AU2018303807B2 - Treatment of non-inflammatory lesions - Google Patents

Treatment of non-inflammatory lesions Download PDF

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Publication number
AU2018303807B2
AU2018303807B2 AU2018303807A AU2018303807A AU2018303807B2 AU 2018303807 B2 AU2018303807 B2 AU 2018303807B2 AU 2018303807 A AU2018303807 A AU 2018303807A AU 2018303807 A AU2018303807 A AU 2018303807A AU 2018303807 B2 AU2018303807 B2 AU 2018303807B2
Authority
AU
Australia
Prior art keywords
methyl
pharmaceutically acceptable
acceptable salt
naphthacene
tetrahydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2018303807A
Other languages
English (en)
Other versions
AU2018303807A1 (en
Inventor
David Berk
Alexandre Kaoukhov
Carsten Schmitz
Vilma SNIUKIENE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall LLC
Original Assignee
Almirall LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall LLC filed Critical Almirall LLC
Publication of AU2018303807A1 publication Critical patent/AU2018303807A1/en
Application granted granted Critical
Publication of AU2018303807B2 publication Critical patent/AU2018303807B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2018303807A 2017-07-21 2018-07-20 Treatment of non-inflammatory lesions Active AU2018303807B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762535572P 2017-07-21 2017-07-21
US62/535,572 2017-07-21
PCT/IB2018/000938 WO2019016609A1 (en) 2017-07-21 2018-07-20 TREATMENT OF NON-INFLAMMATORY LESIONS

Publications (2)

Publication Number Publication Date
AU2018303807A1 AU2018303807A1 (en) 2020-02-13
AU2018303807B2 true AU2018303807B2 (en) 2023-08-24

Family

ID=63713912

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018303807A Active AU2018303807B2 (en) 2017-07-21 2018-07-20 Treatment of non-inflammatory lesions

Country Status (13)

Country Link
US (1) US20200222432A1 (enExample)
EP (1) EP3654988B1 (enExample)
JP (1) JP2020527607A (enExample)
KR (1) KR102662461B1 (enExample)
CN (1) CN111343991A (enExample)
AU (1) AU2018303807B2 (enExample)
BR (1) BR112020000968A2 (enExample)
CA (1) CA3070663A1 (enExample)
ES (1) ES2962380T3 (enExample)
IL (1) IL272124A (enExample)
MA (1) MA49641A (enExample)
MX (1) MX2020000816A (enExample)
WO (1) WO2019016609A1 (enExample)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012155146A1 (en) * 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (enExample) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
KR100926326B1 (ko) * 2001-04-05 2009-11-12 콜라제넥스 파마슈티칼스, 인크 여드름 치료 방법
US7704959B2 (en) * 2006-10-03 2010-04-27 Dow Pharmaceutical Sciences Azithromycin for the treatment of nodular acne
PT2109602E (pt) 2006-12-21 2014-05-23 Paratek Pharm Innc Derivados de tetraciclina para o tratamento de infecções bacterianas, virais e parasitárias
SI2120963T1 (sl) * 2006-12-21 2019-02-28 Paratek Pharmaceuticals, Inc. Substituirane spojine tetraciklina za zdravljenje vnetnih kožnih motenj
WO2009141406A1 (en) * 2008-05-21 2009-11-26 Galderma Research & Development Maintenance therapy regimen for treating acne
BRPI0913326C1 (pt) * 2008-06-05 2021-05-25 Dow Pharmaceutical Sciences formulação farmacêuticas tópicas contendo uma baixa concentração de peróxido de benzoíla em suspensão aquosa e um solvente orgânico miscível em água
RU2012104572A (ru) * 2009-07-30 2013-09-10 Аллерган, Инк. Комбинация дапсона с адапаленом
US20140121188A1 (en) * 2009-10-02 2014-05-01 Foamix Ltd. Compositions for the improved treatment of acne and related disorders
IL225240A0 (en) * 2012-03-15 2013-06-27 Meir Eini Use of tetracycline compounds for wound care and skin restoration
GB201615693D0 (en) * 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012155146A1 (en) * 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "ClinicalTrials.gov NCT01628549", 26 June 2012 (2012-06-26), XP055523788, Retrieved from the Internet [retrieved on 20181114] *

Also Published As

Publication number Publication date
JP2020527607A (ja) 2020-09-10
CA3070663A1 (en) 2019-01-24
AU2018303807A1 (en) 2020-02-13
EP3654988A1 (en) 2020-05-27
MX2020000816A (es) 2020-08-17
IL272124A (en) 2020-03-31
US20200222432A1 (en) 2020-07-16
CN111343991A (zh) 2020-06-26
ES2962380T3 (es) 2024-03-18
EP3654988B1 (en) 2023-09-06
WO2019016609A1 (en) 2019-01-24
KR20200031126A (ko) 2020-03-23
BR112020000968A2 (pt) 2020-07-14
KR102662461B1 (ko) 2024-04-30
MA49641A (fr) 2021-06-02

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