AU2016367510A1 - Substituted benzazinones as antibacterial compounds - Google Patents
Substituted benzazinones as antibacterial compounds Download PDFInfo
- Publication number
- AU2016367510A1 AU2016367510A1 AU2016367510A AU2016367510A AU2016367510A1 AU 2016367510 A1 AU2016367510 A1 AU 2016367510A1 AU 2016367510 A AU2016367510 A AU 2016367510A AU 2016367510 A AU2016367510 A AU 2016367510A AU 2016367510 A1 AU2016367510 A1 AU 2016367510A1
- Authority
- AU
- Australia
- Prior art keywords
- straight
- branched
- hydroxy
- oxo
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- RWCQPHTWBYIGEV-UHFFFAOYSA-N CC(CCN(C=C(c1cc(-c2ccc(CN(C)C)cc2)ccc11)F)C1=O)(C(NO)=O)S(=O)=O Chemical compound CC(CCN(C=C(c1cc(-c2ccc(CN(C)C)cc2)ccc11)F)C1=O)(C(NO)=O)S(=O)=O RWCQPHTWBYIGEV-UHFFFAOYSA-N 0.000 description 1
- XBDAANKVLLQRSI-UHFFFAOYSA-N CC(CCN(C=Cc1cc(-c(c(F)c2)ccc2OC)ccc11)C1=O)(C(N)=O)[S](=O)=O Chemical compound CC(CCN(C=Cc1cc(-c(c(F)c2)ccc2OC)ccc11)C1=O)(C(N)=O)[S](=O)=O XBDAANKVLLQRSI-UHFFFAOYSA-N 0.000 description 1
- YZSVXJPXNYLPCW-UHFFFAOYSA-N CC(CCN(C=Nc(c1ccc2-c(cc3)ccc3OC)c2F)C1=O)(C(N)=O)S(=O)=O Chemical compound CC(CCN(C=Nc(c1ccc2-c(cc3)ccc3OC)c2F)C1=O)(C(N)=O)S(=O)=O YZSVXJPXNYLPCW-UHFFFAOYSA-N 0.000 description 1
- XDGQWTYLEWXLEW-UHFFFAOYSA-N CC(CCN(C=Nc1cc(-c2ccc(CN3CCOCC3)cc2)ccc11)C1=O)(C(NO)=O)S(=O)=O Chemical compound CC(CCN(C=Nc1cc(-c2ccc(CN3CCOCC3)cc2)ccc11)C1=O)(C(NO)=O)S(=O)=O XDGQWTYLEWXLEW-UHFFFAOYSA-N 0.000 description 1
- KCOVIMIOEPNFRA-UHFFFAOYSA-N CC(CCN(Cc1c2ccc(-c3ccc(CCNCC(F)(F)F)cc3)c1F)C2=O)(C(C)=O)S(=O)=O Chemical compound CC(CCN(Cc1c2ccc(-c3ccc(CCNCC(F)(F)F)cc3)c1F)C2=O)(C(C)=O)S(=O)=O KCOVIMIOEPNFRA-UHFFFAOYSA-N 0.000 description 1
- WWSGUZWKIMUGBX-UHFFFAOYSA-N CC(CCN1N=Nc2cc(-c3ccc(C)cc3F)ccc2C1=O)(C(N)=O)S(=O)=O Chemical compound CC(CCN1N=Nc2cc(-c3ccc(C)cc3F)ccc2C1=O)(C(N)=O)S(=O)=O WWSGUZWKIMUGBX-UHFFFAOYSA-N 0.000 description 1
- QDAUGCYMXMFJBU-JFUPDXTOSA-N CCOC([C@@](C)(CCN(C(C(c1c2ccc(Br)c1)F)OC)C2=O)S(C)(=O)=O)=O Chemical compound CCOC([C@@](C)(CCN(C(C(c1c2ccc(Br)c1)F)OC)C2=O)S(C)(=O)=O)=O QDAUGCYMXMFJBU-JFUPDXTOSA-N 0.000 description 1
- INYVPTFSNVEAGX-QGZVFWFLSA-N CCOC([C@@](C)(CCN(C=C(c1cc(Br)ccc11)F)C1=O)S(C)(=O)=O)=O Chemical compound CCOC([C@@](C)(CCN(C=C(c1cc(Br)ccc11)F)C1=O)S(C)(=O)=O)=O INYVPTFSNVEAGX-QGZVFWFLSA-N 0.000 description 1
- NVDCGPUDIJZJTA-QGZVFWFLSA-N CCOC([C@@](C)(CCN(CCc1cc(B(O)O)ccc11)C1=O)S(C)(=O)=O)=O Chemical compound CCOC([C@@](C)(CCN(CCc1cc(B(O)O)ccc11)C1=O)S(C)(=O)=O)=O NVDCGPUDIJZJTA-QGZVFWFLSA-N 0.000 description 1
- UWBCCOJNAOOUQF-JOCHJYFZSA-N CCc(cc1)ccc1-c(cc1)cc(CN2CC[C@](C)(C(N)=O)S(C)(=O)=O)c1C2=O Chemical compound CCc(cc1)ccc1-c(cc1)cc(CN2CC[C@](C)(C(N)=O)S(C)(=O)=O)c1C2=O UWBCCOJNAOOUQF-JOCHJYFZSA-N 0.000 description 1
- NZJPNALBZPRRIR-UHFFFAOYSA-N COc(cc1)ncc1-c(cc1C(F)=CN2CCC3(C(NO)=O)S(=O)=[O]#C3)ccc1C2=O Chemical compound COc(cc1)ncc1-c(cc1C(F)=CN2CCC3(C(NO)=O)S(=O)=[O]#C3)ccc1C2=O NZJPNALBZPRRIR-UHFFFAOYSA-N 0.000 description 1
- XQWYBTSUFWIUGO-JOCHJYFZSA-N C[C@@](CCN(C=Nc(c1c2)cc(-c3ccc(CCO)cc3)c2F)C1=O)(C(N)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(C=Nc(c1c2)cc(-c3ccc(CCO)cc3)c2F)C1=O)(C(N)=O)S(C)(=O)=O XQWYBTSUFWIUGO-JOCHJYFZSA-N 0.000 description 1
- RASWIZXBIMRTLM-RUZDIDTESA-N C[C@@](CCN(C=Nc(c1c2)cc(-c3ccc(CN(C)C4CC4)cc3)c2F)C1=O)(C(NO)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(C=Nc(c1c2)cc(-c3ccc(CN(C)C4CC4)cc3)c2F)C1=O)(C(NO)=O)S(C)(=O)=O RASWIZXBIMRTLM-RUZDIDTESA-N 0.000 description 1
- MOZVVJASPNZKGL-HXUWFJFHSA-N C[C@@](CCN(C=Nc(c1c2)cc(-c3ccccc3)c2F)C1=O)(C(N)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(C=Nc(c1c2)cc(-c3ccccc3)c2F)C1=O)(C(N)=O)S(C)(=O)=O MOZVVJASPNZKGL-HXUWFJFHSA-N 0.000 description 1
- AEPJXUDAHXWLBT-OAQYLSRUSA-N C[C@@](CCN(C=Nc1cc(-c2ccc(C)c(F)c2)ccc11)C1=O)(C(NO)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(C=Nc1cc(-c2ccc(C)c(F)c2)ccc11)C1=O)(C(NO)=O)S(C)(=O)=O AEPJXUDAHXWLBT-OAQYLSRUSA-N 0.000 description 1
- DIUBHTKMKRJPQW-UUSAFJCLSA-N C[C@@](CCN(C=Nc1cc(C)ccc11)C1=O)(C(NOC1OCCCC1)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(C=Nc1cc(C)ccc11)C1=O)(C(NOC1OCCCC1)=O)S(C)(=O)=O DIUBHTKMKRJPQW-UUSAFJCLSA-N 0.000 description 1
- AZYZAGKACKFRRU-XMMPIXPASA-N C[C@@](CCN(Cc1cc(-c(cc2)ccc2N2CCOCC2)ccc11)C1=O)(C(N)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(Cc1cc(-c(cc2)ccc2N2CCOCC2)ccc11)C1=O)(C(N)=O)S(C)(=O)=O AZYZAGKACKFRRU-XMMPIXPASA-N 0.000 description 1
- GNWZBLNSWDEPJX-OAQYLSRUSA-N C[C@@](CCN(Cc1cc(-c(cc2)ccc2NC)ccc11)C1=O)(C(NO)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(Cc1cc(-c(cc2)ccc2NC)ccc11)C1=O)(C(NO)=O)S(C)(=O)=O GNWZBLNSWDEPJX-OAQYLSRUSA-N 0.000 description 1
- NTRWZMJEOAYOKI-HXUWFJFHSA-N C[C@@](CCN(Cc1cc(-c2ccccc2F)ccc11)C1=O)(C(NO)=O)S(C)(=O)=O Chemical compound C[C@@](CCN(Cc1cc(-c2ccccc2F)ccc11)C1=O)(C(NO)=O)S(C)(=O)=O NTRWZMJEOAYOKI-HXUWFJFHSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2019271952A AU2019271952A1 (en) | 2015-12-08 | 2019-11-27 | Substituted benzazinones as antibacterial compounds |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562264628P | 2015-12-08 | 2015-12-08 | |
| US62/264,628 | 2015-12-08 | ||
| PCT/IB2016/057451 WO2017098440A1 (en) | 2015-12-08 | 2016-12-08 | Substituted benzazinones as antibacterial compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019271952A Division AU2019271952A1 (en) | 2015-12-08 | 2019-11-27 | Substituted benzazinones as antibacterial compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2016367510A1 true AU2016367510A1 (en) | 2018-06-07 |
Family
ID=57680436
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016367510A Abandoned AU2016367510A1 (en) | 2015-12-08 | 2016-12-08 | Substituted benzazinones as antibacterial compounds |
| AU2019271952A Abandoned AU2019271952A1 (en) | 2015-12-08 | 2019-11-27 | Substituted benzazinones as antibacterial compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019271952A Abandoned AU2019271952A1 (en) | 2015-12-08 | 2019-11-27 | Substituted benzazinones as antibacterial compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10781184B2 (https=) |
| EP (1) | EP3386950A1 (https=) |
| JP (1) | JP2019501896A (https=) |
| KR (1) | KR20180088456A (https=) |
| CN (1) | CN108368053A (https=) |
| AU (2) | AU2016367510A1 (https=) |
| BR (1) | BR112018011670A2 (https=) |
| CA (1) | CA3007653A1 (https=) |
| RU (1) | RU2018124788A (https=) |
| WO (1) | WO2017098440A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| AR105646A1 (es) | 2015-08-11 | 2017-10-25 | Actelion Pharmaceuticals Ltd | Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida |
| AR105889A1 (es) | 2015-09-03 | 2017-11-22 | Actelion Pharmaceuticals Ltd | Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos |
| JP6812542B2 (ja) * | 2016-09-28 | 2021-01-13 | ドン−ア エスティ カンパニー リミテッド | テトラヒドロピリジン誘導体および抗菌剤としてのその使用 |
| CN109593066B (zh) * | 2018-12-21 | 2020-06-19 | 上海交通大学 | 一种用于治疗肠道细菌感染的叶酸拮抗剂及其制备与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101076018B1 (ko) * | 2003-01-08 | 2011-10-21 | 유니버시티 오브 워싱톤 | 항균제 |
| TWI519508B (zh) * | 2007-06-12 | 2016-02-01 | Achaogen Inc | 抗菌劑 |
| WO2011073845A1 (en) * | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| EP3134401B1 (en) * | 2014-04-22 | 2018-06-13 | Novartis AG | Isoxazoline hydroxamic acid derivatives as lpxc inhibitors |
| CA2948077A1 (en) * | 2014-05-16 | 2015-11-19 | Actelion Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
-
2016
- 2016-12-08 EP EP16819668.1A patent/EP3386950A1/en not_active Withdrawn
- 2016-12-08 BR BR112018011670A patent/BR112018011670A2/pt not_active Application Discontinuation
- 2016-12-08 RU RU2018124788A patent/RU2018124788A/ru not_active Application Discontinuation
- 2016-12-08 KR KR1020187019079A patent/KR20180088456A/ko not_active Withdrawn
- 2016-12-08 AU AU2016367510A patent/AU2016367510A1/en not_active Abandoned
- 2016-12-08 US US16/060,641 patent/US10781184B2/en not_active Expired - Fee Related
- 2016-12-08 CA CA3007653A patent/CA3007653A1/en not_active Abandoned
- 2016-12-08 WO PCT/IB2016/057451 patent/WO2017098440A1/en not_active Ceased
- 2016-12-08 JP JP2018529622A patent/JP2019501896A/ja active Pending
- 2016-12-08 CN CN201680072228.9A patent/CN108368053A/zh active Pending
-
2019
- 2019-11-27 AU AU2019271952A patent/AU2019271952A1/en not_active Abandoned
-
2020
- 2020-09-08 US US17/014,386 patent/US20210053926A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20180362474A1 (en) | 2018-12-20 |
| BR112018011670A2 (pt) | 2018-11-27 |
| EP3386950A1 (en) | 2018-10-17 |
| RU2018124788A3 (https=) | 2020-03-18 |
| CN108368053A (zh) | 2018-08-03 |
| CA3007653A1 (en) | 2017-06-15 |
| WO2017098440A1 (en) | 2017-06-15 |
| KR20180088456A (ko) | 2018-08-03 |
| US10781184B2 (en) | 2020-09-22 |
| US20210053926A1 (en) | 2021-02-25 |
| AU2019271952A1 (en) | 2019-12-19 |
| RU2018124788A (ru) | 2020-01-15 |
| JP2019501896A (ja) | 2019-01-24 |
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