prior art keywords
theta
compound
temperature
benzofuran
crystalline
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Active
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AU2019394974A
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English (en)
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AU2019394974A1 (en
Inventor
Zheng Jane Li
Ruiping Wang
Shunqi Yan
Litain YEH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arthrosi Therapeutics Inc
Original Assignee
Arthrosi Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Arthrosi Therapeutics Inc filed Critical Arthrosi Therapeutics Inc
Publication of AU2019394974A1 publication Critical patent/AU2019394974A1/en
Application granted granted Critical
Publication of AU2019394974B2 publication Critical patent/AU2019394974B2/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2019394974A 2018-12-06 2019-12-05 Crystalline forms of a compound for treating or preventing gout or hyperuricemia Active AU2019394974B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2018119567 2018-12-06
CNPCT/CN2018/119567 2018-12-06
PCT/US2019/064784 WO2020118113A1 (en) 2018-12-06 2019-12-05 Crystalline forms of a compound for treating or preventing gout or hyperuricemia

Publications (2)

Publication Number Publication Date
AU2019394974A1 AU2019394974A1 (en) 2021-07-15
AU2019394974B2 true AU2019394974B2 (en) 2025-08-28

Family

ID=70974392

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019394974A Active AU2019394974B2 (en) 2018-12-06 2019-12-05 Crystalline forms of a compound for treating or preventing gout or hyperuricemia

Country Status (12)

Country Link
US (2) US12145917B2 (https=)
EP (1) EP3890723A4 (https=)
JP (2) JP2022511800A (https=)
KR (1) KR102946486B1 (https=)
CN (1) CN113226302B (https=)
AU (1) AU2019394974B2 (https=)
BR (1) BR112021010708A2 (https=)
EA (1) EA202191545A1 (https=)
IL (1) IL283663B2 (https=)
SG (1) SG11202105745UA (https=)
TW (1) TWI828817B (https=)
WO (1) WO2020118113A1 (https=)

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EP4349414B1 (en) 2014-12-23 2025-10-15 Dyve Biosciences, Inc. Formulations for transdermal administration
EP3484862B1 (en) 2016-07-18 2021-09-01 Arthrosi Therapeutics, Inc. Compounds, compositions and methods for treating or preventing a symptom associated with gout or hyperuricemia
EP3681479B1 (en) 2017-09-15 2024-01-31 Dyve Biosciences, Inc. Sodium bicarbonate for use in the treatment of gout and related disorders
SG11202105743RA (en) 2018-12-06 2021-06-29 Arthrosi Therapeutics Inc Methods for treating or preventing gout or hyperuricemia
KR102946486B1 (ko) 2018-12-06 2026-03-31 아쓰로시 테라퓨틱스, 인크. 통풍 또는 고뇨산혈증의 치료 또는 예방을 위한 화합물의 결정형
WO2020232156A1 (en) * 2019-05-14 2020-11-19 Arthrosi Therapeutics, Inc. Compound for treating gout or hyperuricemia
KR20230024354A (ko) * 2020-06-10 2023-02-20 아쓰로시 테라퓨틱스, 인크. 만성 신장 질환을 치료 또는 예방하는 방법
TW202330485A (zh) * 2021-12-02 2023-08-01 美商安索治療公司 用於治療或預防痛風或高尿酸血症之化合物的結晶形式
WO2023125667A1 (en) * 2021-12-30 2023-07-06 Arthrosi Therapeutics, Inc. Preparation of a compound for the treatment of gout or hyperuricemia

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2018017368A1 (en) * 2016-07-18 2018-01-25 Arthrosi Therapeutics, Llc Compounds, compositions and methods for treating or preventing a sympton associated with gout or hyperuricemia

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Also Published As

Publication number Publication date
CA3121913A1 (en) 2020-06-11
IL283663B1 (en) 2025-08-01
CN113226302B (zh) 2023-08-18
CN113226302A (zh) 2021-08-06
JP2025026857A (ja) 2025-02-26
EA202191545A1 (ru) 2021-10-28
KR20210100677A (ko) 2021-08-17
TW202039453A (zh) 2020-11-01
AU2019394974A1 (en) 2021-07-15
SG11202105745UA (en) 2021-06-29
JP2022511800A (ja) 2022-02-01
EP3890723A4 (en) 2022-08-03
WO2020118113A1 (en) 2020-06-11
IL283663B2 (en) 2025-12-01
EP3890723A1 (en) 2021-10-13
US20250059150A1 (en) 2025-02-20
BR112021010708A2 (pt) 2021-08-24
IL283663A (en) 2021-07-29
US20220024889A1 (en) 2022-01-27
US12145917B2 (en) 2024-11-19
KR102946486B1 (ko) 2026-03-31
TWI828817B (zh) 2024-01-11

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