AU2016369071B2 - Modified nanopores, compositions comprising the same, and uses thereof - Google Patents

Modified nanopores, compositions comprising the same, and uses thereof Download PDF

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Publication number
AU2016369071B2
AU2016369071B2 AU2016369071A AU2016369071A AU2016369071B2 AU 2016369071 B2 AU2016369071 B2 AU 2016369071B2 AU 2016369071 A AU2016369071 A AU 2016369071A AU 2016369071 A AU2016369071 A AU 2016369071A AU 2016369071 B2 AU2016369071 B2 AU 2016369071B2
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nanopore
clya
amino acid
dna
polynucleotide
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AU2016369071A1 (en
Inventor
Tine BROUNS
Lorenzo FRANCESCHINI
Andrew John Heron
Lakmal Nishantha JAYASINGHE
Giovanni Maglia
Elizabeth Jayne Wallace
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Katholieke Universiteit Leuven
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AU2016369071A 2015-12-08 2016-12-08 Modified nanopores, compositions comprising the same, and uses thereof Active AU2016369071B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562264709P 2015-12-08 2015-12-08
US62/264,709 2015-12-08
PCT/IB2016/001841 WO2017098322A1 (en) 2015-12-08 2016-12-08 Modified nanopores, compositions comprising the same, and uses thereof

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AU2016369071A1 AU2016369071A1 (en) 2018-06-28
AU2016369071B2 true AU2016369071B2 (en) 2022-05-19

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US (1) US10976300B2 (https=)
EP (1) EP3387432B1 (https=)
JP (2) JP7237586B2 (https=)
KR (1) KR102837999B1 (https=)
CN (1) CN109072295B (https=)
AU (1) AU2016369071B2 (https=)
CA (1) CA3011830C (https=)
WO (1) WO2017098322A1 (https=)

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AU2016369071A1 (en) 2018-06-28
CN109072295A (zh) 2018-12-21
EP3387432B1 (en) 2022-09-28
CA3011830A1 (en) 2017-06-15
JP2022046503A (ja) 2022-03-23
US10976300B2 (en) 2021-04-13
JP2019507583A (ja) 2019-03-22
WO2017098322A1 (en) 2017-06-15
KR20180089499A (ko) 2018-08-08
US20180364214A1 (en) 2018-12-20
KR102837999B1 (ko) 2025-07-24
EP3387432A1 (en) 2018-10-17
CA3011830C (en) 2024-11-12
JP7237586B2 (ja) 2023-03-13
CN109072295B (zh) 2022-05-31

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